We have located links that may give you full text access.
Neonatal outcome after vitrified day 3 embryo transfers: a preliminary study.
Fertility and Sterility 2009 July
OBJECTIVE: To compare and evaluate the neonatal outcome in infants born after vitrified day 3 embryo transfers with that of fresh day 3 embryo transfers.
DESIGN: Retrospective analysis.
SETTING: Private assisted reproductive center.
PATIENT(S): Sixty-nine women, who delivered 89 babies.
INTERVENTION(S): Surplus day 3 cleavage stage embryos were vitrified using ethylene glycol-based solution by cryoloop carrier system and transferred after warming.
MAIN OUTCOME MEASURE(S): Post-thaw survival of embryos, implantation and pregnancy rates (PR), neonatal outcome, and congenital birth defects.
RESULT(S): A total of 907 vitrified day 3 embryos from 285 cycles were warmed and 817 survived (90.37%), which were used for embryo transfer. The pregnancy, implantation, miscarriage, and live birth rates achieved were 36.84%, 18.11%, 7.71%, and 24.21%, respectively. Of the 69 deliveries, singleton, twins, and triplets comprised of 72.46%, 26.08%, 1.44%, respectively, and 8 (11.59%) were preterm deliveries. The mean Apgar scores were 8.3, 9.2, 9.4 at 1, 5, and 10 minutes. The congenital birth defect rate was 1.18%. These results were comparable with pregnancies using fresh embryo transfers.
CONCLUSION(S): This preliminary study shows that vitrification is an efficient method of cryopreservation of human day 3 embryos with neonatal outcome comparable to fresh embryo transfers.
DESIGN: Retrospective analysis.
SETTING: Private assisted reproductive center.
PATIENT(S): Sixty-nine women, who delivered 89 babies.
INTERVENTION(S): Surplus day 3 cleavage stage embryos were vitrified using ethylene glycol-based solution by cryoloop carrier system and transferred after warming.
MAIN OUTCOME MEASURE(S): Post-thaw survival of embryos, implantation and pregnancy rates (PR), neonatal outcome, and congenital birth defects.
RESULT(S): A total of 907 vitrified day 3 embryos from 285 cycles were warmed and 817 survived (90.37%), which were used for embryo transfer. The pregnancy, implantation, miscarriage, and live birth rates achieved were 36.84%, 18.11%, 7.71%, and 24.21%, respectively. Of the 69 deliveries, singleton, twins, and triplets comprised of 72.46%, 26.08%, 1.44%, respectively, and 8 (11.59%) were preterm deliveries. The mean Apgar scores were 8.3, 9.2, 9.4 at 1, 5, and 10 minutes. The congenital birth defect rate was 1.18%. These results were comparable with pregnancies using fresh embryo transfers.
CONCLUSION(S): This preliminary study shows that vitrification is an efficient method of cryopreservation of human day 3 embryos with neonatal outcome comparable to fresh embryo transfers.
Full text links
Related Resources
Trending Papers
Systemic lupus erythematosus.Lancet 2024 April 18
Should renin-angiotensin system inhibitors be held prior to major surgery?British Journal of Anaesthesia 2024 May
Autoimmune Hemolytic Anemias: Classifications, Pathophysiology, Diagnoses and Management.International Journal of Molecular Sciences 2024 April 13
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app