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Bcl11b and Atoh8 Coordinate Cellular Plasticity for Reprogramming and Transformation.
Cellular Reprogramming 2022 November 22
By dissecting and comparing the transcriptional trajectories and epigenomic traits of reprogramming and transforming cells at the single-cell resolution, Huyghe et al discovered Bcl11b and Atoh8, two key transcription factors controlling cell plasticity during pluripotent reprogramming and oncogenic transformation.
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