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Therapeutic intersections: Expanding benefits of CD19 CAR T cells from cancer to autoimmunity.
Cell Stem Cell 2024 April 5
Anti-CD19 CAR T cells were among the last decade's scientific breakthroughs, achieving remarkable remissions in patients with B cell leukemias and lymphomas. Now, the engineered cell therapies are traversing disease indications into autoimmunity and resolving disease symptoms in patients with systemic lupus erythematosus (SLE), idiopathic inflammatory myositis, and systemic sclerosis.1 .
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