Hassan M Sakr, Mahmoud R AbdulSalam, Mostafa I Fayad, Rania Moussa, Abdullah Ali H Alzahrani
Introduction Since the polished and fitting surface of the denture base may promote the colonization of microorganisms, it is essential to know how the different types of denture bases prevent or encourage the adhesion of microorganisms. This study aimed to compare the microbial adhesion to the polished and fitting surfaces of thermoplastic nylon, thermoplastic acetal, and thermoplastic acrylic denture bases in Kennedy Class Ⅰ, partially edentulous patients. Materials and methods Thirteen patients were included in the study...
May 2024: Curēus
Buț Mădălina-Georgiana, Silvia Imre, Camil Vari, Bianca Eugenia Ősz, Ruxandra Ștefănescu, Amalia Pușcaș, George Jîtcă, Camelia-Maria Matei, Amelia Tero-Vescan
Introduction Benign prostatic hyperplasia (BPH) is a prevalent condition among aging men that affects their life quality due to urinary symptoms. Current pharmacologic treatments, often lead to sexual dysfunction, so dietary supplements (DS) containing plant-based compounds such as β-sitosterol (SIT) are preferred. DS are highly accessible and widely used, but poorly regulated, so often patients are victims of fraud. The use of DS to treat BPH symptoms is questionable, and this may be due not to the efficacity of the active compound but to the quality of commonly available DS...
May 2024: Curēus
Nikita Singh, Pawel Borkowski, Shaunak Mangeshkar, Vibhor Garg, Bisrat H Adal
Acute coronary syndrome (ACS) presents significant diagnostic challenges, particularly in cases with atypical presentations and complex clinical scenarios. Here, we describe the case of a 59-year-old man who presented with presyncope, bradycardia, hypotension, and later syncope, attributed to the Bezold-Jarisch reflex. Electrocardiographic findings suggested both inferior and anterior wall infarction, with dynamic changes in T-wave morphology further complicating the diagnostic process. Despite a type A Wellens' pattern indicating critical stenosis in the proximal left anterior descending (LAD) artery, coronary angiography revealed a complete thrombotic lesion in the proximal right coronary artery (RCA), necessitating urgent intervention...
May 2024: Curēus
Larisa Cristina Tomescu, Ioan Sas, Simona Sarb, Anca Maria Cimpean
Background Human embryo vasculogenesis (blood vessel development starting from endothelial precursors) includes the ability of mesenchymal cells and pluripotent stem cells to differentiate into endothelial cells. Quantification of endothelial progenitor cells is difficult to assess during the early steps of human embryo development due to several factors, especially due to the paucity of human embryo tissue which is usually discarded after early-stage pregnancy abortive methods. CD133 (Promimin-1) is a general marker of progenitor cells, but combined with other endothelial markers such as CD34, it may identify endothelial progenitor cells during embryonic development...
May 2024: Curēus
Ranim F Al Derbas, Sarah A Al Nafisi, Ahmad T Al Khiary, Fatimah S Al Ghamdi, Fadel Z Al Oatibi
Castleman disease (CD) is a rare lymphoproliferative disorder characterized by abnormal lymph node enlargement. We present the first documented case of a stroma-rich variant of hyaline vascular Castleman disease in Saudi Arabia. A 24-year-old Saudi female known to have acetylcholine receptor antibody-positive myasthenia gravis (MG) presented with shortness of breath, oral thrush, and an acute myasthenia gravis exacerbation, necessitating intensive care unit (ICU) admission. During her hospitalization, she was found to have a large pelvic mass...
May 2024: Curēus
Ngoc Hung Pham, Khac Sang Phan, Cong Le Kha Bui, Van Quoc Anh Nguyen, Luong Vinh Le, Thanh Liem Ngo, Kim Tuan Nguyen, Van Can Truong, Ngoc Khanh Tran
BACKGROUND: There are several types of benign renal diseases, such as urological stones, ureteropelvic junction obstruction, renal vascular disease, and inflammation, which are responsible for nonfunctioning kidneys. Laparoscopic nephrectomy (LN) is the gold standard for treating nonfunctioning kidneys with complications. This study presents the results of our initial experiences with 3D laparoscopic nephrectomy (3D-LN) for benign, nonfunctioning kidneys. METHODS: From July 2021 to July 2023, 40 consecutive patients who underwent 3D transperitoneal laparoscopic nephrectomy were retrospectively evaluated at the Department of Urology and Department of General Surgery, Hue Central Hospital, Hue, Vietnam...
May 2024: Curēus
Andrada Cosoreanu, Emilia Rusu, Doina Andrada Mihai, Florin Rusu, Ileana Pantea, Ioana Paunica, Ioana Ungureanu, Gabriela Radulian
Background Distress in patients with diabetes is a condition that has received significant attention in recent years; however, data regarding the psychological assessment and the impact of the emotional burden of diabetes among the Roma population are still scarce in the medical literature. Material and methods We conducted an observational, transversal study that included 310 adult patients with diabetes mellitus, aged between 18 and 85 years old, of which the majority (61%) were women; patients were selected from a tertiary hospital providing diabetes care; diabetes distress was evaluated using a standardized questionnaire, the diabetes distress scale (DDS), validated on Romanian patients...
May 2024: Curēus
Majed Almalki, Waad F Khayat
INTRODUCTION: Informed consent is a legal process intended to protect patients' rights and ensure ethical medical practice. The aim of this cross-sectional study was to assess dentists' practice of obtaining informed consent and adherence to the recommended guidelines, and to investigate the types of consent, barriers, the process, and the quality of the information included in preoperative informed consent for endodontic treatment in Saudi Arabia. METHODS: A validated self-administered online questionnaire was developed and distributed to dentists performing endodontic treatment in Saudi Arabia...
May 2024: Curēus
Chitra R, Yuvaraj Karthick, Kamalraj Sundaramoorthy, Anupama Mohankumar
Benign breast diseases are a common presentation in the breast clinic outpatient department. These diseases, including giant fibroadenoma, multiple fibroadenoma in different quadrants, and large or recurrent phyllodes tumors, pose challenges in surgical management. We present a case series of 16 patients aged 19 to 63 years (average age, 41.5 years) who presented with breast lumps and underwent surgery using the round block technique for benign breast diseases at our institute between November 2019 and March 2024...
May 2024: Curēus
ِAbdel Naser M Emam
OBJECTIVES: Accurate occlusal vertical dimension (OVD) establishment is an essential component of prosthodontic treatment. No accurate approach exists to determine the appropriate OVD for patients without posterior teeth. This study aimed to correlate the accuracy of the nose-to-chin distance with various facial measurements and thumb length in dentulous and edentulous Saudi patients. MATERIALS AND METHODS: The participants comprised 100 fully dentulous Saudi male dental students aged 20-30 years (group 1) and 20 completely edentulous patients aged 60-70 years (group 2)...
May 2024: Curēus
George Mpourazanis, Haralambos V Harissis, Konstantinos Seretis, Petros Papalexis, Ioannis Korkontzelos, Romanos Vogiatzis, Ioannis Kosmas, Anastasia Zagaliki, Panagiotis Tsirkas
Borderline phyllodes tumor is a rare and benign form of breast cancer with malignant potential. According to the World Health Organization (WHO), phyllodes tumor is classified into three categories: benign, borderline, and malignant. The treatment of phyllodes tumor is wide focal excision combined with radiotherapy and chemotherapy in certain cases. Herein, we report a 47-year-old female who presented with a giant borderline mass approximately 19.5 x 16.9 x 9.3 cm in size. From medical history, we noticed that the mass begun to develop during puberty...
May 2024: Curēus
Yojiro Ishikawa, Satoshi Teramura, Hiroshi Nakano, Kengo Ito, Takayuki Yamada
Background Studies investigating the normative characteristics and prognosis of patients diagnosed with brain metastases (BMs) at the onset of cancer are scarce. Therefore, we analyzed real-world treatment options. Methodology This retrospective study enrolled 112 patients newly diagnosed with BM between May 2006 and October 2021. The variables examined included patients' age, sex, recurrence split analysis, Glasgow prognostic score (GPS), number of lesions, tumor size, peripheral brain tumor edema, targeted therapy, supportive care, chemotherapy, and date of onset...
May 2024: Curēus
Rowena John, Nur Afiqah Mohd Salleh, Nik Daliana Nik Farid
Background The sexual well-being of youths is crucial as it establishes the foundation for their sexual health throughout their lives. Malaysia's Ministry of Health (MOH) mainly delivers sexual reproductive health (SRH) services. Besides MOH, the National Population Family Development Board (NPFDB), under the purview of the Ministry of Women, Family and Community Development and Federation of Reproductive Health Association Malaysia, works closely with MOH to ensure the delivery of SRH information and services...
May 2024: Curēus
Shai Ring, Alexander Llop, Harris Khawaja, Usman Khan, Muhammad Usman Khan
We present the case of an elderly female who presented to the emergency department with dizziness. She was found to have an acute chronic kidney injury complicated by a complete heart block (CHB). She received a transvenous pacemaker and was taken for hemodialysis (HD) with complete resolution of her heart block. The following day, she was noted to be symptomatic and bradycardic. A repeat electrocardiogram showed a recurrence of the CHB. She was taken again for HD which led to the resolution of her conduction abnormalities...
May 2024: Curēus
Silvia Pérez-Trigo, Regina-María López-Ladrón-García-Borbolla, Enrique Mencía-Gutiérrez, María Garrido-Ruíz, Álvaro Bengoa-González
Eccrine poroma is a rare benign adnexal tumor arising from intradermal cells of eccrine sweat ducts. At least two-thirds of eccrine poromas present on the extremities, most commonly on the palms and soles. They are scarcely found on the face; to date, only 11 cases of eyelid poromas have been reported in PubMed. Biopsy excision with a free margin is necessary to distinguish it from malignant lesions and avoid recurrence with possible transformation to porocarcinoma. We present the case of a 23-year-old male with a histopathological confirmation of poroma using staining with hematoxylin-eosin on the eyelid, previously clinically diagnosed with molluscum contagiosum...
May 2024: Curēus
Sindhu Harika Peketi, Pratap Kumar Upadrista, Bair Cadet, Johanne Cadet, Noonkee Cadet
Salicylate exposure and toxicity are associated with a myriad of symptoms and signs, and a comprehensive knowledge of diagnosing and treating salicylate poisoning is needed. Here, we present a case of a 29-year-old female with a past medical history of schizoaffective disorder and bipolar disorder with multiple suicide attempts brought to our hospital, Nassau University Medical Center, East Meadow, by the Emergency Medical Service (EMS) due to an intentional overdose of 300 pills of acetylsalicylic acid...
May 2024: Curēus
Ning Zhang, Changyi Liu, Lin Kang, Jianfeng Zhou, Wenjing Liu, Xuan Qu
Actinomycosis is a chronic granulomatous disease that can affect various parts of the body, including the head and neck, lungs, abdominal and pelvic cavities, and wounds. It is caused by different actinomycetes like Actinomyces sherdii , Actinomyces glasii , Actinomyces cariosa , Actinomyces zurichensis , and Actinomyces europaea . Reported infections caused by actinomycetes include pulmonary actinomycosis, pelvic and abdominal infections, bone or artificial joint infections, endocarditis, complicated urinary tract infections, and soft tissue abscesses...
May 2024: Curēus
Achilleas Betsikos, Eleni Paschou, Virginia Geladari, Stauroula Magaliou, Nikolaos Sabanis
Abiraterone, an inhibitor of both 17α-hydroxylase and 17,20-lyase, is considered a novel, state-of-the-art, life-prolonging therapy in the urologists' arsenal when treating prostate cancer. Despite its efficacy, it is linked with an increased risk of cardiovascular adverse effects. Herein, we report a case in which the administration of abiraterone resulted in a full-blown syndrome of apparent mineralocorticoid excess despite the concomitant administration of prednisolone; that is, secondary hypertension, hypokalemia, metabolic alkalosis, as well as elevated levels of adrenocorticotropic hormone (ACTH)...
May 2024: Curēus
Sai Rakshith Gaddameedi, Mahrukh A Khan, Fnu Arty, Vandana Bandari, Anoohya Vangala, Pratik Panchal, Shazia M Shah
Symptomatic cerebral infarcts with cryptogenic ischemic stroke pose diagnostic challenges due to unknown etiology. Notably, up to half of young individuals with cryptogenic stroke exhibit patent foramen ovale (PFO), while finasteride, which is used for male pattern baldness, elevates testosterone levels, potentially increasing the risk of thrombosis. Here, we present a case of thalamic infarction in a 21-year-old male devoid of cerebrovascular risk factors but with PFO and finasteride use. The patient presented with short-term memory issues, otherwise lacking medical history or substance use...
May 2024: Curēus
Cosmin Nișcoveanu, Deria Refi, Bogdan Obada, Serban Dragosloveanu, Cristian Scheau, Radu Octavian Baz
Vertebral limbus is a condition characterized by the intraspongious herniation of a portion of the nucleus pulposus. It is often asymptomatic, but it can sometimes cause nonspecific symptoms such as local pain and muscle spasm, or, in rare cases, radiculopathies, which is why it can be confused with vertebral fractures, spondyloarthropathies, infectious or tumoral processes. Early recognition of this pathology is preferable for a correct diagnosis and adequate treatment, the latter ranging from conservative approaches (such as personalized exercise programs and physical therapy) to surgical interventions reserved for severe cases with nerve compression...
May 2024: Curēus
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