journal
https://read.qxmd.com/read/38637947/the-clinical-outcomes-and-healthcare-resource-utilization-in-igg4-related-disease-a-claims-based-analysis-of-commercially-insured-adults-in-the-united-states
#1
JOURNAL ARTICLE
Zachary S Wallace, Gandarvaka Miles, Ekaterina Smolkina, Natalia Petruski-Ivleva, Duane Madziva, Krishan Guzzo, Claire Cook, Xiaoqing Fu, Yuqing Zhang, John H Stone, Hyon K Choi
OBJECTIVES: IgG4-related disease (IgG4-RD) can affect nearly any organ and is often treated with glucocorticoids, which contribute to organ damage and toxicity. Comorbidities and healthcare utilization in IgG4-RD are poorly understood. METHODS: We conducted a cohort study using claims data from a United States managed care organization. Incident IgG4-RD cases were identified using a validated algorithm; general population comparators were matched by age, sex, race/ethnicity, and index date...
April 19, 2024: Rheumatology
https://read.qxmd.com/read/38636489/prognostic-factors-for-colchicine-prophylaxis-related-adverse-events-when-initiating-allopurinol-for-gout-retrospective-cohort-study
#2
JOURNAL ARTICLE
Ram Bajpai, Richard Partington, Sara Muller, Harry Forrester, Christian D Mallen, Lorna Clarson, Nishita Padmanabhan, Rebecca Whittle, Edward Roddy
OBJECTIVES: Colchicine is commonly used to prevent flares when starting urate-lowering therapy for gout. Patients with gout are frequently concurrently prescribed other medications (such as statins) that may interact with colchicine, increasing the risk of adverse events. The aim of this study was to describe potential prognostic factors for adverse events in patients prescribed colchicine when initiating allopurinol. METHODS: We conducted a retrospective cohort study in linked UK Clinical Practice Research Datalink and Hospital Episode Statistics datasets...
April 18, 2024: Rheumatology
https://read.qxmd.com/read/38627240/prosthetic-infections-following-tocilizumab-treatment-in-patients-with-rheumatoid-arthritis
#3
JOURNAL ARTICLE
A Louters, M Van Oosterhout, L Burgemeister, N T Jessurun, J A Van Lint
No abstract text is available yet for this article.
April 16, 2024: Rheumatology
https://read.qxmd.com/read/38621708/british-society-for-rheumatology-guideline-on-management-of-adult-and-juvenile-onset-sj%C3%A3-gren-disease
#4
JOURNAL ARTICLE
Elizabeth J Price, Stuart Benjamin, Michele Bombardieri, Simon Bowman, Sara Carty, Coziana Ciurtin, Bridget Crampton, Annabel Dawson, Benjamin A Fisher, Ian Giles, Peter Glennon, Monica Gupta, Katie L Hackett, Genevieve Larkin, Wan-Fai Ng, Athimalaipet V Ramanan, Saad Rassam, Saaeha Rauz, Guy Smith, Nurhan Sutcliffe, Anwar Tappuni, Stephen B Walsh
Sjögren disease (SD) is a chronic, autoimmune disease of unknown aetiology with significant impact on quality of life. Although dryness (sicca) of the eyes and mouth are the classically described features, dryness of other mucosal surfaces and systemic manifestations are common. The key management aim should be to empower the individual to manage their condition-conserving, replacing and stimulating secretions; and preventing damage and suppressing systemic disease activity. This guideline builds on and widens the recommendations developed for the first guideline published in 2017...
April 16, 2024: Rheumatology
https://read.qxmd.com/read/38613847/-i-couldn-t-carry-on-taking-a-drug-like-that-a-qualitative-study-of-patient-perspectives-on-side-effects-from-rheumatology-drugs
#5
JOURNAL ARTICLE
Dorthe B Berthelsen, Sabrina M Nielsen, Marianne U Rasmussen, Marieke Voshaar, Pamela Richards, Susan J Bartlett, Glen S Hazlewood, Beverly J Shea, Peter Tugwell, Torkell Ellingsen, Tanja S Jørgensen, Salome Kristensen, Lee S Simon, Robin Christensen, Caroline A Flurey
OBJECTIVES: There is growing interest in collecting outcome information directly from patients in clinical trials. This study evaluates what patients with rheumatic and musculoskeletal diseases (RMDs) consider important to know about symptomatic side effects they may experience from a new prescription drug. METHODS: Patients with inflammatory arthritis, who had one or more prescribed drugs for their disease for at least 12 months, participated in focus groups and individual interviews...
April 13, 2024: Rheumatology
https://read.qxmd.com/read/38608193/effectiveness-of-intravenous-methylprednisolone-pulse-in-patients-with-severe-microscopic-polyangiitis-and-granulomatosis-with-polyangiitis
#6
JOURNAL ARTICLE
Satoshi Omura, Takashi Kida, Hisashi Noma, Hironori Inoue, Hideaki Sofue, Aki Sakashita, Masatoshi Kadoya, Daiki Nakagomi, Yoshiyuki Abe, Naoho Takizawa, Atsushi Nomura, Yuji Kukida, Naoya Kondo, Yasuhiko Yamano, Takuya Yanagida, Koji Endo, Shintaro Hirata, Kiyoshi Matsui, Tohru Takeuchi, Kunihiro Ichinose, Masaru Kato, Ryo Yanai, Yusuke Matsuo, Yasuhiro Shimojima, Ryo Nishioka, Ryota Okazaki, Tomoaki Takata, Takafumi Ito, Mayuko Moriyama, Ayuko Takatani, Yoshia Miyawaki, Toshiko Ito-Ihara, Nobuyuki Yajima, Takashi Kawaguchi, Aiko Hirano, Kazuki Fujioka, Wataru Fujii, Takahiro Seno, Makoto Wada, Masataka Kohno, Yutaka Kawahito
OBJECTIVES: To evaluate the effectiveness and safety of two different intravenous methylprednisolone (IVMP) pulse doses in patients with severe microscopic polyangiitis (MPA) and granulomatosis with polyangiitis (GPA). METHODS: We emulated a target trial using observational data from the nationwide registry in Japan. Patients with severe glomerulonephritis or diffuse alveolar haemorrhage were selected and pseudo-randomised into three groups using propensity score-based overlap weighting as follows: non-IVMP, IVMP 0...
April 12, 2024: Rheumatology
https://read.qxmd.com/read/38608192/relapsing-igg4-related-disease-presenting-with-unilateral-parotid-mass-and-facial-palsy
#7
JOURNAL ARTICLE
Nehaal Ahmed, Bradly Kimbrough, Matthew Koster
No abstract text is available yet for this article.
April 12, 2024: Rheumatology
https://read.qxmd.com/read/38598432/short-term-effectiveness-of-guselkumab-in-psoriatic-arthritis-patients-and-suggestive-features-of-axial-involvement-results-from-a-real-life-multicentre-cohort
#8
JOURNAL ARTICLE
Piero Ruscitti, Ilenia Pantano, Giulia Cataldi, Martina Gentile, Francesco Arrigoni, Luca Riccio, Sabrina Marrone, Daniele Mauro, Francesco Ursini, Maria Esposito, Antonio Barile, Maria Concetta Fargnoli, Roberto Giacomelli, Francesco Ciccia, Paola Cipriani
OBJECTIVE: To evaluate the short-term effectiveness of guselkumab in patients with psoriatic arthritis (PsA) and suggestive features of axial involvement in a prospective "real-life" multicentre cohort. METHODS: Between June 2022 and June 2023, PsA patients with axial involvement were evaluated if treated at least for 4 months with guselkumab. The effectiveness was evaluated by BASDAI, ASDAS, DAPSA, and achievement of BASDAI ≤ 4, also exploiting predictive factors...
April 10, 2024: Rheumatology
https://read.qxmd.com/read/38597882/a-direct-comparison-in-diagnostic-performance-of-cdus-fdg-pet-ct-and-mri-in-patients-suspected-of-giant-cell-arteritis
#9
JOURNAL ARTICLE
Marieke van Nieuwland, Edgar M Colin, Marloes Vermeer, Nils R L Wagenaar, Onno D Vijlbrief, Jordy K van Zandwijk, Riemer H J A Slart, Hendrik Koffijberg, Erik Groot Jebbink, Kornelis S M van der Geest, Elisabeth Brouwer, Dennis Boumans, Celina Alves
OBJECTIVES: This study directly compares diagnostic performance of Colour Duplex Ultrasound (CDUS), Fluor-18-deoxyglucose Positron Emission Tomography Computed Tomography (FDG-PET/CT) and Magnetic Resonance Imaging (MRI) in patients suspected of giant cell arteritis (GCA). METHODS: Patients with suspected GCA were included in a nested-case control pilot study. CDUS, whole body FDG-PET/CT and cranial MRI were performed within 5 working days after initial clinical evaluation...
April 10, 2024: Rheumatology
https://read.qxmd.com/read/38597875/deep-learning-enables-automatic-detection-of-joint-damage-progression-in-rheumatoid-arthritis-model-development-and-external-validation
#10
JOURNAL ARTICLE
Mikko S Venäläinen, Alexander Biehl, Milja Holstila, Laura Kuusalo, Laura L Elo
OBJECTIVES: Although deep learning has demonstrated substantial potential in automatic quantification of joint damage in rheumatoid arthritis (RA), evidence for detecting longitudinal changes at an individual patient level is lacking. Here, we introduce and externally validate our automated RA scoring algorithm (AuRA), and demonstrate its utility for monitoring radiographic progression in a real-world setting. METHODS: The algorithm, originally developed during the Rheumatoid Arthritis 2-Dialogue for Reverse Engineering Assessment and Methods (RA2-DREAM) challenge, was trained to predict expert-curated Sharp-van der Heijde total scores in hand and foot radiographs from two previous clinical studies (n = 367)...
April 10, 2024: Rheumatology
https://read.qxmd.com/read/38588569/comment-on-systemic-lupus-erythematosus-patients-have-unique-changes-in-serum-metabolic-profiles-across-age-associated-with-cardiometabolic-risk-reply
#11
JOURNAL ARTICLE
Coziana Ciurtin, Elizabeth C Jury, George A Robinson
No abstract text is available yet for this article.
April 8, 2024: Rheumatology
https://read.qxmd.com/read/38588566/hydroxychloroquine-induced-pigmentation-in-rheumatic-diseases-prevalence-clinical-features-and-influencing-factors
#12
JOURNAL ARTICLE
Zi-Jing Yin, Pin Li, Juan Yu, Dachen Zuo, Hongtao Fan, Fayou Li, Juan Wang, Fei Gao, Weiqin Zhao, Shuya Wang, Sha Ma, Jing Wang
OBJECTIVE: To describe the clinical features of Chinese patients with hydroxychloroquine (HCQ)-induced pigmentation and analyze the potential risk factors associated with HCQ-induced pigmentation. METHODS: A cross-sectional study was conducted over a duration of 7 months, during which patients who had received HCQ treatment for >6 months were included. Data was collected through a structured questionnaire that encompassed demographic and geographic characteristics, information on HCQ and concomitant medication usage, sun exposure characteristics, and hyperpigmentation-related characteristics...
April 8, 2024: Rheumatology
https://read.qxmd.com/read/38579198/patients-with-neuropsychiatric-involvement-systemic-lupus-erythematosus-experience-poorer-health-related-quality-of-life-and-more-fatigue-than-systemic-lupus-erythematosus-patients-with-no-neuropsychiatric-involvement-irrespective-of-neuropsychiatric-activity
#13
JOURNAL ARTICLE
Dionysis Nikolopoulos, Nursen Cetrez, Julius Lindblom, Leonardo Palazzo, Yvonne Enman, Ioannis Parodis
OBJECTIVES: Substantial proportions of patients with systemic lupus erythematosus (SLE) report poor health-related quality of life (HRQoL). Our objective was to investigate the impact of neuropsychiatric involvement (NP) in SLE on patient-reported outcomes. METHODS: We analysed data from four phase III trials (BLISS-52, BLISS-76, BLISS-SC, EMBRACE; N = 2968). The neuropsychiatric SLE (NPSLE) group comprised individuals with NP-British Isles Lupus Assessment group (BILAG) A/B/C/D or score in any descriptor of the NP-SLEDAI-2K at baseline (N = 350), while the non-NPSLE group consisted of patients with NP-BILAG E (N = 2618)...
April 5, 2024: Rheumatology
https://read.qxmd.com/read/38579187/incidence-and-risk-factors-of-mental-illnesses-among-patients-with-systemic-autoimmune-rheumatic-diseases-an-18-year-population-based-study
#14
JOURNAL ARTICLE
Wei-Min Chu, Wen-Cheng Chao, Der-Yuan Chen, Wei-Li Ho, Hsin-Hua Chen
OBJECTIVE: This study aimed to assess the incidence and risk factors surrounding mental illnesses in patients diagnosed with systemic autoimmune rheumatic diseases (SARDs). METHODS: This retrospective cohort study used nationwide, population-based claim data taken from Taiwan's National Health Insurance Research Database (NHIRD) to identify patients certified as having a catastrophic illness for Systemic lupus erythematosus (SLE), Rheumatoid arthritis (RA), Systemic sclerosis (SSc), Dermatomyositis (DM), Polymyositis (PM) or Sjogren's syndrome (SS) from the years 2002-2020...
April 5, 2024: Rheumatology
https://read.qxmd.com/read/38579186/setting-the-bar-differently-how-to-navigate-old-and-new-sets-of-criteria-for-the-classification-of-antiphospholipid-syndrome
#15
JOURNAL ARTICLE
Angela Tincani, Laura Andreoli
No abstract text is available yet for this article.
April 5, 2024: Rheumatology
https://read.qxmd.com/read/38574380/responsiveness-and-sensitivity-of-proms-to-change-in-disease-activity-status-in-early-and-established-rheumatoid-arthritis
#16
JOURNAL ARTICLE
Agnes E M Looijen, Elise van Mulligen, Harald E Vonkeman, Annette H M van der Helm-van Mil, Pascal H P de Jong
OBJECTIVES: To determine whether patient reported outcome measures (PROMs) capturing activity limitations, health impact, pain, fatigue and work ability are responsive and sensitive to changes in disease activity status in patients with early and established rheumatoid arthritis (RA). METHODS: All early RA patients (n = 557) from the tREACH-trial and established RA patients (n = 188) from the TARA-trial were included. Both studies were multicentre, single-blinded trials with a treat-to-target management approach...
April 4, 2024: Rheumatology
https://read.qxmd.com/read/38561181/long-term-clinical-outcomes-in-early-rheumatoid-arthritis-that-was-treated-to-target-in-the-best-and-improved-studies
#17
JOURNAL ARTICLE
Sascha L Heckert, Johanna M Maassen, Isabell Nevins, Paul Baudoin, Gerda M Steup-Beekman, Tom W J Huizinga, Sytske Anne Bergstra, Cornelia F Allaart
OBJECTIVES: To assess disease outcomes after 20 and 12 years of patients with rheumatoid (RA) or undifferentiated arthritis (UA), treated-to-target in the BeSt and IMPROVED trials. METHODS: In BeSt (inclusion 2000-2002, duration 10 years), 508 patients with early RA were randomized to: 1. sequential monotherapy, 2. step-up combination therapy, 3. initial csDMARD combination therapy, 4. initial bDMARD/csDMARD combination therapy. The treatment target was low disease activity (DAS ≤ 2...
April 1, 2024: Rheumatology
https://read.qxmd.com/read/38561177/central-retinal-vein-and-cilioretinal-artery-occlusion-in-a-case-of-systemic-sclerosis-treated-with-a-jak-inhibitor-figlotinib
#18
JOURNAL ARTICLE
Kristina Jevnikar, Polona Jaki Mekjavić, Nataša Vidovič Valentinčič, Aleš Ambrožič, Alojzija Hočevar
No abstract text is available yet for this article.
April 1, 2024: Rheumatology
https://read.qxmd.com/read/38552326/serpina3-fga-agp1-itih3-and-saa1-as-novel-biomarkers-for-eosinophilic-granulomatosis-with-polyangiitis-diagnosis-and-activity-assessment
#19
JOURNAL ARTICLE
Yun Liu, Xiufang Kong, Xiao Zhang, Zhihong Chen, Jinghua Wang, Huiyong Chen, Lindi Jiang
OBJECTIVE: To identify novel biomarkers for diagnosis and prediction of active eosinophilic granulomatosis with polyangiitis (EGPA) through data-independent acquisition (DIA) analysis. METHODS: Plasma from 11 EGPA patients and 10 healthy controls (HCs) were analyzed through DIA to identify potential biomarkers. The results were validated in 32 EGPA patients, 24 disease controls (DCs), and 20 HCs using enzyme-linked immunosorbent assay (ELISA). The receiver operating characteristic (ROC) curve was used to assess the diagnostic value of candidate biomarkers...
March 29, 2024: Rheumatology
https://read.qxmd.com/read/38552324/efficacy-of-methylprednisolone-in-very-early-systemic-sclerosis-results-of-the-hit-hard-and-early-randomized-controlled-trial
#20
JOURNAL ARTICLE
Brigit E Kersten, Jacqueline M J Lemmers, Amber Vanhaecke, Arthiha Velauthapillai, Wieneke M T van den Hombergh, Frank H J van den Hoogen, Cornelia H M van den Ende, Vanessa Smith, Madelon C Vonk
OBJECTIVE: We hypothesized that glucocorticoids would induce remission in very early Systemic Sclerosis patients by inhibition of inflammation driving the disease. We examined the efficacy and safety of methylprednisolone in very early Systemic Sclerosis. METHODS: In this trial adults with puffy fingers for less than three years, specific auto-antibodies and meeting the Very Early Diagnosis of Systemic Sclerosis criteria were randomly assigned (2:1) to methylprednisolone 1000 mg intravenously or placebo for 3 consecutive days 3 times with monthly intervals...
March 29, 2024: Rheumatology
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