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JOURNAL ARTICLE
Emily Harris
No abstract text is available yet for this article.
March 22, 2023: JAMA
#2
JOURNAL ARTICLE
Emily Harris
No abstract text is available yet for this article.
March 22, 2023: JAMA
#3
JOURNAL ARTICLE
Emily Harris
No abstract text is available yet for this article.
March 22, 2023: JAMA
#4
JOURNAL ARTICLE
Bridget M Kuehn
No abstract text is available yet for this article.
March 22, 2023: JAMA
#5
JOURNAL ARTICLE
Emily Harris
No abstract text is available yet for this article.
March 22, 2023: JAMA
#6
JOURNAL ARTICLE
Emily Harris
No abstract text is available yet for this article.
March 22, 2023: JAMA
#7
JOURNAL ARTICLE
Emily Harris
No abstract text is available yet for this article.
March 22, 2023: JAMA
#8
JOURNAL ARTICLE
Emily Harris
No abstract text is available yet for this article.
March 22, 2023: JAMA
#9
JOURNAL ARTICLE
Emily Harris
No abstract text is available yet for this article.
March 22, 2023: JAMA
#10
JOURNAL ARTICLE
Emily Harris
No abstract text is available yet for this article.
March 22, 2023: JAMA
#11
JOURNAL ARTICLE
Issa J Dahabreh, Dhruv S Kazi
No abstract text is available yet for this article.
March 21, 2023: JAMA
#12
JOURNAL ARTICLE
Ewan C Goligher, Patrick R Lawler, Thomas P Jensen, Victor Talisa, Lindsay R Berry, Elizabeth Lorenzi, Bryan J McVerry, Chung-Chou Ho Chang, Eric Leifer, Charlotte Bradbury, Jeffrey Berger, Beverly J Hunt, Lana A Castellucci, Lucy Z Kornblith, Anthony C Gordon, Colin McArthur, Steven Webb, Judith Hochman, Matthew D Neal, Ryan Zarychanski, Scott Berry, Derek C Angus
IMPORTANCE: Randomized clinical trials (RCTs) of therapeutic-dose heparin in patients hospitalized with COVID-19 produced conflicting results, possibly due to heterogeneity of treatment effect (HTE) across individuals. Better understanding of HTE could facilitate individualized clinical decision-making. OBJECTIVE: To evaluate HTE of therapeutic-dose heparin for patients hospitalized for COVID-19 and to compare approaches to assessing HTE. DESIGN, SETTING, AND PARTICIPANTS: Exploratory analysis of a multiplatform adaptive RCT of therapeutic-dose heparin vs usual care pharmacologic thromboprophylaxis in 3320 patients hospitalized for COVID-19 enrolled in North America, South America, Europe, Asia, and Australia between April 2020 and January 2021...
March 21, 2023: JAMA
#13
JOURNAL ARTICLE
Pierre Bouzat, Jonathan Charbit, Paer-Selim Abback, Delphine Huet-Garrigue, Nathalie Delhaye, Marc Leone, Guillaume Marcotte, Jean-Stéphane David, Albrice Levrat, Karim Asehnoune, Julien Pottecher, Jacques Duranteau, Elie Courvalin, Anais Adolle, Dimitri Sourd, Jean-Luc Bosson, Bruno Riou, Tobias Gauss, Jean-François Payen
IMPORTANCE: Optimal transfusion strategies in traumatic hemorrhage are unknown. Reports suggest a beneficial effect of 4-factor prothrombin complex concentrate (4F-PCC) on blood product consumption. OBJECTIVE: To investigate the efficacy and safety of 4F-PCC administration in patients at risk of massive transfusion. DESIGN, SETTING, AND PARTICIPANTS: Double-blind, randomized, placebo-controlled superiority trial in 12 French designated level I trauma centers from December 29, 2017, to August 31, 2021, involving consecutive patients with trauma at risk of massive transfusion...
March 21, 2023: JAMA
#14
JOURNAL ARTICLE
Victor J Dzau
No abstract text is available yet for this article.
March 20, 2023: JAMA
#15
JOURNAL ARTICLE
John P A Ioannidis, Angelo Maria Pezzullo, Stefania Boccia
No abstract text is available yet for this article.
March 20, 2023: JAMA
#16
JOURNAL ARTICLE
Melissa Suran
No abstract text is available yet for this article.
March 20, 2023: JAMA
#17
JOURNAL ARTICLE
Joelle Natalie Mouhanna, Judith Simms-Cendan, Sabrina Pastor-Carvajal
No abstract text is available yet for this article.
March 17, 2023: JAMA
#18
JOURNAL ARTICLE
Ahsan Alam, Emilie Cornec-Le Gall, Ronald D Perrone
No abstract text is available yet for this article.
March 17, 2023: JAMA
#19
JOURNAL ARTICLE
Tumaini R Coker, Tina L Cheng, Marci Ybarra
No abstract text is available yet for this article.
March 16, 2023: JAMA
#20
JOURNAL ARTICLE
Joseph D Stern
No abstract text is available yet for this article.
March 16, 2023: JAMA
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