Roshan Patel, Casril Liebert, Ali Kirresh, Mahmood Ahmad
No abstract text is available yet for this article.
September 26, 2020: Rheumatology
Andreu Fernández-Codina, Blanca Pinilla, Iago Pinal-Fernández, Iago Carballo, Carlos Feijoo-Massó, María Toledano-Macías, Borja de Miguel-Campo, Eva Fonseca-Aizpuru, Luis Sáez-Comet, Miguel López-Dupla, José Hernández-Rodríguez, Fernando Martínez-Valle
OBJECTIVES: Several IgG4-related disease (IgG4-RD) phenotypes have been proposed and the first set of classification criteria have been recently created. Our objectives were to assess the phenotype distribution and the performance of the classification criteria in Spanish patients as genetic and geographical differences may exist. METHODS: We performed a cross-sectional multicentre study (Registro Español de Enfermedad Relacionada con la IgG4, REERIGG4) with nine participating centres from Spain...
July 13, 2020: Rheumatology
Julio Ramírez, Andrea Cuervo, Raquel Celis, Virginia Ruiz-Esquide, Raul Castellanos-Moreira, José Antonio Narváez, José A Gómez-Puerta, José L Pablos, Raimon Sanmartí, Juan D Cañete
OBJECTIVE: To identify biomarkers of treatment change and radiographic progression in patients with RA under remission. PATIENTS AND METHODS: RA patients in remission (DAS28-ESR <2.6) were selected and followed up for 5 years. An MRI of the dominant hand and an US assessment of knees/hands and serum levels of inflammation/angiogenesis biomarkers were performed at baseline and at 12th month. Synovial biopsies were obtained in patients with Power Doppler signal...
July 12, 2020: Rheumatology
Aishwarya Gopal, Sanket Shah, M B Adarsh, Chengappa Kavadichanda, Vir Singh Negi
No abstract text is available yet for this article.
July 12, 2020: Rheumatology
Andrew N B Weil
No abstract text is available yet for this article.
July 12, 2020: Rheumatology
Sizheng Steven Zhao, Bradley Pittam, David M Hughes
No abstract text is available yet for this article.
July 12, 2020: Rheumatology
Azin Azarfar, Shazia Bég
No abstract text is available yet for this article.
July 12, 2020: Rheumatology
Amber Vanhaecke, Sofie De Schepper, Sabrina Paolino, Lise Heeman, Hanne Callens, Jan Gutermuth, Sara Nguyen, Maurizio Cutolo, Vanessa Smith
OBJECTIVE: SSc and localized sclerosis (LoS) are considered clinically distinct entities. We describe herein the coexistence of SSc and LoS by both a systematic literature review and an observational cohort study of unselected SSc patients. METHODS: Original studies documenting the coexistence of SSc and LoS were identified in three electronic databases by means of a systematic literature search according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines...
July 12, 2020: Rheumatology
Irene E M Bultink, Frank de Vries, Ronald F van Vollenhoven, Arief Lalmohamed
OBJECTIVES: We wanted to estimate the magnitude of the risk from all-cause, cause-specific and sex-specific mortality in patients with SLE and relative risks compared with matched controls and to evaluate the influence of exposure to medication on risk of mortality in SLE. METHODS: We conducted a population-based cohort study using the Clinical Practice Research Datalink, Hospital Episode Statistics and national death certificates (from 1987 to 2012). Each SLE patient (n = 4343) was matched with up to six controls (n = 21 780) by age and sex...
July 12, 2020: Rheumatology
Savvas Andronikou, Jeannette K Kraft, Amaka C Offiah, Jeremy Jones, Hassan Douis, Manigandan Thyagarajan, Christian A Barrera, Andrea Zouvani, Athimalaipet V Ramanan
Chronic recurrent multifocal osteomyelitis (CRMO) is an auto-inflammatory disorder affecting the skeleton of children and adolescents. Whole-body MRI (WBMRI) is key in the diagnosis and follow-up of CRMO. Imaging protocols should include sagittal short Tau inversion recovery of the spine, imaging of the hands and feet, and T1 images for distinguishing normal bone marrow. CRMO lesions can be metaphyseal, epiphyseal and physeal-potentially causing growth disturbance and deformity. Spinal lesions are common, important and can cause vertebral collapse...
July 10, 2020: Rheumatology
Ali S M Jawad
No abstract text is available yet for this article.
July 8, 2020: Rheumatology
Laura E Dedmon
RA is a chronic systemic inflammatory disease that primarily affects the small joints of the hands and feet, and results in a mean reduction in life expectancy of 3-10 years. RA is a multigene disorder with a substantial genetic component and a heritability estimate of 60%. Large-scale Genome-Wide Association Studies (GWAS) and meta-analyses have revealed common disease-associated variants in the population that may contribute cumulatively to RA pathogenesis. This review identifies the most significant genetic variants associated with RA susceptibility to date, with particular focus on the contribution of the HLA class II genes across different ethnic groups...
July 8, 2020: Rheumatology
Arghya Chattopadhyay, Joydeep Samanta, Ashish Jindal, Sanjay Jain
No abstract text is available yet for this article.
July 6, 2020: Rheumatology
Lillian Barra, Janet E Pope, Priscila Pequeno, Farah E Saxena, Mary Bell, Derek Haaland, Jessica Widdifield
No abstract text is available yet for this article.
July 4, 2020: Rheumatology
Lih En Hong, Liza K Phillips, Janice Fletcher, Vidya S Limaye
No abstract text is available yet for this article.
July 2, 2020: Rheumatology
Lingyi Li, Na Lu, Ana Michelle Avina-Galindo, Yufei Zheng, Diane Lacaille, John M Esdaile, Hyon K Choi, J Antonio Aviña-Zubieta
OBJECTIVES: To estimate the overall risk of venous thromboembolism (VTE), pulmonary embolism (PE) and deep vein thrombosis (DVT) among patients newly diagnosed with RA compared with the general population without RA; and to estimate the risk trends of VTE, PE and DVT after RA diagnosis up to 5 years compared with the general population. METHODS: Using previously validated RA case definition, we conducted a matched cohort study using the population-based administrative health database from the province of British Columbia, Canada...
July 2, 2020: Rheumatology
Alexandra Audemard-Verger, Benjamin Terrier
No abstract text is available yet for this article.
July 2, 2020: Rheumatology
Yu Katayama, Yoshinori Matsumoto, Yuriko Yamamura, Yosuke Asano, Keigo Hayashi, Keiji Ohashi, Michiko Morishita, Haruki Watanabe, Mariko Narazaki, Ken-Ei Sada, Jun Wada
No abstract text is available yet for this article.
July 2, 2020: Rheumatology
Renata F Rosa, Michelle Remião Ugolini-Lopes, Ana Paula Rossi Gandara, Margarete B G Vendramini, Kenia Repiso Campanholo, Livia Dutra, Danieli Castro Oliveira de Andrade
OBJECTIVES: Cognitive dysfunction (CD) is a poorly understood non-stroke central neurological manifestation in anti-phospholipid syndrome (APS). Brain-derived neurotrophic factor (BDNF) is a neurotrophin that plays an important role in neural plasticity and could potentially be a biomarker of CD in primary APS (PAPS). The aim of the study is to assess CD in PAPS patients and to evaluate its association with clinical data, anti-phospholipid antibodies and serum BDNF levels. METHODS: This cross-sectional study compared 44 PAPS patients and 20 healthy controls matched for age, gender and education...
July 2, 2020: Rheumatology
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