We have located links that may give you full text access.
Journal Article
Research Support, Non-U.S. Gov't
Review
Role of mass spectrometry-based proteomics in the study of cellular reprogramming and induced pluripotent stem cells.
Expert Review of Proteomics 2012 August
The generation of human induced pluripotent stem cells (iPSCs) from differentiated cells holds important clinical implications. Human iPSCs represent the most promising resource for regenerative medicine by enabling the use of patient-specific cells of any lineage without the need for embryonic material. However, before therapeutic applications using human iPSCs are carried out, extensive analyses are needed to assess molecular differences and similarities between human iPSCs and their natural counterparts, human embryonic stem cells. The pluralism of mechanisms acting in a biological system can be better approached by studying several elements simultaneously in an unbiased manner. This review will discuss recent genome-wide analyses of iPSCs (e.g., transcripts and epigenetics) and will introduce the huge potential of mass spectrometry-based proteomics in decoding the unique mechanisms underlying the reprogramming process and the molecular nature of cellular identity.
Full text links
Related Resources
Trending Papers
Review article: Recent advances in ascites and acute kidney injury management in cirrhosis.Alimentary Pharmacology & Therapeutics 2024 March 26
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app