journal
https://read.qxmd.com/read/38048602/clavicle-fracture-in-sapho-syndrome
#21
JOURNAL ARTICLE
Yajing Xi, Zhimin Lin, Naigang Chen, Xiujuan Hou, Yuelan Zhu, Chen Li
No abstract text is available yet for this article.
December 4, 2023: Rheumatology
https://read.qxmd.com/read/38048600/comment-on-increased-risk-of-osteoporosis-and-femoral-neck-fractures-in-patients-with-familial-mediterranean-fever-a-large-retrospective-cohort-study
#22
JOURNAL ARTICLE
Kerem Parlar, Berkay Kilic, Serdal Ugurlu
No abstract text is available yet for this article.
December 4, 2023: Rheumatology
https://read.qxmd.com/read/38048595/factors-associated-with-treatment-intensification-in-patients-with-axial-spondyloarthritis-and-high-disease-activity-in-clinical-practice
#23
JOURNAL ARTICLE
Casper Webers, Rabab Nezam El-Din, Esther Beckers, Marin Been, Harald E Vonkeman, Astrid van Tubergen
OBJECTIVE: To investigate which factors are associated with treatment intensification (TI) in axial spondylarthritis (axSpA) patients with high disease activity (HDA). METHODS: Patients with axSpA and HDA (Ankylosing Spondylitis Disease Activity Score [ASDAS]≥2.1) from the Dutch SpA-Net registry were included. TI was defined as: 1) higher dose or shorter interval of the same drug, 2) switch from current drug to another due to inefficacy, or 3) addition of a new drug...
December 4, 2023: Rheumatology
https://read.qxmd.com/read/38039151/antibody-predictors-of-mortality-and-lung-function-trends-in-myositis-spectrum-interstitial-lung-disease
#24
JOURNAL ARTICLE
Jennifer R Hannah, Alexandra Lawrence, Jennifer Martinovic, Marium Naqvi, Felix Chua, Vasileios Kouranos, Saadia Sasha Ali, Carmel Stock, Cara Owens, Anand Devaraj, Louise Pollard, Sangita Agarwal, Belén Atienza-Mateo, Miguel Angel González-Gay, Amit Patel, Alex West, Kate Tinsley, Hasti Robbie, Boris Lams, Athol U Wells, Sam Norton, James Galloway, Elisabetta A Renzoni, Patrick A Gordon
OBJECTIVES: The impact of autoantibody profiles on prognosis of idiopathic inflammatory myositis associated interstitial lung disease (IIM-ILD) and myositis spectrum ILD with Myositis Specific Antibodies (MSA) remains unclear. This retrospective cohort study examines whether serological profiles are associated with mortality and longitudinal lung function change. METHODS: Baseline clinical/demographic characteristics and follow-up lung function of consecutive adult patients with IIM-ILD or Interstitial Pneumonia with Autoimmune Features (IPAF) positive for MSAs were extracted from three hospitals...
December 1, 2023: Rheumatology
https://read.qxmd.com/read/38019954/predicting-treatment-response-to-methotrexate-are-we-closer-to-solving-the-enigma
#25
JOURNAL ARTICLE
Elena Myasoedova
No abstract text is available yet for this article.
November 29, 2023: Rheumatology
https://read.qxmd.com/read/38019947/colchicine-the-good-the-bad-the-ugly-and-how-to-minimise-the-risks
#26
JOURNAL ARTICLE
Lisa K Stamp, Carl Horsley, Leanne Te Karu, Nicola Dalbeth, Murray Barclay
Colchicine has an important role in managing various conditions, including gout, familial Mediterranean fever, amyloidosis, Behcet's syndrome, recurrent pericarditis, and calcium pyrophosphate deposition disease. The adverse effect profile of colchicine is well understood. However, due to its narrow therapeutic index, colchicine has been associated with overdose and fatalities. When ingested in toxic amounts, the mainstay of management is supportive care. Strategies to minimise the risk of colchicine poisoning can focus on three broad causes: unauthorised access, intentional overdose, and inappropriate dosing...
November 29, 2023: Rheumatology
https://read.qxmd.com/read/38011669/an-international-multi-centre-analysis-of-current-prescribing-practices-and-shared-decision-making-in-psoriatic-arthritis
#27
JOURNAL ARTICLE
Lily Watson, Conor Coyle, Caroline Whately-Smith, Melanie Brooke, Uta Kiltz, Ennio Lubrano, Rubén Queiro, David Trigos, Jan Brandt-Juergens, Ernest Choy, Salvatore D'Angelo, Andrea Delle Sedie, Emmanuelle Dernis, Sandrine Guis, Philip Helliwell, Pauline Ho, Axel J Hueber, Beatriz Joven, Michaela Koehm, Carlos Montilla, Jon Packham, José Antonio Pinto Tasende, Felipe Julio Ramirez Garcia, Adeline Ruyssen-Witrand, Rossana Scrivo, Sarah Twigg, Martin Soubrier, Théo Wirth, Laure Gossec, Laura C Coates
OBJECTIVES: Shared decision-making (SDM) is advocated to improve patient outcomes in Psoriatic arthritis (PsA). We analysed current prescribing practices and the extent of SDM in PsA across Europe. METHODS: The ASSIST study was a cross-sectional observational study of PsA patients aged ≥18 years attending face-to-face appointments between July 2021-March 2022. Patient demographics, current treatment and treatment decisions were recorded. SDM was measured by the clinician's effort to collaborate (CollaboRATE questionnaire) and patient communication confidence (PEPPI-5 tool)...
November 27, 2023: Rheumatology
https://read.qxmd.com/read/38011668/real-world-efficacy-of-belimumab-in-systemic-lupus-erythematosus-a-prospective-cohort-from-a-single-center-in-china
#28
JOURNAL ARTICLE
Yin Zhao, Fumin Qi, Jinyu Bai, Na Zhang, Tong Yang, Wenwen Sun, Xin Li, Wei Wei
OBJECTIVES: To explore the efficacy and safety of belimumab among Chinese patients with systemic lupus erythematosus (SLE) in a real-world setting. METHODS: A prospective cohort study was performed, and SLE patients taking belimumab on a background of standard-of-care (SoC) treatment were consecutively enrolled from June 2021 to December 2022. Based on baseline characteristics, patients were divided into three groups: the newly diagnosed group, the relapsed group and the refractory group...
November 27, 2023: Rheumatology
https://read.qxmd.com/read/38006337/genetic-testing-of-beh%C3%A3-et-s-disease-using-next-generation-sequencing-to-identify-monogenic-mimics-and-hla-b-51
#29
JOURNAL ARTICLE
Alice Burleigh, Ebun Omoyinmi, Charalampia Papadopoulou, Eslam Al-Abadi, Ying Hong, Fiona Price-Kuehne, Elena Moraitis, Hannah Titheradge, Francesca Montesi, Diane Xu, Despina Eleftheriou, Paul Brogan
OBJECTIVE: Several monogenic autoinflammatory disorders and primary immunodeficiencies can present early in life with features that may be mistaken for Behçet's disease (BD). We aimed to develop a genetic analysis workflow to identify rare monogenic BD-like diseases and establish the contribution of HLA haplotype in a cohort of patients from the UK. METHODS: Patients with clinically suspected BD were recruited from four BD specialist care centres in the UK...
November 25, 2023: Rheumatology
https://read.qxmd.com/read/38006334/comment-on-fibromyalgia-remains-the-elephant-in-the-clinical-room
#30
JOURNAL ARTICLE
Frank McKenna
No abstract text is available yet for this article.
November 25, 2023: Rheumatology
https://read.qxmd.com/read/38001036/long-term-outcomes-of-lupus-nephritis-with-low-level-proteinuria-a-multicenter-retrospective-study
#31
JOURNAL ARTICLE
Takeshi Zoshima, Satoshi Hara, Kazuyuki Suzuki, Misaki Yoshida, Masahiro Konishi, Shinya Hibino, Takuya Suda, Ryohei Hoshiba, Hiroyuki Kawahara, Shigeto Horita, Hiromi Nuka, Ichiro Mizushima, Mitsuhiro Kawano
OBJECTIVES: Reportedly, patients with lupus nephritis (LN) and low-level proteinuria have favorable short-term renal outcomes. We aimed to clarify the long-term renal outcomes and overall survival of them, and the significance of renal biopsy in the early phase with low-level proteinuria. METHODS: We included 144 Japanese patients with biopsy-proven LN from ten hospitals. Low-level proteinuria was defined by a urine protein: creatinine ratio (UPCR) of ≤ 1 g/gCr based on previous reports...
November 24, 2023: Rheumatology
https://read.qxmd.com/read/38001025/multimorbidity-in-systemic-lupus-erythematosus-in-a-population-based-cohort-the-lupus-midwest-network
#32
JOURNAL ARTICLE
Gabriel Figueroa-Parra, Jose A Meade-Aguilar, Cassondra A Hulshizer, Tina M Gunderson, Alanna M Chamberlain, Uma Thanarajasingam, Kurt J Greenlund, Kamil E Barbour, Cynthia S Crowson, Alí Duarte-García
OBJECTIVES: To assess the prevalence and incidence of multimorbidity and the association with the SLICC/ACR damage index (SDI) among patients with systemic lupus erythematosus (SLE). METHODS: Using prevalent and incident population-based cohorts of patients with SLE and their matched comparators, we assessed 57 chronic conditions. Chronic conditions were categorized as SDI-related or SDI-unrelated. Multimorbidity was defined as the presence of 2+ chronic conditions...
November 24, 2023: Rheumatology
https://read.qxmd.com/read/37995294/characterization-of-digital-annular-pulleys-and-their-entheses-an-ultrasonographic-study-with-anatomical-and-histological-correlations
#33
JOURNAL ARTICLE
Luis Coronel, Peter Mandl, Maribel Miguel-Pérez, Joan Blasi, Maria Antonietta D'Agostino, Carlo Martinoli, David A Bong, Ingrid Möller
OBJECTIVES: Digital annular pulleys (DAP) are important anatomical structures for finger function. The anatomy, histology, and imaging assessment of DAP, particularly at the level of their entheses is still not clearly defined. The advent of high-frequency ultrasound (US) transducers opened new perspectives in evaluating sub-millimeter scale structures, such as pulleys, paving the way for their global assessment. The study aimed at characterizing DAP from an anatomical, histological, and US perspective, focusing on the detection and complete description of pulley entheses...
November 23, 2023: Rheumatology
https://read.qxmd.com/read/37995290/comment-on-the-diagnostic-value-of-sst2-for-myocardial-fibrosis-in-idiopathic-inflammatory-myopathies-in-subclinical-stage-of-cardiac-involvement
#34
JOURNAL ARTICLE
Lixi Zhang, Liying Peng, Shuang Zhou, Chanyuan Wu, Qian Wang, Mengtao Li
No abstract text is available yet for this article.
November 23, 2023: Rheumatology
https://read.qxmd.com/read/37995289/comment-on-the-diagnostic-value-of-sst2-for-myocardial-fibrosis-in-idiopathic-inflammatory-myopathies-in-subclinical-stage-of-cardiac-involvement-reply
#35
JOURNAL ARTICLE
Jianhong Sun, Geng Yin, Qibing Xie
No abstract text is available yet for this article.
November 23, 2023: Rheumatology
https://read.qxmd.com/read/37991871/effectiveness-of-biological-targeted-therapies-may-discriminate-seronegative-from-seropositive-rheumatoid-arthritis
#36
JOURNAL ARTICLE
Florenzo Iannone, Giuseppe Lopalco, Fabio Cacciapaglia, Vincenzo Venerito, Simone Perniola, Marco Fornaro
OBJECTIVE: To assess the real-world effectiveness of targeting biologic drugs (bDMARD) in rheumatoid arthritis (RA) patients negative for rheumatoid factor (RF) and anti-citrullinated protein antibodies (ACPA). METHODS: We retrospectively selected 81 seronegative and 404 seropositive RA patients receiving treatment with abatacept, anti-tumor necrosis factor (TNF) alpha, or tocilizumab. Effectiveness was evaluated by analyzing drug survival using Kaplan-Meyer analysis over 10-year follow-up...
November 22, 2023: Rheumatology
https://read.qxmd.com/read/37991850/validation-of-the-pediatric-beh%C3%A3-et-s-disease-classification-criteria-an-evidence-based-approach
#37
JOURNAL ARTICLE
Caterina Matucci-Cerinic, Palluy Helene, Al-Mayouf Sulaiman, Paul A Brogan, Luca Cantarini, Ahmet Gul, Ozgur Kasapcopur, Jasmin Kuemmerle-Deschner, Seza Ozen, David Saadoun, Farhad Shahram, Francesca Bovis, Mosci Eugenia, Nicolino Ruperto, Marco Gattorno, Isabelle Kone-Paut
OBJECTIVES: to validate the PEDiatric Behçet's Disease classification criteria (PEDBD) with an evidence-based approach. METHODS: 210 pediatric patients (70 Behçet's disease (BD), 40 Periodic Fever, Aphthous stomatitis, Pharyngitis, Adenitis, 35 familial Mediterranean fever, 26 hyper-IgD syndrome, 22 TNF-Receptor associated Periodic fever Syndrome, 17 undefined recurrent fevers) were randomly selected from the Eurofever Registry. A set of 11 experienced clinicians/researchers blinded to the original diagnosis evaluated the patients...
November 22, 2023: Rheumatology
https://read.qxmd.com/read/37988163/comparative-effectiveness-of-biological-disease-modifying-antirheumatic-drugs-and-janus-kinase-inhibitor-monotherapy-in-rheumatoid-arthritis
#38
JOURNAL ARTICLE
Akira Onishi, Hirotaka Yamada, Wataru Yamamoto, Ryu Watanabe, Ryota Hara, Masaki Katayama, Yasutaka Okita, Yuichi Maeda, Hideki Amuro, Yonsu Son, Ayaka Yoshikawa, Kenichiro Hata, Motomu Hashimoto, Jun Saegusa, Akio Morinobu
OBJECTIVES: To examine the effectiveness and drug tolerability of biological disease-modifying antirheumatic drugs (bDMARDs) and Janus kinase inhibitor (JAKi) monotherapy in patients with rheumatoid arthritis (RA) in a multicentre cohort study. METHODS: Patients with RA initiated with bDMARD/JAKi monotherapy without conventional synthetic DMARDs were included. Monotherapy regimens were categorised as interleukin-6 receptor inhibitors (IL-6Ri), cytotoxic T-lymphocyte-associated protein 4 immunoglobulin (CTLA4Ig), JAKi, or tumour necrosis factor inhibitors (TNFi)...
November 21, 2023: Rheumatology
https://read.qxmd.com/read/37982747/chimeric-antigen-receptor-t-cell-therapy-a-new-emerging-landscape-in-autoimmune-rheumatic-diseases
#39
JOURNAL ARTICLE
Xia Lyu, Latika Gupta, Eleni Tholouli, Hector Chinoy
Chimeric antigen receptor T cell (CAR-T) therapy, an innovative immune cell therapy, has revolutionised the treatment landscape of haematological malignancies. The past two years have witnessed the successful application of CD19-targeting CAR constructs in refractory cases of autoimmune rheumatic diseases, including systemic lupus erythematosus, systemic sclerosis, and anti-synthetase syndrome. In comparison to existing B cell depletion therapies, targeting CD19 has demonstrated a more rapid and profound therapeutic effect, enabling drug-free remission with manageable adverse events...
November 20, 2023: Rheumatology
https://read.qxmd.com/read/37982745/comparison-of-biologics-in-psoriatic-arthritis-an-important-clinical-issue
#40
JOURNAL ARTICLE
Laura Pina Vegas, Pascal Claudepierre
No abstract text is available yet for this article.
November 20, 2023: Rheumatology
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