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Scaling up GMP-grade dopaminergic cells for Parkinson's disease.
Cell Stem Cell 2024 January 5
Stem cell therapy for Parkinson's disease requires demonstration of safety and efficacy of dopaminergic cells derived from a cell line, consideration of dose, and whether this is deliverable at scale. Park et al. demonstrate these requirements for a new hESC line and that their manufacturing methods allow for its scalability.
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