journal
https://read.qxmd.com/read/36931290/clinical-aspects-of-snakebite-envenoming-and-its-treatment-in-low-resource-settings
#1
REVIEW
David A Warrell, David J Williams
There is increasing recognition of the public health importance of snakebite envenoming. Worldwide annual incidence is likely to be 5 million bites, with mortality exceeding 150 000 deaths, and the resulting physical and psychological morbidity leads to substantial social and economic repercussions. Prevention through community education by trained health workers is the most effective and economically viable strategy for reducing risk of bites and envenoming. Clinical challenges to effective treatment are most substantial in rural areas of low-resource settings, where snakebites are most common...
March 14, 2023: Lancet
https://read.qxmd.com/read/36931289/improving-health-outcomes-of-people-with-diabetes-target-setting-for-the-who-global-diabetes-compact
#2
REVIEW
Edward W Gregg, James Buckley, Mohammed K Ali, Justine Davies, David Flood, Roopa Mehta, Ben Griffiths, Lee-Ling Lim, Jennifer Manne-Goehler, Jonathan Pearson-Stuttard, Nikhil Tandon, Gojka Roglic, Slim Slama, Jonathan E Shaw
The Global Diabetes Compact is a WHO-driven initiative uniting stakeholders around goals of reducing diabetes risk and ensuring that people with diabetes have equitable access to comprehensive, affordable care and prevention. In this report we describe the development and scientific basis for key health metrics, coverage, and treatment targets accompanying the Compact. We considered metrics across four domains: factors at a structural, system, or policy level; processes of care; behaviours and biomarkers such as glycated haemoglobin (HbA1c ); and health events and outcomes; and three risk tiers (diagnosed diabetes, high risk, or whole population), and reviewed and prioritised them according to their health importance, modifiability, data availability, and global inequality...
March 14, 2023: Lancet
https://read.qxmd.com/read/36924780/stalled-progress-in-reducing-maternal-mortality-globally-what-next
#3
JOURNAL ARTICLE
Cheryl A Moyer, Emma R Lawrence, Titus K Beyuo, Methodius G Tuuli, Samuel A Oppong
No abstract text is available yet for this article.
March 13, 2023: Lancet
https://read.qxmd.com/read/36924779/uk-public-health-science-2023-a-call-for-abstracts
#4
JOURNAL ARTICLE
Michael Fleming, Charlotte Vrinten
No abstract text is available yet for this article.
March 13, 2023: Lancet
https://read.qxmd.com/read/36924778/fezolinetant-for-treatment-of-moderate-to-severe-vasomotor-symptoms-associated-with-menopause-skylight-1-a-phase-3-randomised-controlled-study
#5
JOURNAL ARTICLE
Samuel Lederman, Faith D Ottery, Antonio Cano, Nanette Santoro, Marla Shapiro, Petra Stute, Rebecca C Thurston, Marci English, Catherine Franklin, Misun Lee, Genevieve Neal-Perry
BACKGROUND: Neurokinin 3 receptor antagonists are potential non-hormonal therapies for the treatment of vasomotor symptoms in menopausal women as options are scarce for those who cannot or do not want to take hormone therapy. Fezolinetant is one of the first non-hormonal neurokinin 3 receptor antagonists in development for the treatment of vasomotor symptoms due to menopause. This study investigated the safety and efficacy of fezolinetant for the treatment of moderate-to-severe vasomotor symptoms associated with menopause...
March 13, 2023: Lancet
https://read.qxmd.com/read/36924777/neurokinin-3-receptor-antagonists-for-menopausal-vasomotor-symptoms
#6
JOURNAL ARTICLE
Julia K Prague
No abstract text is available yet for this article.
March 13, 2023: Lancet
https://read.qxmd.com/read/36924776/it-is-time-for-ambitious-transformational-change-to-the-epidemic-countermeasures-ecosystem
#7
JOURNAL ARTICLE
Els Torreele, Christine McNab, Olusoji Adeyi, Roxana Bonnell, Mandeep Dhaliwal, Fatima Hassan, Michel Kazatchkine, Hani Kim, Jerome Kim, Helena Legido-Quigley, Joanne Liu, Sania Nishtar, Kiat Ruxrungtham, Petro Terblanche, Eloise Todd, Marcos da Silva Freire, Germán Velásquez, Ellen Johnson Sirleaf, Helen Clark
No abstract text is available yet for this article.
March 13, 2023: Lancet
https://read.qxmd.com/read/36913960/can-we-reduce-malaria-in-pregnancy-and-improve-birth-outcomes
#8
JOURNAL ARTICLE
Abel Kakuru, Prasanna Jagannathan
No abstract text is available yet for this article.
March 10, 2023: Lancet
https://read.qxmd.com/read/36913959/effect-of-monthly-intermittent-preventive-treatment-with-dihydroartemisinin-piperaquine-with-and-without-azithromycin-versus-monthly-sulfadoxine-pyrimethamine-on-adverse-pregnancy-outcomes-in-africa-a-double-blind-randomised-partly-placebo-controlled-trial
#9
JOURNAL ARTICLE
Mwayiwawo Madanitsa, Hellen C Barsosio, Daniel T R Minja, George Mtove, Reginald A Kavishe, James Dodd, Queen Saidi, Eric D Onyango, Kephas Otieno, Duolao Wang, Ulla Ashorn, Jenny Hill, Crispin Mukerebe, Samwel Gesase, Omari A Msemo, Victor Mwapasa, Kamija S Phiri, Kenneth Maleta, Nigel Klein, Pascal Magnussen, John P A Lusingu, Simon Kariuki, Jacklin F Mosha, Michael Alifrangis, Helle Hansson, Christentze Schmiegelow, Julie R Gutman, R Matthew Chico, Feiko O Ter Kuile
BACKGROUND: Intermittent preventive treatment in pregnancy (IPTp) with dihydroartemisinin-piperaquine is more effective than IPTp with sulfadoxine-pyrimethamine at reducing malaria infection during pregnancy in areas with high-grade resistance to sulfadoxine-pyrimethamine by Plasmodium falciparum in east Africa. We aimed to assess whether IPTp with dihydroartemisinin-piperaquine, alone or combined with azithromycin, can reduce adverse pregnancy outcomes compared with IPTp with sulfadoxine-pyrimethamine...
March 10, 2023: Lancet
https://read.qxmd.com/read/36907193/past-time-for-a-pactt-for-humanity
#10
JOURNAL ARTICLE
Ayoade Alakija
No abstract text is available yet for this article.
March 9, 2023: Lancet
https://read.qxmd.com/read/36898396/early-childhood-lower-respiratory-tract-infection-and-premature-adult-death-from-respiratory-disease-in-great-britain-a-national-birth-cohort-study
#11
JOURNAL ARTICLE
James Peter Allinson, Nishi Chaturvedi, Andrew Wong, Imran Shah, Gavin Christopher Donaldson, Jadwiga Anna Wedzicha, Rebecca Hardy
BACKGROUND: Lower respiratory tract infections (LRTIs) in early childhood are known to influence lung development and lifelong lung health, but their link to premature adult death from respiratory disease is unclear. We aimed to estimate the association between early childhood LRTI and the risk and burden of premature adult mortality from respiratory disease. METHODS: This longitudinal observational cohort study used data collected prospectively by the Medical Research Council National Survey of Health and Development in a nationally representative cohort recruited at birth in March, 1946, in England, Scotland, and Wales...
March 7, 2023: Lancet
https://read.qxmd.com/read/36898395/from-flowers-to-menstrual-flow-trackers-the-corporatisation-of-women-s-equality-and-wellbeing
#12
JOURNAL ARTICLE
Sarah Hawkes, Sapna Kedia, Sally Odunga, Minakshi Dahal
No abstract text is available yet for this article.
March 7, 2023: Lancet
https://read.qxmd.com/read/36898394/early-childhood-lower-respiratory-tract-infection-a-key-determinant-of-premature-adult-respiratory-mortality
#13
JOURNAL ARTICLE
Heather J Zar, Andrew Bush
No abstract text is available yet for this article.
March 7, 2023: Lancet
https://read.qxmd.com/read/36893775/the-catastrophic-response-to-the-earthquake-in-syria-the-need-for-corrective-actions-and-accountability
#14
JOURNAL ARTICLE
Samer Jabbour, Aula Abbara, Abdulkarim Ekzayez, Fouad M Fouad, Mohamad Katoub, Rabie Nasser
No abstract text is available yet for this article.
March 6, 2023: Lancet
https://read.qxmd.com/read/36893777/inflammation-and-cholesterol-as-predictors-of-cardiovascular-events-among-patients-receiving-statin-therapy-a-collaborative-analysis-of-three-randomised-trials
#15
JOURNAL ARTICLE
Paul M Ridker, Deepak L Bhatt, Aruna D Pradhan, Robert J Glynn, Jean G MacFadyen, Steven E Nissen
BACKGROUND: Inflammation and hyperlipidaemia jointly contribute to atherothrombotic disease. However, when people are treated with intensive statin therapy, the relative contributions of inflammation and hyperlipidaemia to the risk of future cardiovascular events might change, which has implications for the choice of adjunctive cardiovascular therapeutics. We aimed to evaluate the relative importance of high-sensitivity C-reactive protein (CRP) and low-density lipoprotein cholesterol (LDLC) as determinants of risk for major adverse cardiovascular events, cardiovascular death, and all-cause-death among patients receiving statins...
March 3, 2023: Lancet
https://read.qxmd.com/read/36893776/inflammation-contributes-to-cardiovascular-risk-in-patients-receiving-statin-therapy
#16
JOURNAL ARTICLE
Jean-Claude Tardif, Michelle Samuel
No abstract text is available yet for this article.
March 3, 2023: Lancet
https://read.qxmd.com/read/36889334/effect-of-a-nationwide-intervention-of-electronic-letters-with-behavioural-nudges-on-influenza-vaccination-in-older-adults-in-denmark
#17
JOURNAL ARTICLE
Melissa Stockwell
No abstract text is available yet for this article.
March 3, 2023: Lancet
https://read.qxmd.com/read/36889333/immediate-versus-staged-complete-revascularisation-in-patients-presenting-with-acute-coronary-syndrome-and-multivessel-coronary-disease-biovasc-a-prospective-open-label-non-inferiority-randomised-trial
#18
JOURNAL ARTICLE
Roberto Diletti, Wijnand K den Dekker, Johan Bennett, Carl E Schotborgh, Rene van der Schaaf, Manel Sabaté, Raúl Moreno, Koen Ameloot, Rutger van Bommel, Daniele Forlani, Bert van Reet, Giovanni Esposito, Maurits T Dirksen, Willem P T Ruifrok, Bert R C Everaert, Carlos Van Mieghem, Jacob J Elscot, Paul Cummins, Mattie Lenzen, Salvatore Brugaletta, Eric Boersma, Nicolas M Van Mieghem
BACKGROUND: In patients with acute coronary syndrome and multivessel coronary disease, complete revascularisation by percutaneous coronary intervention (PCI) is associated with improved clinical outcomes. We aimed to investigate whether PCI for non-culprit lesions should be attempted during the index procedure or staged. METHODS: This prospective, open-label, non-inferiority, randomised trial was done at 29 hospitals across Belgium, Italy, the Netherlands, and Spain...
March 3, 2023: Lancet
https://read.qxmd.com/read/36889332/electronic-nudges-to-increase-influenza-vaccination-uptake-in-denmark-a-nationwide-pragmatic-registry-based-randomised-implementation-trial
#19
JOURNAL ARTICLE
Niklas Dyrby Johansen, Muthiah Vaduganathan, Ankeet S Bhatt, Simin Gharib Lee, Daniel Modin, Brian L Claggett, Erica L Dueger, Sandrine I Samson, Matthew M Loiacono, Lars Køber, Scott D Solomon, Pradeesh Sivapalan, Jens Ulrik Stæhr Jensen, Cyril Jean-Marie Martel, Palle Valentiner-Branth, Tyra Grove Krause, Tor Biering-Sørensen
BACKGROUND: Influenza vaccination rates remain suboptimal despite effectiveness in preventing influenza infection and related complications. We investigated whether behavioural nudges, delivered via a governmental electronic letter system, would increase influenza vaccination uptake among older adults in Denmark. METHODS: We did a nationwide, pragmatic, registry-based, cluster-randomised implementation trial during the 2022-23 influenza season in Denmark. All Danish citizens aged 65 years or older or turning 65 years by Jan 15, 2023 were included...
March 3, 2023: Lancet
https://read.qxmd.com/read/36889331/revascularisation-in-acute-coronary-syndromes-change-in-practice
#20
JOURNAL ARTICLE
Tobias F S Pustjens, Pieter A Vriesendorp, Arnoud W J Van't Hof
No abstract text is available yet for this article.
March 3, 2023: Lancet
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