journal
Journals Clinical and Experimental Derm...

Clinical and Experimental Dermatology

https://read.qxmd.com/read/37171041/a-21-year-old-female-with-progressive-asymptomatic-skin-laxity-in-flexural-regions
#21
JOURNAL ARTICLE
Thilo Gambichler, Sabine Hoffjan, Mato Nagel, Meike Terschlüsen, Rita Mansour, Lina Würfel, Klaus Hoffmann, Laura Susok, Heinrich Dickel, Martin Doerler
No abstract text is available yet for this article.
May 12, 2023: Clinical and Experimental Dermatology
https://read.qxmd.com/read/37171025/low-grade-cutaneous-immune-related-adverse-events-leading-to-immunotherapy-discontinuation
#22
JOURNAL ARTICLE
Ted V Jacoby, Maria S Asdourian, Nishi Shah, Tracey S Otto, Leah L Thompson, Kerry L Reynolds, Steven T Chen
No abstract text is available yet for this article.
May 12, 2023: Clinical and Experimental Dermatology
https://read.qxmd.com/read/37162010/efficacy-of-chemotherapies-for-unresectable-extramammary-paget-disease-a-single-centre-retrospective-study
#23
JOURNAL ARTICLE
Shogo Wada, Dai Ogata, Eiji Nakano, Kenjiro Namikawa, Naoya Yamazaki
BACKGROUND: Extramammary Paget disease (EMPD) is a cutaneous neoplasm that can metastasise to the lymph nodes and distant organs, resulting in a poor prognosis. For unresectable distant metastases of EMPD, no consensus has been reached regarding the optimal chemotherapy owing to the lack of data. OBJECTIVES: To evaluate the efficacy of three regimens, docetaxel (DTX) monotherapy, combination therapy with 5-fluorouracil, epirubicin, carboplatin, vincristine, and mitomycin C (FECOM), and tegafur (S-1) monotherapy...
May 10, 2023: Clinical and Experimental Dermatology
https://read.qxmd.com/read/37155594/gamified-learning-in-dermatology-and-dermoscopy-education-a-paradigm-shift
#24
JOURNAL ARTICLE
Francisca Donoso, Dominga Peirano, Caterina Longo, Zoe Apalla, Aimilios Lallas, Natalia Jaimes, Cristian Navarrete-Dechent
Teaching methods in medical education have been changing. More recent teaching modalities go beyond the traditional delivery of knowledge, promoting learning motivation and improving teaching and learning outcomes. For example, "gamification" and "serious games" are methodologies that use the principles of games to facilitate learning processes and the acquisition of skills and knowledge, thereby improving the attitude towards learning when compared to traditional teaching methods. Since dermatology is a visual field, images are a key component of different teaching strategies...
May 8, 2023: Clinical and Experimental Dermatology
https://read.qxmd.com/read/37151115/pitted-keratolysis
#25
JOURNAL ARTICLE
Vijayasankar Palaniappan, Aravind Baskar Murthy, Kaliaperumal Karthikeyan
Pitted keratolysis (PK) is a common superficial bacterial skin infection confined to the stratum corneum. It is clinically characterized by multifocal, discrete, pits or crater-like punched-out lesions, commonly over the pressure-bearing aspects of the foot. It is asymptomatic and associated with malodor. The surface is often moist and macerated. The diagnosis of PK is often clinical and unnecessary diagnostic procedures are not warranted. Lifestyle modifications form the cornerstone of the management of PK...
May 8, 2023: Clinical and Experimental Dermatology
https://read.qxmd.com/read/37151044/screening-for-hepatic-fibrosis-in-psoriasis-patients-prescribed-methotrexate-can-we-make-a-change
#26
JOURNAL ARTICLE
Daniel Lyons, Grainne Callaghan, Gregg Murray, John Ryan, Muireann Roche
No abstract text is available yet for this article.
May 8, 2023: Clinical and Experimental Dermatology
https://read.qxmd.com/read/37146159/successful-treatment-of-field-of-cancerization-in-the-dorsum-of-the-hands-with-1-tirbanibulin-ointment
#27
JOURNAL ARTICLE
Carlos Abril-Pérez, Mansilla-Polo Miguel, Daniel Martin-Torregrosa, Rafael Botella-Estrada
No abstract text is available yet for this article.
May 5, 2023: Clinical and Experimental Dermatology
https://read.qxmd.com/read/37146158/sarilumab-interleukin-6-receptor-monoclonal-antibody-for-the-treatment-of-pemphigus-vulgaris
#28
JOURNAL ARTICLE
Kashini Andrew, Sukhjit K Dhariwal, Weronika Szczecinska
No abstract text is available yet for this article.
May 5, 2023: Clinical and Experimental Dermatology
https://read.qxmd.com/read/37140446/a-novel-compound-heterozygous-variant-in-the-lls-gene-is-associated-with-non-syndromic-hypotrichosis
#29
JOURNAL ARTICLE
Fanny Morice-Picard, Pierre-Louis Lanvin, Eulalie Lasseaux, Franck Boralevi, Christine Labrèze, Louis Lebreton
No abstract text is available yet for this article.
May 4, 2023: Clinical and Experimental Dermatology
https://read.qxmd.com/read/37140444/plack-syndrome-caused-by-novel-pathogenic-variants-in-cast-a-case-report-and-literature-review
#30
JOURNAL ARTICLE
Bin Hu, Zhuoqing Gong, Sha Peng, Huijin Wang, Liuqing Chen, Zhimiao Lin
No abstract text is available yet for this article.
May 4, 2023: Clinical and Experimental Dermatology
https://read.qxmd.com/read/37140442/primary-cutaneous-lymphomas-exploration-of-10-year-data-at-a-supra-regional-mdt-in-glasgow-uk
#31
JOURNAL ARTICLE
Sarah McCusker, Ivy Ngu
Primary cutaneous lymphomas (PCL) are non-Hodgkin lymphomas, presenting in the skin. They are classified into cutaneous B-cell (CBCL), or cutaneous T-cell lymphomas (CTCL), the latter being the most common. The most common CTCL subtypes are mycosis fungoides (MF) and Sézary syndrome (SS).1 All cases should be discussed at a specialist multidisciplinary team (MDT) meeting.2 This report is the first published review of PCL MDT case discussion in the UK. Cases from the supra-regional specialist cutaneous lymphoma MDT in Glasgow, between 2008 and 2019, were reviewed...
May 4, 2023: Clinical and Experimental Dermatology
https://read.qxmd.com/read/37140426/efficacy-and-safety-of-supramolecular-active-zinc-in-the-treatment-of-scalp-psoriasis-a-multicenter-randomized-observed-blind-parallel-group-placebo-and-active-controlled-non-inferiority-trial
#32
JOURNAL ARTICLE
Chen Yu, Nan Yu, Xian Jiang, Xinghua Gao, Shichao Lv, Gang Wang
BACKGROUND: Controlling the relapses of scalp psoriasis is a clinical issue. OBJECTIVE: To evaluate the efficacy and safety of a supramolecular active zinc (Zn) anti-dandruff hair conditioner in managing scalp psoriasis (SP). METHODS: This multicenter, randomized, observed-blind, parallel-group, placebo- and active-controlled non-inferiority trial enrolled 211 patients with SP between October 2018 and June 2019. The participants were randomized 1:1:1 to the experimental (supramolecular active Zn anti-dandruff hair conditioner), placebo (supramolecular hydrogel), or positive control (calcipotriol liniment) group...
May 4, 2023: Clinical and Experimental Dermatology
https://read.qxmd.com/read/37130096/do-temperature-changes-cause-eczema-flares-an-english-cohort-study
#33
JOURNAL ARTICLE
Jonathan Chan, Stephanie J MacNeill, Beth Stuart, Y T Eunice Lo, Amanda Roberts, Dann Mitchell, Matthew J Ridd
BACKGROUND: It is unclear if ambient temperature changes affect eczema. It is also unclear if people with worse disease are more susceptible to weather-related flares, or specific types of emollient offer protection. Substantiating these links may help inform action plans and patients self-management. OBJECTIVE: To investigate the effect of short-term temperature variations on eczema symptoms in children. METHODS: Data from a UK cohort of 519 children (6 months-12 years) with at least mild eczema, participating in a randomised trial comparing four types of emollients on eczema symptoms, were combined with observed temperature data from the Hadley Centre's Integrated Surface Database...
May 2, 2023: Clinical and Experimental Dermatology
https://read.qxmd.com/read/37130084/lichen-planus-like-rash-in-a-black-patient
#34
JOURNAL ARTICLE
Mikkel B Jensen, Pia W Staun, Saman Salim, Mathias T Svendsen
No abstract text is available yet for this article.
May 2, 2023: Clinical and Experimental Dermatology
https://read.qxmd.com/read/37127912/cutaneous-sarcoma-a-review-and-practical-approach-to-management
#35
JOURNAL ARTICLE
Sophie Stoneham, Alys Hunter, Mina Raahimi, Amy Livesey, Charles D Mitchell, Stephen Keohane
Sarcomas arising in the skin are rare but potentially fatal. These tumours originate from mesenchymal cells and can be divided between those that arise in soft tissue and those arising from bone. General guidelines exist for the management of soft tissue sarcomas however there are no specific guidelines for cutaneous sarcomas. Current literature was reviewed for management of seven cutaneous sarcomas including atypical fibroxanthoma (AFX), pleomorphic dermal sarcoma (PDS), dermal and subcutaneous leiomyosarcoma (LMS), dermatofibroma sarcoma protuberans (DFDP), Kaposi's sarcoma (KS), cutaneous angiosarcoma (CAS) and malignant peripheral nerve sheath tumour (MPNST)...
May 2, 2023: Clinical and Experimental Dermatology
https://read.qxmd.com/read/37119282/topical-steroid-withdrawal-an-emerging-clinical-problem
#36
JOURNAL ARTICLE
Tenzin Sung-Rab Brookes, Richard Barlow, Padma Mohandas, Anthony Bewley
BACKGROUND: Topical steroid withdrawal (TSW) is a newly described disease characterised by erythema and burning following discontinuation of prolonged use of mid- to high-potency topical corticosteroids. No consensus diagnostic criterion exists. TSW is frequently interpreted as flaring of the underlying disorder or contact allergy to topical treatment. OBJECTIVES: To better characterise TSW symptomatology, detail our experience with management, and assess the proportion of patients who pursue nonconventional management...
April 29, 2023: Clinical and Experimental Dermatology
https://read.qxmd.com/read/37119274/how-to-critically-appraise-a-systematic-review-an-aide-for-the-reader-and-reviewer
#37
JOURNAL ARTICLE
John Frewen, Marianne de Brito, Anjali Pathak, Richard Barlow, Hywel C Williams
The number of published systematic reviews has soared rapidly in recent years. Sadly, the quality of most systematic reviews in dermatology is substandard. With the continued increase in exposure to systematic reviews, and their potential to influence clinical practice, we sought to describe a sequence of useful tips for the busy clinician reader to determine study quality and clinical utility. Important factors to consider when assessing systematic reviews include: determining the motivation to performing the study, establishing if the study protocol was pre-published, assessing quality of reporting using the PRISMA checklist, assessing study quality using the AMSTAR-2 critical appraisal checklist, assessing for evidence of spin, and summarising the main strengths and limitations of the study to determine if it could change clinical practice...
April 29, 2023: Clinical and Experimental Dermatology
https://read.qxmd.com/read/37119273/environmental-and-economic-considerations-for-diagnostic-biopsies-in-basal-cell-carcinomas
#38
JOURNAL ARTICLE
Usamah M Afzal, Faisal R Ali
No abstract text is available yet for this article.
April 29, 2023: Clinical and Experimental Dermatology
https://read.qxmd.com/read/37119266/pembrolizumab-associated-expansion-of-radiation-induced-morphea-responsive-to-dupilumab-a-case-report
#39
JOURNAL ARTICLE
Jordan T Said, Christopher Iriarte, Jordan Talia, Bonnie Leung, Cesar A Virgen, Matthew Robertson, Michael S Rabin, Cecilia Larocca, Nicole R LeBoeuf
Radiation-induced morphea (RIM) is a rare but distinctive inflammatory complication of therapeutic radiation.1 It most commonly presents as painful sclerosis of the epidermis and dermis limited to the irradiated field. Morphea has also been reported as an immune-related adverse event (irAE) induced by anti-programmed death-1 (PD-1) immune checkpoint inhibitors (ICIs).2,3 We report a patient who first received local radiation therapy to the thorax for lung adenocarcinoma that was complicated by RIM. The patient's morphea then progressed widely beyond the irradiated field in the setting of pembrolizumab therapy...
April 29, 2023: Clinical and Experimental Dermatology
https://read.qxmd.com/read/37119261/atopic-dermatitis-in-skin-of-colour-part-2-considerations-in-clinical-presentation-and-treatment-options
#40
JOURNAL ARTICLE
Christian Gan, Satveer Mahil, Andrew Pink, Michelle Rodrigues
Recent advances in atopic dermatitis (AD) present the condition as a heterogenous disease of distinct endotypes across ethnic groups. AD in people with skin of colour may appear psoriasiform, lichenoid, scaly, or papular, with a violaceous colour and there is a higher prevalence of post-inflammatory dyspigmentation compared to affected individuals of Caucasian ethnicity. These differences in clinical presentation may limit the use of AD assessment tools in people with skin of colour, leading to potential for misdiagnosis and underestimation of severity, particularly in relation to assessment of erythema...
April 29, 2023: Clinical and Experimental Dermatology
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