Definition and Evolution of the Term Osteoporosis.

Osteoporosis is a metabolic bone disease in which the loss of bone mineral density causes the bone to become weaker and more susceptible to fracture. In the vulnerable individual, osteoporosis develops as a result of a combination of hereditary and environmental risk factors. The definition of the term osteoporosis as a clinical syndrome has evolved with the improved understanding of the pathogenesis, diagnostic terminology and treatment directions both pharmacological and non-pharmacological, over the past few decades.