Katja Pirc, Vesna Hodnik, Tina Snoj, Tea Lenarčič, Simon Caserman, Marjetka Podobnik, Hannah Böhm, Isabell Albert, Anita Kotar, Janez Plavec, Jure Borišek, Martina Damuzzo, Alessandra Magistrato, Boris Brus, Izidor Sosič, Stanislav Gobec, Thorsten Nürnberger, Gregor Anderluh
The lack of efficient methods to control the major diseases of crops most important to agriculture leads to huge economic losses and seriously threatens global food security. Many of the most important microbial plant pathogens, including bacteria, fungi, and oomycetes, secrete necrosis- and ethylene-inducing peptide 1 (Nep1)-like proteins (NLPs), which critically contribute to the virulence and spread of the disease. NLPs are cytotoxic to eudicot plants, as they disturb the plant plasma membrane by binding to specific plant membrane sphingolipid receptors...
April 15, 2021: PLoS Pathogens