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Following the Dropouts - Interpreting an 11-Year Follow-up Study.
NEJM Evid 2023 August
In this edition of NEJM Evidence , Lohmander et al.1 report on the 11-year follow-up for a randomized clinical trial (KANON [Knee Anterior Cruciate Ligament Nonsurgical vs. Surgical Treatment]) of early anterior cruciate ligament reconstruction (ACLR) versus optional delayed ACLR in young, active adults. This is the third publication reporting on this trial, which enrolled 121 participants from February 2002 through June 2006. A 2010 article2 reported on the 2-year follow-up, and a 2013 article3 reported on the 5-year follow-up. Both of these analyses concluded that early ACLR did not lead to improved patient-reported outcomes relative to optional delayed ACLR.
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