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Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Erythropoietin and Brain Magnetic Resonance Imaging Findings in Hypoxic-Ischemic Encephalopathy: Volume of Acute Brain Injury and 1-Year Neurodevelopmental Outcome.
Journal of Pediatrics 2017 July
In the Neonatal Erythropoietin and Therapeutic Hypothermia Outcomes study, 9/20 erythropoietin-treated vs 12/24 placebo-treated infants with hypoxic-ischemic encephalopathy had acute brain injury. Among infants with acute brain injury, the injury volume was lower in the erythropoietin than the placebo group (P = .004). Higher injury volume correlated with lower 12-month neurodevelopmental scores.
TRIAL REGISTRATION: ClinicalTrials.gov: NCT01913340.
TRIAL REGISTRATION: ClinicalTrials.gov: NCT01913340.
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