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British Journal of Anaesthesia

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https://read.qxmd.com/read/31493848/systematic-review-and-consensus-definitions-for-the-standardised-endpoints-in-perioperative-medicine-initiative-patient-centred-outcomes
#1
S R Moonesinghe, A I R Jackson, O Boney, N Stevenson, M T V Chan, T M Cook, M Lane-Fall, C Kalkman, M D Neuman, U Nilsson, M Shulman, P S Myles
BACKGROUND: Patient-centred outcomes are increasingly used in perioperative clinical trials. The Standardised Endpoints in Perioperative Medicine (StEP) initiative aims to define which measures should be used in future research to facilitate comparison between studies and to enable robust evidence synthesis. METHODS: A systematic review was conducted to create a longlist of patient satisfaction, health-related quality of life, functional status, patient well-being, and life-impact measures for consideration...
September 4, 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/31492528/nutritional-neurobiology-and-central-nervous-system-sensitisation-missing-link-in-a-comprehensive-treatment-for-chronic-pain
#2
EDITORIAL
Jo Nijs, Ömer Elma, Sevilay T Yilmaz, Patrick Mullie, Luc Vanderweeën, Peter Clarys, Tom Deliens, Iris Coppieters, Nathalie Weltens, Lukas Van Oudenhove, Anneleen Malfliet
No abstract text is available yet for this article.
September 3, 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/31492527/acquired-loss-of-cardiac-vagal-activity-is-associated-with-myocardial-injury-in-patients-undergoing-noncardiac-surgery-prospective-observational-mechanistic-cohort-study
#3
Shaun M May, Anna Reyes, Gladys Martir, Joseph Reynolds, Laura Gallego Paredes, Shamir Karmali, Robert C M Stephens, David Brealey, Gareth L Ackland
BACKGROUND: Myocardial injury is more frequent after noncardiac surgery in patients with preoperative cardiac vagal dysfunction, as quantified by delayed heart rate (HR) recovery after cessation of cardiopulmonary exercise testing. We hypothesised that serial and dynamic measures of cardiac vagal activity are also associated with myocardial injury after noncardiac surgery. METHODS: Serial autonomic measurements were made before and after surgery in patients undergoing elective noncardiac surgery...
September 3, 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/31492526/electroencephalographic-slow-wave-dynamics-and-loss-of-behavioural-responsiveness-induced-by-ketamine-in-human-volunteers
#4
Jamie Sleigh, Rebecca M Pullon, Phillip E Vlisides, Catherine E Warnaby
BACKGROUND: Previous work on the electroencephalographic (EEG) effects of anaesthetic doses of ketamine has identified a characteristic signature of increased high frequency (beta-gamma) and theta waves alternating with episodic slow waves. It is unclear which EEG parameter is optimal for pharmacokinetic-pharmacodynamic modelling of the hypnotic actions of ketamine, or which EEG parameter is most closely linked to loss of behavioural responsiveness. METHODS: We re-analysed previously published 128-channel scalp EEG data from 15 subjects who had received a 1...
September 3, 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/31474351/a-pilot-study-of-neural-correlates-of-perioperative-executive-function-associated-with-noncardiac-surgery-in-the-elderly
#5
LETTER
Rosaleena Mohanty, Heidi Lindroth, Sara Twadell, Veena A Nair, Vivek Prabhakaran, Robert D Sanders
No abstract text is available yet for this article.
August 29, 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/31474350/days-alive-and-out-of-hospital-after-fast-track-total-hip-and-knee-arthroplasty-an-observational-cohort-study-in-16-137-patients
#6
Christoffer C Jørgensen, Pelle B Petersen, Henrik Kehlet
BACKGROUND: Days alive and out of hospital (DAH) has been proposed as a pragmatic outcome measure of surgical quality. However, there is a lack of procedure specific data or data within an optimised fast-track protocol. Furthermore, information about influence of follow-up duration and types of complications on DAH is limited. METHODS: Observational multicentre cohort study of patients undergoing fast-track total hip (THA) and knee arthroplasty (TKA). Prospective information on comorbidity and complete 90 days follow-up was undertaken through the Danish National Patient Register and chart review...
August 29, 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/31474349/predictors-of-post-anaesthesiology-residency-research-productivity-preliminary-report
#7
LETTER
Elena S Haight, Frances Chen, Pedro Tanaka, John G Brock-Utne, Alex Macario, Eric C Sun, Vivianne L Tawfik
No abstract text is available yet for this article.
August 29, 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/31472923/what-s-in-a-name-on-the-nuance-of-language-in-patient-safety
#8
EDITORIAL
Guttorm Brattebø, Johan Bergström, Christopher Neuhaus
No abstract text is available yet for this article.
August 28, 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/31470983/noble-gas-neuroprotection-xenon-and-argon-protect-against-hypoxic-ischaemic-injury-in-rat-hippocampus-in-vitro-via-distinct-mechanisms
#9
Mariia Koziakova, Katie Harris, Christopher J Edge, Nicholas P Franks, Ian L White, Robert Dickinson
BACKGROUND: Noble gases may provide novel treatments for neurological injuries such as ischaemic and traumatic brain injury. Few studies have evaluated the complete series of noble gases under identical conditions in the same model. METHODS: We used an in vitro model of hypoxia-ischaemia to evaluate the neuroprotective properties of the series of noble gases, helium, neon, argon, krypton, and xenon. Organotypic hippocampal brain slices from mice were subjected to oxygen-glucose deprivation, and injury was quantified using propidium iodide fluorescence...
August 27, 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/31470982/response-to-learning-from-death-br-j-anaesth-2019-123-12-14
#10
LETTER
Anne Meaklim
No abstract text is available yet for this article.
August 27, 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/31451192/slow-magnetic-resonance-oscillations-diagnose-chronic-low-back-pain
#11
EDITORIAL
Jiro Kurata
No abstract text is available yet for this article.
August 23, 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/31451191/the-anaesthetists-role-in-perioperative-infection-control-what-is-the-action-plan
#12
EDITORIAL
Randy W Loftus, Javier H Campos
No abstract text is available yet for this article.
August 23, 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/31451190/performance-of-urgent-surgical-front-of-neck-airway-access-by-head-and-neck-surgeons-general-surgeons-or-anaesthetists-an-in-situ-simulation-study
#13
Peter Groom, Louise Schofield, Natasha Hettiarachchi, Samuel Pickard, Jeremy Brown, John Sandars, Ben Morton
BACKGROUND: The 'cannot intubate cannot oxygenate' (CICO) emergency requires urgent front of neck airway (FONA) access to prevent death. In cases reported to the 4th National Audit Project, the most successful FONA was a surgical technique, almost all of which were performed by surgeons. Subsequently, UK guidelines adopted surgical cricothyroidotomy as the preferred emergency surgical FONA technique. Despite regular skills-based training, anaesthetists may still be unwilling to perform an emergency surgical FONA...
August 23, 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/31443917/peripartum-cardiomyopathy-a-single-institution-5-yr-experience
#14
LETTER
Shahenaz Elsamragy, Rovnat Babazade, Michelle Simon, Mohamed Ibrahim, Rakesh B Vadhera
No abstract text is available yet for this article.
August 20, 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/31443916/machine-learning-in-anaesthesia-reactive-proactive%C3%A2-predictive
#15
EDITORIAL
Pedro L Gambus, Sebastian Jaramillo
No abstract text is available yet for this article.
August 20, 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/31439308/state-of-the-clinical-science-of-perioperative-brain-health-report-from-the-american-society-of-anesthesiologists-brain-health-initiative-summit-2018
#16
Elizabeth Mahanna-Gabrielli, Katie J Schenning, Lars I Eriksson, Jeffrey N Browndyke, Clinton B Wright, Lis Evered, David A Scott, Nae Yah Wang, Charles H Brown, Esther Oh, Patrick Purdon, Sharon Inouye, Miles Berger, Robert A Whittington, Stacie Deiner
Cognitive recovery after anaesthesia and surgery is a concern for older adults, their families, and caregivers. Reports of patients who were 'never the same' prompted a scientific inquiry into the nature of what patients have experienced. In June 2018, the ASA Brain Health Initiative held a summit to discuss the state of the science on perioperative cognition, and to create an implementation plan for patients and providers leveraging the current evidence. This group included representatives from the AARP (formerly the American Association of Retired Persons), American College of Surgeons, American Heart Association, and Alzheimer's Association Perioperative Cognition and Delirium Professional Interest Area...
August 19, 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/31420087/making-pharmacokinetics-useful
#17
EDITORIAL
S L Shafer
No abstract text is available yet for this article.
August 13, 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/31402044/towards-a-coordinated-national-strategy-to-improve-survival-after-emergency-laparotomy
#18
EDITORIAL
Dave Murray, Rupert M Pearse, Nial Quiney
No abstract text is available yet for this article.
August 8, 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/31399212/orexin-activated-emergence-from-isoflurane-anaesthesia-involves-excitation-of-ventral-tegmental-area-dopaminergic-neurones-in-rats
#19
J Li, H Li, D Wang, Y Guo, X Zhang, M Ran, C Yang, Q Yang, H Dong
BACKGROUND: Orexin can facilitate emergence after general anaesthesia via multiple neural pathways. Dopaminergic neurones in the ventral tegmental area (VTA) participate in behavioural arousal from anaesthesia. We investigated the regulation of dopaminergic VTA neurones by orexinergic neurones during emergence from general anaesthesia. METHODS: Orexins were microinjected into the VTA to determine the effects on isoflurane anaesthesia induction, emergence, and maintenance...
August 6, 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/31395306/modulatory-effects-of-different-exercise-modalities-on-the-functional-connectivity-of-the-periaqueductal-grey-and-ventral-tegmental-area-in-patients-with-knee-osteoarthritis-a-randomised-multimodal-magnetic-resonance-imaging-study
#20
Jiao Liu, Lidian Chen, Xiangli Chen, Kun Hu, Youxue Tu, Meiqin Lin, Jia Huang, Weilin Liu, Jinsong Wu, Zhijie Qiu, Jingfang Zhu, Ming Li, Joel Park, Georgia Wilson, Courtney Lang, Guanli Xie, Jing Tao, Jian Kong
BACKGROUND: Knee osteoarthritis is a prevalent disorder with unsatisfactory treatment options. Both physical and mindful exercises may be able to relieve its pain symptoms. We compared the modulatory effects of different exercise modalities on the periaqueductal grey (PAG) and ventral tegmental area (VTA), which play important roles in descending opioidergic pathways and reward/motivation systems in patients with knee osteoarthritis. METHODS: We recruited and randomised 140 patients into Tai Chi, Baduanjin, stationary cycling, and health education control groups for 12 weeks...
August 5, 2019: British Journal of Anaesthesia
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