Min Choon Tan, Fahimeh Talaei, Angkawipa Trongtorsak, Justin Z Lee, Pattara Rattanawong
BACKGROUND: The impact of chronic kidney disease (CKD) or end-stage renal disease (ESRD) on patients receiving transvenous lead extraction (TLE) is not well-established. OBJECTIVE: We performed a systematic review and meta-analysis to explore the association between CKD and all-cause mortality in TLE. METHODS: We searched the databases of PUBMED and EMBASE from inception to April 2022. Included studies were published TLE studies that compared the risk of mortality in CKD patients compared to control patients...
November 28, 2022: Pacing and Clinical Electrophysiology: PACE
(no author information available yet)
No abstract text is available yet for this article.
November 29, 2022: Circulation
Jignesh K Patel, Mathew S Maurer
No abstract text is available yet for this article.
November 29, 2022: Circulation
René Rissel, Sascha Koelm, Markus Schepers, Daniel-Sebastian Dohle, Joerg Albers, Mehmet Oezkur, Marc Kriege, Marc Bodenstein
The use of extracorporeal life support (ECLS) as part of cardio-circulatory support has increased rapidly in recent years. Severe hyperlactatemia is not uncommon in this group of patients. Lactate peak concentrations and lactate clearance have already been identified as independent marker for mortality in critical ill patients without mechanical device support. The aim of this study was to determine a supposed correlation between the variables lactate peak concentration and clearance in the blood and mortality in the ECLS context...
2022: PloS One
Suhee Chang, Diana Fulmer, Stella K Hur, Joanne L Thorvaldsen, Li Li, Yemin Lan, Eric A Rhon-Calderon, Nicolae Adrian Leu, Xiaowen Chen, Jonathan A Epstein, Marisa S Bartolomei
Dysregulation of the imprinted H19/IGF2 locus can lead to Silver-Russell syndrome (SRS) in humans. However, the mechanism of how abnormal H19/IGF2 expression contributes to various SRS phenotypes remains unclear, largely due to incomplete understanding of the developmental functions of these two genes. We previously generated a mouse model with humanized H19/IGF2 imprinting control region ( hIC1 ) on the paternal allele that exhibited H19/Igf2 dysregulation together with SRS-like growth restriction and perinatal lethality...
November 28, 2022: ELife
Jonathan P Piccini, Andrea M Russo, Parikshit S Sharma, Jordana Kron, Wendy Tzou, William Sauer, David S Park, Ulrika Birgersdotter-Green, David S Frankel, Jeff S Healey, John Hummel, Jacob Koruth, Dominik Linz, Suneet Mittal, Devi G Nair, Stanley Nattel, Peter A Noseworthy, Benjamin A Steinberg, Natalia A Trayanova, Elaine Y Wan, Erik Wissner, Emily P Zeitler, Paul J Wang
Despite the global COVID-19 pandemic, during the past 2 years, there have been numerous advances in our understanding of arrhythmia mechanisms and diagnosis and in new therapies. We increased our understanding of risk factors and mechanisms of atrial arrhythmias, the prediction of atrial arrhythmias, response to treatment, and outcomes using machine learning and artificial intelligence. There have been new technologies and techniques for atrial fibrillation ablation, including pulsed field ablation. There have been new randomized trials in atrial fibrillation ablation, giving insight about rhythm control, and long-term outcomes...
November 28, 2022: Circulation. Arrhythmia and Electrophysiology
Bode Ensam, Christopher C Cheung, Fahad Almehmadi, Bo Gregers Winkel, Chiara Scrocco, Paul Brennan, Kevin Leong, Alison Muir, Amanda Vanarva, Jacob Tfelt-Hansen, Jason D Roberts, Andrew D Krahn, Elijah R Behr
BACKGROUND: The implications of a drug-induced type 1 Brugada ECG pattern following sodium channel blocker provocation (SCBP) are not fully understood. METHODS: Baseline clinical and ECG data were obtained from consecutive unexplained cardiac arrest survivors undergoing SCBP at 3 centers. A further 15 SCBP positive (SCBP+) unexplained cardiac arrest survivors were recruited from 3 additional centers to explore ventricular fibrillation recurrence. RESULTS: A total of 121 consecutive unexplained cardiac arrest survivors underwent SCBP...
November 28, 2022: Circulation. Arrhythmia and Electrophysiology
Bruce S Stambler, Francis Plat, Philip T Sager, Silvia Shardonofsky, Douglas Wight, Diane Potvin, A Shekhar Pandey, James E Ip, Benoit Coutu, Blandine Mondésert, Laurence D Sterns, Matthew Bennett, Jeffrey L Anderson, Roger Damle, Ronald Haberman, A John Camm
BACKGROUND: Pharmacologic termination of paroxysmal supraventricular tachycardia (PSVT) often requires medically supervised intervention. Intranasal etripamil, is an investigational fast-acting, nondihydropyridine, L-type calcium channel blocker, designed for unsupervised self-administration to terminate atrioventricular nodal-dependent PSVT. Phase 2 results showed potential safety and efficacy of etripamil in 104 patients with PSVT. METHODS: NODE-301, a phase 3, multicenter, double-blind, placebo-controlled study evaluated the efficacy and safety of etripamil nasal spray administered, unsupervised in patients with symptomatic sustained PSVT...
November 28, 2022: Circulation. Arrhythmia and Electrophysiology
Maria Siemionow, Paulina Langa, Sonia Brodowska, Katarzyna Kozlowska, Kristina Zalants, Katarzyna Budzynska, Ahlke Heydemann
No abstract text is available yet for this article.
November 28, 2022: Stem cell reviews and reports
Masatoyo Nakajo, Yoshihisa Horizoe, Kodai Kawaji, Megumi Jinguji, Atsushi Tani, Yoshihiko Fukukura, Mitsuru Ohishi, Takashi Yoshiura
PURPOSE: This study examined the usefulness of the maximum standardized uptake value (SUVmax) of myocardial [123 I]-metaiodobenzylguanidine ([123 I]-MIBG) to characterize myocardial function by comparing it with echocardiographic parameters in patients with pheochromocytoma. MATERIALS AND METHODS: This study included 18 patients with pheochromocytoma who underwent both planar and [123 I]-MIBG single-photon emission computed tomography/computed tomography scans and echocardiography before surgery...
November 28, 2022: Japanese Journal of Radiology
Sven Knecht, Christian Sticherling
No abstract text is available yet for this article.
November 28, 2022: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
Robert C Ward, Christopher V DeSimone
No abstract text is available yet for this article.
November 28, 2022: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
Hagai D Yavin, Koji Higuchi, Arwa Younis, Elad Anter
BACKGROUND: A compressible lattice-tip catheter designed for focal ablation using radiofrequency or pulsed-field energies has been recently described. The objective of this study is to describe a new lattice catheter designed for single-shot pulmonary vein isolation (PVI). METHODS: This 8F catheter consists of a compressible lattice tip that is delivered over the wire and is expandable up to 34 mm (SpherePVI™, Affera Inc.). Pulsed field ablation (PFA) was applied from 6 elements using a biphasic waveform of microsecond scale (± 1...
November 28, 2022: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
Muhammad Furqan, Sanchit Chawla, Muhammad Majid, Samia Mazumdar, Gauranga Mahalwar, Evan Harmon, Allan Klein
PURPOSE OF REVIEW: To review myocarditis and pericarditis developing after COVID-19 vaccinations and identify the management strategies. RECENT FINDINGS: COVID-19 mRNA vaccines are safe and effective. Systemic side effects of the vaccines are usually mild and transient. The incidence of acute myocarditis/pericarditis following COVID-19 vaccination is extremely low and ranges 2-20 per 100,000. The absolute number of myocarditis events is 1-10 per million after COVID-19 vaccination as compared to 40 per million after a COVID-19 infection...
November 28, 2022: Current Cardiology Reports
Giorgio Faganello, Linda Pagura, Dario Collia, Giulia Barbati, Alessia Paldino, Matteo Dal Ferro, Elisa Croatto, Gianfranco Sinagra, Gianni Pedrizzetti, Andrea Di Lenarda
Left ventricular ejection function (LVEF) is not reliable in identifying subtle systolic dysfunction. Speckle Tracking (ST) plays a promising role and hemodynamic forces (HDFs) are emerging as marker of LV function. The role of LV myocardial deformation and HDFs was investigated in a cohort of patients with aortic stenosis (AS) and normal LVEF. Two hundred fifty three patients (median age 79 years, IQR 73 - 83 years) with mild (n = 87), moderate (n =77) and severe AS (n =89) were retrospectively enrolled. 2D echocardiographic global longitudinal strain (GLS), circumferential strain (GCS) and HDFs were determined...
November 28, 2022: International Journal of Cardiovascular Imaging
H Elhedai, G S Arul, S Yong, P Nagakumar, H K Kanthimathinathan, I Jester, M Chaudhari, T J Jones, O Stumper, A N Seale
INTRODUCTION: Exomphalos is an anterior abdominal wall defect resulting in herniation of contents into the umbilical cord. Severe associated chromosomal anomalies and congenital heart disease (CHD) are known to influence mortality, but it is not clear which cardiac anomalies have the greatest impact on survival. METHODS: We performed a retrospective review of the treatment and outcome of patients with exomphalos over a 30-year period (1990-2020), with a focus on those with the combination of exomphalos major and major CHD (EMCHD)...
November 28, 2022: Pediatric Surgery International
Kisaki Amemiya, Yumiko Yonemoto, Hatsue Ishibashi-Ueda, Manabu Matsumoto, Keiko Ohta-Ogo, Yoshihiko Ikeda, Junjiro Kobayashi, Satsuki Fukushima, Tomoyuki Fujita, Kinta Hatakeyama
Systemic and cerebral embolisms are serious complications of associated with cardiac myxoma. Embolism risk reportedly depends on the gross and histological morphology. This study is aimed at analyzing the morphologic pattern of excised cardiac myxoma as a high-risk embolic cause. Between 1978 and April 2022, 116 surgical specimens of cardiac myxomas were recorded at the pathology department of our hospital. The tumors were classified into three types based on their macroscopic shapes and external morphology-round-smooth, irregular, and villous-to investigate the embolic complications...
November 28, 2022: Virchows Archiv: An International Journal of Pathology
Kyohei Usami, Hiroaki Watabe, Tomoya Hoshi, Shunsuke Sakai, Daigo Hiraya, Akira Sato, Masaki Ieda
OBJECTIVES: To investigate the relationship between periprocedural myocardial injury (PMI) and plaque characteristics detected by multidetector computed tomography (MDCT) and cardiac magnetic resonance imaging (CMR). MATERIALS AND METHODS: This observational retrospective study, between July 2012 and October 2019, included chronic coronary syndrome patients undergoing elective percutaneous coronary intervention (PCI) after MDCT and CMR. High-intensity plaque (HIP) on non-contrast T1-weighted imaging was defined as a coronary plaque-to-myocardium signal intensity ratio of ≥ 1...
November 28, 2022: European Radiology
Takashi Ohkura, Takashi Yamasaki, Ken Kakita, Tetsuhisa Hattori, Tetsuro Nishimura, Hibiki Iwakoshi, Satoshi Shimoo, Hirokazu Shiraishi, Satoaki Matoba, Keitaro Senoo
Balloon ablation therapy has recently been used for atrial fibrillation (AF) ablation. Laser balloons possess the property in which the balloon size can be changed. Standard laser balloon ablation (Standard LBA) was followed by additional ablation using a maximally extended balloon (Extended LBA) and its lesion characteristics were compared to cryoballoon ablation (CBA), another balloon technology. From June 2020 to July 2021, patients with paroxysmal AF who underwent an initial pulmonary vein (PV) isolation were enrolled...
November 28, 2022: Heart and Vessels
Hilke Könemann, Gerrit Frommeyer, Katja Zeppenfeld, Lars Eckardt
The recently published guidelines of the European Society of Cardiology (ESC) on the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death is an update of the 2015 guideline. For the first time a new section is dedicated to public basic life support. In the acute treatment of ventricular arrhythmias electrical cardioversion is upgraded, and there is a new focus on the management of electrical storm. Recommendations for the comprehensive diagnostic evaluation of patients with first manifestations of ventricular arrhythmias structured according to common clinical scenarios are also new...
November 28, 2022: Herz
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