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Pain Medicine

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https://read.qxmd.com/read/31298289/perineural-platelet-rich-plasma-for-diabetic-neuropathic-pain-could-it-make-a-difference
#1
Manal Hassanien, Abdelraheem Elawamy, Emad Zarief Kamel, Walaa A Khalifa, Ghada Mohamed Abolfadl, Al Shimaa Ismael Roushdy, Randa A El Zohne, Yasmine S Makarem
OBJECTIVE: To evaluate the clinical effect of perineural platelet-rich plasma (PRP) injection for pain and numbness alleviation in diabetic peripheral neuropathy (DPN). STUDY DESIGN: A randomized prospective clinical trial. SETTING: Pain clinic and Rheumatology and Rehabilitation Departments, Assiut University Hospital. METHODS: Sixty adult patients with type II DM accompanied by DPN of at least six months' duration were assessed by modified Toronto Clinical Neuropathy Score (mTCNS) and randomly allocated into two groups...
July 12, 2019: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://read.qxmd.com/read/31282958/mechanisms-of-action-by-which-local-anesthetics-reduce-cancer-recurrence-a-systematic-review
#2
Ravi K Grandhi, Barbara Perona
BACKGROUND: Surgery in concert with anesthesia is a key part of the management of advanced-stage cancers. Anesthetic agents such as opioids and volatile anesthetics have been shown to promote recurrence in preclinical models, whereas some animal models have shown that the use of lidocaine may be beneficial in reducing cancer recurrence. The purpose of this article is to review the current literature to highlight the mechanisms of action by which local anesthetics are thought to reduce cancer recurrence...
July 8, 2019: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://read.qxmd.com/read/31274168/the-use-of-l2-and-l3-lumbar-sympathetic-blockade-for-cancer-related-pain-an-experience-and-recommendation-in-the-oncologic-population
#3
Matthew A Spiegel, Lee Hingula, Grant H Chen, Aron Legler, Vinay Puttanniah, Amitabh Gulati
OBJECTIVE: The sympathetic nervous system has a recognized role in transmission of pain, and the lumbar sympathetic blockade is intended to provide analgesia. We share our experiences of lumbar sympathetic blockade in the treatment of cancer-related pain. METHODS: We performed a retrospective analysis of patients with cancer-related pain in the back, abdomen, pelvis, or legs treated at Memorial Sloan Kettering Cancer Center between 2000 and 2018 undergoing lumbar sympathetic blockade at L2 or L3...
July 5, 2019: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://read.qxmd.com/read/31271434/exploring-the-meaning-of-cognitive-behavioral-therapy-for-insomnia-for-patients-with-chronic-pain
#4
Erin Koffel, Erin Amundson, Jennifer P Wisdom
OBJECTIVE: Insomnia is one of the most common, persistent, and distressing symptoms associated with chronic pain. Cognitive behavioral therapy for insomnia (CBT-I) is the firstline treatment for insomnia, but patient preferences and perspectives about CBT-I within the context of chronic pain are unknown. The current qualitative study sought to understand the experience of CBT-I among patients with chronic pain, including aspects of CBT-I that were found to be difficult (e.g., pain as a specific barrier to adherence/dropout), changes in sleep and pain functioning after CBT-I, and aspects of CBT-I that were appreciated...
July 4, 2019: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://read.qxmd.com/read/31268147/investigating-the-feasibility-of-a-modified-quantitative-sensory-testing-approach-to-profile-sensory-function-and-predict-pain-outcomes-following-intrathecal-baclofen-implant-surgery-in-cerebral-palsy
#5
Chantel C Barney, Alyssa M Merbler, Donald A Simone, David Walk, Frank J Symons
OBJECTIVES: Intrathecal baclofen (ITB) pumps used to manage spasticity in children with cerebral palsy (CP) also improve pain outcomes for some but not all patients. The purpose of this clinical feasibility study was to explore whether a quantitative sensory testing approach could a) be modified and used to subgroup individuals into sensory profiles and b) test whether the profiles were related to postimplant pain outcomes (i.e., pain responsive or pain persistent). SUBJECTS: A purposeful clinical sample of nine children with CP (mean age = 12...
July 3, 2019: Pain Medicine
https://read.qxmd.com/read/31260077/teaching-cases-to-promote-clinical-advancement-in-pain-medicine
#6
Jianguo Cheng, R Norman Harden, Rollin M Gallagher
No abstract text is available yet for this article.
July 1, 2019: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://read.qxmd.com/read/31260064/anatomic-considerations-for-injection-of-the-lateral-atlanto-axial-joint
#7
Charis McNabney, Anesh Chavda, Hatim Alabsi, Stephanie L Sellers, Darra T Murphy, David Fenton
OBJECTIVE: We aimed to define the potential complications of intra-articular steroid injections into the lateral C1-2 articulations and safety margins to the relevant structures. METHODS: A total of 488 contrast-enhanced computed tomography angiogram (CTA) "arch to vertex" studies were retrospectively reviewed for theoretical intersection of the vertebral artery or thecal sac and distance of the named structures from the anticipated/theoretical trajectory of injection into the lateral C1-C2 joint...
July 1, 2019: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://read.qxmd.com/read/31241135/the-effect-of-stress-on-repeated-painful-stimuli-with-and-without-painful-conditioning
#8
Morten Hoegh, Jeppe N Poulsen, Laura Petrini, Thomas Graven-Nielsen
OBJECTIVES: Stress and pain have been interrelated in clinical widespread pain conditions. Studies indicate that acute experimental stress in healthy volunteers has a negative effect on the descending inhibitory pain control system and thus the ability to inhibit one painful stimulus with another (conditioned pain modulation [CPM]) although without effect on general pain sensitivity. CPM effects can be assessed immediately after the stress induction, whereas some physiological stress responses (e...
June 26, 2019: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://read.qxmd.com/read/31237610/self-administered-acupressure-for-chronic-low-back-pain-a-randomized-controlled-pilot-trial
#9
Susan Lynn Murphy, Richard Edmund Harris, Nahid Roonizi Keshavarzi, Suzanna Maria Zick
OBJECTIVE: Chronic low back pain (CLBP) is associated with fatigue, pain, poor sleep, and disability. Acupressure is a low-risk treatment option used to manage symptoms in other groups, but its efficacy, particularly on fatigue and sleep, is unknown in CLBP. This study examined preliminary effects of two types of self-administered acupressure (relaxing and stimulating) on fatigue, pain, sleep, and reported disability. METHODS: A randomized pilot trial was conducted (N = 67) in which participants were randomized into six weeks of relaxing acupressure, stimulating acupressure, or usual care...
June 25, 2019: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://read.qxmd.com/read/31216028/pinprick-evoked-potentials-reliable-acquisition-in-healthy-human-volunteers
#10
Jan Rosner, Paulina Simonne Scheuren, Stephanie Anja Stalder, Armin Curt, Michèle Hubli
OBJECTIVE: Pinprick evoked potentials (PEPs) represent a novel tool to assess the functional integrity of mechano-nociceptive pathways with a potential toward objectifying sensory deficits and gain seen in neurological disorders. The aim of the present study was to evaluate the feasibility and reliability of PEPs with respect to age, stimulation site, and skin type. METHODS: Electroencephalographic responses evoked by two pinprick stimulation intensities (128 mN and 256 mN) applied at three sites (hand dorsum, palmar digit II, and foot dorsum) were recorded in 30 healthy individuals...
June 19, 2019: Pain Medicine
https://read.qxmd.com/read/31216021/news-media-recommendations-for-opioid-disposal-keeping-flush-with-the-guidelines
#11
Benjamin J Oldfield, William C Becker
No abstract text is available yet for this article.
June 19, 2019: Pain Medicine
https://read.qxmd.com/read/31211385/assessing-endogenous-pain-inhibition-test-retest-reliability-of-exercise-induced-hypoalgesia-in-local-and-remote-body-parts-after-aerobic-cycling
#12
Stefan Gomolka, Henrik Bjarke Vaegter, Jo Nijs, Mira Meeus, Hannah Gajsar, Monika I Hasenbring, Christina Titze
OBJECTIVE: Acute exercise can trigger a hypoalgesic response (exercise-induced hypoalgesia [EIH]) in healthy subjects. Despite promising application possibilities of EIH in the clinical context, its reliability has not been sufficiently examined. This study therefore investigated the between-session and within-subject test-retest reliability of EIH at local and remote body parts after aerobic cycling at a heart rate-controlled intensity. METHODS: Thirty healthy adults (15 women) performed 15 minutes of aerobic cycling in two sessions...
June 18, 2019: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://read.qxmd.com/read/31211382/intravenous-or-oral-acetaminophen-for-analgesia-after-cesarean-section-exposure-drives-pain-relief
#13
Paola Mian, André Dallmann, John N van den Anker, Dick Tibboel, Karel Allegaert
No abstract text is available yet for this article.
June 18, 2019: Pain Medicine
https://read.qxmd.com/read/31197321/cancer-related-pain-is-an-independent-predictor-of-in-hospital-opioid-overdose-a-propensity-matched-analysis
#14
Nnaemeka E Onyeakusi, Fahad Mukhtar, Semiu O Gbadamosi, Adebamike Oshunbade, Adeyinka C Adejumo, Olubode Olufajo, Jude Owoh
BACKGROUND: About 50% of patients with cancer who have undergone surgery suffer from cancer-related pain (CP). The use of opioids for postoperative pain management presents the potential for overdose, especially among these patients. OBJECTIVE: The primary objective of this study was to determine the association between CP and postoperative opioid overdose among inpatients who had undergone major elective procedures. The secondary objective was to assess the relationship between CP and inpatient mortality, total hospital charge, and length of stay in this population...
June 14, 2019: Pain Medicine
https://read.qxmd.com/read/31188448/serious-complications-associated-with-interventional-spine-procedures-results-of-a-spine-intervention-society-survey
#15
Nathan D Clements, Zachary L McCormick, Darrell Vydra, Ameet Nagpal, Venu Akuthota, David J Kennedy, Daniel M Cushman
No abstract text is available yet for this article.
June 12, 2019: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://read.qxmd.com/read/31184365/vial-coring
#16
Jaymin Patel, Clark C Smith
No abstract text is available yet for this article.
June 11, 2019: Pain Medicine
https://read.qxmd.com/read/31181148/the-effectiveness-of-fluoroscopically-guided-cervical-transforaminal-epidural-steroid-injection-for-the-treatment-of-radicular-pain-a-systematic-review-and-meta-analysis
#17
Aaron Conger, Daniel M Cushman, Rebecca A Speckman, Taylor Burnham, Masaru Teramoto, Zachary L McCormick
OBJECTIVE: Determine the effectiveness of fluoroscopically guided cervical transforaminal epidural steroid injection (CTFESI) for the treatment of radicular pain. DESIGN: Systematic review and meta-analysis. SUBJECTS: Persons aged ≥18 years with cervical radicular pain due to disc herniation or degenerative spondylosis. COMPARISON: Sham, placebo procedure, or active standard of care treatment, excluding alternative versions of epidural steroid injection...
June 10, 2019: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://read.qxmd.com/read/31169297/swabbing-vial-tops
#18
Jaymin Patel, Clark Smith
No abstract text is available yet for this article.
June 6, 2019: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://read.qxmd.com/read/31165895/a-multicenter-prospective-randomized-placebo-controlled-double-blind-study-of-a-novel-pain-management-device-at-02-in-patients-with-fibromyalgia
#19
Hiroshi Oka, Kenji Miki, Iwao Kishita, David F Kong, Takahiro Uchida
OBJECTIVES: Existing treatments for fibromyalgia have limited efficacy, and only a minority of individuals clinically respond to any single intervention. This study was a prospective, multicenter, randomized, double-blind, controlled clinical trial to evaluate the feasibility of alternating magnetic field therapy in fibromyalgia patients by comparing the Angel Touch device (AT-02) with a sham control (S-01). METHODS: Two sites enrolled 44 subjects with diagnosed fibromyalgia...
June 5, 2019: Pain Medicine
https://read.qxmd.com/read/31165894/electrical-pain-thresholds-and-conditioned-pain-modulation-in-patients-with-low-back-related-leg-pain-and-patients-with-failed-back-surgery-syndrome-a-cross-sectional-pilot-study
#20
Lisa Goudman, Eva Huysmans, Iris Coppieters, Kelly Ickmans, Jo Nijs, Ronald Buyl, Koen Putman, Maarten Moens
OBJECTIVE: When evaluating sensory dysfunctions and pain mechanisms in patients with low back pain (LBP), a specific subgroup of patients with radicular symptoms is often excluded. Comparative studies that evaluate sensory sensitivity in patients with a dominant nociceptive and neuropathic pain component are rarely performed. Therefore, the goal of this study was to examine differences in electrical thresholds and conditioned pain modulation (CPM) between patients with low back-related leg pain (LBRLP) and patients with failed back surgery syndrome (FBSS)...
June 5, 2019: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
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