journal
https://read.qxmd.com/read/33448291/the-year-in-cardiovascular-medicine-2020-interventional-cardiology
#1
Fernando Alfonso, Nieves Gonzalo, Fernando Rivero, Javier Escaned
No abstract text is available yet for this article.
January 15, 2021: European Heart Journal
https://read.qxmd.com/read/33448289/c-reactive-protein-and-clinical-outcomes-in-patients-with-covid-19
#2
Nathaniel R Smilowitz, Dennis Kunichoff, Michael Garshick, Binita Shah, Michael Pillinger, Judith S Hochman, Jeffrey S Berger
BACKGROUND: A systemic inflammatory response is observed in coronavirus disease 2019 (COVID-19). Elevated serum levels of C-reactive protein (CRP), a marker of systemic inflammation, are associated with severe disease in bacterial or viral infections. We aimed to explore associations between CRP concentration at initial hospital presentation and clinical outcomes in patients with COVID-19. METHODS AND RESULTS: Consecutive adults aged ≥18 years with COVID-19 admitted to a large New York healthcare system between 1 March and 8 April 2020 were identified...
January 15, 2021: European Heart Journal
https://read.qxmd.com/read/33447845/heart-failure-drug-treatment-the-fantastic-four
#3
Johann Bauersachs
No abstract text is available yet for this article.
January 14, 2021: European Heart Journal
https://read.qxmd.com/read/33444429/illuminating-the-path-from-genetics-to-clinical-outcome-in-brugada-syndrome
#4
Pieter G Postema, Roddy Walsh, Connie R Bezzina
No abstract text is available yet for this article.
January 13, 2021: European Heart Journal
https://read.qxmd.com/read/33438022/alcohol-consumption-cardiac-biomarkers-and-risk-of-atrial-fibrillation-and-adverse-outcomes
#5
Dora Csengeri, Ngoc-Anh Sprünker, Augusto Di Castelnuovo, Teemu Niiranen, Julie Kk Vishram-Nielsen, Simona Costanzo, Stefan Söderberg, Steen M Jensen, Erkki Vartiainen, Maria Benedetta Donati, Christina Magnussen, Stephan Camen, Francesco Gianfagna, Maja-Lisa Løchen, Frank Kee, Jukka Kontto, Ellisiv B Mathiesen, Wolfgang Koenig, Blankenberg Stefan, Giovanni de Gaetano, Torben Jørgensen, Kari Kuulasmaa, Tanja Zeller, Veikko Salomaa, Licia Iacoviello, Renate B Schnabel
AIMS : There is inconsistent evidence on the relation of alcohol intake with incident atrial fibrillation (AF), in particular at lower doses. We assessed the association between alcohol consumption, biomarkers, and incident AF across the spectrum of alcohol intake in European cohorts. METHODS AND RESULTS : In a community-based pooled cohort, we followed 107 845 individuals for the association between alcohol consumption, including types of alcohol and drinking patterns, and incident AF...
January 13, 2021: European Heart Journal
https://read.qxmd.com/read/33438004/alcohol-consumption-atrial-fibrillation-and-cardiovascular-disease-finding-the-right-balance
#6
Jorge A Wong, David Conen
No abstract text is available yet for this article.
January 13, 2021: European Heart Journal
https://read.qxmd.com/read/33437997/lipoprotein-a-ldl-cholesterol-and-hypertension-predictors-of-the-need-for-aortic-valve-replacement-in-familial-hypercholesterolaemia
#7
Leopoldo Pérez de Isla, Gerald F Watts, Rodrigo Alonso, José Luis Díaz-Díaz, Ovidio Muñiz-Grijalvo, Daniel Zambón, Francisco Fuentes, Raimundo de Andrés, Teresa Padró, José López-Miranda, Pedro Mata
AIMS: Familial hypercholesterolaemia (FH) and elevated lipoprotein(a) [Lp(a)] are inherited disorders associated with premature atherosclerotic cardiovascular disease (ASCVD). Aortic valve stenosis (AVS) is the most prevalent valvular heart disease and low-density lipoprotein cholesterol (LDL-C) and Lp(a) may be involved in its pathobiology. We investigated the frequency and predictors of severe AVS requiring aortic valve replacement (AVR) in molecularly defined patients with FH. METHODS AND RESULTS: SAFEHEART is a long-term prospective cohort study of a population with FH and non-affected relatives (NAR)...
January 12, 2021: European Heart Journal
https://read.qxmd.com/read/33428721/a-leucopoietic-arterial-axis-underlying-the-link-between-ambient-air-pollution-and-cardiovascular-disease-in-humans
#8
Shady Abohashem, Michael T Osborne, Tawseef Dar, Nicki Naddaf, Taimur Abbasi, Ahmed Ghoneem, Azar Radfar, Tomas Patrich, Blake Oberfeld, Brian Tung, Zahi A Fayad, Sanjay Rajagopalan, Ahmed Tawakol
AIMS : Air pollution [i.e. particulate matter with diameter <2.5 μm (PM2.5)] is a risk factor for major adverse cardiovascular events (MACE). While PM2.5 promotes leucopoiesis and atherosclerotic inflammation in experimental models, it is unknown whether this occurs in humans. We tested in humans (a) whether PM2.5 associates with higher leucopoietic tissue activity and arterial inflammation (ArtI), (ii) whether these associations persist after accounting for the effects of potential confounders including socioeconomics, traffic noise, and risk factors, and (iii) whether these tissue effects mediate the association between air pollution and MACE...
January 11, 2021: European Heart Journal
https://read.qxmd.com/read/33428713/risk-stratification-in-brugada-syndrome-the-challenge-of-the-grey-zone
#9
Pietro Delise
No abstract text is available yet for this article.
January 11, 2021: European Heart Journal
https://read.qxmd.com/read/33428708/learning-whether-to-subtract-beta-blockers-it-s-about-time
#10
Sean van Diepen, Paul W Armstrong
No abstract text is available yet for this article.
January 11, 2021: European Heart Journal
https://read.qxmd.com/read/33428707/effect-of-long-term-beta-blocker-treatment-following-myocardial-infarction-among-stable-optimally-treated-patients-without-heart-failure-in-the-reperfusion-era-a-danish-nationwide-cohort-study
#11
Anders Holt, Paul Blanche, Bochra Zareini, Deepthi Rajan, Mohammed El-Sheikh, Anne-Marie Schjerning, Morten Schou, Christian Torp-Pedersen, Patricia McGettigan, Gunnar H Gislason, Morten Lamberts
 : Listen to the audio abstract of this contribution at https://doi.org/10.1093/eurheartj/ehaa1058. AIMS: We aimed to investigate the long-term cardio-protective effect associated with beta-blocker (BB) treatment in stable, optimally treated myocardial infarction (MI) patients without heart failure (HF). METHODS AND RESULTS: Using nationwide registries, we included patients with first-time MI undergoing coronary angiography (CAG) or percutaneous coronary intervention (PCI) during admission and treated with both acetyl-salicylic acid and statins post-discharge between 2003 and 2018...
January 11, 2021: European Heart Journal
https://read.qxmd.com/read/33421053/immune-cell-based-cardiovascular-risk-assessment-spotlight-on-the-neutrophil-lymphocyte-ratio
#12
Hendrik B Sager, Wolfgang Koenig
No abstract text is available yet for this article.
January 9, 2021: European Heart Journal
https://read.qxmd.com/read/33421051/brugada-syndrome-and-reduced-right-ventricular-outflow-tract-conduction-reserve-a-final-common-pathway
#13
Elijah R Behr, Yael Ben-Haim, Michael J Ackerman, Andrew D Krahn, Arthur A M Wilde
Brugada syndrome (BrS) was first described as a primary electrical disorder predisposing to the risk of sudden cardiac death and characterized by right precordial lead ST elevation. Early description of right ventricular structural abnormalities and of right ventricular outflow tract (RVOT) conduction delay in BrS patients set the stage for the current controversy over the pathophysiology underlying the syndrome: channelopathy or cardiomyopathy; repolarization or depolarization. This review examines the current understanding of the BrS substrate, its genetic and non-genetic basis, theories of pathophysiology, and the clinical implications thereof...
January 9, 2021: European Heart Journal
https://read.qxmd.com/read/33420498/empagliflozin-and-health-related-quality-of-life-outcomes-in-patients-with-heart-failure-with-reduced-ejection-fraction-the-emperor-reduced-trial
#14
Javed Butler, Stefan D Anker, Gerasimos Filippatos, Muhammad Shahzeb Khan, João Pedro Ferreira, Stuart J Pocock, Nadia Giannetti, James L Januzzi, Ileana L Piña, Carolyn S P Lam, Piotr Ponikowski, Naveed Sattar, Subodh Verma, Martina Brueckmann, Waheed Jamal, Ola Vedin, Barbara Peil, Cordula Zeller, Faiez Zannad, Milton Packer
AIMS: In this secondary analysis of the EMPEROR-Reduced trial, we sought to evaluate whether the benefits of empagliflozin varied by baseline health status and how empagliflozin impacted patient-reported outcomes in patients with heart failure with reduced ejection fraction. METHODS AND RESULTS: Health status was assessed by the Kansas City Cardiomyopathy Questionnaires-clinical summary score (KCCQ-CSS). The influence of baseline KCCQ-CSS (analyzed by tertiles) on the effect of empagliflozin on major outcomes was examined using Cox proportional hazards models...
January 9, 2021: European Heart Journal
https://read.qxmd.com/read/33417694/professor-anthony-h-gershlick
#15
Gerry P McCann, Nick P Curzen, Simon G Ray, Nilesh J Samani
No abstract text is available yet for this article.
January 8, 2021: European Heart Journal
https://read.qxmd.com/read/33417692/predicted-benefit-of-an-implantable-cardioverter-defibrillator-the-madit-icd-benefit-score
#16
Arwa Younis, Jeffrey J Goldberger, Valentina Kutyifa, Wojciech Zareba, Bronislava Polonsky, Helmut Klein, Mehmet K Aktas, David Huang, James Daubert, Mark Estes, David Cannom, Scott McNitt, Kenneth Stein, Ilan Goldenberg
AIMS: The benefit of prophylactic implantable cardioverter-defibrillator (ICD) is not uniform due to differences in the risk of life-threatening ventricular tachycardia (VT)/ventricular fibrillation (VF) and non-arrhythmic mortality. We aimed to develop an ICD benefit prediction score that integrates the competing risks. METHODS AND RESULTS: The study population comprised all 4531 patients enrolled in the MADIT trials. Best-subsets Fine and Gray regression analysis was used to develop prognostic models for VT (≥200 b...
January 8, 2021: European Heart Journal
https://read.qxmd.com/read/33417682/the-neutrophil-lymphocyte-ratio-and-incident-atherosclerotic-events-analyses-from-five-contemporary-randomized-trials
#17
Nicholas H Adamstein, Jean G MacFadyen, Lynda M Rose, Robert J Glynn, Amit K Dey, Peter Libby, Ira A Tabas, Nehal N Mehta, Paul M Ridker
AIMS: The neutrophil-lymphocyte ratio (NLR) is a readily available inflammatory biomarker that may associate with atherosclerosis and predict cardiovascular (CV) events. The aims of this study are to determine whether the NLR predicts incident major adverse cardiovascular events (MACE) and is modified by anti-inflammatory therapy. METHODS AND RESULTS: Baseline and on-treatment NLRs were calculated from complete blood counts among 60 087 participants randomized in the CANTOS, JUPITER, SPIRE-1, SPIRE-2, and CIRT trials to receive placebo or canakinumab, rosuvastatin, bococizumab, or methotrexate, respectively, and followed up for MACE...
January 8, 2021: European Heart Journal
https://read.qxmd.com/read/33411926/the-new-european-heart-journal-digital-health-and-innovations-team
#18
Panos Vardas, Folkert Asselbergs, Marteen van Smeden
No abstract text is available yet for this article.
January 7, 2021: European Heart Journal
https://read.qxmd.com/read/33411919/dietary-sodium-and-mortality-how-much-do-we-really-know
#19
Demilade A Adedinsewo, Amy W Pollak, Rickey E Carter
No abstract text is available yet for this article.
January 7, 2021: European Heart Journal
https://read.qxmd.com/read/33411883/at-the-heart-of-hospital-universitario-central-de-asturias-huca-oviedo-spain
#20
Isaac Pascual, Pablo Avanzas, César Morís
No abstract text is available yet for this article.
January 7, 2021: European Heart Journal
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