Association of a CYP3A5 gene polymorphism with exacerbation in adult patients with asthma.

Sekiko Uehara, Keita Hirai, Toshihiro Shirai, Kunihiko Itoh

Journal of Allergy and Clinical Immunology in Practice 2024 April 28

The CYP3A5*1 polymorphism, which increases the metabolic activity of CYP3A5, has been associated with a poor prognosis for asthma. In addition, individuals with this allele have a reduced response to corticosteroid treatment.

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Association of a CYP3A5 gene polymorphism with exacerbation in adult patients with asthma.

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