Rashad I Shaadouh, Mohammad Y Hajeer, Rabab Al-Sabbagh, Mohammad Khursheed Alam, Ghiath Mahmoud, Ghassan Idris
BACKGROUND: Shortening the duration of orthodontic treatment by speeding up the rate of tooth movement has become an essential goal for both orthodontists and patients. This preliminary report aimed to investigate the safety and effectiveness of a new intraoral removable electrical device in accelerating the en-masse retraction of the upper anterior teeth using low-intensity direct electrical current. METHODS: This prospective preliminary interventional clinical study was conducted at the Department of Orthodontics, Faculty of Dentistry, Damascus University, Syria, between March 2019 and February 2020...
May 2023: Curēus
Guy Hayakawa, Maya M Leibowitz, Sudipta Datta, Samson O Oyibo
Treatment with immune checkpoint inhibitors has improved the prognosis of solid tumors. However, immune-related adverse events (IRAEs), including exacerbation of pre-existing autoimmune disease, are common and have become more frequent with combination therapy. The literature is scanty regarding reports of the use of combination immune checkpoint therapy in patients with pre-existing autoimmune hypothyroidism. We report a case of a man with a history of hypothyroidism, who developed transient thyroiditis, characterized by a thyrotoxic phase followed by a severe hypothyroid phase soon after receiving combination therapy (nivolumab and ipilimumab) for the treatment of a malignant pleural mesothelioma...
May 2023: Curēus
Pavan Kumar Reddy Kalluru, Mahesh Mamilla, Sai Sudha Valisekka, Saikiran Mandyam, Ernesto Calderon Martinez, Sarojini Posani, Shriya Sharma, Ravikishore Reddy Gopavaram, Borgharkar Gargi, Anvitha Gaddam, Sushritha Reddy
A systematic review was conducted to investigate the relationship between aminotransferases and the severity of dengue infection, which is a prevalent and significant infection in tropical and subtropical regions. Aminotransferases are enzymes that are often elevated in dengue due to the liver's physiological and immunological response to the infection. This review focused on analyzing various studies that examined the correlation between aminotransferase levels and the severity of dengue. Extensive literature searches were performed using ("dengue*" OR "dengue fever*" OR "dengue haemorrhagic fever*" OR "dengue shock syndrome*") AND ("alanine aminotransferase*" OR "aspartate aminotransferase*") on PubMed...
May 2023: Curēus
Muhammad Ahmad, Laura Warren, Hnin Ingyin, Anam Naumaan, Annacarolina F Da Silva
Angiosarcoma is a malignant neoplasm showing morphological or immunophenotypic evidence of endothelial differentiation with either a vascular or lymphatic origin. It has a strong predilection for skin and deep soft tissue. Angiosarcomas of the gynecologic tract are very uncommon, and very few cases have been described in medical literature up to this day. Primary vaginal angiosarcomas with no prior history of radiation are exceedingly rare. The epithelioid subtype of primary vaginal angiosarcomas is even more uncommon...
May 2023: Curēus
Joseph M Hendrix
Pulmonary hypertension (PH) is characterized by narrowing small pulmonary arteries, escalating pulmonary vascular resistance, and affecting the entire cardiovascular system. Pulmonary arterial hypertension (PAH) represents a subgroup of PH and typically affects one in 20,000 individuals. When treating individuals with PAH for non-cardiothoracic surgery, anesthetic management strategies should be tailored to the individual's specific needs. This literature review assessed the anesthetic management of PAH in non-cardiothoracic surgery...
May 2023: Curēus
Abdulsalam Aleid, Basmah S Alzahrani, Murtadha H Alameer, Abdulsalam J Alhassan, Ibrahim Alahmed
Epidural hematomas (EDHs) are a neurosurgical emergency characterized by the accumulation of blood in the epidural space surrounding the dura mater. Spontaneous resolution of EDH is an exceptionally rare occurrence, with only 16 cases reported in the medical literature where resolution occurred within 24 hours of onset. In this case report, we present a unique instance of a chronic EDH that spontaneously resolved over a period of seven months. This case adds to the scientific literature by highlighting an extremely prolonged duration of spontaneous EDH resolution, which, to our knowledge, has not been previously documented...
May 2023: Curēus
Sergiu Iordache, Mihai Costache, Adrian Cursaru, Bogdan Serban, Razvan Spiridonica, Mihnea Popa, Catalin Cirstoiu, Bogdan Cretu
The number of individuals who experience the symptoms of gonarthrosis rises proportionally as life expectancy rises and the population becomes more active. The purpose of total knee arthroplasty (TKA) is to lessen pain and restore knee function, and it has a high success rate. The restoration of patellar tracking in addition to the proper alignment of the femoral and tibial components contributes to the success of the arthroplasty and the patient's happiness. Replacement of the knee is not an easy process. One of the major objectives of total knee replacement is to achieve the proper rotation of the femoral components...
May 2023: Curēus
Haitam Almoffarreh, Nouf Alkaabi, Abdullatif Alkhurayji
Thyroid abscess is a rare encounter due to its unique histological and structural features. It is usually associated with some form of congenital anomalies in pediatrics especially if recurred. Early recognition and treatment are of paramount importance in preventing complications. Atypical presentation can occur if the patient is improperly treated prior to presentation. Conservative management is becoming the mainstay of treatment unless there is a risk of airway compromise or extension. We report the case of a 15-month-old female who presented with anterior neck swelling...
May 2023: Curēus
Alexander M DeLeon, Joseph Rivera-Monfeli, Talal A Akbar, Bruno DeCaria
Vasovagal syncope has been associated with chronic pain procedures, phlebotomy, and musculoskeletal injections. While vasovagal syncope is commonly associated with interventional pain procedures, its occurrence during peripheral nerve block procedures has not been reported. We report a case of vasovagal syncope leading to transient asystole in a patient undergoing a lower extremity peripheral nerve block procedure. The episode resolved after halting the procedure and administering ephedrine, atropine, and intravenous fluids...
May 2023: Curēus
Zohour AlSomali, Eman Bajamal, Ola Esheaba
INTRODUCTION: Antenatal (prenatal) education is a vital role of midwives when giving antenatal care to pregnant women. Particularly in the late stages of pregnancy, antenatal education regarding the natural-labor process, the introduction of labor rooms, coping strategies, and labor-pain management may enhance maternal self-efficacy and perceptions of childbirth. However, educational programs that include birth plans, pain-relief measures, and birth preparation are not a structured part of the Saudi healthcare system...
May 2023: Curēus
Mohamad-Hani Temsah, Amr Jamal, Fadi Aljamaan, Jaffar A Al-Tawfiq, Ayman Al-Eyadhy
The fusion of insights from the comprehensive global burden of disease (GBD) study and the advanced artificial intelligence of open artificial intelligence (AI) chat generative pre-trained transformer version 4 (ChatGPT-4) brings the potential to transform personalized healthcare planning. By integrating the data-driven findings of the GBD study with the powerful conversational capabilities of ChatGPT-4, healthcare professionals can devise customized healthcare plans that are adapted to patients' lifestyles and preferences...
May 2023: Curēus
Surag Kr, Anshuman Singh, Pritam Sharma, Vivek Pai, Anupam Choudhary, Shreenath Patil
Introduction This study focuses on investigating the effect of routine nephrostomy tube placement in patients with moderate renal calculi of size 2.5 cm or less who undergo uncomplicated percutaneous nephrolithotomy (PCNL) procedures. Previous studies have not specified whether only uncomplicated cases were included in the analysis, which may affect the results. This study aims to provide a clearer understanding of the effect of routine nephrostomy tube placement on blood loss in a more homogeneous patient population...
May 2023: Curēus
Hiroki Kawamata, Taku Hatta, Atsushi Takahashi, Satoshi Tateda, Mika Abe
A medial condyle fracture of the humerus with preexisting fishtail deformity and lateral condyle nonunion is very rare, and there have been few reports describing favorable treatment options. We herein report the case of an 83-year-old woman who sustained a medial condyle fracture of her elbow with a comorbidity of long-lasting limited elbow motion with a history of elbow trauma in childhood. After conservative treatment with casting for four weeks, unstable medial condyle fracture in the presence of fishtail deformity and lateral condyle nonunion remained...
May 2023: Curēus
Andrea Messori, Sabrina Trippoli, Valeria Fadda, Maria Rita Romeo
In medical devices, recent studies have proposed original approaches for standardizing competitive tenders with the aim of promoting reproducibility, avoiding discretional decisions, and applying value-based principles. In the framework of tenders' standardization, the net monetary benefit (NMB) method has attracted much interest, but its mathematical complexity has prevented a wide application. In the present work, we developed a procurement model that simplifies clinical information management for high-technology devices purchased for our public hospitals...
May 2023: Curēus
Alana Sadur, Theodore Quan, Chelsea Nguyen, Sean Tabaie
Purpose Metabolic syndrome is associated with postoperative morbidity and mortality in surgical patients. With the increased use of arthroscopic techniques for rotator cuff repair (RCR), it is important to identify the impact this disorder has on surgical patients. The purpose of this study is to evaluate the clinical impact of metabolic syndrome on outcomes following arthroscopic RCR. Methods The 2006-2019 National Surgical Quality Improvement Program database was queried for adult patients who underwent arthroscopic RCR...
May 2023: Curēus
Abdulaziz F Alkheraiji, Ismail Almogbil, Moath Aljohani, Abdulmalik B Albaker, Hussain Algawahmed
[This corrects the article DOI: 10.7759/cureus.37554.].
May 2023: Curēus
Abhinav Grover, Mansi Oberoi, Harmeet Singh Rehan, Lalit K Gupta, Madhur Yadav
[This corrects the article DOI: 10.7759/cureus.6542.].
May 2023: Curēus
Elvina Almuradova, Suayib Yalcin, Rukiye Arıkan, Murat Ayhan, Hacer Demir, Gokcen Tugba Cevik, Mustafa Karaca, Ibrahim Petekkaya, Bulent Karabulut
BACKGROUND: The management of early rectal cancer is different from that of colon cancer in terms of radiotherapy (RT) requirements or neoadjuvant treatment. It is not clear how the course of rectal cancer differs from that of the colon in a metastatic setting or how it should be approached differently. This study aimed to evaluate outcomes after combining downsizing chemotherapy (CTx) with rescue surgery. METHODS: Eighty-nine patients (57 men and 32 women) diagnosed with metastatic rectal cancer with resectable disease after systemic CTx were included in the study...
May 2023: Curēus
Vishal V Bhende, Tanishq S Sharma, Krishnan Ganapathy Subramaniam, Deepakkumar V Mehta, Jigar P Thacker, Ashwin S Sharma, Amit Kumar, Gurpreet Panesar, Kunal A Soni, Kartik B Dhami, Nirja Patel, Hardil P Majmudar, Sohilkhan R Pathan
One-stage total correction is known to be anatomically unsuitable for correcting tetralogy of fallot (TOF) in a certain proportion of children. Surgeons are thus faced with dilemmas regarding which preliminary operation for the anomaly to do first. Brock's primary postulation suggests that pulmonary trunk and annulus enlargement leading to the correction of the outflow obstruction will favor the subsequent total correction. In line with this, the current article presents two patients who were 6 months and 5 years old...
May 2023: Curēus
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