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Imipenem/Cilistatin and Fosfomycin for Refractory Methicillin-Resistant Staphylococcus aureus Infection: a Novel Combination Therapy.
Antimicrobial Agents and Chemotherapy 2020 October 6
Given that it unlikely that randomized clinical trials will yield the answers in treating the most challenging bacteremic infections caused by methicillin-resistant Staphylococcus aureus , clinicians, microbiologists, and pharmacists will have to cooperate to discover novel ways in selecting successful individualized antimicrobial therapy for these patients. An example of such a strategy was demonstrated in the identification and utilization of imipenem/cilistatin plus fosfomycin to treat a particularly recalcitrant MRSA bacteremia and spinal abscess.
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