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Unraveling the brain's response to COVID-19: How SARS-CoV-2 afflicts dopaminergic neurons.
Cell Stem Cell 2024 Februrary 2
COVID-19 patients often display dysfunctions of the nervous system, indicating an effect of SARS-CoV-2 on neural cells. Yang et al. now show that human stem-cell-derived dopaminergic neurons are susceptible to SARS-CoV-2, triggering inflammation and senescence. The study further identifies three FDA-approved drugs capable of reversing these cellular phenotypes.
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