We have located links that may give you full text access.
Case Reports
Journal Article
Research Support, Non-U.S. Gov't
Acute myelofibrosis in children: report on two cases.
In our report, myelofibrosis in children is discussed and two cases of acutely developing myelofibrosis in association with acute megakaryoblastic leukaemia (M7) are presented. In the first case (girl, 34 months), it was acute myelofibrosis of hypocellular marrow. Diagnosis of M7 was confirmed by positive reaction of blasts from peripheral blood with CD42 and CD61 monoclonal antibodies. In the other child (girl, 5 years old), Ph1(+) chronic myeloid leukaemia diagnosed 22 months earlier transformed to M7. Similar to the first case, no marrow aspirate could be obtained and the diagnosis of M7 was made by the bone marrow histology that showed the presence of grossly fibrosed, hypercellular marrow with a large number of dysplastic, maturing megakaryocytes. Neither of the children had Down's syndrome. Although according to FAB classification both cases represent the same haematological entity, their clinical and histopathological presentations are very different.
Full text links
Related Resources
Trending Papers
Executive Summary: State-of-the-Art Review: Unintended Consequences: Risk of Opportunistic Infections Associated with Long-term Glucocorticoid Therapies in Adults.Clinical Infectious Diseases 2024 April 11
Clinical practice guidelines on the management of status epilepticus in adults: A systematic review.Epilepsia 2024 April 13
Autoimmune Hemolytic Anemias: Classifications, Pathophysiology, Diagnoses and Management.International Journal of Molecular Sciences 2024 April 13
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app