journal
https://read.qxmd.com/read/36675661/surgical-techniques-of-gastrojejunostomy-in-robotic-pancreatoduodenectomy-robot-sewn-versus-stapled-gastrojejunostomy-anastomosis
#1
JOURNAL ARTICLE
Kosei Takagi, Yuzo Umeda, Ryuichi Yoshida, Tomokazu Fuji, Kazuya Yasui, Jiro Kimura, Nanako Hata, Takahito Yagi, Toshiyoshi Fujiwara
BACKGROUND: Delayed gastric emptying (DGE) is a major complication of pancreatoduodenectomy (PD). Several efforts have been made to decrease the incidence of DGE. However, the optimal anastomotic method for gastro/duodenojejunostomy (GJ) remains debatable. Moreover, few studies have reported the impact of GJ surgical techniques on outcomes following robotic pancreatoduodenectomy (RPD). This study aimed to investigate the surgical outcomes of robot-sewn and stapled GJ anastomoses in RPD...
January 16, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/36675660/pre-transplant-total-lymphocyte-count-determines-anti-thymocyte-globulin-exposure-modifying-graft-versus-host-disease-incidence-and-post-transplant-thymic-restoration-a-single-center-retrospective-study
#2
JOURNAL ARTICLE
Antonio Giacomo Grasso, Roberto Simeone, Alessandra Maestro, Davide Zanon, Natalia Maximova
The use of anti-thymocyte globulin (ATG) as part of conditioning to prevent graft-versus-host disease (GVHD) may severely impair immune reconstitution (IR). We analyzed relationships between ATG exposure, the recipient lymphocyte count, IR, and transplant outcome. We retrospectively reviewed patients aged ≤ 18 years who underwent allogeneic HSCT between April 2005 and April 2020. The outcomes of interest included the incidence of GVHD, overall survival (OS), and IR. IR was analyzed through thymic magnetic resonance imaging (MRI) and by quantifying T CD4+ and recent thymic emigrants (RTEs)...
January 16, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/36675659/first-clinical-results-of-a-new-generation-of-ablative-solid-state-lasers
#3
Bojan Pajic, Brigitte Pajic-Eggspuehler, Zeljka Cvejic, Christian Rathjen, Viktor Ruff
In the early 2000s, solid-state lasers emerged as an alternative technology to excimer systems in refractive surgery. Despite some technological limits at the time, good clinical results could be achieved with solid-state laser systems. This prospective case series reports clinical outcomes of five eyes treated with a newly developed solid-state laser system (AquariuZ) in three patients. Patients underwent preoperative examination, including corneal topo-and tomography, aberrometry, and confocal microscopy...
January 16, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/36675658/favorable-prognosis-in-patients-with-recovered-pulmonary-hypertension-after-tavi-an-analysis-of-the-laplace-tavi-registry
#4
JOURNAL ARTICLE
Takuma Koike, Hiroshi Iwata, Yuichi Chikata, Shinichiro Doi, Ryo Naito, Hidetoshi Yasuda, Takehiro Funamizu, Hirohisa Endo, Sakiko Miyazaki, Shinya Okazaki, Ryosuke Higuchi, Itaru Takamisawa, Kei Sato, Harutoshi Tamura, Hiroaki Yokoyama, Tetsuya Tobaru, Shuichiro Takanashi, Minoru Tabata, Tohru Minamino
Pulmonary hypertension (PH) is a common complication of aortic stenosis (AS). Despite the established association between PH and poor outcomes in patients with AS, the prognostic implication of a change in PH after transcatheter aortic valve implantation (TAVI) has been rarely evaluated. This study analyzed a prospective multi-center TAVI registry database involving six Japanese centers and used the transtricuspid pressure gradient (TRPG) obtained by echocardiography to estimate pulmonary artery systolic pressure...
January 16, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/36675657/risk-factors-involved-in-the-high-incidence-of-bladder-cancer-in-an-industrialized-area-in-north-eastern-spain-a-case-control-study
#5
JOURNAL ARTICLE
José M Caballero, José M Gili, Juan C Pereira, Alba Gomáriz, Carlos Castillo, Montserrat Martín-Baranera
Bladder cancer (BC) is the most common of the malignancies affecting the urinary tract. Smoking and exposure to occupational and environmental carcinogens are responsible for most cases. Vallès Occidental is a highly industrialized area in north-eastern Spain with one of the highest incidences of BC in men. We carried out a case-control study in order to identify the specific risk factors involved in this area. Three hundred and six participants were included (153 cases BC and 153 controls matched for age and sex): in each group, 89...
January 16, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/36675656/resin-infiltration-of-non-cavitated-proximal-caries-lesions-in-primary-and-permanent-teeth-a-systematic-review-and-scenario-analysis-of-randomized-controlled-trials
#6
REVIEW
Marcus Cebula, Gerd Göstemeyer, Joachim Krois, Vinay Pitchika, Sebastian Paris, Falk Schwendicke, Susanne Effenberger
The present study aimed to meta-analyze and evaluate the certainty of evidence for resin infiltration of proximal carious lesions in primary and permanent teeth. While resin infiltration has been shown efficacious for caries management, the certainty of evidence remains unclear. The protocol was registered with PROSPERO (CRD42018080895), and PRISMA guidelines have been followed. The databases PubMed, Embase, and Cochrane CENTRAL were systematically screened, complemented by hand searches and cross-referencing...
January 16, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/36675655/web-based-nomograms-for-overall-survival-and-cancer-specific-survival-of-bladder-cancer-patients-with-bone-metastasis-a-retrospective-cohort-study-from-seer-database
#7
JOURNAL ARTICLE
Sheng Yang, Hongmin Zhou, Chaobo Feng, Ningze Xu, Yunshan Fan, Zhi Zhou, Yunfei Xu, Guoxin Fan, Xiang Liao, Shisheng He
BACKGROUND: Our study aimed to explore the prognostic factors of bladder cancer with bone metastasis (BCBM) and develop prediction models to predict the overall survival (OS) and cancer-specific survival (CSS) of BCBM patients. METHODS: A total of 1438 patients with BCBM were obtained from the SEER database. Patients from 2010 to 2016 were randomly divided into training and validation datasets (7:3), while patients from 2017 were divided for external testing. Nomograms were established using prognostic factors identified through Cox regression analyses and validated internally and externally...
January 16, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/36675654/lower-serum-uric-acid-levels-may-lower-the-incidence-of-diabetic-chronic-complications-in-u-s-adults-aged-40-and-over
#8
JOURNAL ARTICLE
Yingdong Han, Shuolin Wang, He Zhao, Yu Cao, Xinxin Han, Hong Di, Yue Yin, Juan Wu, Yun Zhang, Xuejun Zeng
Previous studies have generally reported the association between serum uric acid (SUA) and diabetic complications, but large-scale research exploring the above association in U.S. adults with diabetes is limited. To explore the association between SUA and chronic complications of diabetes among U.S. patients aged ≥40, we used data from the National Health and Nutrition Examination Survey 1999-2008. SUA was divided into three levels: T1 (SUA ≥ 420 μmol/L), T2 (300 ≤ SUA < 420 μmol/L), and T3 (SUA < 300 μmol/L)...
January 16, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/36675653/comparison-of-transperitoneal-and-retroperitoneal-robotic-partial-nephrectomy-for-patients-with-completely-lower-pole-renal-tumors
#9
JOURNAL ARTICLE
Wenlei Zhao, Yancai Ding, Dong Chen, Yundong Xuan, Zhiqiang Chen, Xupeng Zhao, Bin Jiang, Baojun Wang, Hongzhao Li, Chengliang Yin, Xin Ma, Gang Guo, Liangyou Gu, Xu Zhang
(1) Background: For completely lower pole renal tumors, we compared the perioperative outcomes of robotic partial nephrectomy via transperitoneal and retroperitoneal approaches. (2) Methods: Complete lower pole renal tumors were defined as tumors that received 1 point for the "L" element of the R.E.N.A.L. and located at the lower pole of kidney. After confirming consistency in baseline characteristics, oncological and functional benefits were compared. Pentafecta achievement was used to represent the perioperative optimal outcome, followed by multivariate analysis of factors associated with the lack of pentafecta achievement...
January 16, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/36675652/the-urine-calcium-creatinine-ratio-and-uricemia-during-hyponatremia-of-different-origins-clinical-implications
#10
JOURNAL ARTICLE
Guy Decaux, Wim Musch
BACKGROUND: Chronic hyponatremia is known to be associated with osteoporosis. It has been shown that chronic hyponatremia increases bone resorption in an attempt to release body stores of exchangeable sodium by different mechanisms. We wanted to know the calciuria of patients with hyponatremia of different origins. MATERIAL AND METHODS: We made a retrospective study of 114 consecutive patients with asymptomatic hyponatremia of different origins with the usual serum and urine chemistry...
January 16, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/36675651/the-value-of-the-first-clinical-impression-as-assessed-by-18-observations-in-patients-presenting-to-the-emergency-department
#11
JOURNAL ARTICLE
Thomas Tschoellitsch, Stefan Krummenacker, Martin W Dünser, Roland Stöger, Jens Meier
The first clinical impression of emergency patients conveys a myriad of information that has been incompletely elucidated. In this prospective, observational study, the value of the first clinical impression, assessed by 18 observations, to predict the need for timely medical attention, the need for hospital admission, and in-hospital mortality in 1506 adult patients presenting to the triage desk of an emergency department was determined. Machine learning models were used for statistical analysis. The first clinical impression could predict the need for timely medical attention [area under the receiver operating characteristic curve (AUC ROC), 0...
January 16, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/36675650/reliability-and-validity-of-non-instrumental-clinical-assessments-for-adults-with-oropharyngeal-dysphagia-a-systematic-review
#12
REVIEW
Reinie Cordier, Renée Speyer, Matthew Martinez, Lauren Parsons
This systematic review on non-instrumental clinical assessment in adult oropharyngeal dysphagia (OD) provides an overview of published measures with reported reliability and validity. In alignment with PRISMA, four databases (CINAHL, Embase, PsycINFO, and PubMed) were searched, resulting in a total of 16 measures and 32 psychometric studies included. The included measures assessed any aspect of swallowing, consisted of at least one specific subscale relating to swallowing, were developed by clinical observation, targeted adults, and were developed in English...
January 16, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/36675649/efficacy-and-safety-of-pulsed-field-ablation-in-atrial-fibrillation-a-systematic-review
#13
REVIEW
Jurgen Shtembari, Dhan Bahadur Shrestha, Bishnu Deep Pathak, Bishal Dhakal, Binit Upadhaya Regmi, Nimesh K Patel, Ghanshyam Palamaner Subash Shantha, Gautham Kalahasty, Karoly Kaszala, Jayanthi N Koneru
BACKGROUND: Atrial fibrillation (AF) is the most common cardiac arrhythmia associated with high morbidity and mortality. AF treatment is guided by a patient-provider risk-benefit discussion regarding drug versus ablation or combination. Thermal ablation has a high rate of adverse events compared to pulsed field ablation (PFA). In this systematic review, we aimed to determine the safety and efficacy of PFA. METHODS: The electronic search for relevant articles in English was completed in PubMed, PubMed Central, Cochrane library, Scopus, and Embase databases till July 2022...
January 16, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/36675648/advance-of-thrombolysis-and-thrombectomy-in-acute-ischemic-stroke
#14
EDITORIAL
Hyo Suk Nam, Byung Moon Kim
Globally, stroke remains the second leading cause of death, and the third-leading cause of death and disability, in the world [...].
January 16, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/36675647/dynamics-of-peripheral-blood-immune-cells-during-the-perioperative-period-after-digestive-system-resections-a-systematic-analysis-of-the-literature
#15
JOURNAL ARTICLE
Markus Bo Schoenberg, Yongsheng Han, Xiaokang Li, Xinyu Li, Julian Nikolaus Bucher, Nikolaus Börner, Dominik Koch, Markus Otto Guba, Jens Werner, Alexandr V Bazhin
An operation in itself is a kind of trauma and may lead to immunosuppression followed by a bounce back. Not many studies exist that describe dynamics of the distribution of peripheral blood (PB) immune cells during the perioperative period. Considering this scarcity, we aggregated the data on the dynamics of immune cells in patients with digestive system resections during the perioperative period and the relationship with short- and long-term prognoses. By the systematic retrieval of documents, we collected perioperative period data on white blood cells (WBC), lymphocytes, neutrophil-lymphocyte ratio (NLR), CD4+ T cells, CD8+ T cells, helper T cells (Th), B cells, natural killer cells (NK), dendritic cells (DCs), regulatory T cells (Tregs), regulatory B cells (Bregs), and Myeloid derived suppressor cells (MDSC)...
January 16, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/36675646/same-clinical-reality-of-spontaneous-rupture-of-the-common-iliac-artery-with-pseudoaneurysm-formation-comparison-of-two-therapeutical-solutions-endovascular-stent-graft-and-open-surgical-correction-for-two-cases-and-review-of-the-literature
#16
Horațiu Moldovan, Robert Tiganasu, Lucian Câlmâc, Cristian Voica, Marian Broască, Camelia Diaconu, Vlad Ichim, Mihai Cacoveanu, Liliana Mirea, Claudia Nica, Costin Minoiu, Irina Dobra, Daniela Gheorghiță, Lucian Dorobanțu, Adrian Molnar, Luminița Iliuță
The incidence of isolated iliac artery aneurysms is approximately 2% and common iliac artery pseudoaneurysms are even rarer. A pseudoaneurysm is a localized hemorrhage as opposed to an actual aneurysm, which affects the entire vascular wall. They are typically asymptomatic and only detectable accidentally while looking for other causes. If large and symptomatic, they typically exhibit pressure symptoms as a result of the compression of the structures around them. Common symptoms include generalized stomach pain, urological problems, gastrointestinal bleeding, and neurological symptoms such as leg paralysis or sciatica-like back pain...
January 16, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/36675645/chemotherapy-in-well-differentiated-neuroendocrine-tumors-net-g1-g2-and-g3-a-narrative-review
#17
REVIEW
Arianna Zappi, Irene Persano, Linda Galvani, Elena Parlagreco, Elisa Andrini, Davide Campana, Maria Pia Brizzi, Giuseppe Lamberti, Anna La Salvia
Neuroendocrine tumors (NETs) are rare neoplasms with a wide spectrum of clinical behavior, from the long survival of well-differentiated NETs to the dismal prognosis of high-grade neuroendocrine carcinomas (NECs), being G3 NETs a recently recognized intermediate entity. While the role of chemotherapy is well established in NECs, data on NETs mostly derives from small studies, experts' opinions, and extrapolating results from small-cell lung cancer studies. This narrative review aims to summarize available evidence about the use of chemotherapy in the setting of G1-2 NETs and G3 NETs...
January 16, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/36675644/resilience-stress-well-being-and-sleep-quality-in-multiple-sclerosis
#18
JOURNAL ARTICLE
Anne Marie Novak, Shahar Lev-Ari
(1) Background: Multiple Sclerosis (MS) is a chronic, progressive, immune-mediated disorder that affects the Central Nervous System and is the most common cause of non-traumatic neurological disability in young adults. The study aimed to assess the levels of stress, resilience, well-being, sleep quality, and fatigue in Israeli people with MS (PwMS), and to examine the associations between these factors and the sociodemographic and clinical characteristics. These factors had never before been studied in conjunction in PwMS, nor had they been systematically addressed in Israel, the unique geopolitical situation of which may pose unique challenges...
January 16, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/36675643/developing-a-deep-learning-model-to-evaluate-bulbar-conjunctival-injection-with-color-anterior-segment-photographs
#19
JOURNAL ARTICLE
Shanshan Wei, Yuexin Wang, Faqiang Shi, Siman Sun, Xuemin Li
The present research aims to evaluate the feasibility of a deep-learning model in identifying bulbar conjunctival injection grading. Methods: We collected 1401 color anterior segment photographs demonstrating the cornea and bulbar conjunctival. The ground truth was bulbar conjunctival injection scores labeled by human ophthalmologists. Two convolutional neural network-based models were constructed and trained. Accuracy, precision, recall, F1-score, Kappa, and the area under the curve (AUC) were calculated to evaluate the efficiency of the deep learning models...
January 16, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/36675642/t-cells-immunophenotyping-and-cd38-overexpression-as-hallmarks-of-the-severity-of-covid-19-and-predictors-of-patients-outcomes
#20
JOURNAL ARTICLE
Nesrin I Tarbiah, Nuha A Alkhattabi, Abdullah J Alsahafi, Hani S Aljahdali, Husam M Joharjy, Maryam H Al-Zahrani, Aliaa M Sabban, Rana A Alghamdi, Maha J Balgoon, Reham A Khalifa
BACKGROUND: By the end of 2019, the COVID-19 pandemic spread all around the world with a wide spectrum of clinical presentations ranging from mild to moderate to severe or critical cases. T cell subtype dysregulation is mostly involved in the immunopathogenic mechanism. The present study aimed to highlight the role of monitoring T cell subtypes and their activation (expression of CD38) in COVID-19 patients compared to healthy subjects and their role in predicting severity and patients' outcomes...
January 16, 2023: Journal of Clinical Medicine
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