Leiomyosarcoma of the skin. Treatment of 34 cases.

BACKGROUND: Leiomyosarcoma is a rare soft tissue sarcoma that is one of the least common malignant lesions found in the skin.

OBJECTIVE: We discuss the clinical, histopathologic, and prognostic factors related to superficial leiomyosarcoma from cases reported in the literature as well as from the Mayo Clinic experience from 1964 through 1994 with 34 patients.

CONCLUSIONS: The vast majority of tumors were treated by excisional surgery with wide margins, but conceptually, Mohs' micrographic surgery should prove useful for the treatment of this tumor as it has with other skin cancers displaying contiguous growth.