journal
https://read.qxmd.com/read/38610920/impaired-carbohydrate-metabolism-among-women-with-chronic-low-back-pain-and-the-role-of-dietary-carbohydrates-a-randomized-controlled-cross-over-experiment
#1
JOURNAL ARTICLE
Ömer Elma, Sevilay Tümkaya Yılmaz, Jo Nijs, Peter Clarys, Iris Coppieters, Evelien Mertens, Anneleen Malfliet, Tom Deliens
Background: Impaired glucose regulation is suggested to be related to chronic low back pain (CLBP), although it is not clear how they interact with each other. Thus, the primary aim of this study was to investigate differences in postprandial glycemic responses (PPGRs) (the first sign of impaired glucose metabolism) to high- (sucrose) and low-glycemic index (GI) (isomaltulose) beverages in normoglycemic women with CLBP and healthy controls (HCs) and explore whether any group that showed greater PPGRs to high-GI beverage intake would benefit when the high-GI beverage was replaced with a low-GI beverage...
April 8, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38610919/an-international-multidisciplinary-consensus-set-of-patient-centered-outcome-measures-for-substance-related-and-addictive-disorders
#2
JOURNAL ARTICLE
Nicola Black, Sophie Chung, Calvert Tisdale, Luz Sousa Fialho, Apinun Aramrattana, Sawitri Assanangkornchai, Alex Blaszczynski, Henrietta Bowden-Jones, Wim van den Brink, Adrian Brown, Qiana L Brown, Linda B Cottler, Maury Elsasser, Marica Ferri, Maria Florence, Ralitza Gueorguieva, Ryan Hampton, Suzie Hudson, Peter J Kelly, Nicholas Lintzeris, Lynette Murphy, Abhijit Nadkarni, Joanne Neale, Daniel Rosen, Hans-Jürgen Rumpf, Brian Rush, Gabriel Segal, Gillian W Shorter, Marta Torrens, Christopher Wait, Katherine Young, Michael Farrell
Background: In 1990, the United States' Institute of Medicine promoted the principles of outcomes monitoring in the alcohol and other drugs treatment field to improve the evidence synthesis and quality of research. While various national outcome measures have been developed and employed, no global consensus on standard measurement has been agreed for addiction. It is thus timely to build an international consensus. Convened by the International Consortium for Health Outcomes Measurement (ICHOM), an international, multi-disciplinary working group reviewed the existing literature and reached consensus for a globally applicable minimum set of outcome measures for people who seek treatment for addiction...
April 8, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38610918/impaired-hand-grip-strength-correlates-with-greater-disability-and-symptom-severity-in-post-covid-myalgic-encephalomyelitis-chronic-fatigue-syndrome
#3
JOURNAL ARTICLE
Anna Paffrath, Laura Kim, Claudia Kedor, Elisa Stein, Rebekka Rust, Helma Freitag, Uta Hoppmann, Leif G Hanitsch, Judith Bellmann-Strobl, Kirsten Wittke, Carmen Scheibenbogen, Franziska Sotzny
Background: Post-COVID syndrome (PCS) encompasses a diverse array of symptoms persisting beyond 3 months after acute SARS-CoV-2 infection, with mental as well as physical fatigue being the most frequent manifestations. Methods: In 144 female patients with PCS, hand grip strength (HGS) parameters were assessed as an objective measure of muscle fatigue, with 78 meeting the Canadian Consensus Criteria for postinfectious myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). The severity of disability and key symptoms was evaluated using self-reported questionnaires...
April 8, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38610917/rationale-for-using-high-frequency-ultrasound-as-a-routine-examination-in-skin-cancer-surgery-a-practical-approach
#4
REVIEW
Diana Crisan, Evelyne Tarnowietzki, Lukas Bernhard, Melina Möller, Karin Scharffetter-Kochanek, Maria Crisan, Lars Alexander Schneider
Ultrasound and high-frequency ultrasound assessment of melanoma and non-melanoma skin cancer in the pre-therapeutical setting is becoming increasingly popular in the field of dermatosurgery and dermatooncology, as it can provide clinicians with relevant, "in vivo" parameters regarding tumor lateral and depth extension as well as potential locoregional spread, cancelling the need of more extensive imaging methods and avoiding a delay in diagnosis. Furthermore, preoperative sonography and color Doppler can aid in orienting the clinical diagnosis, being able in numerous situations to differentiate between benign and malignant lesions, which require a different therapeutic approach...
April 8, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38610916/efficacy-of-trimetazidine-in-the-prevention-of-contrast-induced-nephropathy-in-patients-undergoing-contrast-coronary-intervention-a-systematic-review-and-meta-analysis-prisma
#5
REVIEW
Tiny Nair, Saumitra Ray, Jacob George, Arindam Pande
Objective : The present systematic review assessed the efficacy of peri-procedurally administered trimetazidine in the prevention of contrast-induced nephropathy (CIN) in patients undergoing coronary interventions with contrast agents. Methods : We performed a systematic literature review of articles published in PubMed and Google Scholar by 7 December 2023 and included articles from the last 15 years that evaluated the efficacy of trimetazidine in preventing CIN in cardiac patients undergoing coronary intervention...
April 8, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38610915/association-of-obesity-with-telomere-length-in-human-sperm
#6
JOURNAL ARTICLE
Efthalia Moustakli, Athanasios Zikopoulos, Charikleia Skentou, Stefanos Dafopoulos, Sofoklis Stavros, Konstantinos Dafopoulos, Peter Drakakis, Ioannis Georgiou, Athanasios Zachariou
Background: Telomere attrition and mitochondrial dysfunction are two fundamental aspects of aging. Calorie restriction (CR) is the best strategy to postpone aging since it can enhance telomere attrition, boost antioxidant capacity, and lower the generation of reactive oxygen species (ROS). Since ROS is produced by mitochondria and can readily travel to cell nuclei, it is thought to be a crucial molecule for information transfer between mitochondria and cell nuclei. Important variables that affect the quality and functionality of sperm and may affect male reproductive health and fertility include telomere length, mitochondrial content, and the ratio of mitochondrial DNA (mtDNA) to nuclear DNA (nDNA)...
April 8, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38610914/two-methods-of-forward-head-posture-assessment-radiography-vs-posture-and-their-clinical-comparison
#7
JOURNAL ARTICLE
Paul A Oakley, Ibrahim M Moustafa, Jason W Haas, Joseph W Betz, Deed E Harrison
Background: Forward head posture (FHP) and altered cervical lordotic curvatures are common spine displacements often associated with neck pain and disability. Two primary categories for determining FHP exist: radiographic and postural measurements. Methods: This study investigated the correlation between the craniovertebral angle (CVA), the radiographically measured C2-C7 sagittal vertical axis (SVA), and cervical lordosis (absolute rotation angle: ARA C2-C7) in a sample of participants with chronic myofascial pain (CMP)...
April 8, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38610913/assessment-of-changes-in-cap-and-residual-stromal-thickness-values-during-a-6-month-observation-after-refractive-lenticule-extraction-small-incision-lenticule-extraction
#8
JOURNAL ARTICLE
Dominika Janiszewska-Bil, Barbara Czarnota-Nowakowska, Izabela Kuciel-Polczak, Dariusz Dobrowolski, Beniamin Oskar Grabarek, Anita Lyssek-Boroń, Edward Wylęgała, Joanna Wierzbowska
Background : In this study, the changes in corneal cap and residual stromal thickness (RST) values during a 180-day observation period after refractive lenticule extraction small incision lenticule extraction (ReLEx SMILE) were assessed. Methods: Fifty patients underwent ReLEx SMILE using the VisuMax 500 femtosecond laser, with corneal imaging conducted pre and post procedure via anterior segment optical coherence tomography (AS-OCT). Cap thickness in the center and 1.5 mm from the center in four meridians was measured at various intervals...
April 8, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38610912/immunomodulation-driven-by-theranova-filter-during-a-single-hd-session
#9
JOURNAL ARTICLE
Carlotta Caprara, Grazia Maria Virzì, Katia Chieregato, Nicola Marchionna, Valentina Corradi, Alessandra Brendolan, Claudio Ronco, Monica Zanella
Background : Patients with end-stage kidney disease (ESKD) have altered immunity. Patients on hemodialysis (HD) present a coexistence of immunodeficiency and activation of the immune system. We evaluated the immunophenotypic profile induced by the medium cut-off of Theranova filter during a single HD session in the same individual. Methods : This pilot observational study explored 11 patients (75 ± 8 years and 73% male). Blood samples were collected prior to (predialytic, PRE) and after 4 h (postdialytic, POST) standard HD session with a medium cut-off, polyarylethersulfone and polyvinylpyrrolidone blend, BPA-free membrane...
April 8, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38610911/the-contribution-of-proteomics-in-understanding-endometrial-protein-expression-in-women-with-recurrent-implantation-failure
#10
REVIEW
Anastasios Potiris, Eleni Alyfanti, Eirini Drakaki, Despoina Mavrogianni, Theodoros Karampitsakos, Pavlos Machairoudias, Spyridon Topis, Athanasios Zikopoulos, Chara Skentou, Periklis Panagopoulos, Peter Drakakis, Sofoklis Stavros
Recurrent implantation failure (RIF) poses a significant challenge in assisted reproductive technology (ART) outcomes. The endometrium plays a crucial role in embryo implantation, and its protein expression profile is integral in determining receptivity. Proteomics has emerged as a valuable tool in unraveling the molecular intricacies underlying endometrial receptivity and RIF. The aim of the present review is to analyze the contribution of proteomics to the understanding of endometrial protein expression in women with RIF, based on the results of significant proteomic studies...
April 8, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38610910/the-impact-of-tumor-laterality-unilateral-vs-bilateral-on-presentation-and-management-outcome-in-patients-with-retinoblastoma
#11
JOURNAL ARTICLE
Mona Mohammad, Mustafa Mehyar, Hadeel Halalsheh, Reham Shehada, Omar Al Adawi, Jakub Khzouz, Imad Jaradat, Maysa Al-Hussaini, Iyad Sultan, Ibrahim Alnawaiseh, Yacoub A Yousef
Background: This study compares the outcomes of managing retinoblastoma between patients with unilateral and bilateral presentations. Methods: The study, conducted at the King Hussein Cancer Center in Amman, Jordan, retrospectively analyzed cases of retinoblastoma treated between March 2003 and December 2019. Evaluation criteria included clinical features, disease stage, treatment methods, and overall management outcomes. Results: The study comprised 697 eyes from 478 patients with retinoblastoma, with 52% being males...
April 8, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38610909/review-of-temperature-management-in-traumatic-brain-injuries
#12
REVIEW
Kenya Kawakita, Hajime Shishido, Yasuhiro Kuroda
Therapeutic hypothermia (TH) for severe traumatic brain injury has seen restricted application due to the outcomes of randomized controlled trials (RCTs) conducted since 2000. In contrast with earlier RCTs, recent trials have implemented active normothermia management in control groups, ensuring comparable intensities of non-temperature-related therapeutic interventions, such as neurointensive care. This change in approach may be a contributing factor to the inability to establish the efficacy of TH. Currently, an active temperature management method using temperature control devices is termed "targeted temperature management (TTM)"...
April 8, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38610908/associations-between-sleep-disturbances-personality-traits-and-self-regulation-in-a-sample-of-healthy-adults
#13
JOURNAL ARTICLE
Ali Zakiei, Dena Sadeghi-Bahmani, Habibolah Khazaie, Zeinab Lorestani, Mohammad Sadeghi, Dariuosh Korani, Zeinab Sahraei, Saeid Komasi, Zeno Stanga, Annette B Brühl, Serge Brand
Background: Scientific evidence and everyday experience show that sleep disturbances and self-regulation as a proxy of stress reactivity are linked. Particular personality traits such as neuroticism, internalizing and externalizing problems are also associated with sleep disturbances. Here, we combined self-regulation and personality traits and associated these variables with subjective sleep disturbances. Methods: A total of 846 adults (mean age: 33.7 years; 78.7% females) completed questionnaires covering sleep disturbances, self-regulation and personality traits...
April 8, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38610907/eyelid-skin-grafting-in-young-patients-with-facial-nerve-palsy
#14
JOURNAL ARTICLE
Yinon Shapira, Katja Ullrich, Sundas Masqood, Linda Okafor, Raman Malhotra
Background : The aim of this study is to report outcomes of eyelid full-thickness skin grafting augmentation in facial nerve palsy (FNP) patients younger than 50 years of age. Methods : In a retrospective, consecutive case series, nine eyelid skin grafts performed on eight FNP patients with skin contraction (five females; median age 42 years [range, 17-47]) are presented. In most cases, upper eyelid skin grafting was combined with levator recession and anterior lamellar repositioning. Lower eyelid skin grafting was combined with lower retractors recession in all cases...
April 8, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38610906/peripheral-arterial-disease-and-the-diabetic-foot-syndrome-neuropathy-makes-the-difference-a-narrative-review
#15
REVIEW
Gerhard Rümenapf, Nour Abilmona, Stephan Morbach, Martin Sigl
Background : In vascular medicine, peripheral arterial disease (PAD) and diabetic foot syndrome (DFS) are often considered synonymous with respect to the need for revascularization. In PAD patients, clinical symptoms reflect the degree of atherosclerotic disease, since peripheral innervation, including pain sensation, is not usually compromised. In DFS patients, however, symptoms of relevant foot ischemia are often absent and progression of ischemia goes unnoticed owing to diabetic polyneuropathy, the loss of nociception being the main trigger for foot ulcers...
April 8, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38610905/accumulation-of-microvascular-target-organ-damage-in-systemic-lupus-erythematosus-patients-is-associated-with-increased-cardiovascular-risk
#16
JOURNAL ARTICLE
Nikolaos Koletsos, Antonios Lazaridis, Areti Triantafyllou, Panagiota Anyfanti, Stamatina Lamprou, Anastasia Stoimeni, Nikolaos G Papadopoulos, Evaggelia-Evdoxia Koravou, Eugenia Gkaliagkousi
Background : Systemic lupus erythematosus (SLE) is a prototype autoimmune disease associated with increased cardiovascular (CV) burden. Besides increased arterial stiffness and subclinical atherosclerosis, microvascular dysfunction is considered an important component in the pathophysiology of CV disease. However, there is a lack of data regarding the effect of multiple target organ damage (TOD) on CV health. Objectives : This study aimed to evaluate (i) the presence of microvascular changes in SLE in various vascular beds, (ii) the possible associations between the accumulation of microvascular TOD and CV risk and (iii) whether Galectin-3 represents a predictor of combined microvascular TOD...
April 8, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38610904/acute-appendicitis-in-the-elderly-a-nationwide-retrospective-analysis
#17
JOURNAL ARTICLE
Malkiely Gal, Paran Maya, Kobo Ofer, Khan Mansoor, Abbou Benyamine, Kessel Boris
Background: Acute appendicitis (AA) in older individuals remains understudied. We aimed to assess AA characteristics in patients older than 60 years and evaluate the impact of comorbidities. Methods: This retrospective study analyzed data from the American National Inpatient Sample between 2016 and 2019 to compare AA characteristics in patients younger and older than 60 years. Results: Of the 538,400 patients included, 27.5% were older than 60 years. Younger patients had a higher appendectomy rate ( p < 0...
April 8, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38610903/trifecta-outcomes-of-robot-assisted-partial-nephrectomy-using-the-new-hugo%C3%A2-ras-system-versus-laparoscopic-partial-nephrectomy
#18
JOURNAL ARTICLE
Francesco Prata, Alberto Ragusa, Francesco Tedesco, Matteo Pira, Andrea Iannuzzi, Marco Fantozzi, Angelo Civitella, Roberto Mario Scarpa, Rocco Papalia
(1) Background : Laparoscopic partial nephrectomy (LPN) is still performed in many referred urological institutions, representing a valid alternative to robot-assisted partial nephrectomy (RAPN). We aimed to compare trifecta outcomes of LPN and RAPN with the Hugo™ RAS System. (2) Methods : Between October 2022 and September 2023, eighty-nine patients underwent minimally invasive partial nephrectomy (group A, RAPN = 27; group B, Laparoscopic PN = 62) for localized renal tumors at our Institution. Continuous variables were presented as median and IQR and compared by means of the Mann-Whitney U test, while categorical variables were presented as frequencies (%) and compared by means of the χ2 test...
April 7, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38610902/the-frontal-fibrosing-alopecia-treatment-dilemma
#19
REVIEW
Wiktoria Julia Krzesłowska, Anna Woźniacka
Frontal fibrosing alopecia (FFA) is a type of cicatricial alopecia predominantly observed in postmenopausal women, with the incidence rising since its initial description in 1994. The exact etiopathogenesis of the disease has not been completely elucidated. FFA is characterized by an inflammatory process affecting the hair follicles of the fronto-temporal hairline, leading to its gradual recession. Eyebrows, particularly the lateral parts, may also be affected. Early diagnosis and an implementation of effective therapy to limit the inflammatory process are crucial in halting disease progression...
April 7, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38610901/is-a-higher-amniotic-fluid-viral-load-associated-with-a-greater-risk-of-fetal-injury-in-congenital-cytomegalovirus-infection-a-systematic-review-and-meta-analysis
#20
REVIEW
Noa Gilad, Swati Agrawal, Eleni Philippopoulos, Kellie E Murphy, Shiri Shinar
Background : Numerous studies have aimed to predict prenatal and neonatal outcomes for pregnancies complicated by congenital cytomegalovirus (CMV). Presently, assessing CMV severity prenatally relies largely on fetal imaging. A controversy exists regarding CMV viral load (VL) and its association with fetal and neonatal sequelae. Objective : To perform a systematic review and meta-analysis investigating the association between CMV DNA VL in amniotic fluid and fetal and neonatal outcomes in pregnancies with congenital CMV...
April 7, 2024: Journal of Clinical Medicine
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