Ohoud Aljuhani, Ghazwa B Korayem, Ali F Altebainawi, Abdullah Al Harthi, Hisham A Badreldin, Muath A Alsalloum, Khalid Eljaaly, Aisha Alharbi, Rowina Aljehani, Ramesh Vishwakarma, Abeer A Alenazi, Mai Alalawi, Abdulrahman Alissa, Kholoud Al Aamer, Huda Al Enazi, Mohammed Almusallam, Abdulaziz Alshehri, Rawan Bukhari, Ghaday Alasmari, Maha M AlQahtani, Sultanah Al Shammari, Hatim O Alsulaymi, Khalid Al Sulaiman
Background: Tocilizumab (TCZ) has been proposed as potential rescue therapy for severe COVID-19. No previous study has primarily assessed the role of TCZ in preventing severe COVID-19-related multiorgan dysfunction. Hence, this multicenter cohort study aimed to evaluate the effectiveness of TCZ early use versus standard of care in preventing severe COVID-19-related multiorgan dysfunction in COVID-19 critically ill patients during intensive care unit (ICU) stay. Methods: A multicenter, retrospective cohort study includes critically ill adult patients with COVID-19 admitted to the ICUs...
January 22, 2023: Journal of Intensive Care Medicine