Ivan Pavlov, Jie Li, Aileen Kharat, Jian Luo, Miguel Ibarra-Estrada, Yonatan Perez, Bairbre McNicolas, Daniele Poole, Oriol Roca, David Vines, Elsa Tavernier, Thérèse Allen, Murali Shyamsundar, Stephan Ehrmann, Steven Q Simpson, Claude Guérin, John G Laffey
BACKGROUND: Awake prone positioning (APP) of non-intubated patients with acute hypoxaemic respiratory failure (AHRF) has been inconsistently adopted into routine care of patients with COVID-19, likely due to apparent conflicting evidence from recent trials. This short guideline aims to provide evidence-based recommendations for the use of APP in various clinical scenarios. METHODS: An international multidisciplinary panel, assembled for their expertise and representativeness, and supported by a methodologist, performed a systematic literature search, summarized the available evidence derived from randomized clinical trials, and developed recommendations using GRADE (Grading of Recommendations, Assessment, Development, and Evaluation) methodology...
August 26, 2023: Journal of Critical Care