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British Journal of Anaesthesia

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https://read.qxmd.com/read/30770064/comment-on-problems-with-colour-interpretation-of-syringe-labels-not-just-colour-deficient-clinicians-br-j-anaesth-2018-121-1370-3
#1
LETTER
Patrick Tapley, Rhys Lewis
No abstract text is available yet for this article.
March 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30770063/universal-videolaryngoscopy-the-importance-of-choosing-the-right-device-reply-to-cognitive-re-engineering-after-a-15-year-experience-with-routine-videolaryngoscopy-br-j-anaesth-2019-122-e57-8
#2
LETTER
Tim M Cook, Fiona E Kelly, Nancy Boniface, Chris Seller
No abstract text is available yet for this article.
March 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30770062/response-to-evaluation-of-the-analgesia-nociception-index-for-monitoring-intraoperative-analgesia-in-children-br-j-anaesth-2018-121-462-8
#3
LETTER
Eftychia Sousi, Dominic Peter Douglas Nielsen, Anil Rustamali Visram
No abstract text is available yet for this article.
March 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30770061/cognitive-re-engineering-after-a-15-year-experience-with-routine-videolaryngoscopy
#4
LETTER
Dario Caldiroli, Aidan J Byrne
No abstract text is available yet for this article.
March 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30770060/response-to-comment-on-fascial-layers-influence-the-spread-of-injectate-during-ultrasound-guided-infraclavicular-brachial-plexus-block-a-cadaver-study-br-j-anaesth-2019-122-e54-5
#5
LETTER
David Brenner, Padraig Mahon, Gabriella Iohom, Michael Cronin, Carrie O'Flynn, George Shorten
No abstract text is available yet for this article.
March 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30770059/comment-on-fascial-layers-influence-the-spread-of-injectate-during-ultrasound-guided-infraclavicular-brachial-plexus-block-a-cadaver-study-br-j-anaesth-2018-121-876-82
#6
LETTER
Georg Feigl, Peter Marhofer
No abstract text is available yet for this article.
March 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30770058/computer-simulation-clarifies-mechanisms-of-carbon-dioxide-clearance-during-apnoea
#7
M Laviola, A Das, M Chikhani, D G Bates, J G Hardman
BACKGROUND: Apnoeic oxygenation can come close to matching the oxygen demands of the apnoeic patient but does not facilitate carbon dioxide (CO2 ) elimination, potentially resulting in dangerous hypercapnia. Numerous studies have shown that high-flow nasal oxygen administration prevents hypoxaemia, and appears to reduce the rate of increase of arterial CO2 partial pressure (PaCO2 ), but evidence is lacking to explain these effects. METHODS: We extended a high-fidelity computational simulation of cardiopulmonary physiology to include modules allowing variable effects of: (a) cardiogenic oscillations affecting intrathoracic gas spaces, (b) gas mixing within the anatomical dead space, (c) insufflation into the trachea or above the glottis, and (d) pharyngeal pressure oscillation...
March 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30770057/incidence-and-risk-factors-of-hypoxaemia-after-preoxygenation-at-induction-of-anaesthesia
#8
C Baillard, M Boubaya, E Statescu, M Collet, A Solis, J Guezennec, V Levy, O Langeron
BACKGROUND: The incidence of hypoxaemia related to airway management is still a matter of concern. Our aim was to determine the factors that contribute to hypoxaemia during induction of anaesthesia after a standardised preoxygenation procedure. METHODS: The study was a multicentre and prospective observational trial. It evaluated the incidence of hypoxaemia at induction of anaesthesia in adult patients. The primary endpoint was the incidence of hypoxaemia defined as pulse oximetry of arterial oxyhaemoglobin saturation (SpO2 ) <95%...
March 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30770056/neurological-and-histological-outcomes-after-subarachnoid-injection-of-a-liposomal-bupivacaine-suspension-in-pigs-a-pilot-study
#9
J Zel, A Hadzic, E Cvetko, A Seliskar, M Damjanovska, M M Kuroda, S Sega Jazbec, T Stopar Pintaric
BACKGROUND: An injectable liposomal bupivacaine suspension (EXPAREL™) is approved by the US Food and Drug Administration for analgesia by tissue infiltration and interscalene brachial plexus, but not for use in the neuraxial space. This pilot study describes neurological and histological outcomes of escalating doses of this extended-release formulation of bupivacaine after subarachnoid administration. METHODS: Twenty-five pigs (Sus scrofa domesticus) weighing 36...
March 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30770055/retrospective-analysis-of-30-day-unplanned-readmission-after-major-abdominal-surgery-with-reversal-by-sugammadex-or-neostigmine
#10
Tak Kyu Oh, Ah-Young Oh, Jung-Hee Ryu, Bon-Wook Koo, In-Ae Song, Sun Woo Nam, Hee-Jung Jee
BACKGROUND: Sugammadex is associated with fewer postoperative complications, but its impact on 30-day unplanned readmission is unclear. METHODS: This was a single-centre retrospective observational study of patients after major abdominal surgery between 2010 and 2017, where rocuronium was the only neuromuscular blocker used. The primary endpoint was the difference in incidence of 30-day unplanned readmission between reversal with sugammadex or neostigmine. The secondary endpoints were the length of hospital stay after surgery and related hospital charges (total charges excluding those related to surgery and anaesthesia)...
March 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30770054/association-between-night-time-surgery-and-occurrence-of-intraoperative-adverse-events-and-postoperative-pulmonary-complications
#11
A Cortegiani, C Gregoretti, A S Neto, S N T Hemmes, L Ball, J Canet, M Hiesmayr, M W Hollmann, G H Mills, M F V Melo, C Putensen, W Schmid, P Severgnini, H Wrigge, M Gama de Abreu, M J Schultz, P Pelosi
BACKGROUND: The aim of this post hoc analysis of a large cohort study was to evaluate the association between night-time surgery and the occurrence of intraoperative adverse events (AEs) and postoperative pulmonary complications (PPCs). METHODS: LAS VEGAS (Local Assessment of Ventilatory Management During General Anesthesia for Surgery) was a prospective international 1-week study that enrolled adult patients undergoing surgical procedures with general anaesthesia and mechanical ventilation in 146 hospitals across 29 countries...
March 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30770053/maresin-1-attenuates-neuroinflammation-in-a-mouse-model-of-perioperative-neurocognitive-disorders
#12
T Yang, G Xu, P T Newton, A S Chagin, S Mkrtchian, M Carlström, X-M Zhang, R A Harris, M Cooter, M Berger, K R Maddipati, K Akassoglou, N Terrando
BACKGROUND: Resolution of inflammation is an active and dynamic process after surgery. Maresin 1 (MaR1) is one of a growing number of specialised pro-resolving lipids biosynthesised by macrophages that regulates acute inflammation. We investigated the effects of MaR1 on postoperative neuroinflammation, macrophage activity, and cognitive function in mice. METHODS: Adult male C57BL/6 (n=111) and Ccr2RFP/+ Cx3cr1GFP/+ (n=54) mice were treated with MaR1 before undergoing anaesthesia and orthopaedic surgery...
March 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30770052/renal-perfusion-oxygenation-and-sympathetic-nerve-activity-during-volatile-or-intravenous-general-anaesthesia-in-sheep
#13
Naoya Iguchi, Junko Kosaka, Lindsea C Booth, Yoko Iguchi, Roger G Evans, Rinaldo Bellomo, Clive N May, Yugeesh R Lankadeva
BACKGROUND: Global and intra-renal perfusion and oxygenation may be affected by the choice of anaesthetic. We compared the effects of isoflurane with those of propofol and fentanyl on renal blood flow (RBF) and intra-renal perfusion and oxygenation, and assessed how these were associated with renal sympathetic nerve activity (RSNA). METHODS: A renal artery flow probe and laser Doppler and oxygen-sensing probes were surgically implanted in the renal medulla and cortex in 20 Merino ewes...
March 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30770051/capnodynamic-determination-of-cardiac-output-in-hypoxia-induced-pulmonary-hypertension-in-pigs
#14
J Karlsson, M Wallin, M Hallbäck, P A Lönnqvist
BACKGROUND: Effective pulmonary blood flow (COEPBF ) has recently been validated for its ability to measure cardiac output (CO) in children and animals. This study compared COEPBF with the Fick method (COFick ) and CO measurements using an invasive pulmonary artery flow probe (COTS ). The aim of the study was to validate COEPBF against these reference methods in a porcine model of hypoxia-induced selective pulmonary hypertension. METHODS: Ten anaesthetised mechanically ventilated piglets (median weight 23...
March 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30770050/effectiveness-of-80-vs-30-35-fraction-of-inspired-oxygen-in-patients-undergoing-surgery-an-updated-systematic-review-and-meta-analysis
#15
REVIEW
Stijn de Jonge, Matthias Egger, Asad Latif, Yoon Kong Loke, Sean Berenholtz, Marja Boermeester, Benedetta Allegranzi, Joseph Solomkin
BACKGROUND: In 2016, the World Health Organization (WHO) strongly recommended the use of a high fraction of inspired oxygen (FiO2 ) in adult patients undergoing general anaesthesia to reduce the risk of surgical site infection (SSI). Since then, further trials have been published, trials included previously have come under scrutiny, and one article was retracted. We updated the systematic review on which the recommendation was based. METHODS: We performed a systematic literature search from January 1990 to April 2018 for RCTs comparing the effect of high (80%) vs standard (30-35%) FiO2 on the incidence of SSI...
March 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30770049/safety-of-80-vs-30-35-fraction-of-inspired-oxygen-in-patients-undergoing-surgery-a-systematic-review-and-meta-analysis
#16
REVIEW
Katharina Mattishent, Menaka Thavarajah, Ashnish Sinha, Adam Peel, Matthias Egger, Joseph Solomkin, Stijn de Jonge, Asad Latif, Sean Berenholtz, Benedetta Allegranzi, Yoon Kong Loke
BACKGROUND: Evidence-based guidelines from the World Health Organization (WHO) have recommended a high (80%) fraction of inspired oxygen (FiO2 ) to reduce surgical site infection in adult surgical patients undergoing general anaesthesia with tracheal intubation. However, there is ongoing debate over the safety of high FiO2 . We performed a systematic review to define the relative risk of clinically relevant adverse events (AE) associated with high FiO2 . METHODS: We reviewed potentially relevant articles from the WHO review supporting the recommendation, including an updated (July 2018) search of EMBASE and PubMed for randomised and non-randomised controlled studies reporting AE in surgical patients receiving 80% FiO2 compared with 30-35% FiO2 ...
March 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30770048/choosing-wisely-just-because-we-can-does-it-mean-we-should
#17
EDITORIAL
Ramai Santhirapala, Lee A Fleisher, Michael P W Grocott
No abstract text is available yet for this article.
March 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30770047/beyond-failure-to-rescue-the-time-has-come-for-continuous-ward-monitoring
#18
EDITORIAL
Daniel I Sessler, Bernd Saugel
No abstract text is available yet for this article.
March 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30770046/land-of-confusion-anaesthetic-management-during-thrombectomy-for-acute-ischaemic-stroke
#19
EDITORIAL
Allart M Venema, Maarten Uyttenboogaart, Anthony R Absalom
No abstract text is available yet for this article.
March 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30770045/spinal-exparel%C3%A2-an-extended-duration-of-preclinical-study-needed
#20
EDITORIAL
James C Eisenach, Tony L Yaksh
No abstract text is available yet for this article.
March 2019: British Journal of Anaesthesia
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