Mpox whitlow: a novel presentation.

BACKGROUND: Mpox is a rare zoonotic disease with a progressive increase in cases among men who have sex with men (MSM) worldwide in the last months. New complications of this infection have been described.

OBJECTIVES AND METHODS: To describe this new pattern of presentation of Mpox at the level of the finger.

RESULTS: We present 3 cases of Mpox whitlow, a new clinical presentation of Mpox. The patients were 3 MSM with ages ranging from 32 to 49 years. All three had involvement of the third finger of the dominant hand as well as skin lesions at other sites. Two of the three patients had severe inflammation in the digit and proximal arm and were treated with systemic corticosteroids with significant improvement. In 2 of the 3 cases we observed onychodystrophy as a complication. All patients reported sexual intercourse with previous digital anal penetration with the affected finger, which may be the mode of transmission.

CONCLUSIONS: We describe three cases of this Mpox clinical presentation with some distinguishing features that need to be considered.