Clinical and Experimental Dermatology

No abstract text is available yet for this article.

No abstract text is available yet for this article.

Epidermal growth factor receptor inhibitors (EGFRIs) are widely used to treat various types of malignancies. One of the common adverse reactions is cutaneous toxicity, mostly presenting as acneiform eruptions, paronychia and xerosis. Erosive pustular dermatosis of the scalp (EPDS) is a rare cutaneous adverse reaction that develops during treatment with EGFRIs. The pathogenesis of EGFRI-induced EPDS is poorly understood. Here we present three cases of EPDS induced by EGFRIs. The proteins LTA4H (leukotriene A-4 hydrolase), METAP1 (methionine aminopeptidase 1), BID (BH3-interacting domain death agonist), SMAD1 (mothers against decapentaplegic homologue), PRKRA (interferon-inducible double-stranded RNA-dependent protein kinase activator A), YES1 (tyrosine-protein kinase Yes) and EGFL7 (epidermal growth factor-like protein 7) were significantly upregulated in EGFRI-stimulated peripheral blood mononuclear cell cultures, and validated in the lesions...

No abstract text is available yet for this article.

No abstract text is available yet for this article.

No abstract text is available yet for this article.

No abstract text is available yet for this article.

BACKGROUND: Atopic dermatitis (AD) is one of the most common chronic inflammatory skin disease. The effect of probiotic administration on the severity of adult patients with AD have shown inconsistent results. We aimed to determine the effectiveness of probiotic supplementation as a therapeutic tool for adult AD. METHODS: PubMed, Scopus, and EMBASE were systematically queried to collect data from studies in which probiotics were administered to treat adult AD. RESULTS: Out of 413 publications, 9 papers were included in the meta-analysis...

No abstract text is available yet for this article.

Atopic dermatitis (AD) is associated with high levels of psychosocial burden, often resulting in poor mental health outcomes. Despite this association, few studies have evaluated the efficacy of mental health interventions within this population. Utilization of multidisciplinary and peer-led support in addition to equipping patients with psychological tools may be beneficial in improving mental health outcomes. Future research is needed to determine which interventions and formats are desired, effective, and accessible among patients and caregivers with AD...

No abstract text is available yet for this article.

14-22.3% of patients undergoing skin surgery take an anti-thrombotic medication, with more patients now taking Direct Oral Anticoagulants (DOACs). Latest evidence suggests the risk of stopping DOACs peri-operatively is low in skin surgery, particularly for primary closures, but remains unclear for more complex procedures. The 2016 British Society for Dermatological Surgery (BSDS) guidance suggested consideration of stopping DOACS for 24-48 hours based on individual bleeding risk. We developed an online survey of BSDS members to better understand clinical practice and guideline adherence with a view to updating the guidance...

No abstract text is available yet for this article.

No abstract text is available yet for this article.

No abstract text is available yet for this article.

No abstract text is available yet for this article.

No abstract text is available yet for this article.

No abstract text is available yet for this article.

No abstract text is available yet for this article.

No abstract text is available yet for this article.