journal
https://read.qxmd.com/read/34281718/association-between-intraoperative-mean-arterial-pressure-and-postoperative-complications-is-independent-of-cardiac-index-in-patients-undergoing-noncardiac-surgery
#1
LETTER
Kamal Maheshwari, Xuan Pu, Eva Rivas, Bernd Saugel, Alparslan Turan, Marc T Schmidt, Kurt Ruetzler, Christian Reiterer, Barbara Kabon, Andrea Kurz, Daniel I Sessler
No abstract text is available yet for this article.
July 16, 2021: British Journal of Anaesthesia
https://read.qxmd.com/read/34275605/comparison-of-fascial-plane-blocks-on-quality-of-recovery-for-minimally-invasive-thoracic-surgery-response-to-br-j-anaesth-2021-127-e14-5
#2
LETTER
Dylan T Finnerty, Donal J Buggy
No abstract text is available yet for this article.
July 16, 2021: British Journal of Anaesthesia
https://read.qxmd.com/read/34275604/comparing-high-flow-nasal-oxygenation-or-standard-oxygenation-for-gastrointestinal-endoscopy-with-sedation-response-to-brj-anaesth-2021
#3
LETTER
Mai-Anh Nay, Thierry Boulain
No abstract text is available yet for this article.
July 15, 2021: British Journal of Anaesthesia
https://read.qxmd.com/read/34275603/a-bayesian-analysis-of-mortality-outcomes-in-multicentre-clinical-trials-in-critical-care
#4
David Sidebotham, Ivor Popovich, Thomas Lumley
BACKGROUND: Multicentre RCTs are widely used by critical care researchers to answer important clinical questions. However, few trials evaluating mortality outcomes report statistically significant results. We hypothesised that the low proportion of trials reporting statistically significant differences for mortality outcomes is plausibly explained by lower-than-expected effect sizes combined with a low proportion of participants who could realistically benefit from studied interventions...
July 15, 2021: British Journal of Anaesthesia
https://read.qxmd.com/read/34275602/environmental-impact-of-medical-oxygen-production-in-australia-comment-on-br-j-anaesth-2020-125-773-8
#5
LETTER
Richard Seglenieks, Scott McAlister, Forbes McGain
No abstract text is available yet for this article.
July 15, 2021: British Journal of Anaesthesia
https://read.qxmd.com/read/34272059/long-term-evidence-of-neonatal-anaesthesia-neurotoxicity-linked-to-behavioural-phenotypes-in-monkeys-where-do-we-go-from-here
#6
EDITORIAL
Jessica Raper, Harold K Simon, Pradip P Kamat
Whether anaesthesia exposure early in life leads to brain damage with long-lasting structural and behavioural consequences in primates has not been conclusively determined. A study in the British Journal of Anaesthesia by Neudecker and colleagues found that 2 yr after early anaesthesia exposure, monkeys exhibited signs of chronic astrogliosis which correlate with behavioural deficits. Given the increasing frequency of exposure to anaesthetics in infancy in humans, clinical trials are greatly needed to understand how sedative/anaesthetic agents may be impacting brain and behaviour development...
July 13, 2021: British Journal of Anaesthesia
https://read.qxmd.com/read/34272058/intraoperative-ketorolac-may-interact-with-patient-specific-tumour-genomics-to-modify-recurrence-risk-in-lung-adenocarcinoma-an-exploratory-analysis
#7
LETTER
James G Connolly, Joseph R Scarpa, Hersh V Gupta, Kay See Tan, Brooke Mastrogiacomo, Joseph Dycoco, Raul Caso, Gregory D Jones, Francisco Sanchez-Vega, Prasad S Adusumilli, Gaetano Rocco, James M Isbell, Matthew J Bott, Takeshi Irie, Patrick J McCormick, Gregory W Fischer, David R Jones, Joshua S Mincer
No abstract text is available yet for this article.
July 13, 2021: British Journal of Anaesthesia
https://read.qxmd.com/read/34266661/astrogliosis-in-juvenile-non-human-primates-2-years-after-infant-anaesthesia-exposure
#8
Viola Neudecker, Jose F Perez-Zoghbi, Lauren D Martin, Gregory A Dissen, Marjorie R Grafe, Ansgar M Brambrink
BACKGROUND: Infant anaesthesia causes acute brain cell apoptosis, and later in life cognitive deficits and behavioural alterations, in non-human primates (NHPs). Various brain injuries and neurodegenerative conditions are characterised by chronic astrocyte activation (astrogliosis). Glial fibrillary acidic protein (GFAP), an astrocyte-specific protein, increases during astrogliosis and remains elevated after an injury. Whether infant anaesthesia is associated with a sustained increase in GFAP is unknown...
July 12, 2021: British Journal of Anaesthesia
https://read.qxmd.com/read/34256925/delaying-initiation-of-diuretics-in-critically-ill-patients-with-recent-vasopressor-use-and-high-positive-fluid-balance
#9
Zachary Shahn, Li-Wei H Lehman, Roger G Mark, Daniel Talmor, Somnath Bose
BACKGROUND: Fluid overload is associated with poor outcomes. Clinicians might be reluctant to initiate diuretic therapy for patients with recent vasopressor use. We estimated the effect on 30-day mortality of withholding or delaying diuretics after vasopressor use in patients with probable fluid overload. METHODS: This was a retrospective cohort study of adults admitted to ICUs of an academic medical centre between 2008 and 2012. Using a database of time-stamped patient records, we followed individuals from the time they first required vasopressor support and had >5 L cumulative positive fluid balance (plus additional inclusion/exclusion criteria)...
July 10, 2021: British Journal of Anaesthesia
https://read.qxmd.com/read/34253321/team-factors-influence-emotions-and-stress-in-a-non-operating-room-anaesthetising-location
#10
LETTER
Hedwig Schroeck, Andreas H Taenzer, Karen E Schifferdecker
No abstract text is available yet for this article.
July 9, 2021: British Journal of Anaesthesia
https://read.qxmd.com/read/34253320/socioeconomic-status-and-perioperative-risk-comment-on-br-j-anaesth-2021-126-642-51
#11
LETTER
Helen Williams, Iain Moppett
No abstract text is available yet for this article.
July 9, 2021: British Journal of Anaesthesia
https://read.qxmd.com/read/34247770/comparing-high-flow-nasal-oxygenation-or-standard-oxygenation-for-gastrointestinal-endoscopy-with-sedation-comment-on-br-j-anaesth-2021-127-133-42
#12
LETTER
Fu S Xue, Liu J Z Shao, Shao H Liu
No abstract text is available yet for this article.
July 8, 2021: British Journal of Anaesthesia
https://read.qxmd.com/read/34246461/pharmacokinetic-properties-of-remimazolam-in-subjects-with-hepatic-or-renal-impairment
#13
Thomas Stöhr, Pieter J Colin, Joachim Ossig, Marija Pesic, Keith Borkett, Peter Winkle, Michel M R F Struys, Frank Schippers
BACKGROUND: Remimazolam is a new benzodiazepine for procedural sedation and general anaesthesia. The aim of this study was to characterise its pharmacokinetic properties and safety in renally and hepatically impaired subjects. METHODS: Two separate trials were conducted in patients with hepatic (n=11) or renal impairment (n=11) compared with matched healthy subjects (n=9 and n=12, respectively). The hepatic impairment trial was an open-label adaptive 'Reduced Design' trial, using a single bolus of remimazolam 0...
July 8, 2021: British Journal of Anaesthesia
https://read.qxmd.com/read/34246460/changes-in-pulse-pressure-variation-to-assess-preload-responsiveness-in-mechanically-ventilated-patients-with-spontaneous-breathing-activity-an-observational-study
#14
Olfa Hamzaoui, Rui Shi, Simone Carelli, Benjamin Sztrymf, Dominique Prat, Frederic Jacobs, Xavier Monnet, Corentin Gouëzel, Jean-Louis Teboul
BACKGROUND: Pulse pressure variation (PPV) is not reliable in predicting preload responsiveness in patients receiving mechanical with spontaneous breathing (SB) activity. We hypothesised that an increase in PPV after a tidal volume (VT ) challenge (TVC) or a decrease in PPV during passive leg raising (PLR) can predict preload responsiveness in such cases. METHODS: This prospective observational study was performed in two ICUs and included patients receiving mechanical ventilation with SB, for whom the treating physician decided to test preload responsiveness...
July 8, 2021: British Journal of Anaesthesia
https://read.qxmd.com/read/34246462/perioperative-fluid-balance-and-its-relationship-with-patient-outcomes-comment-on-br-j-anaesth-2021-126-720-9
#15
LETTER
Catherine Yarr, Usha Gurunathan
No abstract text is available yet for this article.
July 7, 2021: British Journal of Anaesthesia
https://read.qxmd.com/read/34246459/association-between-postoperative-delirium-and-cerebral-oxygen-desaturation-in-older-patients-undergoing-cardiac-surgery-comment-on-br-j-anaesth-2020-124-146-53
#16
LETTER
Fu S Xue, Shao H Liu, Hai J Hou
No abstract text is available yet for this article.
July 7, 2021: British Journal of Anaesthesia
https://read.qxmd.com/read/34243942/dales-drug-allergy-labels-in-elective-surgical-patients-a-prospective-multicentre-cross-sectional-study-of-incidence-risks-and-attitudes-in-penicillin-de-labelling-strategies
#17
Caroline Thomas, Sam Clark, David Fallaha, Michelle Wilson, Philip M Hopkins, Sinisa Savic, Louise Savic
BACKGROUND: We sought to define the prevalence and nature of patient-reported drug allergies, determine their impact on prescribing, and explore drug allergy knowledge and attitudes amongst anaesthetists. METHODS: We performed a prospective cross-sectional study in 213 UK hospitals in 2018. Elective surgical patients were interviewed, with a detailed allergy history taken in those self-reporting drug allergy. Anaesthetists completed a questionnaire concerning perioperative drug allergy...
July 6, 2021: British Journal of Anaesthesia
https://read.qxmd.com/read/34243941/an-integrative-review-of-method-types-used-in-the-study-of-medication-error-during-anaesthesia-implications-for-estimating-incidence
#18
REVIEW
Ravinder Bratch, Jaideep J Pandit
To meet the WHO vision of reducing medication errors by 50%, it is essential to know the current error rate. We undertook an integrative review of the literature, using a systematic search strategy. We included studies that provided an estimate of error rate (i.e. both numerator and denominator data), regardless of type of study (e.g. RCT or observational study). Under each method type, we categorised the error rate by type, by classification used by the primary studies (e.g. wrong drug, wrong dose, wrong time), and then pooled numerator and denominator data across studies to obtain an aggregate error rate for each method type...
July 6, 2021: British Journal of Anaesthesia
https://read.qxmd.com/read/34243940/effect-of-electroencephalogram-guided-anaesthesia-administration-on-1-yr-mortality-1-yr-follow-up-of-a-randomised-clinical-trial
#19
Bradley A Fritz, Christopher R King, Angela M Mickle, Troy S Wildes, Thaddeus P Budelier, Jordan Oberhaus, Daniel Park, Hannah R Maybrier, Arbi Ben Abdallah, Alex Kronzer, Sherry L McKinnon, Brian A Torres, Thomas J Graetz, Daniel A Emmert, Ben J Palanca, Tracey W Stevens, Susan L Stark, Eric J Lenze, Michael S Avidan
BACKGROUND: Intraoperative EEG suppression duration has been associated with postoperative delirium and mortality. In a clinical trial testing anaesthesia titration to avoid EEG suppression, the intervention did not decrease the incidence of postoperative delirium, but was associated with reduced 30 day mortality. The present study evaluated whether the EEG-guided anaesthesia intervention continued to be associated with reduced 1 yr mortality. METHODS: This manuscript reports 1 yr follow-up of patients from a single-centre RCT, including a post-hoc secondary outcome (1 yr mortality) in addition to pre-specified secondary outcomes...
July 6, 2021: British Journal of Anaesthesia
https://read.qxmd.com/read/34238549/the-evolution-of-methods-to-estimate-the-rate-of-medication-error-in-anaesthesia
#20
EDITORIAL
Craig S Webster
No abstract text is available yet for this article.
July 5, 2021: British Journal of Anaesthesia
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