An evidence map of clinical practice guideline recommendations and quality on venous leg ulcer.

SIGNIFICANCE: Venous leg ulcers (VLUs) are the most common venous disease, mainly presenting as open skin lesions on the legs or feet and are an important concern in clinical care settings.

RECENT ADVANCES: Comprehensive tactics were employed to search electronic databases PubMed, Embase, guideline databases, and society websites were searched for CPGs (Clinical Practice Guidelines) on VLU care. The basic information, recommendations for the VLUs, methodological quality, and reporting quality of VLUs CPGs were extracted and captured in Excel. The quality of each CPG was independently assessed by four researchers using AGREE II instrument and the RIGHT checklist.

CRITICAL ISSUES: This study included 19 CPGs with a combined 23 recommendations. The assessment of VLUs was summarized based on the recommendations of VLUs in eleven major items; six on VLUs diagnosis and six on therapeutic strategies of VLUs. The identified CPGs were of mixed quality, and the highest score based on the scope and purpose was 82.85± 11.66, whereas the lowest mean score based on the editorial independence by AGREE II was 59.93± 21.50. Regarding the RIGHT checklist, field one (basic information) had the highest reporting rate (84.33%), whereas field five (review and quality assurance) had the lowest quality CPGs (41.11%).

FUTURE DIRECTIONS: This evidence map provided new perspectives in the presentation of evidence. In addition, the evidence map collected and evaluated the characteristics of published CPGs. Thus, the evidence map enhances our knowledge and promotes the development of trustworthy CPGs for VLUs.