We have located links that may give you full text access.
Journal Article
Research Support, Non-U.S. Gov't
Impaired antibody response to pneumococcal capsular polysaccharides and phosphorylcholine in adult patients with a history of bacteremic pneumococcal infection.
Clinical Infectious Diseases 1997 September
The serum antibody response after immunization with a pneumococcal vaccine was analyzed in 46 patients with a history of bacteremic pneumococcal infection and in 36 healthy controls. Seven patients with IgG/IgG2 deficiencies had significantly lower preimmunization and postimmunization levels of antibody to pneumococcal capsular polysaccharides (serotypes 3, 6A, 19F, and 23F) and phosphorylcholine than did the control subjects, while the patients with normal IgG/IgG2 levels did not have a deficient antibody response. For the whole patient group, postimmunization levels of antibody against the serotypes that caused the bacteremias were lower than the levels against other tested serotypes (P < .05). Ten patients vs. one control subject were unable to mount a postimmunization antibody response to the four tested serotypes (P < .05). Six of these 10 nonresponding patients had low IgG/IgG2 levels. The results demonstrate that a poor antibody response to vaccination with capsular polysaccharides, often associated with IgG/IgG2 deficiency, is common in patients with a history of bacteremic pneumococcal infections.
Full text links
Related Resources
Trending Papers
A Guide to the Use of Vasopressors and Inotropes for Patients in Shock.Journal of Intensive Care Medicine 2024 April 14
Prevention and treatment of ischaemic and haemorrhagic stroke in people with diabetes mellitus: a focus on glucose control and comorbidities.Diabetologia 2024 April 17
British Society for Rheumatology guideline on management of adult and juvenile onset Sjögren disease.Rheumatology 2024 April 17
Diagnosis and Management of Cardiac Sarcoidosis: A Scientific Statement From the American Heart Association.Circulation 2024 April 19
Albumin: a comprehensive review and practical guideline for clinical use.European Journal of Clinical Pharmacology 2024 April 13
Eosinophilic Esophagitis: Clinical Pearls for Primary Care Providers and Gastroenterologists.Mayo Clinic Proceedings 2024 April
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app