journal
https://read.qxmd.com/read/36949623/factors-associated-with-discontinuation-of-tuberculosis-preventive-treatment-post-hoc-analysis-of-two-randomized-controlled-trials
#1
JOURNAL ARTICLE
Alex Allard-Gray, Isaac Boakye, Alioune Camara, Lisa Eisenbeis, Eleny Guimarães-Teixeira, Oumou Sow, David Zielinski, Jonathon R Campbell, Dick Menzies
BACKGROUND: Adherence to tuberculosis preventive treatment (TPT) is an important determinant of clinical benefit. We assessed the association of participant behaviors early in TPT with subsequent discontinuation. METHODS: We used data from a phase 3 randomized trial, and preceding phase 2 trial, comparing four-months rifampin to nine-months isoniazid for TPT. We excluded participants whose providers discontinued TPT due to adverse events or tuberculosis disease...
March 23, 2023: Clinical Infectious Diseases
https://read.qxmd.com/read/36949619/vaccination-of-older-adults-against-rsv-the-final-pieces-of-the-puzzle
#2
JOURNAL ARTICLE
Katherine E Atkins, David Hodgson
No abstract text is available yet for this article.
March 23, 2023: Clinical Infectious Diseases
https://read.qxmd.com/read/36949605/modeling-respiratory-syncytial-virus-adult-vaccination-in-the-united-states-with-a-dynamic-transmission-model
#3
JOURNAL ARTICLE
T Van Effelterre, N Hens, L J White, S Gravenstein, A R Bastian, N Buyukkaramikli, C-Y Cheng, J Hartnett, G Krishnarajah, K Weber, L Hernandez Pastor
BACKGROUND: Respiratory syncytial virus (RSV) is shown to cause substantial morbidity, hospitalization, and mortality in infants and older adults. Population-level modelling of RSV would allow for estimation of the full burden of disease and the potential epidemiological impact of novel prophylactics. METHODS: We model the epidemiology of RSV in the US across all ages using a deterministic compartmental transmission model. Population-level symptomatic RSV acute respiratory tract infection (ARI) cases were projected across different natural history scenarios, both with and without vaccination of older adults aged ≥ 60...
March 23, 2023: Clinical Infectious Diseases
https://read.qxmd.com/read/36949581/applying-door-endpoint-to-randomized-trial-of-sulopenem-for-the-treatment-of-complicated-urinary-tract-infections
#4
JOURNAL ARTICLE
Michael W Dunne, Steven I Aronin, Anita F Das, Jayanti Gupta, Karthik Akinapelli, Jeanne Breen, Michael T Zelasky, Sailaja Puttagunta
No abstract text is available yet for this article.
March 23, 2023: Clinical Infectious Diseases
https://read.qxmd.com/read/36947143/programmatic-effectiveness-of-a-pediatric-typhoid-conjugate-vaccine-campaign-in-navi-mumbai-india
#5
JOURNAL ARTICLE
Seth A Hoffman, Christopher LeBoa, Kashmira Date, Pradeep Haldar, Pauline Harvey, Rahul Shimpi, Qian An, Chenhua Zhang, Niniya Jayaprasad, Lily Horng, Kirsten Fagerli, Priyanka Borhade, Debjit Chakraborty, Sunil Bahl, Arun Katkar, Abhishek Kunwar, Vijay Yewale, Jason R Andrews, Pankaj Bhatnagar, Shanta Dutta, Stephen P Luby
BACKGROUND: The WHO recommends vaccines for prevention and control of typhoid fever, especially where antimicrobial-resistant typhoid circulates. In 2018 the Navi Mumbai Municipal Corporation (NMMC), implemented a TCV campaign. The campaign targeted all children aged 9-months through 14-years within NMMC boundaries (∼320,000 children) over 2 vaccination phases. The phase 1 campaign occurred from July 14-August 25, 2018 (71% coverage, ∼113,420 children). We evaluated the phase 1 campaign's programmatic effectiveness in reducing typhoid cases at the community level...
March 22, 2023: Clinical Infectious Diseases
https://read.qxmd.com/read/36947142/isolation-and-quarantine-for-covid-19-in-the-united-states-2020-2022
#6
JOURNAL ARTICLE
John E Oeltmann, Divya Vohra, Holly H Matulewicz, Nickolas DeLuca, Jonathan P Smith, Chandra Couzens, R Ryan Lash, Barrington Harvey, Melissa Boyette, Alicia Edwards, Philip M Talboy, Odessa Dubose, Paul Regan, Penny Loosier, Elise Caruso, Dolores J Katz, Melanie M Taylor, Patrick K Moonan
BACKGROUND: Public health programs varied in ability to reach people with COVID-19 and their contacts to encourage separation from others. For both adult cases of COVID-19 and contacts, we estimated the impact of contact tracing activities on separation behaviors from January, 2020 until March, 2022. METHODS: We used a probability-based panel survey of a nationally representative sample to gather data for estimates and comparisons. RESULTS: An estimated 64,255,351 adults reported a positive SARS-CoV-2 test result; 79...
March 22, 2023: Clinical Infectious Diseases
https://read.qxmd.com/read/36947131/attainment-of-target-antibiotic-levels-by-oral-treatment-of-left-sided-infective-endocarditis-a-poet-substudy
#7
JOURNAL ARTICLE
Magnus Bock, Anna Marie Theut, Johan G C van Hasselt, Hengzhuang Wang, Kurt Fuursted, Niels Høiby, Christian Johann Lerche, Nikolaj Ihlemann, Sabine Gill, Ulrik Christiansen, Hans Linde Nielsen, Lars Lemming, Hanne Elming, Jonas A Povlsen, Niels Eske Bruun, Dan Høfsten, Emil L Fosbøl, Lars Køber, Martin Schultz, Mia M Pries-Heje, Jonas Henrik Kristensen, Jens Jørgen Christensen, Flemming S Rosenvinge, Christian Torp Pedersen, Jannik Helweg-Larsen, Niels Tønder, Kasper Iversen, Henning Bundgaard, Claus Moser
BACKGROUND: In the POET (Partial Oral Endocarditis Treatment) trial, oral step-down therapy was noninferior to full-length intravenous antibiotic administration. The aim of the present study was to perform pharmacokinetic/pharmacodynamic analyses for oral treatments of infective endocarditis to assess the probabilities of target attainment (PTAs). METHODS: Plasma concentrations of oral antibiotics were measured at day 1 and 5. Minimal inhibitory concentrations (MICs) were determined for the bacteria causing infective endocarditis (streptococci, staphylococci, or enterococci)...
March 22, 2023: Clinical Infectious Diseases
https://read.qxmd.com/read/36947122/gateway-to-typhoid-conjugate-vaccine-introduction-in-india-and-beyond-programmatic-effectiveness-of-a-public-sector-typhoid-conjugate-vaccine-campaign-in-navi-mumbai
#8
JOURNAL ARTICLE
https://read.qxmd.com/read/36942560/infectious-complications-of-lung-transplant-for-covid-associated-lung-injury-cali-a-single-center-case-control-cohort-study
#9
JOURNAL ARTICLE
Rebecca Osborn, Maha Alamri, Rade Tomic, Michael G Ison
BACKGROUND: Lung transplantation is one of the only options for patients with severe COVID-19-associated lung injury (CALI). Studies on patients who received a lung transplant for CALI have, to date, not looked at the infectious outcomes. METHODS: After IRB approval, a retrospective case-control cohort study, matched 1:1, collected data on patients who underwent lung transplantation for CALI (case) and for non-COVID-19 end-stage lung disease (control) between June 1, 2020 and April 1, 2022 at a large academic hospital in Chicago...
March 21, 2023: Clinical Infectious Diseases
https://read.qxmd.com/read/36942534/evaluating-the-impact-of-statin-use-on-influenza-vaccine-effectiveness-and-influenza-infection-in-older-adults
#10
JOURNAL ARTICLE
Hannah Chung, Michael A Campitelli, Sarah A Buchan, Aaron Campigotto, Branson Chen, Natasha S Crowcroft, Vinita Dubey, Jonathan B Gubbay, Timothy Karnauchow, Kevin Katz, Allison J McGeer, J Dayre McNally, Samira Mubareka, Michelle Murti, David C Richardson, Laura C Rosella, Kevin L Schwartz, Marek Smieja, George Zahariadis, Jeffrey C Kwong
BACKGROUND: Older adults are recommended to receive influenza vaccination annually and many use statins. Statins have immunomodulatory properties that might modify influenza vaccine effectiveness (VE) and alter influenza infection risk. METHODS: Using the test-negative design and linked laboratory and health administrative databases in Ontario, Canada, we estimated VE against laboratory-confirmed influenza among community-dwelling statin users and non-users aged ≥66 years during the 2010-2011 to 2018-2019 influenza seasons...
March 21, 2023: Clinical Infectious Diseases
https://read.qxmd.com/read/36942525/complexity-interactions-between-nirmatrelvir-ritonavir-and-voriconazole-in-patients-with-coronavirus-disease-2019
#11
JOURNAL ARTICLE
Peile Wang, Han Xing, Xiaojian Zhang, Jing Yang
No abstract text is available yet for this article.
March 21, 2023: Clinical Infectious Diseases
https://read.qxmd.com/read/36932686/correction-to-the-staphylococcus-aureus-network-adaptive-platform-trial-protocol-new-tools-for-an-old-foe
#12
(no author information available yet)
No abstract text is available yet for this article.
March 18, 2023: Clinical Infectious Diseases
https://read.qxmd.com/read/36932040/beta-lactam-therapeutic-drug-monitoring-tdm-in-critically-ill-patients
#13
JOURNAL ARTICLE
Teagan Zeggil, Bruce Dalton
No abstract text is available yet for this article.
March 18, 2023: Clinical Infectious Diseases
https://read.qxmd.com/read/36929831/reply-to-mori-et-al
#14
JOURNAL ARTICLE
Khaoula Bel Haj Ali, Adel Sekma, Yosra Mhalla, Asma Zorgati, Semir Nouira
No abstract text is available yet for this article.
March 17, 2023: Clinical Infectious Diseases
https://read.qxmd.com/read/36929823/the-who-what-when-and-where-of-inpatient-direct-oral-penicillin-challenge-implications-for-health-services-implementation
#15
JOURNAL ARTICLE
J A Trubiano, S Vogrin, E Mitri, R Hall, A Copaescu, J Waldron, J De Luca, M Rose, G Mackay, B Lambros, A P Douglas, N E Holmes, K Y L Chua
Inpatient direct oral challenge programs are increasingly deployed as part of antimicrobial stewardship (AMS) initiatives to reduce the burden and impacts of penicillin allergy labels on antibiotic prescribing. Using data from a prospective multicentre cohort inpatient penicillin allergy program, we identify the key targets for delabeling to aid health service implementation.
March 17, 2023: Clinical Infectious Diseases
https://read.qxmd.com/read/36929815/serum-ubiquitin-c-terminal-hydrolase-l1-glial-fibrillary-acidic-protein-and-neurofilament-light-chain-are-good-entry-points-and-biomarker-candidates-for-neurosyphilis-diagnosis-among-patients-without-hiv-to-avoid-lumbar-puncture
#16
JOURNAL ARTICLE
Lin Xie, Wei Li, Wei-Ming Ye, Yao Xiao, Wu-Jian Ke, Jian-Jun Niu, Tian-Ci Yang
BACKGROUND: Laboratory tests to diagnose neurosyphilis using cerebrospinal fluid (CSF) are currently disadvantageous as a lumbar puncture is required, which may result in patients with neurosyphilis missing an opportunity for early diagnosis. Thus, blood biomarker candidates that are more convenient and minimally invasive to collect for diagnosing neurosyphilis is urgently needed. METHODS: This observational study aimed to analyze serum ubiquitin C-terminal hydrolase-L1 (UCH-L1), glial fibrillary acidic protein (GFAP), and neurofilament light chain (NF-L) levels in 153 patients without HIV and to evaluate their diagnostic performance in neurosyphilis compared with CSF...
March 17, 2023: Clinical Infectious Diseases
https://read.qxmd.com/read/36928936/implementing-de-labeling-of-beta-lactam-allergies-getting-to-the-why
#17
JOURNAL ARTICLE
Bruce M Jones, Christopher M Bland
No abstract text is available yet for this article.
March 17, 2023: Clinical Infectious Diseases
https://read.qxmd.com/read/36928492/appropriate-outcome-settings-for-the-effectiveness-of-oral-zinc-treatment-for-coronavirus-disease-2019
#18
JOURNAL ARTICLE
Nobuaki Mori, Jun Hirai, Nobuhiro Asai, Hiroshige Mikamo
No abstract text is available yet for this article.
March 17, 2023: Clinical Infectious Diseases
https://read.qxmd.com/read/36921069/correction-to-the-lanzhou-brucella-leak-the-largest-laboratory-accident-in-the-history-of-infectious-diseases
#19
(no author information available yet)
No abstract text is available yet for this article.
March 15, 2023: Clinical Infectious Diseases
https://read.qxmd.com/read/36921068/correction-to-single-dose-mrna-vaccine-effectiveness-against-severe-acute-respiratory-syndrome-coronavirus-2-sars-cov-2-including-alpha-and-gamma-variants-a-test-negative-design-in-adults-70-years-and-older-in-british-columbia-canada
#20
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