journal
https://read.qxmd.com/read/38565454/what-every-intensivist-should-know-about-quality-of-life-after-critical-illness
#21
LETTER
Marieke Zegers, Lucy Porter, Koen Simons, Mark van den Boogaard
No abstract text is available yet for this article.
April 1, 2024: Journal of Critical Care
https://read.qxmd.com/read/38555684/multimodal-monitoring-in-patients-with-acute-brain-injury-a-survey-from-critical-care-providers
#22
JOURNAL ARTICLE
Dana Klavansky, Raquel Romero, Neha S Dangayach, Sarah E Nelson, John Liang, Alexandra Reynolds, Spyridoula Tsetsou
BACKGROUND: Multimodal neuromonitoring (MMM) aims to improve outcome after acute brain injury, and thus admission in specialized Neurocritical Care Units with potential access to MMM is necessary. Various invasive and noninvasive modalities have been developed, however there is no strong evidence to support monitor combinations nor is there a known standardized approach. The goal of this study is to identify the most used invasive and non-invasive neuromonitoring modalities in daily practice as well as ubiquitousness of MMM standardization...
March 30, 2024: Journal of Critical Care
https://read.qxmd.com/read/38555251/authors-response-brain-magnetic-resonance-imaging-findings-six-months-after-critical-covid-19-a-prospective-cohort-study
#23
LETTER
Henriikka Ollila, Janne Pihlajamaa, Juha Martola, Laura Hokkanen, Marjaana Tiainen, Johanna Hästbacka
No abstract text is available yet for this article.
March 30, 2024: Journal of Critical Care
https://read.qxmd.com/read/38554544/limitations-of-life-sustaining-therapies-in-south-africa
#24
JOURNAL ARTICLE
Charles Feldman, Gavin M Joynt, Spyros D Mentzelopoulos, Charles L Sprung, Alexander Avidan, Guy A Richards
PURPOSE: Limitations of life sustaining therapies (LLST) are frequent in intensive care units (ICUs), but no previous studies have examined end-of-life (EOL) care and LLST in South Africa (SA). MATERIALS AND METHODS: This study evaluated LLST in SA from the data of a prospective, international, multicentre, observational study (Ethicus-2) and compared practices with countries in the rest of the world. RESULTS: LLST was relatively common in SA, and withholding was more frequent than withdrawing therapy...
March 29, 2024: Journal of Critical Care
https://read.qxmd.com/read/38554543/artificial-intelligence-and-machine-learning-definition-of-terms-and-current-concepts-in-critical-care-research
#25
JOURNAL ARTICLE
Kai Sun, Arkajyoti Roy, Joshua M Tobin
With increasing computing power, artificial intelligence (AI) and machine learning (ML) have prospered, which facilitate the analysis of large datasets, especially those found in critical care. It is important to define these terminologies, to inform a standardized approach to critical care research. This manuscript hopes to clarify these terms with examples from medical literature. Three major components that are required for a successful ML implementation: (i) reliable dataset, (ii) ML algorithm, and (iii) unbiased model evaluation, are discussed...
March 29, 2024: Journal of Critical Care
https://read.qxmd.com/read/38553353/what-every-intensivist-should-know-about-patient-safety-huddles-in-the-icu
#26
JOURNAL ARTICLE
Margo Hoyler, Michael S Niederman, Natalia Ivascu Girardi
Patient safety huddles are brief, multidisciplinary conversations that focus on a specific topic or event. Huddles have been shown to improve communication among healthcare providers in a variety of settings, including the intensive care unit (ICU). This paper presents key features of patient safety huddles and describes the ways in which huddle techniques may be particularly relevant to the practice of critical care.
March 29, 2024: Journal of Critical Care
https://read.qxmd.com/read/38553352/authors-response-heart-involvement-a-neglected-manifestation-of-haemophagocytic-syndrome-associated-with-high-mortality
#27
LETTER
Olivier Lambotte
No abstract text is available yet for this article.
March 28, 2024: Journal of Critical Care
https://read.qxmd.com/read/38552452/automatic-ards-surveillance-with-chest-x-ray-recognition-using-convolutional-neural-networks
#28
JOURNAL ARTICLE
Run Zhou Ye, Kirill Lipatov, Daniel Diedrich, Anirban Bhattacharyya, Bradley J Erickson, Brian W Pickering, Vitaly Herasevich
OBJECTIVE: This study aims to design, validate and assess the accuracy a deep learning model capable of differentiation Chest X-Rays between pneumonia, acute respiratory distress syndrome (ARDS) and normal lungs. MATERIALS AND METHODS: A diagnostic performance study was conducted using Chest X-Ray images from adult patients admitted to a medical intensive care unit between January 2003 and November 2014. X-ray images from 15,899 patients were assigned one of three prespecified categories: "ARDS", "Pneumonia", or "Normal"...
March 28, 2024: Journal of Critical Care
https://read.qxmd.com/read/38552451/minimizing-bias-when-using-artificial-intelligence-in-critical-care-medicine
#29
JOURNAL ARTICLE
Benjamin L Ranard, Soojin Park, Yugang Jia, Yiye Zhang, Fatima Alwan, Leo Anthony Celi, Elizabeth R Lusczek
No abstract text is available yet for this article.
March 28, 2024: Journal of Critical Care
https://read.qxmd.com/read/38552450/the-impact-of-aggressive-and-conservative-propensity-for-initiation-of-neuromuscular-blockade-in-mechanically-ventilated-patients-with-hypoxemic-respiratory-failure
#30
JOURNAL ARTICLE
Zach Shahn, Boris Jung, Daniel Talmor, Edward H Kennedy, Li-Wei H Lehman, Elias Baedorf-Kassis
INTRODUCTION: Neuromuscular blockade (NMB) in ventilated patients may cause benefit or harm. We applied "incremental interventions" to determine the impact of altering NMB initiation aggressiveness. METHODS: Retrospective cohort study of ventilated patients with PaO2/FiO2 ratio < 150 mmHg and PEEP≥ 8cmH2O from the Medical Information Mart of Intensive Care IV database (MIMIC-IV version 1.0) estimating the effect of incremental interventions on in-hospital mortality and ventilator-free days, modifying hourly propensity for NMB initiation to be aggressive or conservative relative to usual care, adjusting for confounding with inverse probability weighting...
March 28, 2024: Journal of Critical Care
https://read.qxmd.com/read/38548515/development-and-validation-of-potential-phenotypes-of-serum-electrolyte-disturbances-in-critically-ill-patients-and-a-web-based-application
#31
JOURNAL ARTICLE
Wenyan Xiao, Lisha Huang, Heng Guo, Wanjun Liu, Zhang Jin, Yu Liu, Hua Tianfeng, Min Yang
BACKGROUND: Electrolyte disturbances are highly heterogeneous and severely affect the prognosis of critically ill patients. Our study was to determine whether data-driven phenotypes of seven electrolytes have prognostic relevance in critically ill patients. METHODS: We extracted patient information from three large independent public databases, and clustered the electrolyte distribution of ICU patients based on the extreme value, median value and coefficient of variation of electrolytes...
March 28, 2024: Journal of Critical Care
https://read.qxmd.com/read/38538503/response-letter-to-a-letter-for-the-editor-a-modified-delphi-process-to-identify-rank-and-prioritize-quality-indicators-for-continuous-renal-replacement-therapy-crrt-care-in-critically-ill-patients-and-quality-of-care-and-safety-measures-of-acute-renal-replacement
#32
LETTER
https://read.qxmd.com/read/38538502/letter-to-the-editor-brain-magnetic-resonance-imaging-findings-six-months-after-critical-covid-19-a-prospective-cohort-study
#33
LETTER
Muhammad Rafay Shahzad Cheema
No abstract text is available yet for this article.
March 26, 2024: Journal of Critical Care
https://read.qxmd.com/read/38537526/a-shift-towards-targeted-post-icu-treatment-multidisciplinary-care-for-cardiac-arrest-survivors
#34
JOURNAL ARTICLE
George E Sayde, Peter A Shapiro, Ian Kronish, Sachin Agarwal
Intensive Care Unit (ICU) survivorship comprises a burgeoning area of critical care medicine, largely due to our improved understanding of and concern for patients' recovery trajectory, and efforts to mitigate the post-acute complications of critical illness. Expansion of care beyond hospitalization is necessary, yet evidence for post-ICU clinics remains limited and mixed, as both interventions and target populations studied to date are too heterogenous to meaningfully demonstrate efficacy. Here, we briefly present the existing evidence and limitations related to post-ICU clinics, identify cardiac arrest survivors as a unique ICU subpopulation warranting further investigation and treatment, and propose a clinical framework that addresses the multifaceted needs of this well-defined patient population...
March 26, 2024: Journal of Critical Care
https://read.qxmd.com/read/38531748/development-of-a-machine-learning-model-for-prediction-of-the-duration-of-unassisted-spontaneous-breathing-in-patients-during-prolonged-weaning-from-mechanical-ventilation
#35
JOURNAL ARTICLE
Sebastian Johannes Fritsch, Morris Riedel, Gernot Marx, Johannes Bickenbach, Andreas Schuppert
PURPOSE: Treatment of patients undergoing prolonged weaning from mechanical ventilation includes repeated spontaneous breathing trials (SBTs) without respiratory support, whose duration must be balanced critically to prevent over- and underload of respiratory musculature. This study aimed to develop a machine learning model to predict the duration of unassisted spontaneous breathing. MATERIALS AND METHODS: Structured clinical data of patients from a specialized weaning unit were used to develop (1) a classifier model to qualitatively predict an increase of duration, (2) a regressor model to quantitatively predict the precise duration of SBTs on the next day, and (3) the duration difference between the current and following day...
March 26, 2024: Journal of Critical Care
https://read.qxmd.com/read/38531749/artificial-intelligence-and-machine-learning-in-critical-care-research
#36
JOURNAL ARTICLE
Joshua M Tobin, Elizabeth Lusczek, Jan Bakker
No abstract text is available yet for this article.
March 25, 2024: Journal of Critical Care
https://read.qxmd.com/read/38522373/telemedicine-critical-care-availability-and-outcomes-among-mechanically-ventilated-patients
#37
JOURNAL ARTICLE
Jonah M Graves, James G Krings, Joanna L Buss, Dorina Kallogjeri, Uchenna R Ofoma
PURPOSE: Telemedicine Critical Care (TCC) improves adherence to evidence based protocols associated with improved mortality among patients receiving invasive mechanical ventilation (IMV). We sought to evaluate the relationship between hospital availability of TCC and outcomes among patients receiving IMV. MATERIALS AND METHODS: We performed a cross-sectional study of 66,522 adults who received IMV for non-postoperative acute respiratory failure at 318 non-federal hospitals in New York, Massachusetts, Maryland, and Florida in 2018...
March 23, 2024: Journal of Critical Care
https://read.qxmd.com/read/38507842/eleven-years-impact-of-a-stepwise-educational-program-on-healthcare-associated-infections-and-antibiotics-consumption-in-an-intensive-care-unit-of-a-tertiary-hospital-in-brazil
#38
JOURNAL ARTICLE
Jakeline Neves Giovanetti, Pedro Henrique Della Libera, Matheus Liguori Feliciano da Silva, Ícaro Boszczowski, Luis Carlos Maia Cardozo Junior, Yuri de Albuquerque Pessoa Dos Santos, Daniel Neves Forte, Raquel de Nardi, Rogerio Zigaib, Marcelo Park
BACKGROUND: Hospital acquired infections (HAI) and liberal use of broad-spectrum antibiotics are common in intensive care unit(ICU)s of low-middle income countries. We investigated the long-term association of a stepwise multifaceted educational program with the incidence of HAIs and antibiotics use in a Brazilian ICU. We also evaluated the program's cost impact. METHODS: We retrieved data from a prospective daily collected database of a twelve bedrooms ICU, all admitted patients within a period of eleven years were enrolled...
March 19, 2024: Journal of Critical Care
https://read.qxmd.com/read/38503008/determining-steady-state-trough-range-in-vancomycin-drug-dosing-using-machine-learning
#39
JOURNAL ARTICLE
M Samie Tootooni, Erin F Barreto, Phichet Wutthisirisart, Kianoush B Kashani, Kalyan S Pasupathy
BACKGROUND: Vancomycin is a renally eliminated, nephrotoxic, glycopeptide antibiotic with a narrow therapeutic window, widely used in intensive care units (ICU). We aimed to predict the risk of inappropriate vancomycin trough levels and appropriate dosing for each ICU patient. METHODS: Observed vancomycin trough levels were categorized into sub-therapeutic, therapeutic, and supra-therapeutic levels to train and compare different classification models. We included adult ICU patients (≥ 18 years) with at least one vancomycin concentration measurement during hospitalization at Mayo Clinic, Rochester, MN, from January 2007 to December 2017...
March 18, 2024: Journal of Critical Care
https://read.qxmd.com/read/38493531/sex-disparities-in-cardiogenic-shock-insights-from-the-frenshock-registry
#40
JOURNAL ARTICLE
Stéphane Manzo-Silberman, Anne-Céline Martin, Florence Boissier, Caroline Hauw-Berlemont, Nadia Aissaoui, Nicolas Lamblin, François Roubille, Eric Bonnefoy, Laurent Bonello, Meyer Elbaz, Guillaume Schurtz, Olivier Morel, Guillaume Leurent, Bruno Levy, Bernard Jouve, Brahim Harbaoui, Gérald Vanzetto, Nicolas Combaret, Benoit Lattucca, Sébastien Champion, Pascal Lim, Cédric Bruel, Francis Schneider, Marie-France Seronde, Vincent Bataille, Edouard Gerbaud, Etienne Puymirat, Clément Delmas
BACKGROUND: Cardiogenic shock (CS) is the most severe form of acute heart failure. Discrepancies have been reported between sexes regarding delays, pathways and invasive strategies in CS complicating acute myocardial infarction. However, effect of sex on the prognosis of unselected CS remains controversial. OBJECTIVES: The aim was to analyze the impact of sex on aetiology, management and prognosis of CS. METHODS: The FRENSHOCK registry included all CS admitted in 49 French Intensive Care Units (ICU) and Intensive Cardiac Care Units (ICCU) between April and October 2016...
March 16, 2024: Journal of Critical Care
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