journal

American Journal of Kidney Diseases

journal
https://read.qxmd.com/read/32220510/update-on-lupus-nephritis-core-curriculum-2020
#1
REVIEW
Samir V Parikh, Salem Almaani, Sergey Brodsky, Brad H Rovin
Systemic lupus erythematosus is a multisystem autoimmune disease that commonly affects the kidneys. Lupus nephritis (LN) is the most common cause of kidney injury in systemic lupus erythematosus and a major risk factor for morbidity and mortality. The pathophysiology of LN is heterogeneous. Genetic and environmental factors likely contribute to this heterogeneity. Despite improved understanding of the pathogenesis of LN, treatment advances have been few and risk for kidney failure remains unacceptably high...
March 24, 2020: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://read.qxmd.com/read/32220509/routine-kt-v-and-normalized-protein-nitrogen-appearance-rate-determined-from-conductivity-access-clearance-with-infrequent-postdialysis-serum-urea-nitrogen-measurements
#2
Jochen G Raimann, Xiaoling Ye, Peter Kotanko, John T Daugirdas
RATIONALE & OBJECTIVES: Conventional monitoring of hemodialysis dose is implemented using urea kinetic modeling based on single-pool Kt/V, which requires both pre- and postdialysis serum urea nitrogen (SUN) measurements. We compared this conventional approach to one in which Kt/V is calculated using conductivity clearance, thereby reducing the need for regular postdialysis SUN measurements. STUDY DESIGN: Comparative study of 2 diagnostic tests. SETTING & PARTICIPANTS: Prevalent patients receiving maintenance hemodialysis for at least 2 years for whom both urea reduction ratio (URR) and average conductivity clearance (Kecn) were measured...
March 24, 2020: American Journal of Kidney Diseases
https://read.qxmd.com/read/32217082/covid-19-and-dialysis-units-what-do-we-know-now-and-what-should-we-do
#3
EDITORIAL
T Alp Ikizler
No abstract text is available yet for this article.
March 21, 2020: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://read.qxmd.com/read/32199710/using-patient-experience-survey-data-to-improve-in-center-hemodialysis-care-a-practical-review
#4
REVIEW
Taimur Dad, Megan E Grobert, Michelle M Richardson
Patient experience is an integral aspect of the care we deliver to our dialysis patients. Standardized evaluation of patient experience with in-center hemodialysis started in the United States in 2012 with the In-Center Hemodialysis Consumer Assessment of Healthcare Providers and Systems (ICH CAHPS) survey. Over time there have been a few changes to this survey, how it is administered, and how it fits within the Centers for Medicare & Medicaid Services End-Stage Renal Disease Quality Incentive Program. Although the importance of this survey has been growing, knowledge of this survey among nephrologists has lagged...
March 19, 2020: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://read.qxmd.com/read/32199709/diagnosis-and-management-of-pulmonary-hypertension-in-patients-with-ckd
#5
REVIEW
Carl P Walther, Vijay Nambi, Nicola A Hanania, Sankar D Navaneethan
Pulmonary hypertension (PH) is a highly prevalent and important condition in adults with chronic kidney disease (CKD). In this review, we summarize the definition of PH, discuss its pathophysiology and classifications, and describe diagnostic and management strategies in patients with CKD, including those with kidney failure treated by kidney replacement therapy. In the general population, PH is classified into 5 groups based on clinical presentation, pathology, hemodynamics, and management strategies. In this classification system, PH in CKD is placed in a diverse group with unclear or multifactorial mechanisms, although underlying cardiovascular disease may account for most cases...
March 19, 2020: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://read.qxmd.com/read/32199708/efficacy-of-furosemide-oral-sodium-chloride-and-fluid-restriction-for-treatment-of-syndrome-of-inappropriate-antidiuresis-siad-an-open-label-randomized-controlled-study-the-effuse-fluid-trial
#6
Pajaree Krisanapan, Surachet Vongsanim, Pathomporn Pin-On, Chidchanok Ruengorn, Kajohnsak Noppakun
RATIONALE & OBJECTIVE: First-line therapy for syndrome of inappropriate antidiuresis (SIAD) is fluid restriction. Additional treatment for patients who do not respond to fluid restriction are water restriction with furosemide or water restriction with furosemide and salt supplementation. However, the efficacy of these treatments has never been tested in a randomized controlled study. The objective of this study was to investigate whether, combined with fluid restriction, furosemide with or without sodium chloride (NaCl) supplementation was more effective than fluid restriction alone in the treatment of hyponatremia in SIAD...
March 19, 2020: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://read.qxmd.com/read/32199707/the-role-of-the-general-nephrologist-in-evaluating-patients-for-kidney-transplantation-core-curriculum-2020
#7
REVIEW
Sarthak Virmani, William S Asch
Transplantation is the preferred modality of replacement therapy for most patients with kidney failure. In the United States, more than 3,000 new patients are registered each month on the kidney transplant waiting list for this life-saving therapy. A potential kidney transplant recipient's evaluation typically begins with a referral by the general nephrologist to a transplantation center. In this installment in the Core Curriculum in Nephrology, we endeavor to achieve a shared understanding of the patient factors that contribute to optimal patient and allograft outcomes following kidney transplantation...
March 19, 2020: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://read.qxmd.com/read/32197881/persistent-hematuria-and-kidney-disease-progression-in-iga-nephropathy-a-cohort-study
#8
Gui-Zhen Yu, Ling Guo, Jin-Feng Dong, Su-Fang Shi, Li-Jun Liu, Jin-Wei Wang, Gui-Li Sui, Xu-Jie Zhou, Ying Xing, Hai-Xia Li, Ji-Cheng Lv, Hong Zhang
RATIONALE & OBJECTIVE: Hematuria is the most typical presentation of immunoglobulin A nephropathy (IgAN); however, its role in disease progression is still controversial. This study aimed to evaluate the association of hematuria and progression of IgAN. STUDY DESIGN: Retrospective cohort study. SETTING & PARTICIPANTS: A cohort of 1,333 patients with IgAN treated at a Chinese referral hospital with a median follow-up of 45 months. PREDICTORS: Microhematuria was evaluated in fresh urine using a fully automated urine particle analyzer (automated method) and urine sediment examination by a skilled examiner (manual method)...
March 18, 2020: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://read.qxmd.com/read/32197883/in-reply-to-lung-ultrasound-in-hemodialysis-patients-is-it-practical-to-scan-28-zones
#9
LETTER
Charalampos Loutradis, Pantelis A Sarafidis, Carmine Zoccali
No abstract text is available yet for this article.
March 16, 2020: American Journal of Kidney Diseases
https://read.qxmd.com/read/32197882/lung-ultrasound-in-hemodialysis-patients-is-it-practical-to-scan-28-zones
#10
LETTER
Abhilash Koratala, Daniel W Ross
No abstract text is available yet for this article.
March 16, 2020: American Journal of Kidney Diseases
https://read.qxmd.com/read/32192786/interventions-for-preventing-bone-disease-in-kidney-transplant-recipients-editorial-summary-of-a-cochrane-review
#11
Suetonia C Palmer, Giovanni F M Strippoli
No abstract text is available yet for this article.
March 16, 2020: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://read.qxmd.com/read/32192785/erratum-regarding-evolution-of-echocardiographic-measures-of-cardiac-disease-from-ckd-to-esrd-and-risk-of-all-cause-mortality-findings-from-the-cric-study-am-j-kidney-dis-2018-72-3-390-399
#12
(no author information available yet)
No abstract text is available yet for this article.
March 16, 2020: American Journal of Kidney Diseases
https://read.qxmd.com/read/32192784/interventions-for-preventing-bone-disease-following-kidney-transplantation-is-there-evidence-for-specific-therapy
#13
Stuart M Sprague
No abstract text is available yet for this article.
March 16, 2020: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://read.qxmd.com/read/32173108/kidney-supportive-care-core-curriculum-2020
#14
REVIEW
Samantha L Gelfand, Jennifer S Scherer, Holly M Koncicki
Kidney supportive care is the application of palliative medicine principles and practices to patients with kidney disease. The goal is alleviation of suffering through treatment of symptoms, empathic communication, and support for psychosocial distress. Kidney supportive care includes primary palliative care provided by nephrology teams, as well as referral of patients with complex distress for comanagement by an interprofessional specialty palliative care team, when available. The team may include physicians, nurses, social workers, chaplains, and dieticians...
March 12, 2020: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://read.qxmd.com/read/32173107/multidisciplinary-medication-therapy-management-and-hospital-readmission-in-patients-undergoing-maintenance-dialysis-a-retrospective-cohort-study
#15
Harold J Manley, Gideon Aweh, Daniel E Weiner, Huan Jiang, Dana C Miskulin, Doug Johnson, Eduardo K Lacson
RATIONALE & OBJECTIVES: Dialysis patients frequently experience medication-related problems. We studied the association of a multidisciplinary medication therapy management (MTM) with 30-day readmission rates. STUDY DESIGN: Retrospective cohort study. SETTING & PARTICIPANTS: Maintenance dialysis patients discharged home from acute-care hospitals between May 2016 and April 2017 who returned to End-Stage Renal Disease Seamless Care Organization dialysis clinics after discharge were eligible...
March 12, 2020: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://read.qxmd.com/read/32171640/range-and-variability-of-outcomes-reported-in-randomized-trials-conducted-in-patients-with-polycystic-kidney-disease-a-systematic-review
#16
Bénédicte Sautenet, Yeoungjee Cho, Talia Gutman, Gopala Rangan, Albert Ong, Arlene B Chapman, Curie Ahn, Helen Coolican, Juliana Tze-Wah Kao, Kevin Fowler, Ron T Gansevoort, Claire Geneste, Ronald D Perrone, Tess Harris, Vicente E Torres, York Pei, Jonathan C Craig, Allison Tong
RATIONALE & OBJECTIVE: Trials in autosomal dominant polycystic kidney disease (ADPKD) have increased, but their impact on decision making has been limited. Because heterogeneity in reported outcomes may be responsible, we assessed their range and variability in ADPKD trials. STUDY DESIGN: Systematic review. SETTING & STUDY POPULATION: Adult participants in clinical trials in ADPKD. SELECTION CRITERIA FOR STUDIES: We included trials that studied adults and were published in English...
March 11, 2020: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://read.qxmd.com/read/32151430/risk-of-vascular-access-infection-associated-with-buttonhole-cannulation-of-fistulas-data-from-the-national-healthcare-safety-network
#17
Meghan Lyman, Duc B Nguyen, Alicia Shugart, Heidi Gruhler, Christi Lines, Priti R Patel
RATIONALE & OBJECTIVE: Compared with conventional (rope-ladder cannulation [RLC]) methods, use of buttonhole cannulation (BHC) to access arteriovenous fistulas (AVFs) may be associated with increased risk for bloodstream infection and other vascular access-related infection. We used national surveillance data to evaluate the infection burden and risk among in-center hemodialysis patients with AVFs using BHC. STUDY DESIGN: Descriptive analysis of infections and related events and retrospective observational cohort study using National Healthcare Safety Network (NHSN) surveillance data...
March 6, 2020: American Journal of Kidney Diseases
https://read.qxmd.com/read/32093980/phospholipase-a-2-receptor-antibody-positive-pregnancy-a-case-report
#18
Mala Sachdeva, Laurence H Beck, Ilene Miller, Vanessa Bijol, Steven Fishbane
Renal course and clinical outcomes in pregnant women with primary membranous nephropathy are not completely understood. In addition, the use of autoantibodies to M-type phospholipase A2 receptor (PLA2 R) as a serologic marker throughout pregnancy and postpartum in the mother and baby is not yet fully elucidated. We followed up a pregnant woman with primary membranous nephropathy during pregnancy and postpartum and describe the clinical course and outcomes of mother and baby and the course of PLA2 R antibody titers...
February 21, 2020: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://read.qxmd.com/read/32046863/endovascular-bypass-for-thoracic-vein-occlusion-an-innovative-technique-for-hemodialysis-vascular-access
#19
EDITORIAL
Tushar J Vachharajani, Lee Kirksey, Gordon McLennan
No abstract text is available yet for this article.
February 8, 2020: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://read.qxmd.com/read/32037098/aki-a-relevant-safety-end-point
#20
Ian E McCoy, Glenn M Chertow
Acute kidney injury (AKI) is a common outcome evaluated in clinical studies, often as a safety end point in a variety of cardiovascular, kidney disease, and other clinical trials. AKI end points that include modest increases in serum creatinine levels from baseline may not associate with patient-centered outcomes such as initiation of dialysis, sustained decline in kidney function, or death. Surprisingly, data from several randomized controlled trials have suggested that in certain settings, the development of AKI may be associated with favorable outcomes...
February 6, 2020: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
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