journal
https://read.qxmd.com/read/33838109/ramadan-and-covid-19-vaccine-hesitancy-a-call-for-action
#1
LETTER
Sarah N Ali, Wasim Hanif, Kiran Patel, Kamlesh Khunti
No abstract text is available yet for this article.
April 7, 2021: Lancet
https://read.qxmd.com/read/33838108/amid-political-and-civil-unrest-in-myanmar-health-services-are-inaccessible
#2
LETTER
Myo Nyein Aung, Chengshi Shiu, Wei-Ti Chen
No abstract text is available yet for this article.
April 7, 2021: Lancet
https://read.qxmd.com/read/33836155/cardiology-and-big-data-a-call-for-papers
#3
Stuart Spencer, Rupa Sarkar
No abstract text is available yet for this article.
April 6, 2021: Lancet
https://read.qxmd.com/read/33836154/from-torture-to-ultraviolence-medical-and-legal-implications
#4
Gunisha Kaur
No abstract text is available yet for this article.
April 6, 2021: Lancet
https://read.qxmd.com/read/33812474/covid-19-vaccines-in-high-risk-ethnic-groups
#5
LETTER
Rashmi S D'Souza, Ingrid Wolfe
No abstract text is available yet for this article.
April 1, 2021: Lancet
https://read.qxmd.com/read/33812473/breast-cancer
#6
REVIEW
Sibylle Loibl, Philip Poortmans, Monica Morrow, Carsten Denkert, Giuseppe Curigliano
Breast cancer is still the most common cancer worldwide. But the way breast cancer is viewed has changed drastically since its molecular hallmarks were extensively characterised, now including immunohistochemical markers (eg, ER, PR, HER2 [ERBB2], and proliferation marker protein Ki-67 [MKI67]), genomic markers (eg, BRCA1, BRCA2, and PIK3CA), and immunomarkers (eg, tumour-infiltrating lymphocytes and PD-L1). New biomarker combinations are the basis for increasingly complex diagnostic algorithms. Neoadjuvant combination therapy, often including targeted agents, is a standard of care (especially in HER2-positive and triple-negative breast cancer), and the basis for de-escalation of surgery in the breast and axilla and for risk-adapted post-neoadjuvant strategies...
April 1, 2021: Lancet
https://read.qxmd.com/read/33812472/leveraging-data-and-new-digital-tools-to-prepare-for-the-next-pandemic
#7
LETTER
Sally C Davies, Hala Audi, Mitch Cuddihy
No abstract text is available yet for this article.
April 1, 2021: Lancet
https://read.qxmd.com/read/33798501/build-back-fairer-achieving-health-equity-in-the-eastern-mediterranean-region-of-who
#8
Michael Marmot, Ahmed Al-Mandhari, Abdul Ghaffar, Maha El-Adawy, Rana Hajjeh, Wasiq Khan, Jessica Allen
No abstract text is available yet for this article.
March 30, 2021: Lancet
https://read.qxmd.com/read/33798500/gout
#9
REVIEW
Nicola Dalbeth, Anna L Gosling, Angelo Gaffo, Abhishek Abhishek
Gout is a common and treatable disease caused by the deposition of monosodium urate crystals in articular and non-articular structures. Increased concentration of serum urate (hyperuricaemia) is the most important risk factor for the development of gout. Serum urate is regulated by urate transporters in the kidney and gut, particularly GLUT9 (SLC2A9), URAT1 (SLC22A12), and ABCG2. Activation of the NLRP3 inflammasome by monosodium urate crystals with release of IL-1β plays a major role in the initiation of the gout flare; aggregated neutrophil extracellular traps are important in the resolution phase...
March 30, 2021: Lancet
https://read.qxmd.com/read/33798499/efficacy-of-chadox1-ncov-19-azd1222-vaccine-against-sars-cov-2-variant-of-concern-202012-01-b-1-1-7-an-exploratory-analysis-of-a-randomised-controlled-trial
#10
Katherine R W Emary, Tanya Golubchik, Parvinder K Aley, Cristina V Ariani, Brian Angus, Sagida Bibi, Beth Blane, David Bonsall, Paola Cicconi, Sue Charlton, Elizabeth A Clutterbuck, Andrea M Collins, Tony Cox, Thomas C Darton, Christina Dold, Alexander D Douglas, Christopher J A Duncan, Katie J Ewer, Amy L Flaxman, Saul N Faust, Daniela M Ferreira, Shuo Feng, Adam Finn, Pedro M Folegatti, Michelle Fuskova, Eva Galiza, Anna L Goodman, Catherine M Green, Christopher A Green, Melanie Greenland, Bassam Hallis, Paul T Heath, Jodie Hay, Helen C Hill, Daniel Jenkin, Simon Kerridge, Rajeka Lazarus, Vincenzo Libri, Patrick J Lillie, Catherine Ludden, Natalie G Marchevsky, Angela M Minassian, Alastair C McGregor, Yama F Mujadidi, Daniel J Phillips, Emma Plested, Katrina M Pollock, Hannah Robinson, Andrew Smith, Rinn Song, Matthew D Snape, Rebecca K Sutherland, Emma C Thomson, Mark Toshner, David P J Turner, Johan Vekemans, Tonya L Villafana, Christopher J Williams, Adrian V S Hill, Teresa Lambe, Sarah C Gilbert, Merryn Voysey, Maheshi N Ramasamy, Andrew J Pollard
BACKGROUND: A new variant of SARS-CoV-2, B.1.1.7, emerged as the dominant cause of COVID-19 disease in the UK from November, 2020. We report a post-hoc analysis of the efficacy of the adenoviral vector vaccine, ChAdOx1 nCoV-19 (AZD1222), against this variant. METHODS: Volunteers (aged ≥18 years) who were enrolled in phase 2/3 vaccine efficacy studies in the UK, and who were randomly assigned (1:1) to receive ChAdOx1 nCoV-19 or a meningococcal conjugate control (MenACWY) vaccine, provided upper airway swabs on a weekly basis and also if they developed symptoms of COVID-19 disease (a cough, a fever of 37·8°C or higher, shortness of breath, anosmia, or ageusia)...
March 30, 2021: Lancet
https://read.qxmd.com/read/33798498/thromboembolism-and-the-oxford-astrazeneca-covid-19-vaccine-side-effect-or-coincidence
#11
LETTER
Søren Dinesen Østergaard, Morten Schmidt, Erzsébet Horváth-Puhó, Reimar Wernich Thomsen, Henrik Toft Sørensen
No abstract text is available yet for this article.
March 30, 2021: Lancet
https://read.qxmd.com/read/33798497/pandemic-moves-and-countermoves-vaccines-and-viral-variants
#12
Rogier W Sanders, Menno D de Jong
No abstract text is available yet for this article.
March 30, 2021: Lancet
https://read.qxmd.com/read/33773613/migraine-epidemiology-and-systems-of-care
#13
REVIEW
Messoud Ashina, Zaza Katsarava, Thien Phu Do, Dawn C Buse, Patricia Pozo-Rosich, Aynur Özge, Abouch V Krymchantowski, Elena R Lebedeva, Krishnamurthy Ravishankar, Shengyuan Yu, Simona Sacco, Sait Ashina, Samaira Younis, Timothy J Steiner, Richard B Lipton
Migraine is a neurovascular disorder that affects over 1 billion people worldwide. Its widespread prevalence, and associated disability, have a range of negative and substantial effects not only on those immediately affected but also on their families, colleagues, employers, and society. To reduce this global burden, concerted efforts are needed to implement and improve migraine care that is supported by informed health-care policies. In this Series paper, we summarise the data on migraine epidemiology, including estimates of its very considerable burden on the global economy...
March 25, 2021: Lancet
https://read.qxmd.com/read/33773612/migraine-integrated-approaches-to-clinical-management-and-emerging-treatments
#14
REVIEW
Messoud Ashina, Dawn C Buse, Håkan Ashina, Patricia Pozo-Rosich, Mario F P Peres, Mi Ji Lee, Gisela M Terwindt, Rashmi Halker Singh, Cristina Tassorelli, Thien Phu Do, Dimos D Mitsikostas, David W Dodick
Migraine is a highly disabling neurological disorder that directly affects more than 1 billion individuals worldwide. Available treatment options differ between countries and include acute, preventive, and non-pharmacological therapies. Because of major progress in the understanding of migraine pathogenesis, novel mechanism-based medications have emerged and expanded the armamentarium of treatments. We provide a comprehensive overview of the current standard of care that will enable informed clinical management...
March 25, 2021: Lancet
https://read.qxmd.com/read/33773611/covid-19-vaccines-for-the-european-region-an-unprecedented-challenge
#15
Hans Kluge, Martin McKee
No abstract text is available yet for this article.
March 25, 2021: Lancet
https://read.qxmd.com/read/33773610/migraine-disease-characterisation-biomarkers-and-precision-medicine
#16
REVIEW
Messoud Ashina, Gisela M Terwindt, Mohammad Al-Mahdi Al-Karagholi, Irene de Boer, Mi Ji Lee, Debbie L Hay, Laura H Schulte, Nouchine Hadjikhani, Alexandra J Sinclair, Håkan Ashina, Todd J Schwedt, Peter J Goadsby
Migraine is a disabling neurological disorder, diagnosis of which is based on clinical criteria. A shortcoming of these criteria is that they do not fully capture the heterogeneity of migraine, including the underlying genetic and neurobiological factors. This complexity has generated momentum for biomarker research to improve disease characterisation and identify novel drug targets. In this Series paper, we present the progress that has been made in the search for biomarkers of migraine within genetics, provocation modelling, biochemistry, and neuroimaging research...
March 25, 2021: Lancet
https://read.qxmd.com/read/33773609/new-covid-19-resurgence-in-the-who-eastern-mediterranean-region
#17
LETTER
Pierre Nabeth, Mahmoud Hassan, Keyrellous Adib, Abdinasir Abubakar, Richard Brennan
No abstract text is available yet for this article.
March 25, 2021: Lancet
https://read.qxmd.com/read/33773118/the-first-and-second-waves-of-the-covid-19-pandemic-in-africa-a-cross-sectional-study
#18
Stephanie J Salyer, Justin Maeda, Senga Sembuche, Yenew Kebede, Akhona Tshangela, Mohamed Moussif, Chikwe Ihekweazu, Natalie Mayet, Ebba Abate, Ahmed Ogwell Ouma, John Nkengasong
BACKGROUND: Although the first wave of the COVID-19 pandemic progressed more slowly in Africa than the rest of the world, by December, 2020, the second wave appeared to be much more aggressive with many more cases. To date, the pandemic situation in all 55 African Union (AU) Member States has not been comprehensively reviewed. We aimed to evaluate reported COVID-19 epidemiology data to better understand the pandemic's progression in Africa. METHODS: We did a cross-sectional analysis between Feb 14 and Dec 31, 2020, using COVID-19 epidemiological, testing, and mitigation strategy data reported by AU Member States to assess trends and identify the response and mitigation efforts at the country, regional, and continent levels...
March 24, 2021: Lancet
https://read.qxmd.com/read/33773117/human-rights-and-fair-access-to-covid-19-vaccines-the-international-aids-society-lancet-commission-on-health-and-human-rights
#19
(no author information available yet)
No abstract text is available yet for this article.
March 24, 2021: Lancet
https://read.qxmd.com/read/33773116/the-medical-right-to-repair-the-right-to-save-lives
#20
LETTER
Shuhan He, Debbie Lai, Jarone Lee
No abstract text is available yet for this article.
March 24, 2021: Lancet
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