We have located links that may give you full text access.
Impact of the new ultra-high sensitivity mode in a long axial field-of-view PET/CT.
Annals of Nuclear Medicine 2023 March 14
OBJECTIVE: Long axial field-of-view (LAFOV) PET/CT showed improved performance resulting from higher sensitivity. The aim was to quantify the impact of using the full acceptance angle (UHS) in image reconstructions with the Biograph Vision Quadra LAFOV PET/CT (Siemens Healthineers) compared to the limited acceptance angle (high sensitivity mode, HS).
METHODS: 38 oncological patients examined on a LAFOV Biograph Vision Quadra PET/CT were analysed. 15 patients underwent [18 F]FDG-PET/CT, 15 patients underwent [18 F]PSMA-1007 PET/CT, and 8 patients underwent [68 Ga]Ga-DOTA-TOC PET/CT. Signal-to-noise ratio (SNR) and standardised uptake values (SUVmean/max/peak ) were used to compare UHS and HS with different acquisition times.
RESULTS: The SNR was significantly higher for UHS compared to HS over all acquisition times (SNR UHS/HS [18 F]FDG: 1.35 ± 0.02, p < 0.001; [18 F]PSMA-1007: 1.25 ± 0.02, p < 0.001; [68 Ga]Ga-DOTA-TOC: 1.29 ± 0.02, p < 0.001).
CONCLUSION: UHS showed significantly higher SNR opening the possibility of halving short acquisition times. This is of advantage in further reduction of whole-body PET/CT acquisition.
METHODS: 38 oncological patients examined on a LAFOV Biograph Vision Quadra PET/CT were analysed. 15 patients underwent [18 F]FDG-PET/CT, 15 patients underwent [18 F]PSMA-1007 PET/CT, and 8 patients underwent [68 Ga]Ga-DOTA-TOC PET/CT. Signal-to-noise ratio (SNR) and standardised uptake values (SUVmean/max/peak ) were used to compare UHS and HS with different acquisition times.
RESULTS: The SNR was significantly higher for UHS compared to HS over all acquisition times (SNR UHS/HS [18 F]FDG: 1.35 ± 0.02, p < 0.001; [18 F]PSMA-1007: 1.25 ± 0.02, p < 0.001; [68 Ga]Ga-DOTA-TOC: 1.29 ± 0.02, p < 0.001).
CONCLUSION: UHS showed significantly higher SNR opening the possibility of halving short acquisition times. This is of advantage in further reduction of whole-body PET/CT acquisition.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app