We have located links that may give you full text access.
Journal Article
Review
Rate control vs. rhythm control in the management of atrial fibrillation in elderly persons.
American Journal of Geriatric Cardiology 2005 March
Antiarrhythmic medications used to maintain sinus rhythm have long been the treatment of choice in atrial fibrillation. The results of five prospective randomized trials comparing the efficacy and safety of rhythm-control to rate-control strategies are now available. Reflecting the epidemiology of atrial fibrillation in the real world, most subjects enrolled in these investigations were elderly persons at increased risk of stroke or death. All of these trials have had similar results; these studies have failed to demonstrate a clear advantage of one treatment strategy over the other. A prespecified subgroup analysis among 3091 elderly patients in the Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) study revealed that rhythm control was associated with a higher risk of death than rate control. This review examines developments leading to and the implications and limitations of these trials and discusses recently issued practice guidelines and the justification for ongoing efforts to develop nonpharmacologic approaches to rhythm management in atrial fibrillation.
Full text links
Related Resources
Trending Papers
Executive Summary: State-of-the-Art Review: Unintended Consequences: Risk of Opportunistic Infections Associated with Long-term Glucocorticoid Therapies in Adults.Clinical Infectious Diseases 2024 April 11
Autoimmune Hemolytic Anemias: Classifications, Pathophysiology, Diagnoses and Management.International Journal of Molecular Sciences 2024 April 13
Clinical practice guidelines on the management of status epilepticus in adults: A systematic review.Epilepsia 2024 April 13
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app