Zhiwei Chen, Tianquan Huang, Taiyu He, Guanhua Zha, Qian Zhu, Gaoli Zhang, Dejuan Xiang, Min Chen, Hu Li, Ning Ling, Yinghua Lan, Shi Xiaofeng, Dazhi Zhang, Pan Xu, Qingbo Pan, Rui Song, Junxiong Cao, Yingzhi Zhang, Hongyan Xiang, Yali Feng, Ziqiao Yang, Biqiong Zhang, Wei Shen, Dachuan Cai, Mingli Peng, Peng Hu, Hong Ren
Given the pandemic of severe acute respiratory syndrome coronavirus 2 Omicron variants, booster vaccination (BV) using inactivated virus vaccines (the third dose) has been implemented in China. However, the immune responses after BV, especially those against Omicron, in patients with chronic hepatitis B virus (HBV) infection (CHB) are unclear. In this prospective longitudinal study, 114 patients with CHB and 68 healthy controls (HCs) were recruited after receiving inactivated vaccination. The anti-receptor-binding domain (RBD) immunoglobulin G (IgG), neutralizing antibodies (NAbs), neutralization against Omicron (BA2...
March 22, 2023: Journal of Medical Virology