Yuki Suigiyama, Tomonori Takazawa, Natsuko Watanabe, Kiyoko Bito, Tetsuhiro Fujiyoshi, Shinsuke Hamaguchi, Takashi Haraguchi, Tatsuo Horiuchi, Yoshinori Kamiya, Noboru Maruyama, Hitoshi Masumo, Harumasa Nakazawa, Kazuhiro Nagumo, Masaki Orihara, Jun Sato, Kenichi Sekimoto, Kenichiro Takahashi, Mutsumi Uchiyama, Kazunobu Takahashi, Masao Yamaguchi, Mikito Kawamata
BACKGROUND: Diagnosis of perioperative anaphylaxis is difficult because of its non-specific and variable signs and symptoms. Therapeutic agents used to treat anaphylaxis and anaesthesiologist responses also vary depending on the case, which might affect outcomes; however, only a few studies have focused on these factors. METHODS: This prospective study of perioperative anaphylaxis, a part of the Japanese Epidemiologic Study for Perioperative Anaphylaxis, investigated the clinical signs, its severity, therapeutic drugs, epinephrine administration, and anaesthesiologist responses in cases of perioperative anaphylaxis to assess trends and variability...
March 24, 2023: British Journal of Anaesthesia