Bioactive glass and arginine dentifrices reduce root sensitivity during daily activities following non-surgical periodontal therapy: A randomized clinical trial.

BACKGROUND: Evidence on the efficacy of calcium sodium phosphosilicate (CSPS) and arginine dentifrices on reducing root sensitivity (RS) following non-surgical periodontal therapy (NSPT) is limited. The aim of the study was to compare the efficacy of these dentifrices in reducing RS during daily activities in patients undergoing NSPT.

METHODS: Using a double-blind randomized controlled trial, CSPS, arginine or control dentifrices were randomly assigned to forty-five RS individuals following NSPT. The participants used the dentifrices 2x/day for 8 weeks. A self-reported visual analog scale (VAS) was assessed during daily activities.

RESULTS: Self-reported VAS scores were similar among the three groups at each time point. The with-in group analysis revealed that the arginine dentifrice reduced RS from week 1-8 compared with baseline in response to cold. Similarly, the CSPS dentifrice reduced RS at week 4 and 8. The CSPS and arginine dentifrices exhibited RS relief resulting from toothbrushing starting at week 4 and 2, respectively. In response to air, RS relief was observed from week 4 in the arginine group. The number of patients with VAS>2 in response to cold declined at week 2 and 4 in the CSPS and arginine groups, respectively. In response to toothbrushing, only 10% in the test groups still had RS at week 8. In response to air, the number of RS patients only in the arginine group decreased at week 4.

CONCLUSION: The CSPS and arginine dentifrices provided comparable RS relief during daily activities within 2-4 weeks and remained effective up to 8 weeks. This article is protected by copyright. All rights reserved.