journal
https://read.qxmd.com/read/37690012/intensive-glycemic-therapy-in-type-2-diabetes-patients-with-cardiac-autonomic-dysfunction-the-accord-trial
#1
JOURNAL ARTICLE
Yiquan Huang, Peihan Xie, Shaozhao Zhang, Menghui Liu, Rihua Huang, Zhenyu Xiong, Xiangbin Zhong, Yifen Lin, Ziwei Zhou, Wenjing Zhang, Yue Guo, Daya Yang, Xiaodong Zhuang, Xinxue Liao
OBJECTIVE: To assess whether the presence of cardiac autonomic dysfunction denoted by low heart rate variability (HRV) modifies the effect of intensive glycemic therapy on outcomes in patients with type 2 diabetes. PATIENTS AND METHODS: This study included 7946 participants in the ACCORD (Action to Control Cardiovascular Risk in Diabetes) trial from January 2001 through June 2009. Heart rate variability measures included standard deviation of all normal-to-normal intervals (SDNN) and root mean square of successive differences between normal-to-normal intervals (rMSSD)...
September 8, 2023: Mayo Clinic Proceedings
https://read.qxmd.com/read/37676199/physical-activity-and-cause-specific-cardiovascular-mortality-among-people-with-and-without-cardiovascular-disease-a-cohort-study-of-0-6-million-us-adults
#2
JOURNAL ARTICLE
Verónica Cabanas-Sánchez, Miguel Angelo Duarte Junior, Carl J Lavie, Carlos Celis-Morales, Fernando Rodríguez-Artalejo, David Martínez-Gómez
OBJECTIVE: To assess the association of physical activity (PA) with cause-specific cardiovascular disease (CVD) mortality among people with preexisting CVD and to analyze the relationship of PA with CVD-related mortality in people without CVD as well as the association of PA with nonspecific CVD mortality in both populations. PARTICIPANTS AND METHODS: Of the total participants in the 1997 through 2018 US National Health Interview Survey waves, 87,959 adults with CVD and 527,185 without CVD were included...
September 5, 2023: Mayo Clinic Proceedings
https://read.qxmd.com/read/37656085/a-nationwide-cross-sectional-survey-of-knowledge-and-practices-of-diabetes-drug-injection-techniques-of-patients-nurses-and-physicians-the-china-it-improve-study
#3
JOURNAL ARTICLE
Lixin Guo, Qiu Zhang, Yaoming Xue, Xingwu Ran, Liming Chen, Sheng Jiang, Dongfang Liu, Qiuhe Ji, Jing Liu
OBJECTIVE: To investigate the knowledge and practices of diabetes drug injection techniques of diabetes patients, nurses, and physicians to support formulating national guidelines for standardized diabetes drug injection techniques. PATIENTS AND METHODS: In this nationwide multicenter cross-sectional survey conducted between November and December 2020, patients, nurses, and physicians were randomly chosen from 250 primary, 150 secondary, and 100 tertiary care hospitals using the stratified cluster sampling method...
August 31, 2023: Mayo Clinic Proceedings
https://read.qxmd.com/read/37632484/outcomes-with-malignancy-associated-high-risk-pulmonary-embolism-a-nationwide-analysis
#4
JOURNAL ARTICLE
Ramy Sedhom, Rafail Beshai, Peter Moussa, Michael Megaly, Amr Mohsen, Dmitry Abramov, Liset Stoletniy, Islam Y Elgendy
OBJECTIVE: To examine the characteristics and outcomes among patients with high-risk pulmonary embolism (PE) and malignancy. PATIENTS AND METHODS: The Nationwide Readmissions Database was used to identify hospitalizations with high-risk PE from January 1, 2016, to December 31, 2019. The main outcome was the difference in all-cause in-hospital mortality. RESULTS: Among 28,547 weighted hospitalizations with high-risk PE, 4,825 (16.9%) had malignancy...
August 25, 2023: Mayo Clinic Proceedings
https://read.qxmd.com/read/37632486/an-environmental-scan-of-consumer-initiated-germline-genetic-testing-for-health-risks
#5
REVIEW
Hannah G Kirby, Heidi L Rehm, Leland E Hull
As patient access to laboratory testing outside the clinic grows, health care providers can expect to confront increasing questions about the utility and interpretation of consumer-initiated genetic testing for health risks. We sought to characterize the marketplace diversity of consumer-initiated germline genetic testing options. An environmental scan was conducted to identify germline genetic testing companies that offer testing for at least one diagnosable health condition and are available for purchase by consumers in the US market without a visit to one's health care provider...
August 23, 2023: Mayo Clinic Proceedings
https://read.qxmd.com/read/37632485/clinical-outcomes-in-metabolically-healthy-and-unhealthy-obese-and-overweight-patients-with-atrial-fibrillation-findings-from-the-gloria-af-registry
#6
JOURNAL ARTICLE
Bernadette Corica, Giulio Francesco Romiti, Marco Proietti, Davide Antonio Mei, Giuseppe Boriani, Tze-Fan Chao, Brian Olshansky, Menno V Huisman, Gregory Y H Lip
OBJECTIVE: To explore the association between metabolic status, body mass index (BMI), and natural history of patients with atrial fibrillation (AF). METHODS: The global, prospective GLORIA-AF Registry Phase II and III included patients with recent diagnosis of AF between November 2011 and December 2014 for Phase II and between January 2014 and December 2016 for Phase III. With this analysis, we categorized patients with AF according to BMI (normal weight [18...
August 9, 2023: Mayo Clinic Proceedings
https://read.qxmd.com/read/37565948/obesity-cardiorenal-comorbidities-and-risk-of-hospitalization-in-patients-with-heart-failure-with-preserved-ejection-fraction
#7
JOURNAL ARTICLE
Camilla S Morgen, Christiane L Haase, Tugce K Oral, Volker Schnecke, Anette Varbo, Barry A Borlaug
OBJECTIVE: To compare clinical features of patients with obesity-related heart failure (HF) with preserved ejection fraction (HFpEF) with those of patients with similar body mass index (BMI) but no HF and to examine the association between degree of obesity and risk for hospitalizations. METHODS: This was a retrospective analysis of 22,750 adults from a large US electronic health care data set (January 1, 2012, through July 31, 2019), including 4975 with HFpEF. Baseline characteristics were compared between patients with HFpEF and a control group matched on BMI, age, sex, and year of BMI record...
August 9, 2023: Mayo Clinic Proceedings
https://read.qxmd.com/read/37589638/association-of-a-mediterranean-lifestyle-with-all-cause-and-cause-specific-mortality-a-prospective-study-from-the-uk-biobank
#8
JOURNAL ARTICLE
Javier Maroto-Rodriguez, Mario Delgado-Velandia, Rosario Ortolá, Aurora Perez-Cornago, Stefanos N Kales, Fernando Rodríguez-Artalejo, Mercedes Sotos-Prieto
OBJECTIVE: To examine the association between the Mediterranean lifestyle and all-cause, cancer, and cardiovascular disease (CVD) mortality in a British population. PATIENTS AND METHODS: We studied 110,799 individuals 40 to 75 years of age from the UK Biobank cohort, free of CVD or cancer between 2009 and 2012 who were followed-up to 2021. The Mediterranean lifestyle was assessed at baseline through the Mediterranean Lifestyle (MEDLIFE) index, derived from the lifestyle questionnaire and diet assessments and comprising three blocks: (1) "Mediterranean food consumption," (2) "Mediterranean dietary habits," and (3) "physical activity, rest, social habits, and conviviality...
August 8, 2023: Mayo Clinic Proceedings
https://read.qxmd.com/read/37542500/outcomes-of-arterial-bypass-with-the-human-acellular-vessel-for-chronic-limb-threatening-ischemia-performed-under-the-fda-expanded-access-program
#9
JOURNAL ARTICLE
Indrani Sen, W Darrin Clouse, Alexis L Lauria, Daniel R Calderon, Peter B Anderson, Randall R DeMartino, Todd E Rasmussen
OBJECTIVE: To report outcomes of the human acellular vessel (HAV) implanted for limb salvage through the Food and Drug Administration (FDA) Expanded Access Program for patients with chronic limb-threatening ischemia with no autologous conduit. METHODS: The HAV is a bioengineered vascular conduit designed with human vascular smooth muscle cells. The product is under regulatory study. From April 2019 to November 2021, the HAV was implanted in 14 patients (12 men; mean age, 62±14 years) at 3 US centers...
August 2, 2023: Mayo Clinic Proceedings
https://read.qxmd.com/read/37480909/prevalence-of-and-risk-factors-for-post-traumatic-headache-in-civilian-patients-after-mild-traumatic-brain-injury-a-track-tbi-study
#10
JOURNAL ARTICLE
Håkan Ashina, David W Dodick, Jason Barber, Nancy R Temkin, Catherine D Chong, Jennifer S Adler, Ken Shubin Stein, Todd J Schwedt, Geoffrey T Manley
OBJECTIVE: To ascertain the prevalence of and risk factors for post-traumatic headache (PTH) attributed to mild traumatic brain injury (mTBI). PATIENTS AND METHODS: A prospective, longitudinal, multicenter cohort study of patients with mTBI and orthopedic trauma controls who were enrolled from February 26, 2014, to August 8, 2018. The baseline assessment was conducted as soon as possible following evaluation at the emergency department. Follow-ups were scheduled at 2 weeks, 3 months, 6 months, and 12 months postinjury...
July 21, 2023: Mayo Clinic Proceedings
https://read.qxmd.com/read/37661155/young-forest-by-laura-wasilowski
#11
JOURNAL ARTICLE
Margaret R Wentz
Art is integrated into the Mayo Clinic environment. Since the original Mayo Clinic Building was finished in 1914, many pieces have been donated or commissioned for patients and staff to enjoy. Each issue of Mayo Clinic Proceedings features a work of art (as interpreted by the author) that is displayed in a building or on the grounds of Mayo Clinic campuses.
September 2023: Mayo Clinic Proceedings
https://read.qxmd.com/read/37661154/hematoxylin-from-logwood-trees-to-microscope-slides
#12
JOURNAL ARTICLE
David P Steensma, Sanam Loghavi, Thomas E Witzig
No abstract text is available yet for this article.
September 2023: Mayo Clinic Proceedings
https://read.qxmd.com/read/37661153/mucoepidermoid-carcinoma
#13
JOURNAL ARTICLE
Rumeal D Whaley, Sounak Gupta, Lori A Erickson
No abstract text is available yet for this article.
September 2023: Mayo Clinic Proceedings
https://read.qxmd.com/read/37661152/hypertriglyceridemia-induced-pseudo-high-anion-gap-metabolic-acidosis-manifesting-as-ischemic-stroke
#14
LETTER
Abdul R Akkawi, Mason Fawcett, Abhiram Challa, Timothy Nguyen, Jennifer Jackson, Richard Muraga
No abstract text is available yet for this article.
September 2023: Mayo Clinic Proceedings
https://read.qxmd.com/read/37661151/empowering-primary-palliative-care-to-sustain-specialist-palliative-care
#15
LETTER
Richard V Guthrie
No abstract text is available yet for this article.
September 2023: Mayo Clinic Proceedings
https://read.qxmd.com/read/37661150/cerebriform-plaques-in-proteus-syndrome
#16
JOURNAL ARTICLE
Jia-Wei Liu, Dong-Lai Ma
No abstract text is available yet for this article.
September 2023: Mayo Clinic Proceedings
https://read.qxmd.com/read/37661149/data-driven-and-technology-enabled-trial-innovations-toward-decentralization-of-clinical-trials-opportunities-and-considerations
#17
REVIEW
Ojasav Sehrawat, Peter A Noseworthy, Konstantinos C Siontis, Tufia C Haddad, John D Halamka, Hongfang Liu
Traditional trial designs have well-recognized inefficiencies and logistical barriers to participation. Decentralized trials and digital health solutions have been suggested as potential solutions and have certainly risen to the challenge during the pandemic. Clinical trial designs are now increasingly data driven. The use of distributed clinical data networks and digitization has helped to fundamentally upgrade existing research systems. A trial design may vary anywhere from fully decentralized to hybrid to traditional on-site...
September 2023: Mayo Clinic Proceedings
https://read.qxmd.com/read/37661148/61-year-old-woman-with-bleeding-bruising-and-myalgias
#18
JOURNAL ARTICLE
Nirosha D Perera, Arjun Lakshman, C Christopher Hook
No abstract text is available yet for this article.
September 2023: Mayo Clinic Proceedings
https://read.qxmd.com/read/37661147/64-year-old-woman-with-headache-vision-changes-and-presyncope
#19
JOURNAL ARTICLE
Artur Schneider, Nikita Jhawar, Razvan Chirila
No abstract text is available yet for this article.
September 2023: Mayo Clinic Proceedings
https://read.qxmd.com/read/37661146/62-year-old-man-with-abdominal-pain-and-cloudy-peritoneal-dialysate
#20
JOURNAL ARTICLE
Alexander Xiao, Saam Dilmaghani, M Nadir Bhuiyan
No abstract text is available yet for this article.
September 2023: Mayo Clinic Proceedings
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