Hanna Kim, Didem Saygin, Christian Douglas, Jesse Wilkerson, Brian Erman, Angela Pistorio, John A McGrath, Ann M Reed, Chester V Oddis, Claudia Bracaglia, Annet van Royen-Kerkhof, Blanca Bica, Pavla Dolezalova, Virginia P L Ferriani, Berit Flato, Ana G Bernard-Medina, Troels Herlin, Frederick W Miller, Jiri Vencovsky, Nicolino Ruperto, Rohit Aggarwal, Lisa G Rider
OBJECTIVES: The 2016 ACR-EULAR Response Criteria for juvenile dermatomyositis (JDM) was developed as a composite measure with differential weights of six core set measures (CSMs) to calculate a Total Improvement Score (TIS). We assessed the contribution of each CSM, representation of muscle-related and patient-reported CSMs towards improvement, and frequency of CSM worsening across myositis response criteria (MRC) categories in validation of MRC. METHODS: Data from JDM patients in the Rituximab in Myositis trial (n = 48), PRINTO JDM trial (n = 139), and consensus patient profiles (n = 273) were included...
March 17, 2023: Rheumatology