journal
https://read.qxmd.com/read/38423934/trust-in-the-icu-what-every-clinician-should-know
#21
REVIEW
Abdul W Kazi, Erika J Yoo, David Oxman
Trust is an essential element in the relationship between patients and intensive care unit (ICU) clinicians. Without a foundation of trust, communication is difficult, conflict is more likely, and even clinical outcomes can be affected. The ICU is a particularly challenging environment for trust to flourish. Illness occurs suddenly, emotions can be charged, the environment is impersonal, and there is rarely a prior relationship between patients and their caregivers. Therefore, intensivists must have some understanding of the factors that impact patient and family trust, as well as the actions they can take to improve it...
February 28, 2024: Journal of Critical Care
https://read.qxmd.com/read/38402748/plasma-sodium-during-the-recovery-of-renal-function-in-critically-ill-adult-patients-multicenter-prospective-cohort-study
#22
JOURNAL ARTICLE
Natalia Alejandra Angeloni, Irene Outi, Monica Alejandra Alvarez, Sofia Sterman, Julio Fernandez Morales, Fabio Daniel Masevicius
BACKGROUND: Sodium increases during acute kidney injury (AKI) recovery. Both hypernatremia and positive fluid balances are associated with increased mortality. We aimed to evaluate the association between daily fluid balance and daily plasma sodium during the recovery from AKI among critical patients. METHODS: Adult patients with AKI were enrolled in four ICUs and followed up for four days or until ICU discharge or hemodialysis initiation. Day zero was the peak day of creatinine...
February 24, 2024: Journal of Critical Care
https://read.qxmd.com/read/38395004/brain-death-determination-in-patients-with-veno-arterial-extracorporeal-membrane-oxygenation-a-systematic-study-to-address-the-harlequin-syndrome
#23
JOURNAL ARTICLE
Farid Salih, Johann Lambeck, Albrecht Günther, Caroline Ferse, Olaf Hoffmann, Konstantinos Dimitriadis, Andre Finn, Stephan A Brandt, Benjamin Hotter, Florian Masuhr, Stephan Schreiber, Florian Weissinger, Andrea Rocco, Hauke Schneider, Wolf-Dirk Niesen
PURPOSE: The Harlequin syndrome may occur in patients treated with venoarterial extracorporal membrane oxygenation (VA-ECMO), in whom blood from the left ventricle and the ECMO system supply different parts of the body with different pa CO2 -levels. The purpose of this study was to compare two variants of pa CO2 -analysis to account for the Harlequin syndrome during apnea testing (AT) in brain death (BD) determination. MATERIALS AND METHODS: Twenty-seven patients (median age 48 years, 26-76 years; male n = 19) with VA-ECMO treatment were included who underwent BD determination...
February 22, 2024: Journal of Critical Care
https://read.qxmd.com/read/38382208/letter-to-editor-management-of-swallowing-disorders-in-icu-patients-a-multinational-expert-opinion
#24
LETTER
Musa Baklaci, Sibel Eyigor
No abstract text is available yet for this article.
February 20, 2024: Journal of Critical Care
https://read.qxmd.com/read/38382207/letter-to-the-editor-effects-of-structured-protocolized-physical-therapy-on-the-duration-of-mechanical-ventilation-in-patients-with-prolonged-weaning
#25
LETTER
Tugba Ozudogru Celik
No abstract text is available yet for this article.
February 20, 2024: Journal of Critical Care
https://read.qxmd.com/read/38367526/practices-surrounding-antimicrobial-use-in-patients-managed-with-extracorporeal-membrane-oxygenation-an-international-survey
#26
JOURNAL ARTICLE
Atul Dilawri, Justin Muir, Daniel Brodie, Darryl Abrams, Cara Agerstrand, Purnema Madahar, Amy L Dzierba
PURPOSE: This study aimed to survey critical care clinicians and characterize their perception of antimicrobial dosing strategies in patients receiving extracorporeal membrane oxygenation (ECMO). METHODS: International, cross-sectional survey distributed to members of the Society of Critical Care Medicine in October 2022. RESULTS: Respondents were primarily physicians (45%), with 92% practicing in North America. Ninety-seven percent of respondents reported antimicrobial dosing in critically ill patients to be challenging, due to physiological derangements seen in the patient population...
February 16, 2024: Journal of Critical Care
https://read.qxmd.com/read/38364665/malglycemia-in-the-critical-care-setting-part-iii-temporal-patterns-relative-potencies-and-hospital-mortality
#27
JOURNAL ARTICLE
Gregory W Roberts, James S Krinsley, Jean-Charles Preiser, Stephen Quinn, Peter R Rule, Michael Brownlee, Guillermo E Umpierrez, Irl B Hirsch
INTRODUCTION: The relationship between critical care mortality and combined impact of malglycemia remains undefined. METHODS: We assessed the risk-adjusted relationship (n = 4790) between hospital mortality with malglycemia, defined as hypergycemia (hours Glycemic Ratio ≥ 1.1, where GR is quotient of mean ICU blood glucose (BG) and estimated average BG), absolute hypoglycemia (hours BG < 70 mg/dL) and relative hypoglycemia (excursions GR < 0...
February 15, 2024: Journal of Critical Care
https://read.qxmd.com/read/38359518/immunologic-effect-and-clinical-impact-of-erythromycin-in-septic-patients-a-randomized-clinical-trial
#28
JOURNAL ARTICLE
Ahlem Trifi, Badis Tlili, Maryam Kallel Sellami, Moncef Feki, Asma Mehdi, Eya Seghir, Lynda Messaoud, Sami Abdellatif, Salah Ben Lakhal
To investigate the potential regulatory effect of erythromycin added to standard care in septic patients on sepsis biomarkers and clinical outcome. It was a single-blind randomized trial including critical septic patients. The primary endpoint was the change in the TNF/IL-10 ratio between days 0 and 6. Changes in other biomarkers, vasopressor use, and 28-day mortality were secondary endpoints. One hundred and ten patients were examined (erythromycin group, n = 55 versus placebo group, n = 55)...
February 14, 2024: Journal of Critical Care
https://read.qxmd.com/read/38359517/letter-to-the-editor-resuscitative-transesophageal-echocardiography-during-the-acute-resuscitation-of-trauma-a-retrospective-observational-study
#29
LETTER
Libing Jiang, Hongyu Zhang
No abstract text is available yet for this article.
February 14, 2024: Journal of Critical Care
https://read.qxmd.com/read/38354622/diagnostic-value-of-procalcitonin-c-reactive-protein-to-lymphocyte-ratio-clr-c-reactive-protein-and-neutrophil-to-lymphocyte-ratio-nlr-for-predicting-patients-with-bacteraemia-in-the-intensive-care-unit
#30
JOURNAL ARTICLE
Guo-Ming Zhang, Yuan-Yuan Gu
BACKGROUND: To explore the diagnostic value of procalcitonin (PCT), C-reactive protein-to-lymphocyte ratio (CLR), C-reactive protein (CRP) and neutrophil-to-lymphocyte ratio (NLR) for predicting patients with bacteremia in the intensive care unit (ICU). METHODS: This case-control study included 359 patients with suspected bacteremia were divided into a bacteremia group (n = 152) and a control group (n = 207) from September 2018 to April 2023...
February 13, 2024: Journal of Critical Care
https://read.qxmd.com/read/38341938/different-ventilation-intensities-among-various-categories-of-patients-ventilated-for-reasons-other-than-ards-a-pooled-analysis-of-4-observational-studies
#31
JOURNAL ARTICLE
Simon Corrado Serafini, David M P van Meenen, Luigi Pisani, Ary Serpa Neto, Lorenzo Ball, Marcelo Gama de Abreu, Anna Geke Algera, Luciano Azevedo, Giacomo Bellani, Arjen M Dondorp, Eddy Fan, John G Laffey, Tai Pham, Edda M Tschernko, Marcus J Schultz, Margaretha C E van der Woude
PURPOSE: We investigated driving pressure (ΔP) and mechanical power (MP) and associations with clinical outcomes in critically ill patients ventilated for reasons other than ARDS. MATERIALS AND METHODS: Individual patient data analysis of a pooled database that included patients from four observational studies of ventilation. ΔP and MP were compared among invasively ventilated non-ARDS patients with sepsis, with pneumonia, and not having sepsis or pneumonia...
February 10, 2024: Journal of Critical Care
https://read.qxmd.com/read/38335863/inside-the-black-box-random-effects-meta-analysis-with-zero-heterogeneity
#32
LETTER
Thomas Payne, John A Loadsman
No abstract text is available yet for this article.
February 8, 2024: Journal of Critical Care
https://read.qxmd.com/read/38335862/measurements-of-i-fabp-and-citrulline-in-the-postoperative-period-of-non-cardiac-surgeries-with-gastrointestinal-complications-a-prospective-cohort-observational-study
#33
JOURNAL ARTICLE
Eduarda Tebet Ajeje, Joelma Villafanha Gandolfi, Vinicius Cavallari, João Manoel Silva-Jr, Renato Carneiro de Freitas Chaves, Joana Berger-Estilita, Suzana Margareth Lobo
BACKGROUND: Acute Gastrointestinal Injury (AGI) is associated with adverse clinical outcomes, including increased mortality. We aimed to investigate the potential of citrulline and intestinal fatty acid binding protein (I-FABP) as biomarkers for early AGI diagnosis and predicting outcomes in surgical patients. METHODS: Prospective cohort study involving patients who underwent non-cardiac surgeries and were admitted to Intensive Care Units. AGI diagnosis was based on specific criteria, and severity was categorised following established guidelines...
February 8, 2024: Journal of Critical Care
https://read.qxmd.com/read/38330737/hemodynamic-profile-of-cirrhotic-patients-with-sepsis-and-septic-shock-a-propensity-score-matched-case-control-study
#34
JOURNAL ARTICLE
Jee Young You, Ryota Sato, Sanchit Chawla, Aanchal Kapoor, Xiaofeng Wang, Patrick Collier, Georg Auzinger, Abhijit Duggal, Siddharth Dugar
PURPOSE: Our understanding of hemodynamics in cirrhotic patients with sepsis remains limited. Our study aims to investigate differences in hemodynamic profiles using echocardiography between septic patients with and without cirrhosis. MATERIALS AND METHODS: This is a single-center, retrospective study of septic patients with echocardiogram within 3 days of ICU admission. We compared baseline characteristics, echocardiographic markers of LV systolic function arterial load between patients with and without cirrhosis...
February 7, 2024: Journal of Critical Care
https://read.qxmd.com/read/38295627/acute-kidney-injury-in-patients-before-and-after-extracorporeal-membrane-oxygenation-ecmo-retrospective-longitudinal-analysis-of-the-hospital-outcomes
#35
JOURNAL ARTICLE
Pramod K Guru, Prasanth Balasubramanian, Manoj Ghimire, J Kyle K Bohman, Troy G Seelhammer, Kianoush B Kashani, Gregory J Schears
PURPOSE: Acute Kidney Injury (AKI) occurs in up to 85% of patients managed by ECMO support. Limited data are available comparing the outcomes among patients who develop AKI before and after ECMO initiation. METHODS: A retrospective longitudinal observational study was performed on all adult patients placed on ECMO from January 2000 to December 2015 at our institution. Longitudinal multivariate logistic regressional analysis was performed to identify the variables that are associated with the outcome measures (post-ECMO AKI and in-hospital mortality)...
January 30, 2024: Journal of Critical Care
https://read.qxmd.com/read/38272771/letter-to-the-editor-prospective-evaluation-of-bleeding-risk-among-thrombocytopenic-patients-admitted-in-intensive-care-unit
#36
LETTER
Ahmad Nasir Wasiq, Sadia Saeed
No abstract text is available yet for this article.
January 24, 2024: Journal of Critical Care
https://read.qxmd.com/read/38272770/response-to-letter-to-the-editor-prospective-evaluation-of-bleeding-risk-among-thrombocytopenic-patients-admitted-in-intensive-care-unit
#37
LETTER
Geoffroy Hariri, Tomas Urbina, Hafid Ait-Oufella
No abstract text is available yet for this article.
January 24, 2024: Journal of Critical Care
https://read.qxmd.com/read/38237203/implementing-an-icu-registry-in-ethiopia-implications-for-critical-care-quality-improvement
#38
JOURNAL ARTICLE
Menbeu Sultan, Ayalew Zewdie, Dilanthi Priyadarshani, Ephrem Hassen, Melkamu Tilahun, Tigist Geremew, Abi Beane, Rashan Haniffa, Sean M Berenholtz, William Checkley, Bhakti Hansoti, Adam D Laytin
PURPOSE: Intensive care units (ICUs) in low- and middle-income countries have high mortality rates, and clinical data are needed to guide quality improvement (QI) efforts. This study utilizes data from a validated ICU registry specially developed for resource-limited settings to identify evidence-based QI priorities for ICUs in Ethiopia. MATERIALS AND METHODS: A retrospective cohort analysis of data from two tertiary referral hospital ICUs in Addis Ababa, Ethiopia from July 2021-June 2022 was conducted to describe casemix, complications and outcomes and identify features associated with ICU mortality...
January 17, 2024: Journal of Critical Care
https://read.qxmd.com/read/38199062/multicentre-implementation-of-a-quality-improvement-initiative-to-reduce-delirium-in-adult-intensive-care-units-an-interrupted-time-series-analysis
#39
JOURNAL ARTICLE
Victoria S Owen, Selvi Sinnadurai, Jeanna Morrissey, Heather Colaco, Patty Wickson, Donalda Dyjur, Melissa Redlich, Barbara O'Neill, David A Zygun, Christopher J Doig, Jo Harris, Danny J Zuege, Henry T Stelfox, Peter D Faris, Kirsten M Fiest, Daniel J Niven
PURPOSE: The ABCDEF bundle may improve delirium outcomes among intensive care unit (ICU) patients, however population-based studies are lacking. In this study we evaluated effects of a quality improvement initiative based on the ABCDEF bundle in adult ICUs in Alberta, Canada. MATERIAL AND METHODS: We conducted a pre-post, registry-based clinical trial, analysed using interrupted time series methodology. Outcomes were examined via segmented linear regression using mixed effects models...
January 9, 2024: Journal of Critical Care
https://read.qxmd.com/read/38194760/continuous-renal-replacement-therapy-and-survival-in-acute-liver-failure-a-systematic-review-and-meta-analysis
#40
JOURNAL ARTICLE
Victor Dong, Andrea M Robinson, Joanna C Dionne, Filipe S Cardoso, Oleksa G Rewa, Constantine J Karvellas
OBJECTIVE: Acute liver failure (ALF) is a rare syndrome leading to significant morbidity and mortality. An important cause of mortality is cerebral edema due to hyperammonemia. Different therapies for hyperammonemia have been assessed including continuous renal replacement therapy (CRRT). We conducted a systematic review and meta-analysis to determine the efficacy of CRRT in ALF patients. MATERIALS AND METHODS: We searched MEDLINE, EMBASE, Cochrane Library, and Web of Science...
January 8, 2024: Journal of Critical Care
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