keyword
https://read.qxmd.com/read/38680893/-melanella-martarum-sp-nov-gastropoda-eulimidae-the-first-parasitic-deep-sea-snail-reported-for-the-salas-gomez-ridge
#41
JOURNAL ARTICLE
Leonardo Santos de Souza, Cynthia M Asorey, Javier Sellanes
Eulimidae is a highly diverse family of gastropods that are often parasites of echinoderms. They are cosmopolitan and live from the intertidal to great depths. Despite its wide geographic and bathymetric distribution, no species of Eulimidae have been reported for the Salas & Gómez Ridge to date. In this study, we describe Melanella martarum sp. nov., which was collected during the EPIC oceanographic cruise onboard RV Mirai (JAMSTEC, Japan) in 2019. Seven specimens were collected with a modified Agassiz trawl on the summit of seamount "Pearl" (Zhemchuznaya) in the Salas & Gómez Ridge (25...
2024: PeerJ
https://read.qxmd.com/read/38680268/machine-learning-in-liver-surgery-benefits-and-pitfalls
#42
JOURNAL ARTICLE
Rafael Calleja, Manuel Durán, María Dolores Ayllón, Ruben Ciria, Javier Briceño
The application of machine learning (ML) algorithms in various fields of hepatology is an issue of interest. However, we must be cautious with the results. In this letter, based on a published ML prediction model for acute kidney injury after liver surgery, we discuss some limitations of ML models and how they may be addressed in the future. Although the future faces significant challenges, it also holds a great potential.
April 26, 2024: World Journal of Clinical Cases
https://read.qxmd.com/read/38679415/targeting-il-11-to-reduce-fibrocyte-circulation-and-lung-accumulation-in-animal-models-of-pulmonary-hypertension-associated-lung-fibrosis
#43
JOURNAL ARTICLE
Javier Milara, Inés Roger, Paula Montero, Enrique Artigues, Juan Escrivá, Raquel Del Río, Julio Cortijo
BACKGROUND AND PURPOSE: IL-11 is a member of the IL-6 family of cytokine initially considered as haematopoietic and cytoprotective factor. Recent evidence indicates that IL-11 promotes lung fibrosis and pulmonary hypertension in animal models and is elevated in lung tissue of patients with pulmonary fibrosis and pulmonary hypertension. Fibrocytes are bone marrow-derived circulating cells that participate in lung fibrosis and pulmonary hypertension, but the role of IL-11 on fibrocytes is unknown...
April 28, 2024: British Journal of Pharmacology
https://read.qxmd.com/read/38679409/mechanisms-underlying-memory-impairment-induced-by-fructose
#44
REVIEW
Javier Franco-Pérez
Fructose consumption has increased over the years, especially in adolescents living in urban areas. Growing evidence indicates that daily fructose consumption leads to some pathological conditions, including memory impairment. This review summarizes relevant data describing cognitive deficits after fructose intake and analyzes the underlying neurobiological mechanisms. Preclinical experiments show sex-related deficits in spatial memory; that is, while males exhibit significant imbalances in spatial processing, females seem unaffected by dietary supplementation with fructose...
April 26, 2024: Neuroscience
https://read.qxmd.com/read/38679032/why-latin-america-needs-a-regional-centre-for-disease-control-and-prevention
#45
JOURNAL ARTICLE
Patricia J Garcia, Jorge Saavedra, Laura Espinoza-Pajuelo, Fernando Ariel Garcia-Terron, Ximena Garzon, Adolfo Rubinstein, Enrique Paris, Martha Ospina, Milagros Guzmán-Acurio, Javier Guzmán
No abstract text is available yet for this article.
April 25, 2024: Lancet
https://read.qxmd.com/read/38678925/in-situ-acetylation-followed-by-liquid-liquid-extraction-and-gas-chromatography-mass-spectrometry-for-the-determination-of-bromophenols-in-urine
#46
JOURNAL ARTICLE
Javier Peña, Iria González-Mariño, José Luis Pérez Pavón
A novel and simple method combining in-situ acetylation, liquid-liquid extraction and gas chromatography-mass spectrometry (GC-MS) has been developed for the quantification of 10 bromophenols in urine, used as biomarkers of exposure to polybrominated diphenyl ethers. The analytical process involves an enzymatic hydrolysis of the bromophenol glucuronide fraction followed by an aqueous derivatization of the phenol group with acetic anhydride. A subsequent liquid-liquid extraction of the sample with hexane allows the injection of the organic layer, using a programmed temperature vaporizer, into a gas chromatograph coupled to a single quadrupole mass spectrometer...
April 24, 2024: Talanta
https://read.qxmd.com/read/38678645/atomistic-study-of-cocrcufeni-high-entropy-alloy-nanoparticles-role-of-chemical-complexity
#47
JOURNAL ARTICLE
Alice Vermale, Lilian Khelladi, Javier Rojas-Nunez, Samuel Baltazar, José Rogan, Max Ramirez, Fiorella Roco, Felipe J Valencia
High entropy alloy nanoparticles are envisaged as one of the most interesting materials compared to monoatomic materials due to their modulated properties in terms of their convenient surface-to-volume ratio. However, studies are still missing to unveil how composition or nanoparticle size can influence nanoparticle morphology. Based on molecular dynamics simulations, we perform a structural characterization as a function of nanoparticle size and the chemical composition of high entropy alloy nanoparticles subject to multiple annealing cycles...
April 19, 2024: Journal of Molecular Graphics & Modelling
https://read.qxmd.com/read/38677942/social-determinants-symptoms-and-mental-problems-in-adults-internally-displaced-by-armed-conflict-soacha-colombia-2019
#48
JOURNAL ARTICLE
Sandra Elizabeth Piñeros-Ortíz, Zulma Consuelo Urrego-Mendoza, Nathaly Garzón-Orjuela, Javier Eslava-Schmalbach
OBJECTIVE: To characterise social determinants of health, mental health problems and potentially problematic symptoms in the adult population displaced by internal armed conflict in Colombia. METHODS: Cross-sectional descriptive study with a random sample of 98 adults forcefully displaced to Soacha, Colombia, due to internal armed conflict. The Self Report Questionnaire to detect potentially problematic mental health problems and symptoms, and a structured questionnaire on social determinants of health were applied...
April 26, 2024: Revista Colombiana de psiquiatría (English ed.)
https://read.qxmd.com/read/38677598/men-of-mexican-ethnicity-alcohol-use-and-help-seeking-i-can-quit-on-my-own
#49
JOURNAL ARTICLE
Eden Hernandez Robles, Yessenia Castro, Sarah Najera, Juliana Cardoso, Rubi Gonzales, Jason Mallonee, Javier Segovia, Leslie Hinojosa-Salazar, Cecilia De Vargas, Craig Field
INTRODUCTION: Hispanics report higher rates of problematic alcohol use compared to non-Hispanic Whites while also reporting lower rates of alcohol treatment utilization compared to non-Hispanics. The study employs Anderson's Behavioral Model of Healthcare Utilization Model to guide the exploration of alcohol use, help-seeking and healthcare utilization. METHODS: The present qualitative study explored help-seeking and alcohol treatment utilization for Hispanic men of Mexican ethnicity...
April 25, 2024: J Subst Use Addict Treat
https://read.qxmd.com/read/38677463/evaluation-of-microplastic-pollution-using-bee-colonies-an-exploration-of-various-sampling-methodologies
#50
JOURNAL ARTICLE
Laura Cortes-Corrales, Jose Javier Flores, Adrian Rosa, Jozef J M Van der Steen, Flemming Vejsnæs, Ivo Roessink, Maria Jesús Martínez-Bueno, Amadeo R Fernández-Alba
Recent research has highlighted the potential of honeybees and bee products as biological samplers for monitoring xenobiotic pollutants. However, the effectiveness of these biological samplers in tracking microplastics (MPs) has not yet been explored. This study evaluates several methods of sampling MPs, using honeybees, pollen, and a novel in-hive passive sampler named the APITrap. The collected samples were characterized using a stereomicroscopy to count and categorise MPs by morphology, colour, and type...
April 25, 2024: Environmental Pollution
https://read.qxmd.com/read/38677182/targeting-il-6-trans-signalling-by-sgp130fc-attenuates-severity-in-sars-cov-2-infected-mice-and-reduces-endotheliopathy
#51
JOURNAL ARTICLE
María Ángeles Rodríguez-Hernández, Mercedes Baena-Bustos, David Carneros, Carola Zurita-Palomo, Pablo Muñoz-Pinillos, Jaime Millán, Francisco Javier Padillo, Cristian Smerdou, Cayetano von Kobbe, Stefan Rose-John, Matilde Bustos
BACKGROUND: SARS-CoV-2 infection is considered as a relapsing inflammatory process with a dysregulation of IL-6 signalling. Classic IL-6 signalling is thought to represent a defence mechanism against pathogens. In contrast, IL-6 trans-signalling has pro-inflammatory effects. In severe COVID-19, therapeutic strategies have focused on global inhibition of IL-6, with controversial results. We hypothesized that specific blockade of IL-6 trans-signalling could inhibit inflammatory response preserving the host defence activity inherent to IL-6 classic signalling...
April 26, 2024: EBioMedicine
https://read.qxmd.com/read/38676933/effects-of-pre-exercise-glycerol-supplementation-on-dehydration-metabolic-kinematic-and-thermographic-variables-in-international-race-walkers
#52
RANDOMIZED CONTROLLED TRIAL
Francisco Javier Martínez-Noguera, Alessio Cabizosu, Pedro E Alcaraz, Cristian Marín-Pagán
BACKGROUND: Due to the increase in global temperature, it is necessary to investigate solutions so that athletes competing in hot conditions can perform in optimal conditions avoiding loss of performance and health problems. Therefore, this study aims to evaluate the effect of pre-exercise glycerol supplementation during a rectangular test at ambient temperature mid (28.2ºC) on dehydration variables in international race walkers. METHODS: Eight international male race walkers (age: 28...
December 2024: Journal of the International Society of Sports Nutrition
https://read.qxmd.com/read/38676366/-not-available
#53
JOURNAL ARTICLE
Stephanie Van Asbroeck, Sebastian Köhler, Martin P J van Boxtel, Darren M Lipnicki, John D Crawford, Erico Castro-Costa, Maria Fernanda Lima-Costa, Sergio Luis Blay, Xiao Shifu, Tao Wang, Ling Yue, Richard B Lipton, Mindy J Katz, Carol A Derby, Maëlenn Guerchet, Pierre-Marie Preux, Pascal Mbelesso, Joanna Norton, Karen Ritchie, Ingmar Skoog, Jenna Najar, Therese Rydberg Sterner, Nikolaos Scarmeas, Mary Yannakoulia, Themis Dardiotis, Elena Rolandi, Annalisa Davin, Michele Rossi, Oye Gureje, Akin Ojagbemi, Toyin Bello, Ki Woong Kim, Ji Won Han, Dae Jong Oh, Stella Trompet, Jacobijn Gussekloo, Steffi G Riedel-Heller, Susanne Röhr, Alexander Pabst, Suzana Shahar, Nurul Fatin Malek Rivan, Devinder Kaur Ajit Singh, Erin Jacobsen, Mary Ganguli, Tiffany Hughes, Mary Haan, Allison E Aiello, Ding Ding, Qianhua Zhao, Zhenxu Xiao, Kenji Narazaki, Tao Chen, Sanmei Chen, Tze Pin Ng, Xinyi Gwee, Qi Gao, Henry Brodaty, Julian Trollor, Nicole Kochan, Antonio Lobo, Javier Santabárbara, Patricia Gracia-Garcia, Perminder S Sachdev, Kay Deckers
INTRODUCTION: The LIfestyle for BRAin Health (LIBRA) index yields a dementia risk score based on modifiable lifestyle factors and is validated in Western samples. We investigated whether the association between LIBRA scores and incident dementia is moderated by geographical location or sociodemographic characteristics. METHODS: We combined data from 21 prospective cohorts across six continents (N = 31,680) and conducted cohort-specific Cox proportional hazard regression analyses in a two-step individual participant data meta-analysis...
April 27, 2024: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
https://read.qxmd.com/read/38676263/a-g-m-i-d-based-low-power-lna-for-ka-band-applications
#54
JOURNAL ARTICLE
David Galante-Sempere, Jeffrey Torres-Clarke, Javier Del Pino, Sunil Lalchand Khemchandani
This article presents the design of a low-power low noise amplifier (LNA) implemented in 45 nm silicon-on-insulator (SOI) technology using the gm/ID methodology. The Ka-band LNA achieves a very low power consumption of only 1.98 mW andis the first time the gm/ID approach is applied at such a high frequency. The circuit is suitable for Ka-band applications with a central frequency of 28 GHz, as the circuit is intended to operate in the n257 frequency band defined by the 3GPP 5G new radio (NR) specification. The proposed cascode LNA uses the gm/ID methodology in an RF/MW scenario to exploit the advantages of moderate inversion region operation...
April 21, 2024: Sensors
https://read.qxmd.com/read/38676078/effect-of-rule-modifications-on-kinematic-parameters-using-maturity-stage-as-a-moderating-variable-in-u-10-football-players
#55
JOURNAL ARTICLE
Francisco Javier García-Angulo, José Manuel Palao, José María Giménez-Egido, Enrique Ortega-Toro
The aim of the present study was to analyse the effects of regulatory modifications in competitive situations on cinematic variables, considering maturity stage as a moderating factor, in youth football players. A quasi-experimental study was conducted in which 45 players with a mean age of 9.47 ± 0.54 participated. The independent variable analysed was the modification of rules (playing time, scoring, and specific rules). The dependent variables analysed were cinematic variables. These variables were recorded with WimuTM ...
April 11, 2024: Sensors
https://read.qxmd.com/read/38676073/prediction-of-degraded-infrastructure-conditions-for-railway-operation
#56
JOURNAL ARTICLE
Juan de Dios Sanz Bobi, Pablo Garrido Martínez-Llop, Pablo Rubio Marcos, Álvaro Solano Jiménez, Javier Gómez Fernández
In the railway sector, rolling stock and infrastructure must be maintained in perfect condition to ensure reliable and safe operation for passengers. Climate change is affecting the urban and regional infrastructure through sea level rise, water accumulations, river flooding, and other increased-frequency extreme natural situations (heavy rains or snows) which pose a challenge to maintenance. In this paper, the use of artificial intelligence based on predictive maintenance implementation is proposed for the early detection of degraded conditions of a bridge due to extreme climatic conditions...
April 11, 2024: Sensors
https://read.qxmd.com/read/38676044/a-comprehensive-review-of-behavior-change-techniques-in-wearables-and-iot-implications-for-health-and-well-being
#57
REVIEW
Carolina Del-Valle-Soto, Juan Carlos López-Pimentel, Javier Vázquez-Castillo, Juan Arturo Nolazco-Flores, Ramiro Velázquez, José Varela-Aldás, Paolo Visconti
This research paper delves into the effectiveness and impact of behavior change techniques fostered by information technologies, particularly wearables and Internet of Things (IoT) devices, within the realms of engineering and computer science. By conducting a comprehensive review of the relevant literature sourced from the Scopus database, this study aims to elucidate the mechanisms and strategies employed by these technologies to facilitate behavior change and their potential benefits to individuals and society...
April 10, 2024: Sensors
https://read.qxmd.com/read/38675182/comparative-cytotoxicity-of-menthol-and-eucalyptol-an-in-vitro-study-on-human-gingival-fibroblasts
#58
JOURNAL ARTICLE
Clara Puig-Herreros, José Luis Sanz, David García-Bernal, Francisco Javier Rodríguez-Lozano, Laura Murcia, Leopoldo Forner, James Ghilotti, Ricardo E Oñate-Sánchez, Sergio López-García
The aim of this study was to assess the influence of eucalyptol and menthol on the cell viability, migration, and reactive oxygen species production of human gingival fibroblasts (GFs) in vitro. Three different concentrations of eucalyptol and menthol were prepared following ISO 10993-5 guidelines (1, 5, and 10 mM). GFs were isolated from extracted teeth from healthy donors. The following parameters were assessed: cell viability via MTT, Annexin-V-FITC and 7-AAD staining, and IC50 assays; cell migration via horizontal scratch wound assay; and cell oxidative stress via reactive oxygen species assay...
April 9, 2024: Pharmaceutics
https://read.qxmd.com/read/38675156/fine-tuning-the-amphiphilic-properties-of-carbosilane-dendritic-networks-towards-high-swelling-thermogels
#59
JOURNAL ARTICLE
Silvia Muñoz-Sánchez, Andrea Barrios-Gumiel, Francisco Javier de la Mata, Sandra García-Gallego
Dendritic hydrogels based on carbosilane crosslinkers are promising drug delivery systems, as their amphiphilic nature improves the compatibility with poorly water-soluble drugs. In this work, we explored the impact of the complementary polymer on the amphiphilic properties of the dendritic network. Different polymers were selected as precursors, from the highly lipophilic propylene glycol (PPG) to the hydrophilic polyethylene glycol (PEG), including amphiphilic Pluronics L31, L35 and L61. The dithiol polymers reacted with carbosilane crosslinkers through UV-initiated thiol-ene coupling (TEC), and the resultant materials were classified as non-swelling networks (for PPG, PLUL31 and PLUL61 ) and high-swelling hydrogels (for PEG and PLUL35 )...
April 3, 2024: Pharmaceutics
https://read.qxmd.com/read/38675080/biodegradation-of-nitrile-gloves-as-sole-carbon-source-of-pseudomonas-aeruginosa-in-liquid-culture
#60
JOURNAL ARTICLE
Javier Alejandro Delgado-Nungaray, David Grajeda-Arias, Eire Reynaga-Delgado, Orfil Gonzalez-Reynoso
Nitrile gloves have become a significant environmental pollutant after the COVID-19 pandemic due to their single-use design. This study examines the capability of P. aeruginosa to use nitrile gloves as its sole carbon energy source. Biodegradation was determined by P. aeruginosa adapting to increasing nitrile glove concentrations at 1%, 3%, and 5% ( w / v ). The growth kinetics of P. aeruginosa were evaluated, as well as the polymer weight loss. Topographic changes on the glove surfaces were examined using SEM, and FT-IR was used to evaluate the biodegradation products of the nitrile gloves...
April 20, 2024: Polymers
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