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https://read.qxmd.com/read/36966429/fetal-nt-probnp-levels-and-their-course-in-severe-anemia-during-intrauterine-treatment
#1
JOURNAL ARTICLE
Pauline Siebers, Ulrich Gembruch, Waltraut Maria Merz, Florian Recker, Andreas Müller, Brigitte Strizek, Annegret Geipel, Christoph Berg, Eva Christin Weber
PURPOSE: In adults and fetuses, N-terminal pro-B-type natriuretic peptide (NT-proBNP) is a marker of cardiac failure and myocardial remodelling. We examined the effect of anemia and intrauterine transfusion (IUT) on NT-proBNP concentrations in fetuses with anemia and established gestational age-dependent reference values of a control group. METHODS: We analyzed NT-proBNP levels in anemic fetuses that underwent serial intrauterine transfusions (IUT), focusing on different causes and severity of anemia and comparing the results to a non-anemic control group...
March 26, 2023: Archives of Gynecology and Obstetrics
https://read.qxmd.com/read/36966408/-pediatric-cardiopulmonary-resuscitation
#2
JOURNAL ARTICLE
Gyula Tövisházi, Katalin Csordás, Balázs Hauser
Our aim is to summarize the new European Resuscitation Council (ERC) 2021 guidelines on paediatric life support. In children, exhaustion of compensatory mechanisms in respiratory or circulatory failure leads to cardiac arrest. Recognition and treatment of children in critical condition are the most important element of its prevention. With the ABCDE approach, life-threatening problems can be identified and treated using simple interventions (bag-mask ventilation, intraosseous access, fluid bolus, etc.). Important new recommendations: 4-hand ventilation during bag-mask ventilation, target saturation of 94-98% during oxygen therapy, and fluid bolus of 10 ml/kg...
March 26, 2023: Orvosi Hetilap
https://read.qxmd.com/read/36966407/-in-hospital-cardiac-arrest-and-basic-life-support
#3
JOURNAL ARTICLE
Domonkos Kiss, Gábor Fritúz, Enikő Kovács, Csaba Diószeghy
Survival of in-hospital cardiac arrests is still as low as 15-35%. Healthcare workers should closely monitor patients' vital signs, notice any deterioration, and initiate the necessary actions to prevent cardiac arrest. The introduction of early warning sign protocols (including the monitoring of respiratory rate, oxygen saturation, pulse, blood pressure, consciousness, etc.) can improve the recognition of periarrest patients during hospital stay. However, when a cardiac arrest occurs, healthcare workers should also be able to work in team and follow the relevant protocols delivering good quality chest compressions and early defibrillation...
March 26, 2023: Orvosi Hetilap
https://read.qxmd.com/read/36966406/-out-of-hospital-adult-basic-life-support-new-guidelines-and-the-involvement-of-bystanders
#4
JOURNAL ARTICLE
Noémi Molnár, Ferenc Nagy, Gábor Fritúz, Enikő Kovács, Csaba Diószeghy
Survival rate for out-of-hospital cardiac arrest remains low across Europe. In the last decade, involving bystanders turned out to be one of the most important key factors in improving the outcome of out-of-hospital cardiac arrest. Beside recognizing cardiac arrest and initiate chest compressions, bystanders could be also involved in delivering early defibrillation. Although adult basic life support is a sequence of simple interventions that can be easily learnt even by schoolchildren, non-technical skills and emotional components can complicate real-life situations...
March 26, 2023: Orvosi Hetilap
https://read.qxmd.com/read/36966405/-the-novelties-of-adult-advanced-life-support-and-post-resuscitation-therapy
#5
JOURNAL ARTICLE
Noémi Szabó Némedi, Gerda Lóczi, Enikő Kovács, Endre Zima
The fourth element of chain-of-survival contains advanced life support and post-resuscitation treatment. Both treatment options influence the outcome of patients suffering cardiac arrest. Advanced life support includes all interventions that require special medical equipment and expertise. High-quality chest compressions and early defibrillation (if indicated) compose the main elements of advanced life support. Clarifying and treating the cause of cardiac arrest have also high priority, in which point-of-care ultrasound plays an important role...
March 26, 2023: Orvosi Hetilap
https://read.qxmd.com/read/36966404/-the-role-of-extracorporeal-life-support-in-cardiopulmonary-resuscitation
#6
JOURNAL ARTICLE
Enikő Kovács, Endre Németh, Jutas Prigya, Petra Szvath, István Édes, István Hartyánszky, Ádám Soltész, Gergely Richárd Csikós, Levente Fazekas, János Gál, Dávid Becker, Béla Merkely, Endre Zima
The frequency of the administration of extracorporeal cardiopulmonary resuscitation is increasing both in the treatment of in-hospital and out-of-hospital cardiac arrest. The latest resuscitation guidelines support the use of mechanical circulatory support devices in the cases of prolonged cardiopulmonary resuscitation in certain selected patient groups. However, only little evidence is available regarding the effectiveness of extracorporeal cardiopulmonary resuscitation, and many open questions remained unanswered regarding the adequate conditions of this modality...
April 2, 2023: Orvosi Hetilap
https://read.qxmd.com/read/36966402/-rhythm-and-rate-control-in-the-context-of-resuscitation-and-periarrest-states
#7
JOURNAL ARTICLE
Dénes Kiss, Ádám Pál-Jakab, Boldizsár Kiss, Dávid Pilecky, Endre Zima
Cardiovascular mortality has declined significantly in recent years, however, sudden cardiac death remains the leading cause of death in a range of different mortality indicators, very often caused by cardiac arrhythmias. The electrophysiological causes of sudden cardiac death include ventricular tachycardia, ventricular fibrillation, asystole and pulseless electrical activity. In addition, other cardiac arrhythmias may also trigger sudden cardiac death, periarrest arrhytmias. The rapid and accurate recognition of the various arrhythmias and their appropriate management are major challenges at both prehospital and hospital care levels...
April 2, 2023: Orvosi Hetilap
https://read.qxmd.com/read/36966401/-impact-of-the-covid-19-pandemic-on-basic-resuscitation-and-success-rate-after-sudden-cardiac-arrest
#8
JOURNAL ARTICLE
Bettina Nagy, Boldizsár Kiss, Alexandra Fekete-Győr, Ádám Pál-Jakab, Enikő Kovács, Endre Zima
Since the onset of the coronavirus disease, infection-related mortality has been tracked worldwide and the number of deaths caused by the virus is counted daily. The coronavirus pandemic has not only transformed our daily life, but reorganized the whole healthcare system. In response to the increased demand for hospital admissions, leaders in different countries have implemented a number of emergency actions. The restructuring has had both direct and indirect negative effects on the epidemiology of sudden cardiac death, the willingness of lay rescuer to give cardiopulmonary resuscitation and the use of automated external defibrillators, but these negative effects vary widely across continents and countries...
April 2, 2023: Orvosi Hetilap
https://read.qxmd.com/read/36966400/-cardiopulmonary-resuscitation-in-special-circumstances
#9
JOURNAL ARTICLE
Petra Szvath, Eszter Tamáska, Bettina Nagy, Béla Merkely, János Gál, Endre Zima, Enikő Kovács
The standard process of basic and advanced life support can be complicated by a number of special circumstances. Over the last decade, the European Resuscitation Council developed an increasingly detailed guideline regarding the diagnosis and therapy of these situations. In our short review, we summarize the most important recommendations for the management of cardiopulmonary resuscitation in special circumstances. The proper training in non-technical skills and teamwork is crucial in the management of these situations...
April 2, 2023: Orvosi Hetilap
https://read.qxmd.com/read/36966399/-the-treatment-of-traumatic-cardiac-arrest
#10
JOURNAL ARTICLE
Tamás Kassai, Krisztina Baranyi
The pathophysiology, formation and course of traumatic cardiac arrest differs from other types of circulatory arrests, leading to some specific considerations regarding cardiopulmonary resuscitation in this condition. The treatment of reversible causes takes a higher priority than initiating chest compressions. The success of the management and treatment of patients suffering traumatic cardiac arrest depends on early timing and a well-organized chain of survival, including not only advanced prehospital care, but also further therapy in special trauma centers...
April 2, 2023: Orvosi Hetilap
https://read.qxmd.com/read/36966325/luteolin-intake-is-negatively-associated-with-all-cause-and-cardiac-mortality-among-patients-with-type-2-diabetes-mellitus
#11
JOURNAL ARTICLE
Wenbin Zhang, Duanbin Li, Yu Shan, Yecheng Tao, Qingqing Chen, Tianli Hu, Menghan Gao, Zhezhe Chen, Hangpan Jiang, Changqin Du, Min Wang, Kai Guo
BACKGROUND: Luteolin, a common flavonoid in our daily diet, has potent anti-diabetic effects. However, its prognostic impact on type 2 diabetes mellitus (T2DM) is still uncertain. This study aimed to clarify this association. METHODS: In this prospective cohort study, 2,461 patients with T2DM were included from the National Health and Nutrition Examination Survey. Dietary luteolin intake was estimated by the type and amount of food consumed in a 24-hour dietary recall...
March 25, 2023: Diabetology & Metabolic Syndrome
https://read.qxmd.com/read/36966309/sub-clinical-rheumatic-heart-disease-rhd-detected-by-hand-held-echocardiogram-in-children-participating-in-a-school-based-rhd-prevention-program-in-tanzania
#12
JOURNAL ARTICLE
Pilly Chillo, Reuben Mutagaywa, Deogratias Nkya, Marina Njelekela, Gideon Kwesigabo, Febronia Kahabuka, Vanessa Kerry, Appolinary Kamuhabwa
BACKGROUND: Rheumatic Heart Disease (RHD) continues to cause suffering and premature deaths in many sub-Saharan Africa (SSA) countries, where the disease is still endemic. RHD is largely preventable and determining its community burden is an important critical step in any RHD prevention program. METHODS: We conducted a cross-sectional study of 5-16 years old pupils from 11 primary schools participating in an RHD prevention program in 4 districts in Tanzania, between 2018 and 2019...
March 25, 2023: BMC Cardiovascular Disorders
https://read.qxmd.com/read/36966120/reducing-the-risk-of-spinal-cord-injury-in-patients-with-asymptomatic-cervical-stenosis-undergoing-cardiac-and-vascular-surgery
#13
JOURNAL ARTICLE
Justin Mitchell, Nada Abdelhakim, Paul Nagib, Andrew J Grossbach, Eric Bourekas, Sujatha Bhandary, Greg Bigelow, Hamdy Awad
No abstract text is available yet for this article.
March 1, 2023: Journal of Cardiothoracic and Vascular Anesthesia
https://read.qxmd.com/read/36966040/state-of-the-art-paper-cardiac-computed-tomography-of-the-left-atrium-in-atrial-fibrillation
#14
REVIEW
Neil Bodagh, Michelle C Williams, Keeran Vickneson, Ali Gharaviri, Steven Niederer, Steven E Williams
The clinical spectrum of atrial fibrillation means that a patient-individualised approach is required to ensure optimal treatment. Cardiac computed tomography can accurately delineate atrial structure and function and could contribute to a personalised care pathway for atrial fibrillation patients. The imaging modality offers excellent spatial resolution and has been utilised in pre-, peri- and post-procedural care for patients with atrial fibrillation. Advances in temporal resolution, acquisition times and analysis techniques suggest potential expanding roles for cardiac computed tomography in the future management of patients with atrial fibrillation...
March 23, 2023: Journal of Cardiovascular Computed Tomography
https://read.qxmd.com/read/36965754/cardiac-surgery-in-variable-resource-contexts-overly-ambitious-or-long-overdue
#15
EDITORIAL
Dominique Vervoort, Kathleen N Fenton
No abstract text is available yet for this article.
March 23, 2023: Annals of Thoracic Surgery
https://read.qxmd.com/read/36965743/linagliptin-exacerbates-heart-failure-due-to-energy-deficiency-via-downregulation-of-glucose-utilization-and-absorption-in-a-mouse-model
#16
JOURNAL ARTICLE
Aya Shiraki, Jun-Ichi Oyama, Takahiko Shimizu, Koichi Node
Use of dipeptidyl peptidase-4 (DPP4) inhibitor in some clinical trials might have caused heart failure (HF), leading to increased hospitalizations. The aim of the present study was to determine whether linagliptin has any effect on chronic dilated HF, and its underlying mechanisms. Physiologic and pathologic studies were conducted on heart/muscle-specific manganese superoxide dismutase-deficient mice, which exhibited dilated cardiomyopathy, and were randomized to receive a low dose (1 mg/kg, HF-L group) or high dose (10 mg/kg, HF-H group) mixed with food, or normal food (HF group), for 8 weeks...
March 23, 2023: European Journal of Pharmacology
https://read.qxmd.com/read/36965701/direct-cardiac-reprogramming-a-new-technology-for-cardiac-repair
#17
REVIEW
Paige E Brlecic, Clark A Bonham, Todd K Rosengart, Megumi Mathison
Cardiovascular disease is one of the leading causes of morbidity and mortality worldwide, with myocardial infarctions being amongst the deadliest manifestations. Reduced blood flow to the heart can result in the death of cardiac tissue, leaving affected patients susceptible to further complications and recurrent disease. Further, contemporary management typically involves a pharmacopeia to manage the metabolic conditions contributing to atherosclerotic and hypertensive heart disease, rather than regeneration of the damaged myocardium...
March 23, 2023: Journal of Molecular and Cellular Cardiology
https://read.qxmd.com/read/36965700/optogenetic-termination-of-atrial-tachyarrhythmias-by-brief-pulsed-light-stimulation
#18
JOURNAL ARTICLE
Motoki Nakao, Masaya Watanabe, Lucile Miquerol, Hiroyuki Natsui, Takuya Koizumi, Takahide Kadosaka, Taro Koya, Hikaru Hagiwara, Rui Kamada, Taro Temma, Antoine A F de Vries, Toshihisa Anzai
AIMS: The most efficient way to acutely restore sinus rhythm from atrial fibrillation (AF) is electrical cardioversion, which is painful without adequate sedation. Recent studies in various experimental models have indicated that optogenetic termination of AF using light-gated ion channels may provide a myocardium-specific and potentially painless alternative future therapy. However, its underlying mechanism(s) remain(s) incompletely understood. As brief pulsed light stimulation, even without global illumination, can achieve optogenetic AF termination, besides direct conduction block also modulation of action potential (AP) properties may be involved in the termination mechanism...
March 23, 2023: Journal of Molecular and Cellular Cardiology
https://read.qxmd.com/read/36965699/cellular-reprogramming-of-fibroblasts-in-heart-regeneration
#19
REVIEW
Congwu Chi, Kunhua Song
Myocardial infarction causes the loss of cardiomyocytes and the formation of cardiac fibrosis due to the activation of cardiac fibroblasts, leading to cardiac dysfunction and heart failure. Unfortunately, current therapeutic interventions can only slow the disease progression. Furthermore, they cannot fully restore cardiac function, likely because the adult human heart lacks sufficient capacity to regenerate cardiomyocytes. Therefore, intensive efforts have focused on developing therapeutics to regenerate the damaged heart...
March 23, 2023: Journal of Molecular and Cellular Cardiology
https://read.qxmd.com/read/36965688/is-it-time-to-personalize-digital-health-interventions
#20
EDITORIAL
Lama Ghazi, Adam D DeVore
No abstract text is available yet for this article.
March 23, 2023: Journal of Cardiac Failure
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