We have located links that may give you full text access.
Clinical Trial
Comparative Study
Journal Article
Transanal endoscopic microsurgical excision of irradiated and nonirradiated rectal cancer. A 5-year experience.
Surgical Laparoscopy & Endoscopy 1998 August
Transanal endoscopic microsurgery (TEM) allows minimally invasive full-thickness local excision of rectal tumors with perirectal fat dissection. Thirty-seven patients with extraperitoneal rectal carcinoma underwent full thickness TEM resection for T1 (10 patients), T2 (20 patients), and T3 (6 patients) lesions, with associated radiotherapy in the second and third group. One patient, staged as T2, underwent full-dose radiotherapy and TEM and the pathologist did not find cancer cells on the specimen (pT0). Morbidity included would dehiscence and stool incontinence in three and two patients, respectively, that resolved with medical therapy and rectovaginal fistula in one patient that required reoperation. No perioperative mortality was observed. Mean follow-up was 35 months (range 17-60 months), with two local recurrences (5.4%) that were successfully retreated. Cancer-related mortality due to systemic metastases was 8.1%. This is the first clinical study reporting on the application of TEM combined with radiotherapy for the treatment of T2 and T3 rectal cancer in selected patients. This approach is feasible, safe, and appears to be effective at the present duration of follow-up, with preservation of normal and sphincter function.
Full text links
Related Resources
Trending Papers
Interstitial Lung Disease: A Review.JAMA 2024 April 23
Review article: Recent advances in ascites and acute kidney injury management in cirrhosis.Alimentary Pharmacology & Therapeutics 2024 March 26
Executive Summary: State-of-the-Art Review: Unintended Consequences: Risk of Opportunistic Infections Associated with Long-term Glucocorticoid Therapies in Adults.Clinical Infectious Diseases 2024 April 11
Clinical practice guidelines on the management of status epilepticus in adults: A systematic review.Epilepsia 2024 April 13
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app