journal
https://read.qxmd.com/read/32911535/association-of-differentially-expressed-genes-and-autoantibody-type-in-patients-with-systemic-sclerosis
#21
Jun Inamo
OBJECTIVES: The aims of this study were to investigate the relationship between the type of autoantibody and gene expression profile in skin lesions from patients with SSc, and to identify specific dysregulated pathways in SSc patients compared with healthy controls. METHODS: Sixty-one patients with SSc from the Genetics vs Environment in Scleroderma Outcome Study cohort and 36 healthy controls were included in this study. Differentially expressed genes were extracted and functional enrichment and pathway analysis were conducted...
September 10, 2020: Rheumatology
https://read.qxmd.com/read/32911531/epidemiologic-study-of-patients-with-psoriatic-arthritis-in-a-real-world-analysis-a-cohort-study-of-the-french-health-insurance-database
#22
Laura Pina Vegas, Emilie Sbidian, Laetitia Penso, Pascal Claudepierre
OBJECTIVE: PsA is a chronic inflammatory arthritis with heterogeneous disease manifestations. Data on the prevalence of PsA in adults differ widely depending on the study and the country. This study aimed to estimate the prevalence and incidence of PsA in France, characterize comorbidities associated to PsA and identify prescribed treatments. METHODS: This nationwide cohort study involved the administrative healthcare database (Système National des Données de Santé) of the French health insurance scheme linked to the national hospital discharge database...
September 10, 2020: Rheumatology
https://read.qxmd.com/read/32910815/comment-on-eureka-algorithm-predicts-obstetric-risk-and-response-to-treatment-in-women-with-different-subsets-of-anti-phospholipid-antibodies
#23
Joydeep Samanta, Debashish Mishra, Arghya Chattopadhyay, Varun Dhir
No abstract text is available yet for this article.
September 10, 2020: Rheumatology
https://read.qxmd.com/read/32910811/comment-on-eureka-algorithm-predicts-obstetric-risk-and-response-to-treatment-in-women-with-different-subsets-of-anti-phospholipid-antibodies-reply
#24
Cecilia Beatrice Chighizola, Francesca Pregnolato
No abstract text is available yet for this article.
September 10, 2020: Rheumatology
https://read.qxmd.com/read/32910186/a-unique-case-of-co-existent-sarcoidosis-and-immune-mediated-necrotizing-myopathy
#25
Louise I M Koller-Smith, Sonja L Nagel
No abstract text is available yet for this article.
September 10, 2020: Rheumatology
https://read.qxmd.com/read/32910183/dorsal-horn-disinhibition-and-movement-induced-behaviour-in-a-rat-model-of-inflammatory-arthritis
#26
Samantha Locke, Noosha Yousefpour, Alfredo Ribeiro-da-Silva
OBJECTIVES: Alterations beyond joint inflammation such as changes in dorsal horn (DH) excitability contribute to pain in inflammatory arthritis (IA). More complete understanding of specific underlying mechanisms will be important to define novel targets for the treatment of IA pain. Pre-clinical models are useful, but relevant pain assays are vital for successful clinical translation. For this purpose, a method is presented to assess movement-induced pain-related behaviour changes that was subsequently used to investigate DH disinhibition in IA...
September 10, 2020: Rheumatology
https://read.qxmd.com/read/32910153/muscle-deterioration-due-to-rheumatoid-arthritis-assessment-by-quantitative-mri-and-strength-testing
#27
Matthew Farrow, John Biglands, Steven Tanner, Elizabeth M A Hensor, Maya H Buch, Paul Emery, Ai Lyn Tan
OBJECTIVES: RA patients often present with low muscle mass and decreased strength. Quantitative MRI offers a non-invasive measurement of muscle status. This study assessed whether MRI-based measurements of T2, fat fraction, diffusion tensor imaging and muscle volume can detect differences between the thigh muscles of RA patients and healthy controls, and assessed the muscle phenotype of different disease stages. METHODS: Thirty-nine RA patients (13 'new RA'-newly diagnosed, treatment naïve, 13 'active RA'-persistent DAS28 >3...
September 10, 2020: Rheumatology
https://read.qxmd.com/read/32910152/efficacy-and-serious-adverse-events-profile-of-the-adjuvanted-recombinant-zoster-vaccine-in-adults-with-pre-existing-potential-immune-mediated-diseases-a-pooled-post-hoc-analysis-on-two-parallel-randomized-trials
#28
Alemnew F Dagnew, Debora Rausch, Caroline Hervé, Toufik Zahaf, Myron J Levin, Anne Schuind
OBJECTIVE: In the ZOE-50 (NCT01165177) and ZOE-70 (NCT01165229) phase 3 clinical trials, the adjuvanted recombinant zoster vaccine (RZV) demonstrated ≥90% efficacy in preventing herpes zoster (HZ) in all age groups ≥50 years. Given the increased HZ risk associated with certain underlying autoimmune diseases or their treatment regimes, we conducted a post hoc analysis of RZV's efficacy against HZ and safety profile [specifically, the occurrence of serious adverse events (SAEs)] in ZOE-50/70 participants who reported pre-existing potential immune-mediated diseases (pIMDs) at enrolment and were not on immunosuppressive therapies...
September 10, 2020: Rheumatology
https://read.qxmd.com/read/32910145/study-of-mirna-interactome-in-active-rheumatoid-arthritis-patients-reveals-key-pathogenic-roles-of-dysbiosis-in-the-infection-immune-network
#29
Donggeng Guo, Jinhan Lv, Xi Chen, Xiaoxu Yan, Fenglian Ma, Yuanyuan Liu, Xu Chen, Jing Xie, Mingzhu Zhang, Zheyu Jin, Lijun Cai, Xichun Sun, Dongsheng Niu, Dayue D Duan
OBJECTIVES: To characterize serum microRNA (miR) and the miR interactome of active RA patients in RA aetiology and pathogenesis. METHODS: The differentially expressed miRs (DEmiRs) in serum of naïve active RA patients (NARAPs, n = 9, into three pools) vs healthy controls (HCs, n = 15, into five pools) were identified with Agilent human miR microarray analysis. Candidate driver genes in epigenetic and pathogenic signalling pathway modules for RA were analysed using miRTarBase and a molecular complex detection algorithm...
September 10, 2020: Rheumatology
https://read.qxmd.com/read/32901294/serum-urate-is-related-to-subclinical-inflammation-in-asymptomatic-hyperuricaemia
#30
Desirée Luis-Rodríguez, Javier Donate-Correa, Ernesto Martín-Núñez, Carla Ferri, Víctor G Tagua, Atteneri Pérez Castro, Carmen Mora-Fernández, Juan F Navarro-González
OBJECTIVE: Asymptomatic hyperuricaemia (AHU) is associated with inflammatory disorders, including cardiovascular disease. Uric acid (UA) lowering therapies may reduce the risk of appearance or the progression of these comorbidities. In this work, we investigated the relationship between serum UA levels and inflammation in subjects with AHU. METHODS: Serum levels of high-sensitivity CRP (hsCRP), TNF-α and IL-6, and mRNA expression of TNFa and IL6 in peripheral blood mononuclear cells were measured in individuals with AHU and without comorbid conditions and in a control group with similar characteristics and normal serum UA levels...
September 9, 2020: Rheumatology
https://read.qxmd.com/read/32901293/highly-sensitive-serum-cardiac-troponin-t-and-cardiovascular-events-in-patients-with-systemic-lupus-erythematosus-tropoplus-study
#31
Julie Chezel, Nathalie Costedoat-Chalumeau, Cedric Laouénan, Diane Rouzaud, Camille Chenevier-Gobeaux, Véronique Le Guern, Alexis Mathian, Drifa Belhadi, Sébastien de Almeida Chaves, Pierre Duhaut, Olivier Fain, Lionel Galicier, Pascale Ghillani-Dalbin, Jean Emmanuel Kahn, Nathalie Morel, Laurent Perard, Micheline Pha, Fanny Saidoune, Francoise Sarrot-Reynauld, Olivier Aumaitre, François Chasset, Nicolas Limal, Helene Desmurs-Clavel, Felix Ackermann, Zahir Amoura, Thomas Papo, Karim Sacre
OBJECTIVE: Identification of biological markers able to better stratify cardiovascular risks in SLE patients is needed. We aimed to determine whether serum cardiac troponin T (cTnT) levels measured with a highly sensitive assay [high sensitivity cTnT (HS-cTnT)] may predict cardiovascular events (CVEs) in SLE. METHOD: All SLE patients included between 2007 and 2010 in the randomized, double-blind, placebo-controlled, multicentre PLUS trial were screened. Patients with no past history of CVE at inclusion and a follow-up period of >20 months were analysed...
September 9, 2020: Rheumatology
https://read.qxmd.com/read/32901286/acute-pancreatitis-an-atypical-presentation-of-granulomatosis-with-polyangiitis
#32
Swati Tyagi, Geet Bajpai
No abstract text is available yet for this article.
September 9, 2020: Rheumatology
https://read.qxmd.com/read/32901283/variation-in-the-pharmacokinetics-of-glucosamine-in-healthy-individuals
#33
Chhavi Asthana, Gregory M Peterson, Madhur D Shastri, Rahul P Patel
OBJECTIVES: Clinical trial data for the efficacy of glucosamine in OA are conflicting. Reportedly, Rotta-manufactured glucosamine products are more likely to be effective, and a possible explanation is greater bioavailability than other brands. Specifically, the aim was to compare the steady-state pharmacokinetics of Rotta- and non-Rotta-manufactured glucosamine products in healthy volunteers and examine the interindividual variability. METHODS: In a crossover design, healthy adult participants ingested 1500 mg/day of a Rotta (DONA powder sachets; imported by Mylan Health, Carole Park, QLD, Australia) and a non-Rotta (glucosamine sulphate 1500 mg one-a-day tablet; Blackmores, Warriewood, NSW, Australia) glucosamine product/brand individually for 6 days...
September 9, 2020: Rheumatology
https://read.qxmd.com/read/32901277/cervical-spine-involvement-in-ankylosing-spondylitis-mimicking-eagle-s-syndrome
#34
Sadettin Uslu
No abstract text is available yet for this article.
September 9, 2020: Rheumatology
https://read.qxmd.com/read/32901272/comment-on-diagnosis-of-giant-cell-arteritis-reply
#35
Cristina Ponte, Joana Martins-Martinho, Raashid Ahmed Luqmani
No abstract text is available yet for this article.
September 9, 2020: Rheumatology
https://read.qxmd.com/read/32901271/comment-on-diagnosis-of-giant-cell-arteritis
#36
Edsel B Ing
No abstract text is available yet for this article.
September 9, 2020: Rheumatology
https://read.qxmd.com/read/32901256/gastrointestinal-involvement-in-adult-iga-vasculitis
#37
Santos Castañeda, Esther F Vicente-Rabaneda, Ricardo Blanco, Miguel A González-Gay
No abstract text is available yet for this article.
September 9, 2020: Rheumatology
https://read.qxmd.com/read/32901253/iga-vasculitis-presenting-as-recurrent-hemopericardium
#38
Victoria Mank, Zhaohui Arter, Ki Eum, Salvatore Mignano, Sunghun Cho
No abstract text is available yet for this article.
September 9, 2020: Rheumatology
https://read.qxmd.com/read/32894294/prognosis-of-adult-idiopathic-inflammatory-myopathy-associated-interstitial-lung-disease-a-retrospective-study-of-679-adult-cases
#39
Shan Li, Yuxin Sun, Chi Shao, Hui Huang, Qian Wang, Kai Xu, Xin Zhang, Peng Liu, Xiaofeng Zeng, Zuojun Xu
OBJECTIVES: Few studies have investigated the prognostic factors for idiopathic inflammatory myopathy-associated interstitial lung disease (IIM-ILD) across different clinical/serological phenotypes. METHODS: We conducted a retrospective analysis of patients diagnosed with IIM between January 2012 and December 2017. RESULTS: Of the 760 IIM cases registered, 679 adult cases were included in this study. ILD was present in 508 cases, and the presence of ILD in the clinically amyopathic DM, DM and PM groups was 92...
September 7, 2020: Rheumatology
https://read.qxmd.com/read/32893307/wt1-gene-mutations-in-systemic-lupus-erythematosus-with-atypical-haemolytic-uremic-syndrome
#40
Chin-Fang Su, Hsien-Tzung Liao, Chang-Youh Tsai
No abstract text is available yet for this article.
September 7, 2020: Rheumatology
journal
journal
20237
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"