Renata Moll-Bernardes, Juliana R Ferreira, Andréa Silvestre Sousa, Mariana B Tortelly, Adriana L Pimentel, Ana Cristina B S Figueiredo, Eduardo B Schaustz, José Carlos Pizzolante Secco, Allan Robson Kluser Sales, Flavia V O Terzi, Adriana Xavier de Brito, Renée O Sarmento, Marcia M Noya-Rabelo, Sergio Fortier, Flavia A Matos E Silva, Narendra Vera, Luciana Conde, Mauro Jorge Cabral-Castro, Denilson C Albuquerque, Paulo Rosado de-Castro, Gabriel C Camargo, Martha V T Pinheiro, Olga F Souza, Fernando A Bozza, Ronir R Luiz, Emiliano Medei
BACKGROUND: Comorbidities such as obesity, hypertension, and diabetes are associated with COVID-19 development and severity, probably due to immune dysregulation; however, the mechanisms underlying these associations are not clear. The immune signatures of hypertensive patients with obesity with COVID-19 may provide new insight into the mechanisms of immune dysregulation and progression to severe disease in these patients. METHODS: Hypertensive patients were selected prospectively from a multicenter registry of adults hospitalized with COVID-19 and stratified according to obesity (BMI ≥ 30 kg/m²)...
November 6, 2023: International Journal of Obesity