Effects of off-pump coronary artery bypass grafting on clinical efficacy, cardiac function and the incidence of major adverse cardiovascular events in patients with coronary heart disease.

OBJECTIVE: To explore the effects of off-pump coronary artery bypass grafting (OPC) on clinical efficacy, cardiac function and the occurrence of major adverse cardiovascular events (MACE) in patients with coronary heart disease.

METHODS: According to different surgical methods, 93 patients with coronary heart disease who were hospitalized and treated in our hospital were collapsed into the off-pump coronary artery bypass grafting group (OPC group) and the extracorporeal circulation coronary artery bypass grafting group (PC group). The perioperative indexes, cardiac function indexes, postoperative recovery, quality of life, the incidence of MACE and adverse reactions and the survival rate of patients in PC group and OPC group were analyzed and compared.

RESULTS: Compared with the PC group, the operation time and blood transfusion volume of OPC group were both largely decreased (P<0.05), but the number of bypass grafts was similar (P>0.05). The cardiac function index of OPC group was much higher than that of PC group (P<0.05). The postoperative recovery after operation of OPC group was better than that of PC group (P<0.05). The scores of quality of life scale in OPC group were markedly higher than those in PC group (P<0.05). The incidence of MACE in OPC group was obviously lower than that in PC group (P<0.05). Patients in in the OPC group had slightly lower incidence of adverse reactions, and slightly higher survival rate than the PC group, but there was no statistical difference (P>0.05).

CONCLUSION: Compared with PC, OPC has a significantly better therapeutic effect on patients with coronary heart disease, which can significantly improve the perioperative indices and cardiac function, and enhance the quality of life of patients.