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Journal Article
Research Support, U.S. Gov't, P.H.S.
Successful treatment of radiation nephropathy with angiotensin II blockade.
PURPOSE: The aim of this report is to document the successful treatment of radiation nephropathy.
METHODS: Clinical case report with statistical analysis of evolution of kidney function.
RESULTS: A case of radiation nephropathy was found in a kidney transplant recipient whose kidney transplant had been irradiated with 750 cGy 23 years previously. Use of the angiotensin II blocker, losartan, was associated with significant stabilization of the kidney function.
CONCLUSION: Radiation nephropathy can be successfully treated. Other normal-tissue radiation injuries may also be treatable.
METHODS: Clinical case report with statistical analysis of evolution of kidney function.
RESULTS: A case of radiation nephropathy was found in a kidney transplant recipient whose kidney transplant had been irradiated with 750 cGy 23 years previously. Use of the angiotensin II blocker, losartan, was associated with significant stabilization of the kidney function.
CONCLUSION: Radiation nephropathy can be successfully treated. Other normal-tissue radiation injuries may also be treatable.
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