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Effect of romosozumab in premenopausal women with severe osteoporosis and anorexia nervosa.
Osteoporosis and Sarcopenia 2023 December
OBJECTIVES: This study aims to investigate the effects of romosozumab on bone mineral density (BMD) and bone metabolism.
METHODS: In this retrospective case series, romosozumab was administered to 5 premenopausal female patients with osteoporosis and anorexia nervosa with fragility fractures. BMD and bone turnover marker changes were investigated at 6 months and 1 year after administering romosozumab.
RESULTS: BMD increased and high-turnover bone metabolism decreased 6 months and 1 year after administering romosozumab.
CONCLUSIONS: Romosozumab is useful for treating osteoporosis in patients with anorexia nervosa.
METHODS: In this retrospective case series, romosozumab was administered to 5 premenopausal female patients with osteoporosis and anorexia nervosa with fragility fractures. BMD and bone turnover marker changes were investigated at 6 months and 1 year after administering romosozumab.
RESULTS: BMD increased and high-turnover bone metabolism decreased 6 months and 1 year after administering romosozumab.
CONCLUSIONS: Romosozumab is useful for treating osteoporosis in patients with anorexia nervosa.
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