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A Retrospective Study on Alopecia Areata in Children: Clinical Characteristics and Treatment Choices.
Skin Appendage Disorders 2021 November
BACKGROUND: Although children are affected frequently with alopecia areata (AA), data are limited on clinical characteristics and treatment choices.
MATERIALS AND METHODS: We retrospectively reviewed the records of the pediatric dermatology department over a 12-year period to identify children with AA. Clinical data were collected.
RESULTS: Three hundred and sixty-four children with AA were identified, aged 1-12 years, 214 males and 150 females. The mean age of onset was 6.6 years (±3.3). The disease presented with patches on the scalp in the majority (90.7%), whereas only 6 children had alopecia totalis or universalis. The most commonly prescribed treatment was topical steroids (69.1%), followed by the combination of topical steroids and minoxidil 2% (14.3%). Oral steroids were prescribed in only 16 children. Follow-up at 3 months was available for only 70 children and the majority (84.3%) had some hair regrowth. Hair regrowth was unrelated to the number of plaques ( p = 0.257), disease location ( p = 0.302), and atopy ( p = 0.999). Hair regrowth only correlated with the type of treatment ( p = 0.003) with potent topical and intralesional steroids giving the best results.
CONCLUSION: AA usually presents with a mild form in children, and potent topical steroids are the mainstay of treatment.
MATERIALS AND METHODS: We retrospectively reviewed the records of the pediatric dermatology department over a 12-year period to identify children with AA. Clinical data were collected.
RESULTS: Three hundred and sixty-four children with AA were identified, aged 1-12 years, 214 males and 150 females. The mean age of onset was 6.6 years (±3.3). The disease presented with patches on the scalp in the majority (90.7%), whereas only 6 children had alopecia totalis or universalis. The most commonly prescribed treatment was topical steroids (69.1%), followed by the combination of topical steroids and minoxidil 2% (14.3%). Oral steroids were prescribed in only 16 children. Follow-up at 3 months was available for only 70 children and the majority (84.3%) had some hair regrowth. Hair regrowth was unrelated to the number of plaques ( p = 0.257), disease location ( p = 0.302), and atopy ( p = 0.999). Hair regrowth only correlated with the type of treatment ( p = 0.003) with potent topical and intralesional steroids giving the best results.
CONCLUSION: AA usually presents with a mild form in children, and potent topical steroids are the mainstay of treatment.
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