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British Journal of Anaesthesia

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https://read.qxmd.com/read/30857614/diagnosis-of-inadvertent-oesophageal-intubation-with-h-type-tracheo-oesophageal-fistula
#1
LETTER
Satyajeet Misra, Bikram Kishore Behera, Manoj Kumar Mohanty, Subrat Kumar Sahoo
No abstract text is available yet for this article.
April 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30857613/the-no-trace-wrong-place-campaign
#2
LETTER
Tim M Cook, A William Harrop-Griffiths, David K Whitaker, Alistair F McNarry, Anil Patel, Barry McGuire
No abstract text is available yet for this article.
April 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30857612/reducing-the-risk-of-confirmation-bias-in-unrecognised-oesophageal-intubation
#3
LETTER
Daniel Jafferji, Rachael Morris, Nicholas Levy
No abstract text is available yet for this article.
April 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30857611/nocturnal-desaturation-early-after-delivery-impact-of-delivery-type-and-the-beneficial-effects-of-fowler-s-position
#4
LETTER
Nobuko Fujita, Stephanie D Grabitz, Christina H Shin, Philip E Hess, Noomi Mueller, Brian T Bateman, Jeffrey L Ecker, Osamu Takahashi, Timothy T Houle, Yasuko Nagasaka, Matthias Eikermann
No abstract text is available yet for this article.
April 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30857610/hepatotoxicity-after-sevoflurane-anaesthesia-a-new-twist-to-an-old-story
#5
LETTER
Shobana Rajan, Deepali Garg, Kenneth C Cummings, Ajit A Krishnaney
No abstract text is available yet for this article.
April 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30857609/dexamethasone-as-an-adjuvant-for-peripheral-nerve-blockade-a-randomised-triple-blinded-crossover-study-in-volunteers
#6
Peter Marhofer, Malachy Columb, Phil M Hopkins, Manfred Greher, Daniela Marhofer, Max R Levi Bienzle, Markus Zeitlinger
BACKGROUND: The efficacy of dexamethasone in extending the duration of local anaesthetic block is uncertain. In a randomised controlled triple blind crossover study in volunteers, we tested the hypothesis that neither i.v. nor perineurally administered dexamethasone prolongs the sensory block achieved with ropivacaine. METHODS: Ultrasound-guided ulnar nerve blocks (ropivacaine 0.75% wt/vol, 3 ml, with saline 1 ml with or without dexamethasone 4 mg) were performed on three occasions in 24 male volunteers along with an i...
April 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30857608/retroclavicular-vs-supraclavicular-brachial-plexus-block-for-distal-upper-limb-surgery-a-randomised-controlled-single-blinded-trial
#7
Sina Grape, Amit Pawa, Eric Weber, Eric Albrecht
BACKGROUND: Regional anaesthesia for upper limb surgery is routinely performed with brachial plexus blocks. A retroclavicular brachial plexus block has recently been described, but has not been adequately compared with another approach. This randomised controlled single-blinded trial tested the hypothesis that the retroclavicular approach, when compared with the supraclavicular approach, would increase the success rate. METHODS: One hundred and twenty ASA physical status 1-3 patients undergoing distal upper limb surgery were randomised to receive an ultrasound-guided retroclavicular or supraclavicular brachial plexus block with 30 mL of a 1:1 mixture of mepivacaine 1% and ropivacaine 0...
April 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30857607/caudal-epidural-blocks-in-paediatric-patients-a-review-and-practical-considerations
#8
REVIEW
Marion Wiegele, Peter Marhofer, Per-Arne Lönnqvist
Caudal epidural blockade in children is one of the most widely administered techniques of regional anaesthesia. Recent clinical studies have answered major pharmacodynamic and pharmacokinetic questions, thus providing the scientific background for safe and effective blocks in daily clinical practice and demonstrating that patient selection can be expanded to range from extreme preterm births up to 50 kg of body weight. This narrative review discusses the main findings in the current literature with regard to patient selection (sub-umbilical vs mid-abdominal indications, contraindications, low-risk patients with spinal anomalies); anatomical considerations (access problems, age and body positioning, palpation for needle insertion); technical considerations (verification of needle position by ultrasound vs landmarks vs 'whoosh' or 'swoosh' testing); training and equipment requirements (learning curve, needle types, risk of tissue spreading); complications and safety (paediatric regional anaesthesia, caudal blocks); local anaesthetics (bupivacaine vs ropivacaine, risk of toxicity in children, management of toxic events); adjuvant drugs (clonidine, dexmedetomidine, opioids, ketamine); volume dosing (dermatomal reach, cranial rebound); caudally accessed lumbar or thoracic anaesthesia (contamination risk, verifying catheter placement); and postoperative pain...
April 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30857606/systematic-review-and-consensus-definitions-for-the-standardised-endpoints-in-perioperative-medicine-step-initiative-infection-and-sepsis
#9
REVIEW
Jonathan Barnes, Jennifer Hunter, Steve Harris, Manu Shankar-Hari, Elisabeth Diouf, Ib Jammer, Cor Kalkman, Andrew A Klein, Tomas Corcoran, Stefan Dieleman, Michael P W Grocott, Michael G Mythen
BACKGROUND: Perioperative infection and sepsis are of fundamental concern to perioperative clinicians. However, standardised endpoints are either poorly defined or not routinely implemented. The Standardised Endpoints in Perioperative Medicine (StEP) initiative was established to derive a set of standardised endpoints for use in perioperative clinical trials. METHODS: We undertook a systematic review to identify measures of infection and sepsis used in the perioperative literature...
April 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30857605/female-rats-are-more-vulnerable-to-lasting-cognitive-impairment-after-isoflurane-exposure-on-postnatal-day-4-than-7
#10
Jennifer M Sasaki Russell, Gregory A Chinn, Deenu Maharjan, Yasmine Eichbaum, Jeffrey W Sall
BACKGROUND: The factors determining peak susceptibility of the developing brain to anaesthetics are unclear. It is unknown why postnatal day 7 (P7) male rats are more vulnerable to anaesthesia-induced memory deficits than littermate females. Given the precocious development of certain regions in the female brain during the neonatal critical period, we hypothesised that females are susceptible to anaesthetic brain injury at an earlier time point than previously tested. METHODS: Female rats were exposed to isoflurane (Iso) 1 minimum alveolar concentration or sham anaesthesia at P4 or P7...
April 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30857604/depth-of-sedation-as-an-interventional-target-to-reduce-postoperative-delirium-mortality-and-functional-outcomes-of-the-strategy-to-reduce-the-incidence-of-postoperative-delirium-in-elderly-patients-randomised-clinical-trial
#11
Frederick Sieber, Karin J Neufeld, Allan Gottschalk, George E Bigelow, Esther S Oh, Paul B Rosenberg, Simon C Mears, Kerry J Stewart, Jean-Pierre P Ouanes, Mahmood Jaberi, Erik A Hasenboehler, Nae-Yuh Wang
BACKGROUND: The Strategy to Reduce the Incidence of Postoperative Delirium in the Elderly trial tested the hypothesis that limiting sedation during spinal anaesthesia decreases in-hospital postoperative delirium after hip fracture repair. This manuscript reports the secondary outcomes of this trial, including mortality and function. METHODS: Two hundred patients (≥65 yr) undergoing hip fracture repair with spinal anaesthesia were randomised to heavier [modified Observer's Assessment of Alertness/Sedation score (OAA/S) 0-2] or lighter (OAA/S 3-5) sedation, and were assessed for postoperative delirium...
April 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30857603/performance-on-the-operant-test-battery-in-young-children-exposed-to-procedures-requiring-general-anaesthesia-the-mask-study
#12
David O Warner, John J Chelonis, Merle G Paule, Ryan D Frank, Minji Lee, Michael J Zaccariello, Slavica K Katusic, Darrell R Schroeder, Andrew C Hanson, Phillip J Schulte, Robert T Wilder, Juraj Sprung, Randall P Flick
BACKGROUND: It is not known whether the neurotoxicity produced by anaesthetics administered to young animals can also occur in children. Exposure of infant macaques to ketamine impairs performance in selected domains of the Operant Test Battery (OTB), which can also be administered to children. This study determined whether a similar pattern of results on the OTB is found in children exposed to procedures requiring general anaesthesia before age 3 yr. METHODS: We analysed data from the Mayo Anesthesia Safety in Kids (MASK) study, in which unexposed, singly-exposed, and multiply-exposed children born in Olmsted County, MN, USA, from 1994 to 2007 were sampled using a propensity-guided approach and prospectively underwent OTB testing at ages 8-12 or 15-20 yr, using five tasks that generated 15 OTB test scores...
April 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30857602/postoperative-critical-care-and-high-acuity-care-provision-in-the-united-kingdom-australia-and-new-zealand
#13
Danny Jon Nian Wong, Scott Popham, Andrew Marshall Wilson, Lisa M Barneto, Helen A Lindsay, Laura Farmer, David Saunders, Sophie Wallace, Douglas Campbell, Paul S Myles, Steve Kendrick Harris, Suneetha Ramani Moonesinghe
BACKGROUND: Decisions to admit high-risk postoperative patients to critical care may be affected by resource availability. We aimed to quantify adult ICU/high-dependency unit (ICU/HDU) capacity in hospitals from the UK, Australia, and New Zealand (NZ), and to identify and describe additional 'high-acuity' beds capable of managing high-risk patients outside the ICU/HDU environment. METHODS: We used a modified Delphi consensus method to design a survey that was disseminated via investigator networks in the UK, Australia, and NZ...
April 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30857601/propofol-infusion-syndrome-a-structured-literature-review-and-analysis-of-published-case-reports
#14
REVIEW
Scott Hemphill, Luke McMenamin, Mark C Bellamy, Philip M Hopkins
Propofol infusion syndrome is a rare, potentially fatal condition first described in children in the 1990s and later reported in adults. We provide a narrative review of what is currently known about propofol infusion syndrome, including a structured analysis of all published case reports; child and adult cases were analysed separately as propofol is no longer used for long-term sedation in children. The review contains an update on current knowledge of the pathophysiology of this condition along with recommendations for its diagnosis, prevention, and management...
April 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30857600/effects-of-vasopressin-during-a-pulmonary-hypertensive-crisis-induced-by-acute-hypoxia-in-a-rat-model-of-pulmonary-hypertension
#15
Yoh Sugawara, Yusuke Mizuno, Shinya Oku, Takahisa Goto
BACKGROUND: A pulmonary hypertensive crisis (PHC) can be a life-threatening condition. We established a PHC model by exposing rats with monocrotaline (MCT)-induced pulmonary hypertension to acute hypoxia, and investigated the effects of vasopressin, phenylephrine, and norepinephrine on the PHC. METHODS: Four weeks after MCT 60 mg kg-1 administration i.v., right ventricular systolic pressure (RVSP), systolic BP (SBP), mean BP (MBP), cardiac index (CI), and pulmonary vascular resistance index (PVRI) were measured...
April 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30857599/vasoactive-inotropic-score-and-the-prediction-of-morbidity-and-mortality-after-cardiac-surgery
#16
Timo Koponen, Johanna Karttunen, Tadeusz Musialowicz, Laura Pietiläinen, Ari Uusaro, Pasi Lahtinen
BACKGROUND: The vasoactive-inotropic score (VIS) predicts mortality and morbidity after paediatric cardiac surgery. Here we examined whether VIS also predicted outcome in adults after cardiac surgery, and compared predictive capability between VIS and three widely used scoring systems. METHODS: This single-centre retrospective cohort study included 3213 cardiac surgery patients. Maximal VIS (VISmax ) was calculated using the highest doses of vasoactive and inotropic medications administered during the first 24 h post-surgery...
April 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30857598/hypnotic-depth-and-postoperative-death-a-bayesian-perspective-and-an-independent-discussion-of-a-clinical-trial
#17
Phillip E Vlisides, John P A Ioannidis, Michael S Avidan
No abstract text is available yet for this article.
April 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30857597/independent-discussion-sections-for-improving-inferential-reproducibility-in-published-research
#18
Michael S Avidan, John P A Ioannidis, George A Mashour
There is a reproducibility crisis in science. There are many potential contributors to replication failure in research across the translational continuum. In this perspective piece, we focus on the narrow topic of inferential reproducibility. Although replication of methods and results is necessary to demonstrate reproducibility, it is not sufficient. Also fundamental is consistent interpretation in the Discussion section. Current deficiencies in the Discussion sections of manuscripts might limit the inferential reproducibility of scientific research...
April 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30857596/dexamethasone-and-peripheral-nerve-blocks-back-to-basic-science
#19
EDITORIAL
David Hewson, Nigel Bedforth, Colin McCartney, Jonathan Hardman
No abstract text is available yet for this article.
April 2019: British Journal of Anaesthesia
https://read.qxmd.com/read/30857595/patient-important-outcomes-and-core-outcome-sets-increased-attention-needed
#20
EDITORIAL
Morten H Møller
No abstract text is available yet for this article.
April 2019: British Journal of Anaesthesia
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