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European Heart Journal

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https://read.qxmd.com/read/30875424/atrial-fibrillation-ablation-in-practice-assessing-cabana-generalizability
#1
Peter A Noseworthy, Bernard J Gersh, David M Kent, Jonathan P Piccini, Douglas L Packer, Nilay D Shah, Xiaoxi Yao
AIMS: The Catheter Ablation vs. Antiarrhythmic Drug Therapy for Atrial Fibrillation (CABANA) trial aimed to assess the impact of ablation on morbidity and mortality. This observational study was conducted in parallel to CABANA to assess trial generalizability. METHODS AND RESULTS: Using a large US administrative database, we identified 183 760 patients with atrial fibrillation (AF) treated with ablation or medical therapy (antiarrhythmic or rate control drugs) between 1 August 2009 and 30 April 2016 (CABANA enrolment period)...
March 15, 2019: European Heart Journal
https://read.qxmd.com/read/30875420/left-atrial-ablation-for-management-of-atrial-fibrillation-cabana-vs-real-world-data-apples-and-oranges
#2
A John Camm
No abstract text is available yet for this article.
March 15, 2019: European Heart Journal
https://read.qxmd.com/read/30874770/concerning-the-degradation-of-%C3%AE-blocker-use-in-the-2018-esc-esh-hypertension-guidelines
#3
Alberto Morales-Salinas, Richard Kones
No abstract text is available yet for this article.
March 14, 2019: European Heart Journal
https://read.qxmd.com/read/30863865/elevated-high-density-lipoprotein-in-adolescents-with-type-1-diabetes-is-associated-with-endothelial-dysfunction-in-the-presence-of-systemic-inflammation
#4
Scott T Chiesa, Marietta Charakida, Eve McLoughlin, Helen C Nguyen, Georgios Georgiopoulos, Laura Motran, Yesmino Elia, M Loredana Marcovecchio, David B Dunger, R Neil Dalton, Denis Daneman, Etienne Sochett, Farid H Mahmud, John E Deanfield
AIMS: High-density lipoprotein (HDL) function may be altered in patients with chronic disease, transforming the particle from a beneficial vasoprotective molecule to a noxious pro-inflammatory equivalent. Adolescents with Type 1 diabetes often have elevated HDL, but its vasoprotective properties and relationship to endothelial function have not been assessed. METHODS AND RESULTS: Seventy adolescents with Type 1 diabetes (age 10-17 years) and 30 age-matched healthy controls supplied urine samples for the measurement of early renal dysfunction (albumin:creatinine ratio; ACR), blood samples for the assessment of cardiovascular risk factors (lipid profiles, HDL functionality, glycaemic control, and inflammatory risk score), and had their conduit artery endothelial function tested using flow-mediated dilation (FMD)...
March 12, 2019: European Heart Journal
https://read.qxmd.com/read/30863860/big-data-analytics-in-adult-congenital-heart-disease-why-coding-matters
#5
Folkert W Asselbergs, Folkert J Meijboom
No abstract text is available yet for this article.
March 12, 2019: European Heart Journal
https://read.qxmd.com/read/30863857/corrigendum
#6
(no author information available yet)
No abstract text is available yet for this article.
March 12, 2019: European Heart Journal
https://read.qxmd.com/read/30863854/quadriceps-tendon-rupture-in-wild-type-transthyretin-amyloidosis-attrwt
#7
Gonzalo Barge-Caballero, Paula López-Bargiela, Jorge Pombo-Otero, Patricia Pardo-Martínez
No abstract text is available yet for this article.
March 12, 2019: European Heart Journal
https://read.qxmd.com/read/30863853/uncommon-cause-of-progressive-dyspnoea-12-years-after-coronary-artery-bypass-surgery
#8
Felix Grabher, Wolfgang Hamm, Steffen Massberg, Martin Orban
No abstract text is available yet for this article.
March 12, 2019: European Heart Journal
https://read.qxmd.com/read/30860255/cardiovascular-disease-burden-from-ambient-air-pollution-in-europe-reassessed-using-novel-hazard-ratio-functions
#9
Jos Lelieveld, Klaus Klingmüller, Andrea Pozzer, Ulrich Pöschl, Mohammed Fnais, Andreas Daiber, Thomas Münzel
AIMS: Ambient air pollution is a major health risk, leading to respiratory and cardiovascular mortality. A recent Global Exposure Mortality Model, based on an unmatched number of cohort studies in many countries, provides new hazard ratio functions, calling for re-evaluation of the disease burden. Accordingly, we estimated excess cardiovascular mortality attributed to air pollution in Europe. METHODS AND RESULTS: The new hazard ratio functions have been combined with ambient air pollution exposure data to estimate the impacts in Europe and the 28 countries of the European Union (EU-28)...
March 12, 2019: European Heart Journal
https://read.qxmd.com/read/30859228/neuropeptide-y-causes-coronary-microvascular-constriction-and-is-associated-with-reduced-ejection-fraction-following-st-elevation-myocardial-infarction
#10
Neil Herring, Nidi Tapoulal, Manish Kalla, Xi Ye, Lyudmyla Borysova, Regent Lee, Erica Dall'Armellina, Christopher Stanley, Raimondo Ascione, Chieh-Ju Lu, Adrian P Banning, Robin P Choudhury, Stefan Neubauer, Kim Dora, Rajesh K Kharbanda, Keith M Channon
AIMS: The co-transmitter neuropeptide-Y (NPY) is released during high sympathetic drive, including ST-elevation myocardial infarction (STEMI), and can be a potent vasoconstrictor. We hypothesized that myocardial NPY levels correlate with reperfusion and subsequent recovery following primary percutaneous coronary intervention (PPCI), and sought to determine if and how NPY constricts the coronary microvasculature. METHODS AND RESULTS: Peripheral venous NPY levels were significantly higher in patients with STEMI (n = 45) compared to acute coronary syndromes/stable angina ( n = 48) or with normal coronary arteries (NC, n = 16)...
March 11, 2019: European Heart Journal
https://read.qxmd.com/read/30859227/surgical-resection-of-restrictive-left-ventricular-endomyocardial-fibrosis
#11
Devdas Thomas Inderbitzin, Christoph Krapf, Marc Buser, Carlos A Mestres
No abstract text is available yet for this article.
March 11, 2019: European Heart Journal
https://read.qxmd.com/read/30859220/cardiac-resynchronization-therapy-non-responder-to-responder-conversion-rate-in-the-more-response-to-cardiac-resynchronization-therapy-with-multipoint-pacing-more-crt-mpp-study-results-from-phase-i
#12
Christophe Leclercq, Haran Burri, Antonio Curnis, Peter Paul Delnoy, Christopher A Rinaldi, Johannes Sperzel, Kwangdeok Lee, Leonardo Calò, Alfredo Vicentini, Joaquin Fernandez Concha, Bernard Thibault
AIMS: To assess the impact of MultiPoint™ Pacing (MPP)-programmed according to the physician's discretion-in non-responders to standard biventricular pacing after 6 months. METHODS AND RESULTS: The study enrolled 1921 patients receiving a quadripolar cardiac resynchronization therapy (CRT) system capable of MPP™ therapy. A core laboratory assessed echocardiography at baseline and 6 months and defined volumetric non-response to biventricular pacing as <15% reduction in left ventricular end-systolic volume (LVESV)...
March 11, 2019: European Heart Journal
https://read.qxmd.com/read/30859216/combining-dapt-with-a-ppi-faces-the-acid-test-of-real-world-use
#13
William A E Parker, Robert F Storey
No abstract text is available yet for this article.
March 11, 2019: European Heart Journal
https://read.qxmd.com/read/30859208/how-should-treated-hypertensive-patients-with-systolic-blood-pressure-below-120-mmhg-be-managed
#14
Audes D M Feitosa, Marco A Mota-Gomes, Wilson Nadruz
No abstract text is available yet for this article.
March 11, 2019: European Heart Journal
https://read.qxmd.com/read/30859207/temporal-variations-in-the-triggering-of-myocardial-infarction-by-air-temperature-in-augsburg-germany-1987-2014
#15
Kai Chen, Susanne Breitner, Kathrin Wolf, Regina Hampel, Christa Meisinger, Margit Heier, Wolfgang von Scheidt, Bernhard Kuch, Annette Peters, Alexandra Schneider
AIMS: The association between air temperature and mortality has been shown to vary over time, but evidence of temporal changes in the risk of myocardial infarction (MI) is lacking. We aimed to estimate the temporal variations in the association between short-term exposures to air temperature and MI in the area of Augsburg, Germany. METHODS AND RESULTS: Over a 28-years period from 1987 to 2014, a total of 27 310 cases of MI and coronary deaths were recorded. Daily meteorological parameters were measured in the study area...
March 11, 2019: European Heart Journal
https://read.qxmd.com/read/30859195/widespread-pain-is-a-risk-factor-for-cardiovascular-mortality-results-from-the-framingham-heart-study
#16
Jonas Tesarz, Wolfgang Eich, David Baumeister, Thomas Kohlmann, Ralph D'Agostino, Alexander K Schuster
AIMS: With the introduction of widespread pain (WSP) as a separate diagnostic code in the ICD-11, WSP has now become an own clinical diagnosis independent of the underlying pathophysiology. Research has reported aetiological associations of WSP and cardiovascular diseases. However, studies on mortality risk in individuals with WSP have reported inconsistent results. This study investigates whether there is increased mortality in WSP individuals and establish potential determinants of mortality risk...
March 11, 2019: European Heart Journal
https://read.qxmd.com/read/30859192/incidentally-discovered-left-ventricular-pseudoaneurysm-after-silent-myocardial-infarction-occurred-in-a-young-woman-with-peritoneal-dialysis
#17
Ruka Yoshida, Kensuke Takagi, Yasuhiro Morita, Itsuro Morishima
No abstract text is available yet for this article.
March 11, 2019: European Heart Journal
https://read.qxmd.com/read/30854560/associations-between-vascular-risk-factors-and-brain-mri-indices-in-uk-biobank
#18
Simon R Cox, Donald M Lyall, Stuart J Ritchie, Mark E Bastin, Mathew A Harris, Colin R Buchanan, Chloe Fawns-Ritchie, Miruna C Barbu, Laura de Nooij, Lianne M Reus, Clara Alloza, Xueyi Shen, Emma Neilson, Helen L Alderson, Stuart Hunter, David C Liewald, Heather C Whalley, Andrew M McIntosh, Stephen J Lawrie, Jill P Pell, Elliot M Tucker-Drob, Joanna M Wardlaw, Catharine R Gale, Ian J Deary
AIMS: Several factors are known to increase risk for cerebrovascular disease and dementia, but there is limited evidence on associations between multiple vascular risk factors (VRFs) and detailed aspects of brain macrostructure and microstructure in large community-dwelling populations across middle and older age. METHODS AND RESULTS: Associations between VRFs (smoking, hypertension, pulse pressure, diabetes, hypercholesterolaemia, body mass index, and waist-hip ratio) and brain structural and diffusion MRI markers were examined in UK Biobank (N = 9722, age range 44-79 years)...
March 11, 2019: European Heart Journal
https://read.qxmd.com/read/30851044/pre-treatment-with-a-p2y12-antagonist-before-pci-in-stemi-why-should-we-wait
#19
Jeremie Abtan, P Gabriel Steg
No abstract text is available yet for this article.
March 9, 2019: European Heart Journal
https://read.qxmd.com/read/30851041/reduced-risk-of-gastrointestinal-bleeding-associated-with-proton-pump-inhibitor-therapy-in-patients-treated-with-dual-antiplatelet-therapy-after-myocardial-infarction
#20
Thomas S G Sehested, Nicholas Carlson, Peter W Hansen, Thomas A Gerds, Mette G Charlot, Christian Torp-Pedersen, Lars Køber, Gunnar H Gislason, Mark A Hlatky, Emil L Fosbøl
AIMS: Guidelines differ in their recommendations on therapy to prevent gastrointestinal bleeding for patients treated with dual antiplatelet treatment (DAPT). We sought to investigate the effectiveness of proton pump inhibitors (PPIs) to prevent upper gastrointestinal (UGI) bleeding in patients using DAPT following myocardial infarction (MI) in relation to current European Society of Cardiology guidelines recommendations. METHODS AND RESULTS: We linked Danish nationwide registries to identify patients taking DAPT 7 days following hospital discharge for an acute MI, and excluded individuals on anticoagulation therapy...
March 9, 2019: European Heart Journal
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