Xiang Wu, Li Xie, Jin Lei, Jiemin Yao, Jiarong Li, Lixin Ruan, Jun Hong, Guodong Zheng, Yangyu Cheng, Liansheng Long, Jiancun Wang, Chuanping Huang, Qiuyou Xie, Xuelei Zhang, Jianghong He, Xuebin Yu, Shouhua Lv, Zhaosheng Sun, Dai Liu, Xin Li, Jianxin Zhu, Xiaoliang Yang, Dongdong Wang, Yijun Bao, Andrew I R Maas, David Menon, Yajun Xue, Jiyao Jiang, Junfeng Feng, Guoyi Gao
PURPOSE: Severe traumatic brain injury (TBI) leads to acute coma and may result in prolonged disorder of consciousness (pDOC). We aimed to determine whether right median nerve electrical stimulation is a safe and effective treatment for accelerating emergence from coma after TBI. METHODS: This randomised controlled trial was performed in 22 centres in China. Participants with acute coma at 7-14 days after TBI were randomly assigned (1:1) to either routine therapy and right median nerve electrical stimulation (RMNS group) or routine treatment (control group)...
May 13, 2023: Intensive Care Medicine