Pure red cell aplasia of pregnancy: a distinct clinical entity

R I Baker, A Manoharan, E de Luca, C G Begley
British Journal of Haematology 1993, 85 (3): 619-22
We describe a 31-year-old patient with pure red cell aplasia of pregnancy, successfully managed with regular blood transfusions. In vitro studies showed specific inhibition of day 14 erythroid colonies (BFU-E) using serum and purified immunoglobulin G (IgG) obtained from the patient at diagnosis (before blood transfusion). The inhibition of BFU-E disappeared when haematological remission occurred 3 weeks after delivery and she remains clinically well with a normal haemoglobin 4 years later.

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