Kristina Kostić, Jasmina Brborić, Giovanna Delogu, Milena R Simić, Stevan Samardžić, Zoran Maksimović, Maria Antonietta Dettori, Davide Fabbri, Jelena Kotur-Stevuljević, Luciano Saso
A comparative in vitro study of the antioxidant potential of natural phenols (zingerone, curcumin, raspberry ketone, magnolol) and their synthesized derivatives was performed. The antioxidant efficiency was evaluated in blood serum obtained from healthy individuals, by means of spectrophotometry, before and after the addition of pro-oxidant tert -butyl hydroperoxide (TBH). Moreover, the antioxidant effect of an equimolar mixture of curcumin and zingerone was investigated. Interpretation of our results reveals that in the blood serum of healthy individuals curcumin (C1), raspberry ketone (RK1), magnolol (M1) and synthesized derivative of zingerone (Z2) demonstrate remarkable antioxidant effects ( p < 0...
March 14, 2023: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry