journal
https://read.qxmd.com/read/37923617/authors-response-association-of-plasma-volume-status-with-outcomes-in-hospitalized-covid-19-ards-patients-a-retrospective-multicenter-observational-study
#21
LETTER
Shahin Isha, Prasanth Balasubramanian, Devang K Sanghavi
No abstract text is available yet for this article.
November 2, 2023: Journal of Critical Care
https://read.qxmd.com/read/37922813/letters-to-editor-association-of-plasma-volume-status-with-outcomes-in-hospitalized-covid-19-ards-patients-a-retrospective-multicenter-observational-study
#22
LETTER
https://read.qxmd.com/read/37918129/the-safety-and-efficacy-of-stem-cells-for-the-treatment-of-severe-community-acquired-bacterial-pneumonia-a-randomized-clinical-trial
#23
JOURNAL ARTICLE
Pierre-François Laterre, Miguel Sánchez García, Tom van der Poll, Xavier Wittebole, Fernando Martínez-Sagasti, Gonzalo Hernandez, Ricard Ferrer, Jesus Caballero, Kathy-Ann Cadogan, Adam Sullivan, Barbara Zhang, Olga de la Rosa, Eleuterio Lombardo, Bruno François
PURPOSE: Evaluate the safety profile of expanded allogeneic adipose-derived mesenchymal stem cell (eASC) for the treatment of severe community-acquired bacterial pneumonia (CABP). MATERIALS AND METHODS: Randomized, multicenter, double-blind, placebo-controlled, phase 1b/2a trial. Patients with severe CABP were enrolled to receive intravenous infusions of Cx611 or placebo. The primary objective was safety including hypersensitivity reactions, thromboembolic events, and immunological responses to Cx611...
October 31, 2023: Journal of Critical Care
https://read.qxmd.com/read/37918130/estimated-glomerular-filtration-rate-among-intensive-care-unit-survivors-from-the-removal-of-race-coefficient-to-cystatin-c-based-equations
#24
JOURNAL ARTICLE
Alberto Pinsino, Jianwen Wu, Amira Mohamed, Alban Cela, Tsai-Chin Yu, Samuel J Rednor, Michelle Ng Gong, Ari Moskowitz
PURPOSE: Black race coefficient used in serum creatinine (sCr)-based estimated glomerular filtration rate (eGFR) calculation may perpetuate racial disparities. Among intensive care unit (ICU) survivors, sCr overestimates kidney function due to sarcopenia. Cystatin C (cysC) is a race- and muscle mass-independent eGFR marker. We investigated the impact of removing the race coefficient from sCr-based eGFR and compared cysC- and sCr-based eGFR in ICU survivors. MATERIALS AND METHODS: Among 30,920 patients from 2 institutions in the Bronx and Boston, eGFR was calculated at hospital discharge using sCr-based equations with and without race coefficient (eGFRsCr2009 and eGFRsCr2021 )...
October 30, 2023: Journal of Critical Care
https://read.qxmd.com/read/37890357/exploring-the-norepinephrine-to-angiotensin-ii-conversion-ratio-in-patients-with-vasodilatory-hypotension-a-post-hoc-analysis-of-the-aramis-trial
#25
JOURNAL ARTICLE
Emily J See, Anis Chaba, Sofia Spano, Akinori Maeda, Caroline Clapham, Jasmine Liu, Monique Khasin, Grace Liskaser, Glenn Eastwood, Rinaldo Bellomo
PURPOSE: Angiotensin II is approved for catecholamine-refractory vasodilatory shock but the conversion dose ratio from norepinephrine to angiotensin II remains unclear. METHODS: We conducted a post-hoc analysis of the Acute Renal effects of Angiotensin II Management in Shock (ARAMIS) trial involving patients with vasodilatory hypotension. We determined the norepinephrine equivalent dose immediately prior to angiotensin II initiation and calculated the conversion dose ratio between norepinephrine and angiotensin II...
October 25, 2023: Journal of Critical Care
https://read.qxmd.com/read/37890356/association-of-shock-index-with-echocardiographic-parameters-in-cardiac-intensive-care-unit
#26
JOURNAL ARTICLE
Meir Tabi, Mitchell Padkins, Barry Burstein, Anan Younis, Elad Asher, Courtney Bennett, Jacob C Jentzer
BACKGROUND: A high shock index (SI), the ratio of heart rate (HR) to systolic blood pressure (SBP), has been associated with unfavorable outcomes. We sought to determine the hemodynamic underpinnings of an elevated SI using 2-D and doppler Transthoracic Echocardiography (TTE) in unselected cardiac intensive care unit (CICU) patients. METHODS: We included Mayo Clinic CICU admissions from 2007 to 2018 who were in sinus rhythm at the time of TTE. The SI was calculated using HR and SBP at the time of TTE...
October 25, 2023: Journal of Critical Care
https://read.qxmd.com/read/37871403/clinical-features-etiologies-and-outcomes-of-central-nervous-system-infections-in-intensive-care-a-multicentric-retrospective-study-in-a-large-brazilian-metropolitan-area
#27
JOURNAL ARTICLE
Hugo Boechat Andrade, Ivan Rocha Ferreira da Silva, Rodolfo Espinoza, Marcel Treptow Ferreira, Mayara Secco Torres da Silva, Pedro Henrique Nascimento Theodoro, Paula João Tomás Detepo, Margareth Catoia Varela, Grazielle Viana Ramos, Aline Reis da Silva, Jesus Soares, Ermias D Belay, James J Sejvar, Fernando Augusto Bozza, José Cerbino-Neto, André Miguel Japiassú
PURPOSE: The goal of this study was to investigate severe central nervous system infections (CNSI) in adults admitted to the intensive care unit (ICU). We analyzed the clinical presentation, causes, and outcomes of these infections, while also identifying factors linked to higher in-hospital mortality rates. MATERIALS AND METHODS: We conducted a retrospective multicenter study in Rio de Janeiro, Brazil, from 2012 to 2019. Using a prediction tool, we selected ICU patients suspected of having CNSI and reviewed their medical records...
October 21, 2023: Journal of Critical Care
https://read.qxmd.com/read/37862956/lower-versus-higher-oxygen-targets-after-resuscitation-from-out-of-hospital-cardiac-arrest-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#28
REVIEW
Yi Xu, Fei Peng, Siying Wang, Hai Yu
PURPOSE: To update the existing evidence and gain further insight into effects of lower versus higher oxygen targets on the outcomes in patients resuscitated from out-of-hospital cardiac arrest (OHCA). METHODS: We performed a systematic review and meta-analysis of randomized controlled trials (RCTs) comparing lower versus higher oxygen targets on the outcomes among adults resuscitated from OHCA. The primary outcome was short-term survival (in hospital or within 30 days)...
October 18, 2023: Journal of Critical Care
https://read.qxmd.com/read/37862955/early-time-course-of-respiratory-mechanics-mechanical-power-and-gas-exchange-in-ards-patients
#29
JOURNAL ARTICLE
Tommaso Pozzi, Isabella Fratti, Emilia Tomarchio, Giovanni Bruno, Giulia Catozzi, Alessandro Monte, Davide Chiumello, Silvia Coppola
PURPOSE: To describe the clinical course of ARDS during the first three days of mechanical ventilation, to compare ventilatory setting, respiratory mechanics and gas exchange variables collected during the first three days of mechanical ventilation between patients who survived and died during intensive care unit (ICU) stay and to investigate the variables associated with mortality at ICU admission and throughout the first three days of mechanical ventilation. MATERIALS AND METHODS: Prospective observational study...
October 18, 2023: Journal of Critical Care
https://read.qxmd.com/read/37857068/passive-leg-raising-test-induced-changes-in-plethysmographic-variability-index-to-assess-fluid-responsiveness-in-critically-ill-mechanically-ventilated-patients-with-acute-circulatory-failure
#30
JOURNAL ARTICLE
Jihad Mallat, Malcolm Lemyze, Marc-Olivier Fischer
BACKGROUND: Passive leg raising (PLR) reliably predicts fluid responsiveness but requires a real-time cardiac index (CI) measurement or the presence of an invasive arterial line to achieve this effect. The plethysmographic variability index (PVI), an automatic measurement of the respiratory variation of the perfusion index, is non-invasive and continuously displayed on the pulse oximeter device. We tested whether PLR-induced changes in PVI (ΔPVIPLR ) could accurately predict fluid responsiveness in mechanically ventilated patients with acute circulatory failure...
October 17, 2023: Journal of Critical Care
https://read.qxmd.com/read/37832351/prevalence-of-life-sustaining-treatment-limitations-in-polish-very-old-intensive-care-patients-vips-a-post-hoc-analysis-of-two-prospective-observational-studies
#31
JOURNAL ARTICLE
Paweł Pasieka, Anna Surówka, Jakub Fronczek, Evan Skwara, Mirosław Czuczwar, Michał Borys, Paweł Krawczyk, Mirosław Ziętkiewicz, Łukasz R Nowak, Maciej Żukowski, Katarzyna Kotfis, Katarzyna Cwyl, Jacek Skowronek, Joanna Solek-Pastuszka, Jowita Biernawska, Paweł Grudzień, Paweł Nasiłowski, Natalia Popek, Waldemar Cyrankiewicz, Katarzyna Sierakowska, Wojciech Mudyna, Szymon Białka, Dorota Studzińska, Szymon Bernas, Mariusz Piechota, Waldemar Machała, Łukasz Sadowski, Jan Stefaniak, Radosław Owczuk, Małgorzata Szymkowiak, Ryszard Gawda, Natalia Kozera, Barbara Adamik, Waldemar Goździk, Agnieszka Wieczorek, Jarosław Janc, Anna Kluzik, Janusz Trzebicki, Paweł Zatorski, Wojciech Gola, Hubert Hymczak, Lukasz J Krzych, Szymon Czajka, Urszula Kościuczuk, Bartosz Kudliński, Hans Flaatten, Wojciech Szczeklik
PURPOSE: Several initiatives have recently focused on raising awareness about limitations of treatment in Poland. We aimed to assess if the propensity to limit LST among elderly patients in 2018-2019 increased compared to 2016-2017. METHODS: We analysed Polish cohorts from studies VIP1 (October 2016 - May 2017) and VIP2 (May 2018 - May 2019) that enrolled critical patients aged >80. We collected data on demographics, clinical features limitations of LST. Primary analysis assessed factors associated with prevalence of limitations of LST, A secondary analysis explored differences between patients with and without limitations of LST...
October 11, 2023: Journal of Critical Care
https://read.qxmd.com/read/37826998/is-the-flow-rate-the-missing-link-in-the-evolution-of-clinical-outcome-of-patients-using-high-flow-nasal-cannula
#32
LETTER
Adrián Gallardo, Paulina Vivanco Aravena, Muriel Ramírez-Santana, Patrick Sepúlveda Barisich
No abstract text is available yet for this article.
October 10, 2023: Journal of Critical Care
https://read.qxmd.com/read/37812993/comparison-of-various-surrogate-markers-for-venous-congestion-in-predicting-acute-kidney-injury-following-cardiac-surgery-a-cohort-study
#33
JOURNAL ARTICLE
Zhi-Tao Li, Da-Bing Huang, Jian-Feng Zhao, Hui Li, Shui-Qiao Fu, Wei Wang
BACKGROUND: Venous congestion has been demonstrated to increase the risk of acute kidney injury (AKI) after cardiac surgery. Although many surrogate markers for venous congestion are currently used in clinical settings, there is no consensus on which marker is most effective in predicting AKI. METHODS: We evaluated various markers of venous congestion, including central venous pressure (CVP), inferior vena cava (IVC) diameter, portal pulsatility fraction (PPF), hepatic vein flow pattern (HVF), intra-renal venous flow pattern (IRVF), and venous excess ultrasound grading score (VExUS) in adult patients undergoing cardiac surgery to compare their ability in predicting AKI...
October 7, 2023: Journal of Critical Care
https://read.qxmd.com/read/37797404/plasma-citrulline-concentration-and-plasma-lps-detection-among-critically-ill-patients-a-prospective-observational-study
#34
JOURNAL ARTICLE
Claire Chaignat, Laurent Lagrost, Karena Moretto, Jean-Paul Pais de Barros, Hadrien Winiszewski, Jacques Grober, Philippe Saas, Gaël Piton
PURPOSE: Gut can be a source of sepsis but sepsis itself can induce gut dysfunction. We aimed to study whether plasma citrulline, a marker of enterocyte mass, was correlated with plasma lipopolysaccharide, a potential marker of bacterial translocation among critically ill patients. MATERIALS AND METHODS: Critically ill patients admitted to the ICU. Plasma citrulline and plasma LPS concentration and activity were measured at ICU admission. Patients were compared according to the presence of sepsis at ICU admission...
October 3, 2023: Journal of Critical Care
https://read.qxmd.com/read/37797403/leaving-no-culture-undrawn-time-to-revisit-the-clabsi-and-cauti-metrics
#35
JOURNAL ARTICLE
Sarah E Nelson, Spyridoula Tsetsou, John Liang
Central line-associated bloodstream infections (CLABSIs) and catheter-associated urinary tract infections (CAUTIs) are quality metrics for many ICUs, and financial ramifications can be applied to hospitals and providers who perform poorly on these measures. Despite some perceived benefits to tracking these metrics, there are a range of issues associated with this practice: lack of a solid evidence base that documenting them has led to decreased infection rates, moral distress associated with identifying these infections, problems with their definitions, and others...
October 3, 2023: Journal of Critical Care
https://read.qxmd.com/read/37793244/consensus-based-indicators-for-evaluating-and-improving-the-quality-of-regional-collaborative-networks-of-intensive-care-units-results-of-a-nationwide-delphi-study
#36
JOURNAL ARTICLE
Gijs Hesselink, Rutger Verhage, Iwan C C van der Horst, Hans van der Hoeven, Marieke Zegers
PURPOSE: To select a consensus-based set of relevant and feasible indicators for monitoring and improving the quality of regional ICU network collaboratives. METHODS: A three-round Delphi study was conducted in the Netherlands between April and July 2022. A multidisciplinary expert panel prioritized potentially relevant and feasible indicators in two questionnaire rounds with two consensus meetings between both rounds. The RAND/UCLA appropriateness method was used to categorize indicators and synthesize results...
October 2, 2023: Journal of Critical Care
https://read.qxmd.com/read/37782978/extracorporeal-membrane-oxygenation-for-refractory-acute-eosinophilic-pneumonia
#37
LETTER
Pierre Bay, Matthieu Groh, Antoine Gaillet, Matthieu Schmidt, Charles-Edouard Luyt, Alain Combes, Marc Pineton de Chambrun
No abstract text is available yet for this article.
September 30, 2023: Journal of Critical Care
https://read.qxmd.com/read/37769422/the-human-gut-microbiome-in-critical-illness-disruptions-consequences-and-therapeutic-frontiers
#38
REVIEW
Jaeyun Sung, Sanu S Rajendraprasad, Kemuel L Philbrick, Brent A Bauer, Ognjen Gajic, Aditya Shah, Krzysztof Laudanski, Johan S Bakken, Joseph Skalski, Lioudmila V Karnatovskaia
With approximately 39 trillion cells and over 20 million genes, the human gut microbiome plays an integral role in both health and disease. Modern living has brought a widespread use of processed food and beverages, antimicrobial and immunomodulatory drugs, and invasive procedures, all of which profoundly disrupt the delicate homeostasis between the host and its microbiome. Of particular interest is the human gut microbiome, which is progressively being recognized as an important contributing factor in many aspects of critical illness, from predisposition to recovery...
September 26, 2023: Journal of Critical Care
https://read.qxmd.com/read/37769421/research-letter-clonidine-is-associated-with-faster-first-resolution-of-incident-icu-delirium-than-antipsychotics
#39
LETTER
Ting Ting Wu, Gillian Steiger, Louisa Smith, John W Devlin, Arjen J C Slooter
No abstract text is available yet for this article.
September 26, 2023: Journal of Critical Care
https://read.qxmd.com/read/37758553/neuropsychiatric-sequelae-following-extracorporeal-membrane-oxygenation-in-the-intensive-care-unit
#40
LETTER
Lara C A Pladet, Kim Luijken, Dirk W Donker, Olaf L Cremer, Christiaan L Meuwese
No abstract text is available yet for this article.
September 25, 2023: Journal of Critical Care
journal
journal
29363
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.