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Journals Journal of Allergy and Clinica...

Journal of Allergy and Clinical Immunology in Practice

https://read.qxmd.com/read/38796104/health-promotion-of-early-and-sustained-allergenic-food-introduction-for-the-prevention-of-food-allergy
#1
JOURNAL ARTICLE
Edward G A Iglesia, David M Fleischer, Elissa M Abrams
Observational studies and landmark randomized control trials support early and sustained allergenic food introduction in infancy as an effective preventive strategy against food allergy development. Despite a consensus regarding the intended goals of early and sustained allergenic food introduction, there have been myriad policy recommendations among health authorities in how to achieve both individual and population-level health outcomes for food allergy prevention. This clinical management review provides an overview on the data that informs early and sustained allergenic food introduction strategies, suggestions on how to advise allergenic food introduction, principles of prevention programs as they relate to food allergy prevention, and health promotion and systems-level challenges that impede achievement of food allergy prevention goals...
May 23, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38796103/the-association-of-asthma-and-metabolic-dysfunction-with-outcomes-of-hospitalized-patients-with-covid-19
#2
JOURNAL ARTICLE
Marija Vukoja, Aysun Tekin, Nereida A Parada, JaVaughn C Gray, Alan Mallouhi, Tiana Roddy, Rodrigo Cartin-Ceba, Nicholas E Perkins, Katherine A Belden, Sreekanth Cheruku, Margit Kaufman, Donna Lee Armaignac, Amy B Christie, Amos Lal, Yuanhao Zu, Vishakha Kumar, Allen Walkey, Ognjen Gajic, Rahul Kashyap, Joshua L Denson
BACKGROUND: There have been conflicting results on the association of asthma with the severity of COVID-19. Poor metabolic health has been previously associated with both severe COVID-19 and inflammation in asthma. OBJECTIVES: To examine the association between asthma and COVID-19 outcomes and if these associations are modified by metabolic syndrome. METHODS: We performed an international, observational cohort study of adult patients hospitalized for COVID-19 from March 2020 through October 2021...
May 23, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38796102/preserved-antibody-responses-to-covid-19-vaccination-and-lower-odds-of-developing-covid-19-in-adults-with-severe-asthma
#3
JOURNAL ARTICLE
Hitasha Rupani, Diane Edwards, Rekha Chaudhuri, Steven Smith, David J Jackson, Andrew Hearn, Jennifer Richards, Helen Moyses, Ramesh J Kurukulaaratchy, Hans Michael Haitchi, Michael R Edwards, Sebastian L Johnston, Ratko Djukanovic
No abstract text is available yet for this article.
May 23, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38796101/patient-reported-outcomes-in-asthma
#4
JOURNAL ARTICLE
Giselle Mosnaim, Michelle Carrasquel, Madeline Snedden, John Oppenheimer, David Lang, Melinda Rathkopf
The FDA's Center for Drug Evaluation and Research defines patient-reported outcomes (PROs) as "any report of the status of a patient's health condition, health behavior, or experience with healthcare that comes directly form the patient, without interpretation of the patient's response by a clinician or anyone else". Validated PRO measures are used extensively in pediatric and adult asthma across clinical and research settings to assess the impact of treatments on patient outcomes over time. This work aims to review some of the most commonly used asthma PROs across the following criteria: validity, reliability, responsiveness, time to complete, ease of administration, target population, recall period, scoring method, availability in different languages, use in clinical practice or research settings, licensing requirements, and cost of use...
May 23, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38796100/clinical-haematological-changes-and-predictors-of-severity-in-acute-food-protein-induced-enterocolitis-syndrome-reactions-at-oral-food-challenge-a-multicentre-observational-study
#5
JOURNAL ARTICLE
L Argiz, M Valsami-Fokianos, S Arasi, S Barni, S Boscia, G Bracaglia, T Bracamonte, I Carballeira, G Dinardo, L Echeverria, E Garcia, C Garcia-Magan, J Gomez-Rial, P Gonzalez-Delgado, A Fiocchi, T Garriga, T Ibrahim, S Infante, A Machinena, G Mangone, F Mori, J D Moure, V O'Valle, M Pascal, V Pecora, A Prieto, S Quevedo, A Salas-Ellacuriaga, S Vazquez-Cortes, L Vila, F Martinon-Torres, A Gomez-Carballa, R J Boyle, M Vazquez-Ortiz
BACKGROUND: Oral food challenge (OFC) is the gold standard for diagnosis of acute Food Protein-Induced Enterocolitis Syndrome (FPIES). No diagnostic/prognostic biomarkers are available, and OFC assessment criteria are not validated. OBJECTIVE: To assess clinical-haematological changes and predictors of severity of FPIES reactions at OFC. METHODS: Observational multicentre prospective study. Children aged 0-18 years diagnosed with acute FPIES were recruited at follow-up OFC in 12 tertiary centres in Spain and Italy...
May 23, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38777125/development-and-evaluation-of-modified-criteria-for-infant-and-toddler-anaphylaxis
#6
JOURNAL ARTICLE
Anna Handorf, Ian R Roy, Ari Cohen, Carlos A Camargo, Timothy E Dribin, Michael Pistiner
BACKGROUND: Current clinical criteria for identifying anaphylaxis do not account for unique aspects of infant anaphylaxis presentation and have not been validated in patients less than two years of age. This may contribute to under recognition and is thus an unmet need. OBJECTIVE: To demonstrate age-specific signs and symptoms that more accurately identify anaphylaxis in young children and to develop and compare modified criteria for "likely anaphylaxis" against the widely used 2006 National Institute of Allergy and Infectious Diseases / Food Allergy and Anaphylaxis Network criteria...
May 20, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38777124/characterization-of-moderate-and-severe-asthma-exacerbations-in-the-captain-study
#7
JOURNAL ARTICLE
John Oppenheimer, Huib A Kerstjens, Louis-Philippe Boulet, Nicola A Hanania, Edward Kerwin, Alison Moore, Robert A Nathan, Guy Peachey, Emilio Pizzichini, David Slade, Agne Zarankaite, Ian D Pavord
BACKGROUND: Limited data exist on the relative impact of moderate and severe exacerbations on asthma control and impairment. OBJECTIVE: To explore data from the CAPTAIN trial to evaluate the relationship between first moderate or severe exacerbation and changes in lung function, symptoms, physical activity limitation scores, and short-acting β2 -agonist (SABA) usage to determine the clinical relevance of moderate events. METHODS: CAPTAIN was a Phase IIIA 24-52-week, multicenter, international, randomized controlled trial evaluating efficacy and safety of fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) versus FF/VI in patients with uncontrolled asthma on inhaled corticosteroid/long-acting β2 -agonist...
May 20, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38768900/non-epithelial-gene-expression-correlates-with-symptom-severity-in-adults-with-eosinophilic-esophagitis
#8
JOURNAL ARTICLE
Seung Kim, Netali Ben-Baruch Morgenstern, Kasumi Osonoi, Seema S Aceves, Nicoleta C Arva, Mirna Chehade, Margaret H Collins, Evan S Dellon, Gary W Falk, Glenn T Furuta, Nirmala Prabhu Gonsalves, Sandeep K Gupta, Ikuo Hirano, Girish Hiremath, David A Katzka, Paneez Khoury, John Leung, Robbie Pesek, Kathryn A Peterson, Maria Pletneva, Jonathan M Spergel, Joshua B Wechsler, Guang-Yu Yang, Marc E Rothenberg, Tetsuo Shoda
BACKGROUND: The mechanistic basis of the variable symptomatology seen in eosinophilic esophagitis (EoE) remains poorly understood. OBJECTIVE: We examined the correlation of a validated, patient-reported outcome (PRO) metric with a broad spectrum of esophageal transcripts to uncover potential symptom pathogenesis. METHODS: Data were extracted from 146 adults with EoE through the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR)...
May 18, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38768899/-recognizing-and-managing-allergic-contact-dermatitis-focus-on-major-allergens
#9
JOURNAL ARTICLE
Luz Fonacier, Wolfgang Uter, Jeanne Duus Johansen
Patch testing is the gold standard for the diagnosis of allergic contact dermatitis. The identification and avoidance of culprit allergen/s is essential in the treatment of this disease. Each year, new allergens are identified as emerging or important. The authors discuss allergens that are common, enduring, emergent, incompletely recognized and controversial for the practicing allergist and dermatologist. This Clinical Management Review will encompass a review of fragrances, preservatives, rubber, acrylates, metals, and medications, their common sources of exposure, controversies in diagnosis and patch testing, management and how to avoid those allergens...
May 18, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38768898/a-novel-cutaneous-presentation-of-non-celiac-wheat-sensitivity
#10
JOURNAL ARTICLE
Larisa Epov, Nadira Musallam, Aharon Kessel
No abstract text is available yet for this article.
May 18, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38768897/diagnostic-accuracy-of-specific-ige-against-wheat-and-rye-in-flour-induced-occupational-asthma
#11
JOURNAL ARTICLE
Virginie Doyen, Nicolas Migueres, Alexandra Frère, Jolanta Walusiak-Skorupa, Marta Wiszniewska, Hille Suojalehto, Xavier Munoz, Christian Romero-Mesones, Vera van Kampen, Joaquin Sastre, Santiago Quirce, Pilar Barranco, Catherine Rifflart, Frédéric de Blay, Olivier Vandenplas
BACKGROUND: Assessment of IgE-mediated sensitization to flour allergens is widely used to investigate flour-induced occupational asthma. The diagnostic efficiency of detecting specific IgE antibodies (sIgE) against wheat and rye flour, however, has not been thoroughly compared to other diagnostic procedures. OBJECTIVE: We sought to evaluate the diagnostic accuracy of sIgE against wheat and rye compared to specific inhalation challenge (SIC) with flour as the reference standard...
May 18, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38768896/exploring-definitions-and-predictors-of-response-to-biologics-for-severe-asthma
#12
JOURNAL ARTICLE
Ghislaine Scelo, Trung N Tran, Tham T Le, Malin Faregås, Delbert Dorscheid, John Busby, Mona Al-Ahmad, Riyad Al-Lehebi, Alan Altraja, Aaron Beastall, Celine Bergeron, Leif Bjermer, Anne S Bjerrum, Diana Jimena Cano-Rosales, Giorgio Walter Canonica, Victoria Carter, Jeremy Charriot, George C Christoff, Borja G Cosio, Eve Denton, Maria Jose Fernandez-Sanchez, João A Fonseca, Peter G Gibson, Celine Goh, Liam G Heaney, Enrico Heffler, Mark Hew, Takashi Iwanaga, Rohit Katial, Mariko S Koh, Piotr Kuna, Désirée Larenas-Linnemann, Lauri Lehtimäki, Bassam Mahboub, Neil Martin, Hisako Matsumoto, Andrew N Menzies-Gow, Nikolaos G Papadopoulos, Pujan Patel, Luis Perez-De-Llano, Matthew Peters, Paul E Pfeffer, Todor A Popov, Celeste M Porsbjerg, Chin K Rhee, Mohsen Sadatsafavi, Camille Taillé, Carlos A Torres-Duque, Ming-Ju Tsai, Charlotte S Ulrik, John W Upham, Anna von Bülow, Eileen Wang, Michael E Wechsler, David B Price
BACKGROUND: Biologic effectiveness is often assessed as 'response', a term which eludes consistent definition. Identifying those most likely to respond in real-life has proven challenging. OBJECTIVE: To explore definitions of biologic responders in adults with severe asthma and investigate patient characteristics associated with biologic response. METHODS: This was a longitudinal cohort study using data from 21 countries, which shared data with the International Severe Asthma Registry...
May 18, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38768895/baricitinib-treatment-in-children-with-copa-syndrome
#13
JOURNAL ARTICLE
Caterina Matucci-Cerinic, Federica Corona, Giulia Camilla Varnier, Serena Pastore, Paola Bocca, Serena Palmeri, Angelo Ravelli, Roberta Caorsi, Marco Gattorno, Alberto Tommasini, Stefano Volpi
No abstract text is available yet for this article.
May 18, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38763464/parallel-remission-of-nsaid-exacerbated-cutaneous-reactions-and-chronic-spontaneous-urticaria
#14
JOURNAL ARTICLE
Jorge Sánchez, Susana Diez, Juan-Felipe Lopez
No abstract text is available yet for this article.
May 17, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38761861/evaluation-of-guidelines-line-care-approach-to-the-treatment-of-chronic-inducible-urticaria
#15
JOURNAL ARTICLE
J Sánchez, D Caraballo, D Amaya
BACKGROUND: Chronic Inducible Urticaria (CIndU) management often follows Chronic Spontaneous Urticaria (CSU) guidelines, but a step-by-step evaluation of their effectiveness in CIndU is lacking. OBJECTIVE: To assess the clinical impact of adapting CSU international guidelines for CIndU management. METHODS: We conducted a prospective cohort study involving patients diagnosed with CIndU based on challenge tests and a Urticaria Control Test (UCT) score of <11 points...
May 16, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38761860/how-allergists-can-perform-an-occupational-history-in-every-patient
#16
JOURNAL ARTICLE
David I Bernstein, Karin Pacheco, Catherine Lemiere
The occupational history is often neglected in the routine evaluation of new patients with asthma, chronic rhinitis or dermatologic complaints. Such omissions are inadvertent because work related conditions are often not prioritized. There also may be lack of awareness of the scope of respiratory or cutaneous allergens capable of inducing occupational asthma (OA) or work-related contact dermatitis. Evidence exists suggesting that the occupational history is often neglected among primary care physicians and specialists...
May 16, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38759791/asthma-is-associated-with-increased-sickness-absence-among-young-adults
#17
JOURNAL ARTICLE
Sandra Ekström, Julio C Hernando-Rodriguez, Niklas Andersson, Chantelle Murley, Victoria Mailen Arfuch, Anne-Sophie Merritt, Christer Janson, Theo Bodin, Gun Johansson, Inger Kull
BACKGROUND: There is limited knowledge about how asthma affects sickness absence in young adulthood. OBJECTIVE: To examine how asthma and different asthma phenotypes affect sickness absence among young adults and potential modifying factors. A secondary aim was to estimate productivity losses related to sickness absence for asthma. METHODS: The study included 2,391 participants from the Swedish population-based cohort BAMSE. Information on asthma, asthma phenotypes, and lifestyle factors were collected from questionnaires and clinical examinations at ∼24 years of age (2016-2019)...
May 15, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38759790/food-sublingual-immunotherapy-safety-and-simplicity-of-a-real-food-updosing-protocol
#18
JOURNAL ARTICLE
Reed R Windom, Samantha Seitz, Jean B Ly, Neha Dunn, Jennifer Fergeson, Hugh H Windom
BACKGROUND: Sublingual immunotherapy (SLIT) using food extracts is safe and effective in desensitizing food allergy patients yet not often used in clinical practice. OBJECTIVES: We propose a cost-effective, expedited SLIT protocol using real food. METHODS: Food allergy patients 5-50 years, median 11, initiated food SLIT in a single clinic setting. The daily maintenance dose was 4-11 mg protein in 0.1-0.5 ml volume, depending on the food. Some foods were available in liquid form at the local grocery (milk, egg white liquid, and cashew/walnut/sunflower/hazelnut milk), while others were prepared in the office using flour and 50% glycerin saline (peanut/sesame/wheat)...
May 15, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38734374/association-of-novel-antihyperglycemic-drugs-versus-metformin-with-decrease-in-asthma-exacerbations
#19
JOURNAL ARTICLE
Yuya Kimura, Taisuke Jo, Norihiko Inoue, Maho Suzukawa, Yohei Hashimoto, Ryosuke Kumazawa, Miho Ishimaru, Hiroki Matsui, Akira Yokoyama, Goh Tanaka, Yusuke Sasabuchi, Hideo Yasunaga
BACKGROUND: Similar to metformin, dipeptidyl peptidase-4 inhibitors (DPP-4 Is), glucagon-like peptidase 1 receptor agonists (GLP-1 RAs), and sodium glucose co-transporter-2 inhibitors (SGLT-2 Is) may improve control of asthma owing to their multiple potential mechanisms, including differential improvements in glycemic control, direct anti-inflammatory effects, and systemic changes in metabolism. OBJECTIVE: To investigate whether these novel antihyperglycemic drugs were associated with fewer asthma exacerbations compared with metformin in patients with asthma comorbid with type 2 diabetes...
May 9, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38734373/improving-clinical-practice-through-patient-registries-in-allergy-and-immunology
#20
JOURNAL ARTICLE
Andrew Moore, Kimberly G Blumenthal, Christina Chambers, Jennifer Namazy, Anna Nowak-Wegrzyn, Elizabeth J Phillips, Nicholas L Rider
Patient registries are a mechanism for collecting data on allergic and immunologic diseases that provide important information on epidemiology and outcomes that can ultimately improve patient care. Key criteria for establishing effective registries include the use of a clearly defined purpose, identifying the target population and ensuring consistent data collection. Registries in allergic diseases include those for diseases such as inborn errors of immunity, food allergy, asthma and anaphylaxis, pharmacological interventions in vulnerable populations, and adverse effects of pharmacologic interventions including hypersensitivity reactions to drugs and vaccines...
May 9, 2024: Journal of Allergy and Clinical Immunology in Practice
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